Inhibition of protein kinase C ζ blocks the attachment of stable microtubules to kinetochores leading to abnormal chromosome alignment

Cellular Signalling

Volumn 18, Issue 12, 2006, Pages 2314-2323

  Liu, Xiu Fen ^a   Xie, Xiaozhen ^a   Miki, Toru ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Chromosome separation; Mitosis; Par3; Par6; Stable microtubules

Indexed keywords

CENTROMERE PROTEIN E; PROTEIN; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE C ZETA; PROTEIN MAD2; PROTEIN PAR3; PROTEIN PAR6; THREONINE; UNCLASSIFIED DRUG;

ANAPHASE; ARTICLE; CELL DIVISION; CELL POLARITY; CENTROMERE; CHROMOSOME ABERRATION; CHROMOSOME SEGREGATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; METAPHASE; MICROTUBULE ASSEMBLY; MITOSIS; MITOSIS SPINDLE; PRIORITY JOURNAL; PROMETAPHASE; PROTEIN FUNCTION; RNA INTERFERENCE; TELOPHASE;

CARRIER PROTEINS; CHROMOSOME SEGREGATION; CYTOKINESIS; HELA CELLS; HUMANS; KINETOCHORES; LUCIFERASES; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RNA INTERFERENCE; RNA, SMALL INTERFERING; THREONINE; TRANSFECTION;

EID: 33750330749     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2006.05.017     Document Type: Article

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