메뉴 건너뛰기




Volumn 27, Issue 11, 2006, Pages 2316-2321

Lower mutagenicity but higher stability of Cr-DNA adducts formed during gradual chromate activation with ascorbate

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; CHELATING AGENT; CHROMIC ACID; CHROMIUM; CHROMIUM DERIVATIVE; DICHLORODIHYDROFLUORESCEIN DIACETATE; DNA;

EID: 33750490455     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgl076     Document Type: Article
Times cited : (23)

References (37)
  • 1
    • 0025239336 scopus 로고
    • One hundred years of chromium and cancer: A review of epidemiological evidence and selected case reports
    • Langard,S. (1990) One hundred years of chromium and cancer: A review of epidemiological evidence and selected case reports. Am. J. Ind. Med., 17, 189-215.
    • (1990) Am. J. Ind. Med. , vol.17 , pp. 189-215
    • Langard, S.1
  • 3
    • 0033945125 scopus 로고    scopus 로고
    • Lung cancer among workers in chromium chemical production
    • Gibb,H.J., Lees,P.S.J., Pinsky,P.F. and Rooney,B.C. (2000) Lung cancer among workers in chromium chemical production. Am. J. Ind. Med., 38, 115-126.
    • (2000) Am. J. Ind. Med. , vol.38 , pp. 115-126
    • Gibb, H.J.1    Lees, P.S.J.2    Pinsky, P.F.3    Rooney, B.C.4
  • 4
    • 12144270899 scopus 로고    scopus 로고
    • Importance of chromium-DNA adducts in mutagenicity and toxicity of chromium(VI)
    • Zhitkovich,A. (2005) Importance of chromium-DNA adducts in mutagenicity and toxicity of chromium(VI). Chem. Res. Toxicol., 18, 3-11.
    • (2005) Chem. Res. Toxicol. , vol.18 , pp. 3-11
    • Zhitkovich, A.1
  • 5
    • 0025864517 scopus 로고
    • Ascorbate is the principal reductant of chromium(VI) in rat liver and kidney ultrafiltrates
    • Standeven,A.M. and Wetterhahn,K.E. (1991) Ascorbate is the principal reductant of chromium(VI) in rat liver and kidney ultrafiltrates. Carcinogenesis, 12, 1733-1737.
    • (1991) Carcinogenesis , vol.12 , pp. 1733-1737
    • Standeven, A.M.1    Wetterhahn, K.E.2
  • 6
    • 0026787562 scopus 로고
    • Ascorbate is the principal reductant of chromium(VI) in rat lung ultrafiltrates and cytosols, and mediates chromium-DNA binding in vitro
    • Standeven,A.M. and Wetterhahn,K.E. (1992) Ascorbate is the principal reductant of chromium(VI) in rat lung ultrafiltrates and cytosols, and mediates chromium-DNA binding in vitro. Carcinogenesis, 13, 1319-1324.
    • (1992) Carcinogenesis , vol.13 , pp. 1319-1324
    • Standeven, A.M.1    Wetterhahn, K.E.2
  • 7
    • 0037417782 scopus 로고    scopus 로고
    • Genotoxicity and mutagenicity of chromium(VI)/ascorbate-generated DNA adducts in human and bacterial cells
    • Quievryn,G., Peterson,E., Messer,J. and Zhitkovich,A. (2003) Genotoxicity and mutagenicity of chromium(VI)/ascorbate-generated DNA adducts in human and bacterial cells. Biochemistry, 42, 1062-1070.
    • (2003) Biochemistry , vol.42 , pp. 1062-1070
    • Quievryn, G.1    Peterson, E.2    Messer, J.3    Zhitkovich, A.4
  • 8
    • 0033856350 scopus 로고    scopus 로고
    • The role of chromium(V) in the mechanism of chromate-induced oxidative DNA damage and cancer
    • Sugden,K.D. and Stearns,D.M. (2000) The role of chromium(V) in the mechanism of chromate-induced oxidative DNA damage and cancer. J. Environ. Pathol. Toxicol. Oncol., 19, 215-230.
