Reductive metabolism of cr(VI) by cysteine leads to the formation of binary and ternary Cr-DNA adducts in the absence of oxidative DNA damage

Chemical Research in Toxicology

Volumn 13, Issue 11, 2000, Pages 1114-1124

  Zhitkovich, A ^a   Shrager, S ^a   Messer, J ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMIUM; CYSTEINE; DOUBLE STRANDED DNA;

ARTICLE; BINDING COMPETITION; CROSS LINKING; DNA ADDUCT; DNA BINDING; DNA DAMAGE; DNA DENATURATION; DNA STRAND BREAKAGE; GENOTOXICITY; METABOLISM; MOLECULAR STABILITY; OXIDATION; PH; REDUCTION;

ANIMALS; BUFFERS; CATIONS; CATTLE; CHROMATES; CHROMIUM COMPOUNDS; CYSTEINE; DNA ADDUCTS; DNA DAMAGE; DNA, SUPERHELICAL; DRUG STABILITY; FLUORESCEINS; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; KINETICS; OXIDATION-REDUCTION; REDUCING AGENTS;

EID: 0033681748     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0001169     Document Type: Article

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