Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells

BMC Cancer

Volumn 6, Issue , 2006, Pages

  Fuerer, Christophe ^a   Homicsko, Krisztian ^a   Lukashev, Alexander N ^a   Pittet, Anne Laure ^a   Iggo, Richard D ^a,b  

^a SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTINEOPLASTIC AGENT; BCL 9 HOMOLOGY DOMAIN 2 EIA FUSION PROTEIN; BETA CATENIN; LUCIFERASE; ONCOLYTIC VIRUS; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; WNT PROTEIN;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; COLON CANCER; CYTOPATHOGENIC EFFECT; CYTOTOXICITY; DOWNSTREAM PROCESSING; FEMALE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GROWTH CURVE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; VIRUS REPLICATION; WESTERN BLOTTING; WILD TYPE;

ADENOVIRUS E1A PROTEINS; ANIMALS; BETA CATENIN; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYTOPATHOGENIC EFFECT, VIRAL; FEMALE; GENE FUSION; HELA CELLS; HUMANS; MICE; MICE, NUDE; NEOPLASM PROTEINS; ONCOLYTIC VIRUSES; SIGNAL TRANSDUCTION; WNT PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 33750233801     PISSN: 14712407     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-6-236     Document Type: Article

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