    • (2000) J. Environ. Pathol. Toxicol. Oncol. , vol.19 , pp. 215-230
    • Sugden, K.D.1    Stearns, D.M.2
  • 9
    • 45949124049 scopus 로고
    • EPR study of the Cr(V) and radical species produced in the reduction of Cr(VI) by ascorbate
    • Goodgame,D.M.L. and Joy,M.A. (1987) EPR study of the Cr(V) and radical species produced in the reduction of Cr(VI) by ascorbate. Inorg. Chim. Acta, 135, 115-118.
    • (1987) Inorg. Chim. Acta , vol.135 , pp. 115-118
    • Goodgame, D.M.L.1    Joy, M.A.2
  • 10
    • 0028354494 scopus 로고
    • Reaction of Cr(VI) with ascorbate produces chromium(V), chromium(IV), and carbon-based radicals
    • Stearns,D.M. and Wetterhahn,K.E. (1994) Reaction of Cr(VI) with ascorbate produces chromium(V), chromium(IV), and carbon-based radicals. Chem. Res. Toxicol., 7, 219-230.
    • (1994) Chem. Res. Toxicol. , vol.7 , pp. 219-230
    • Stearns, D.M.1    Wetterhahn, K.E.2
  • 11
    • 0032527711 scopus 로고    scopus 로고
    • Activation of molecular oxygen during the reactions of chromium(VI/V/IV) with biological reductants: Implications for chromium-induced genotoxicities
    • Lay,P.A. and Levina,A. (1998) Activation of molecular oxygen during the reactions of chromium(VI/V/IV) with biological reductants: Implications for chromium-induced genotoxicities. J. Am. Chem. Soc., 120, 6704-6714.
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 6704-6714
    • Lay, P.A.1    Levina, A.2
  • 12
    • 0032702701 scopus 로고    scopus 로고
    • Chromium(VI)-mediated DNA damage: Oxidative pathways resulting in the formation of DNA breaks and abasic sites
    • Casadevall,M., da Cruz Fresco,P. and Kortenkamp,A. (1999) Chromium(VI)-mediated DNA damage: Oxidative pathways resulting in the formation of DNA breaks and abasic sites. Chem. Biol. Interact., 123, 117-132.
    • (1999) Chem. Biol. Interact. , vol.123 , pp. 117-132
    • Casadevall, M.1    da Cruz Fresco, P.2    Kortenkamp, A.3
  • 13
    • 0037108104 scopus 로고    scopus 로고
    • Critical role of chromium (Cr)-DNA interactions in the formation of Cr-induced polymerase arresting lesions
    • O'Brien,T., Mandel,H.G., Pritchard,D.E. and Patierno,S.R. (2002) Critical role of chromium (Cr)-DNA interactions in the formation of Cr-induced polymerase arresting lesions. Biochemistry, 41, 12529-12537.
    • (2002) Biochemistry , vol.41 , pp. 12529-12537
    • O'Brien, T.1    Mandel, H.G.2    Pritchard, D.E.3    Patierno, S.R.4
  • 14
    • 22544434922 scopus 로고    scopus 로고
    • Guanine-specific oxidation of double-stranded DNA by Cr(VI) and ascorbic acid forms spiroiminodihydantoin and 8-oxo-2′-deoxyguanosine
    • Slade,P.G., Hailer,M.K., Martin,B.D. and Sugden,K.D. (2005) Guanine-specific oxidation of double-stranded DNA by Cr(VI) and ascorbic acid forms spiroiminodihydantoin and 8-oxo-2′-deoxyguanosine. Chem. Res. Toxicol., 18, 1140-1149.
    • (2005) Chem. Res. Toxicol. , vol.18 , pp. 1140-1149
    • Slade, P.G.1    Hailer, M.K.2    Martin, B.D.3    Sugden, K.D.4
  • 15
    • 0034008164 scopus 로고    scopus 로고
    • Threshold mechanisms and site specificity in chromium(VI) carcinogenesis
    • De Flora,S. (2000) Threshold mechanisms and site specificity in chromium(VI) carcinogenesis. Carcinogenesis, 21, 533-541.
