Dolly, no longer the exception: Telomeres and implications for transplantation

Cloning and Stem Cells

Volumn 5, Issue 2, 2003, Pages 157-160

  Shiels, P G ^a   Jardine, A G ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS TRANSPLANTATION; CLONING; CUMULUS OOPHORUS; DNA DAMAGE; DNA REPAIR; GENE CONTROL; NONHUMAN; NOTE; PRIORITY JOURNAL; RESTRICTION FRAGMENT; TELOMERE;

EID: 0038299399     PISSN: 15362302     EISSN: None     Source Type: Journal    
DOI: 10.1089/153623003322234768     Document Type: Note

References (22)

1. Betts, D., Bordignon, V., Hill, J., et al. (2001). Reprogramming of telomerase activity and rebuilding of telomere length in cloned cattle. Proc. Natl. Acad. Sci. USA 98, 1077-1082.
2. Broccoli, D., Chong, L., Oelmann, S., et al. (1997). Comparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domains. Hum. Mol. Genet. 1, 69-76.
3. Cui, W., Aslam, S., Fletcher, J., et al. (2002). Stabilization of telomere length and karyotypic stability are directly correlated with the level of hTERT gene expression in primary fibroblasts. J. Biol. Chem. 277, 38531-38539.
4. Gorbunova, V., Seluanov, A., and Pereira-Smith, O.M. (2002). Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis. J. Biol. Chem. 277, 38540-38549.
5. Halloran, P.F., Melk, A., and Barth, C. (1999). Rethinking chronic allograft nephropathy: the concept of accelerated senescence. J. Am. Soc. Nephrol. 10, 167-181.
6. Henson, J.D., Neumann, A.A., Yeager, T.R., et al. (2002). Alternative lengthening of telomeres in mammalian cells. Oncogene, 21, 598-610.
7. Humpherys, D., Eggan, K., Akutsu, H., et al. (2002). Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei. Proc. Natl. Acad. Sci. USA 99, 12889-12894.
8. Joosten, S.A., van Ham, V., Nolan, C.E., Borrias, M.C., Jardine, A.G., Shiels, P.G. Van Kooten, C., and Paul, L.C. (2003). Telomere shortening and cellular senescence in a model of chronic renal allograft rejection. Am. J. Pathol. 162, 1305-1312.
9. Kubota, C., Yamakuchi, H., Todoroki, J., et al. (2000). Six cloned calves produced from adult fibroblast cells after long-term culture. Proc. Natl. Acad. Sci. USA 97, 990-995.
10. Lanza, R.P., Cibelli, J.B., Blackwell, C., et al. (2000). Extension of cell life-span and telomere length in animals cloned from senescent somatic cells. Science 288, 665-669.
11. Minamino, T., and Komuro, I. (2002). Role of telomere in endothelial dysfunction in atherosclerosis. Curr. Opin. Lipidol. 13, 537-543.
12. Miyashita, N., Shiga, K., Yonai, M., et al. (2002). Remarkable differences in telomere lengths among cloned cattle derived from different cell types. Biol. Reprod. 66, 1649-1655.
13. Ogonuki, N., Inoue, K., Yamamoto, Y., et al. (2002). Early death of mice cloned from somatic cells. Nat. Genet. 30, 253-254.
14. Ramirez, R., Carracedo, J., Jimenez, R., Camela, A., Herrera, E., Aljama, P., and Blasco, M.A. (2003). Massive telomere loss is an early event of DNA damage-induced apoptosis. J. Biol. Chem. 278, 836-842.
15. Shiels, P.G., Kind, A.J., Campbell, K.H., et al. (1999a). Analysis of telomere lengths in cloned sheep. Nature 399, 316-317.
16. Shiels, P.G., Kind, A.J., Campbell, K.H., et al. (1999b). Analysis of telomere length in Dolly, a sheep derived by nuclear transfer. Cloning, 1, 1-7.
17. Shiels, P.G. (1999c). Somatic cell nuclear transfer as a tool for investigating ageing processes in mammals. Gene Ther. Mol. Biol. 4, 11-22.
18. Shiels, P.G., Nolan, C.E., and Sklavounou, E. (2003). Cellular senescence, organ ageing and renal pathogenesis. Am. J. Transplant. (submitted).
19. Tamashiro, K.L., Wakayama, T., Akutsu, H., et al. (2002). Cloned mice have an obese phenotype not transmitted to their offspring. Nat. Med. 8, 262-267.
20. Tian, X.C., Xu, J., and Yang, X. (2000). Normal telomere lengths found in cloned cattle. Nat. Genet. 26, 272-273.
21. van Steensel, B., and de Lange, T. (1997). Control of telomere length by the human telomeric protein TRF1. Nature 385, 740-743.
22. Wakayama, T., Shinkai, Y., Tamashiro, K., et al. (2000). Cloning of mice to six generations. Nature 407, 318-319.