    • (2000) Carcinogenesis , vol.21 , pp. 533-541
    • De Flora, S.1
  • 16
    • 0028937564 scopus 로고
    • Glutathione and free amino acids form stable adducts with DNA following expense of intact mammalian cells to chromate
    • Zhitkovich,A., Voitkun,V. and Costa,M. (1995) Glutathione and free amino acids form stable adducts with DNA following expense of intact mammalian cells to chromate. Carcinogenesis, 16, 907-913.
    • (1995) Carcinogenesis , vol.16 , pp. 907-913
    • Zhitkovich, A.1    Voitkun, V.2    Costa, M.3
  • 17
    • 0037022823 scopus 로고    scopus 로고
    • Carcinogenic chromium(VI) induces cross-linking of vitamin C to DNA in vitro and in human lung A549 cells
    • Quievryn,G., Messer,J. and Zhitkovich,A. (2002) Carcinogenic chromium(VI) induces cross-linking of vitamin C to DNA in vitro and in human lung A549 cells. Biochemistry, 41, 3156-3167.
    • (2002) Biochemistry , vol.41 , pp. 3156-3167
    • Quievryn, G.1    Messer, J.2    Zhitkovich, A.3
  • 18
    • 8844227489 scopus 로고    scopus 로고
    • Hexavalent chromium and lung cancer in the chromate industry: A quantitative risk assessment
    • Park,R.M., Bena,J.F., Stayner,L.T., Smith,R.J., Gibb,H.J. and Lees,P.S, (2004) Hexavalent chromium and lung cancer in the chromate industry: A quantitative risk assessment. Risk Anal., 24, 1099-1108.
    • (2004) Risk Anal. , vol.24 , pp. 1099-1108
    • Park, R.M.1    Bena, J.F.2    Stayner, L.T.3    Smith, R.J.4    Gibb, H.J.5    Lees, P.S.6
  • 19
    • 0033681748 scopus 로고    scopus 로고
    • Reductive metabolism of Cr(VI) by cysteine leads to the formation of binary and ternary Cr-DNA adducts in the absence of oxidative DNA damage
    • Zhitkovich,A., Messer,J. and Shrager,S. (2000) Reductive metabolism of Cr(VI) by cysteine leads to the formation of binary and ternary Cr-DNA adducts in the absence of oxidative DNA damage. Chem. Res. Toxicol., 13, 1114-1124.
    • (2000) Chem. Res. Toxicol. , vol.13 , pp. 1114-1124
    • Zhitkovich, A.1    Messer, J.2    Shrager, S.3
  • 20
    • 0026637161 scopus 로고
    • A signature element distinguishes sibling and independent mutations in a shuttle vector plasmid
    • Parris,C.N. and Seidman,M.M. (1992) A signature element distinguishes sibling and independent mutations in a shuttle vector plasmid. Gene, 117, 1-5.
    • (1992) Gene , vol.117 , pp. 1-5
    • Parris, C.N.1    Seidman, M.M.2
  • 21
    • 0027294614 scopus 로고
    • A method for selection of forward mutations in supF gene carried by shuttle-vector plasmids
    • Ariza,R.R., Roldan-Arjona,T., Hera,C. and Pueyo,C. (1993) A method for selection of forward mutations in supF gene carried by shuttle-vector plasmids. Carcinogenesis, 14, 303-305.
    • (1993) Carcinogenesis , vol.14 , pp. 303-305
    • Ariza, R.R.1    Roldan-Arjona, T.2    Hera, C.3    Pueyo, C.4
  • 22
    • 0026038362 scopus 로고
    • Plasmid transformation of Escherichia coli and other bacteria
    • Hanahan,D., Jessee,J. and Bloom,F.R. (1991) Plasmid transformation of Escherichia coli and other bacteria. Methods Enzymol., 204, 83-88.
    • (1991) Methods Enzymol. , vol.204 , pp. 83-88
    • Hanahan, D.1    Jessee, J.2    Bloom, F.R.3
  • 23
    • 0035895349 scopus 로고    scopus 로고
    • Non-oxidative mechanisms are responsible for the induction of mutagenesis by reduction of Cr(VI) with cysteine: Role of ternary DNA adducts in Cr(III)-dependent mutagenesis
    • Zhitkovich,A., Song,Y., Quievryn,G. and Voitkun,V. (2001) Non-oxidative mechanisms are responsible for the induction of mutagenesis by reduction of Cr(VI) with cysteine: Role of ternary DNA adducts in Cr(III)-dependent mutagenesis. Biochemistry, 40, 549-560.
    • (2001) Biochemistry , vol.40 , pp. 549-560
    • Zhitkovich, A.1    Song, Y.2    Quievryn, G.3    Voitkun, V.4
  • 24
    • 33646566825 scopus 로고    scopus 로고
    • Causes of DNA single-strand breaks during reduction of chromate by glutathione in vitro and in cells
    • Messer,J., Reynolds,M., Stoddard,L. and Zhitkovich,A. (2006) Causes of DNA single-strand breaks during reduction of chromate by glutathione in vitro and in cells. Free Radic. Biol. Med., 40, 1981-1992.
    • (2006) Free Radic. Biol. Med. , vol.40 , pp. 1981-1992
    • Messer, J.1    Reynolds, M.2    Stoddard, L.3    Zhitkovich, A.4
  • 25
    • 0034808208 scopus 로고    scopus 로고
    • Reduction of Cr(VI) by cysteine: Significance in human lymphocytes and formation of DNA damage in reactions with variable reduction rates
    • Quievryn,G., Goulart,M., Messer,J. and Zhitkovich,A. (2001) Reduction of Cr(VI) by cysteine: Significance in human lymphocytes and formation of DNA damage in reactions with variable reduction rates. Mol. Cell. Biochem., 222, 107-118.
    • (2001) Mol. Cell. Biochem. , vol.222 , pp. 107-118
    • Quievryn, G.1    Goulart, M.2    Messer, J.3    Zhitkovich, A.4
  • 26
    • 0032428645 scopus 로고    scopus 로고
    • Hypervalent chromium mimics reactive oxygen species as measured by the oxidant-sensitive dyes 2′,7′-dichlorofluorescin and dihydrorhodamine
    • Martin,B.D., Schoenhard,J.A. and Sugden,K.D. (1998) Hypervalent chromium mimics reactive oxygen species as measured by the oxidant-sensitive dyes 2′,7′-dichlorofluorescin and dihydrorhodamine. Chem. Res. Toxicol., 11, 1402-1410.
    • (1998) Chem. Res. Toxicol. , vol.11 , pp. 1402-1410
    • Martin, B.D.1    Schoenhard, J.A.2    Sugden, K.D.3
  • 27
    • 0028100575 scopus 로고
    • The formation of DNA cleaving species during the reduction of chromate by ascorbate
    • da Cruz Fresco,P. and Kortenkamp,A. (1994) The formation of DNA cleaving species during the reduction of chromate by ascorbate. Carcinogenesis, 15, 1773-1778.
    • (1994) Carcinogenesis , vol.15 , pp. 1773-1778
    • da Cruz Fresco, P.1    Kortenkamp, A.2
  • 28
    • 0029099394 scopus 로고
    • The reductive conversion of chromium(VI) by ascorbate gives rise to apurinic/apyrimidinic sites in isolated DNA
    • da Cruz Fresco,P., Shacker,F. and Kortenkamp,A. (1995) The reductive conversion of chromium(VI) by ascorbate gives rise to apurinic/ apyrimidinic sites in isolated DNA. Chem. Res. Toxicol., 8, 884-890.
    • (1995) Chem. Res. Toxicol. , vol.8 , pp. 884-890
    • da Cruz Fresco, P.1    Shacker, F.2    Kortenkamp, A.3
  • 29
    • 0030466434 scopus 로고    scopus 로고
    • EPR spectroscopic studies of the reactions of Cr(VI) with L-ascorbic acid, L-dehydroascorbic acid, and 5,6-o-isopropylidene-L-ascorbic acid in water. Implications for chromium(VI) genotoxicity
    • Zhang,Z. and Lay,P.A. (1996) EPR spectroscopic studies of the reactions of Cr(VI) with L-ascorbic acid, L-dehydroascorbic acid, and 5,6-o-isopropylidene-L-ascorbic acid in water. Implications for chromium(VI) genotoxicity. J. Am. Chem. Soc., 118, 12624-12637.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 12624-12637
    • Zhang, Z.1    Lay, P.A.2
  • 30
    • 0032527711 scopus 로고    scopus 로고
    • Activation of molecular oxygen during the reactions of chromium(VI/V/IV) with biological reductants: Implications for chromium-induced genotoxicities
    • Lay,P.A. and Levina,A. (1998) Activation of molecular oxygen during the reactions of chromium(VI/V/IV) with biological reductants: Implications for chromium-induced genotoxicities. J. Am. Chem. Soc., 120, 6704-6714.
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 6704-6714
    • Lay, P.A.1    Levina, A.2
  • 32
    • 0035009313 scopus 로고    scopus 로고
    • Mammalian DNA single-strand break repair: An X-ra(y)ted affair
    • Caldecott,K.W. (2001) Mammalian DNA single-strand break repair: An X-ra(y)ted affair. Bioessays, 23, 447-55.
    • (2001) Bioessays , vol.23 , pp. 447-455
    • Caldecott, K.W.1
  • 33
    • 3142782144 scopus 로고    scopus 로고
    • Human nucleotide excision repair efficiently removes chromium-DNA phosphate adducts and protects cells against chromate toxicity
    • Reynolds,M., Peterson,E., Quievryn,G. and Zhitkovich,A. (2004) Human nucleotide excision repair efficiently removes chromium-DNA phosphate adducts and protects cells against chromate toxicity. J. Biol. Chem. 279, 30419-30424.
    • (2004) J. Biol. Chem. , vol.279 , pp. 30419-30424
    • Reynolds, M.1    Peterson, E.2    Quievryn, G.3    Zhitkovich, A.4
  • 34
    • 0029943628 scopus 로고    scopus 로고
    • Formation of the amino acid-DNA complexes by hexavalent and trivalent chromium in vitro: Importance of trivalent chromium and the phosphate group
    • Zhitkovich,A., Voitkun,V. and Costa,M. (1996) Formation of the amino acid-DNA complexes by hexavalent and trivalent chromium in vitro: importance of trivalent chromium and the phosphate group. Biochemistry, 35, 7275-7282.
    • (1996) Biochemistry , vol.35 , pp. 7275-7282
    • Zhitkovich, A.1    Voitkun, V.2    Costa, M.3
  • 36
    • 17644377918 scopus 로고    scopus 로고
    • Mismatch repair proteins are activators of toxic responses to chromium-DNA damage
    • Peterson-Roth,E., Reynolds,M., Quievryn,G. and Zhitkovich,A. (2005) Mismatch repair proteins are activators of toxic responses to chromium-DNA damage. Mol. Cell. Biol., 25, 3596-3607.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 3596-3607
    • Peterson-Roth, E.1    Reynolds, M.2    Quievryn, G.3    Zhitkovich, A.4
  • 37
    • 25444454022 scopus 로고    scopus 로고
    • Killing of chromium-damaged cells by mismatch repair and its relevance to carcinogenesis
    • Zhitkovich,A., Peterson-Roth,E, and Reynolds,M. (2005) Killing of chromium-damaged cells by mismatch repair and its relevance to carcinogenesis. Cell Cycle, 4, 1050-1052.
    • (2005) Cell Cycle , vol.4 , pp. 1050-1052
    • Zhitkovich, A.1    Peterson-Roth, E.2    Reynolds, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.