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Volumn 99, Issue 3, 2006, Pages 839-849

Growth hormone releasing peptide-6 acts as a survival factor in glutamate-induced excitotoxicity

Author keywords

Cerebellum; Ghrelin; Glutamate; Growth hormone secretagogues; Hypothalamus; Neuroprotection

Indexed keywords

CASPASE 7; CASPASE 9; GHRELIN; GHRELIN RECEPTOR; GLUTAMATE SODIUM; GLUTAMIC ACID; HISTIDYL DEXTRO TRYPTOPHYLALANYLTRYPTOPHYL DEXTRO PHENYLALANYLLYSINAMIDE; HORMONE RECEPTOR; HORMONE RECEPTOR STIMULATING AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SOMATOMEDIN C; UNCLASSIFIED DRUG;

EID: 33750083018     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04122.x     Document Type: Article
Times cited : (29)

References (39)
  • 1
    • 0037164747 scopus 로고    scopus 로고
    • Ghrelin and desacylghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI3-kinase/AKT
    • Baldanzi G., Filigheddu N., Cutrupi S., et al. (2002) Ghrelin and desacylghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI3-kinase/AKT. J. Cell Biol. 159, 1029-1037.
    • (2002) J. Cell Biol. , vol.159 , pp. 1029-1037
    • Baldanzi, G.1    Filigheddu, N.2    Cutrupi, S.3
  • 2
    • 0027085867 scopus 로고
    • Mechanisms of excitotoxicity in neurologic diseases
    • Beal M. F. (1992) Mechanisms of excitotoxicity in neurologic diseases. FASEB J. 6, 3338-33344.
    • (1992) FASEB J. , vol.6 , pp. 3338-33344
    • Beal, M.F.1
  • 3
    • 0035828123 scopus 로고    scopus 로고
    • Delayed application of IGF-I and GDNF can rescue already injured postnatal motor neurons
    • Bilak M. M. and Kuncl R. W. (2001) Delayed application of IGF-I and GDNF can rescue already injured postnatal motor neurons. Neuroreport 12, 2531-2535.
    • (2001) Neuroreport , vol.12 , pp. 2531-2535
    • Bilak, M.M.1    Kuncl, R.W.2
  • 4
    • 4143083990 scopus 로고    scopus 로고
    • Distinct requirement for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death
    • Cao J., Semenova M. M., Solovyan V. T., Han J., Coffey E. T. and Courtney M. J. (2004) Distinct requirement for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death. J. Biol. Chem. 279, 35 903-35 913.
    • (2004) J. Biol. Chem. , vol.279 , pp. 35903-35913
    • Cao, J.1    Semenova, M.M.2    Solovyan, V.T.3    Han, J.4    Coffey, E.T.5    Courtney, M.J.6
  • 5
    • 4644337673 scopus 로고    scopus 로고
    • Glutamate induced apoptosis in anterior pituitary cells through group II metabotropic glutamate receptor activation
    • Caruso C., Bottino M. C., Pampillo M., Pisera D., Jaita G., Duvilanski B., Seilicovich A. and Lasaga M. (2004) Glutamate induced apoptosis in anterior pituitary cells through group II metabotropic glutamate receptor activation. Endocrinology 145, 4677-4684.
    • (2004) Endocrinology , vol.145 , pp. 4677-4684
    • Caruso, C.1    Bottino, M.C.2    Pampillo, M.3    Pisera, D.4    Jaita, G.5    Duvilanski, B.6    Seilicovich, A.7    Lasaga, M.8
  • 6
    • 0033213973 scopus 로고    scopus 로고
    • Caspase and calpain substrates: Roels in synaptic plasticity and cell death
    • Chan S. L. and Mattson M. P. (1999) Caspase and calpain substrates: roels in synaptic plasticity and cell death. J. Neurosci. Res. 58, 167-190.
    • (1999) J. Neurosci. Res. , vol.58 , pp. 167-190
    • Chan, S.L.1    Mattson, M.P.2
  • 7
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L. and Karin M. (2001) Mammalian MAP kinase signalling cascades. Nature 410, 37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 8
    • 0031674855 scopus 로고    scopus 로고
    • Effects of repeated doses and continuous infusions of the growth hormone-releasing peptide hexarelin in conscious male rats
    • Conley L. K., Gaillar R. C., Giustina A., Brogan R. S. and Wehrenberg W. B. (1998) Effects of repeated doses and continuous infusions of the growth hormone-releasing peptide hexarelin in conscious male rats. J Endocrinol. 158, 367-375.
    • (1998) J Endocrinol. , vol.158 , pp. 367-375
    • Conley, L.K.1    Gaillar, R.C.2    Giustina, A.3    Brogan, R.S.4    Wehrenberg, W.B.5
  • 10
    • 0030330547 scopus 로고    scopus 로고
    • The role of the insulin-like growth factors in the central nervous system
    • D'Ercole A. J., Ye P., Calikoglu A. S. and Gutierrez-Ospina G. (1996) The role of the insulin-like growth factors in the central nervous system. Mol. Neurobiol. 13, 227-255.
    • (1996) Mol. Neurobiol. , vol.13 , pp. 227-255
    • D'Ercole, A.J.1    Ye, P.2    Calikoglu, A.S.3    Gutierrez-Ospina, G.4
  • 11
    • 0032967382 scopus 로고    scopus 로고
    • The role of excitotoxicity in neurodegenerative disease: Implications for therapy
    • Doble A. (1999) The role of excitotoxicity in neurodegenerative disease: implications for therapy. Pharamcol. Ther. 81, 163-221.
    • (1999) Pharamcol. Ther. , vol.81 , pp. 163-221
    • Doble, A.1
  • 12
    • 0030044324 scopus 로고    scopus 로고
    • ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis
    • Duan H., Chinnaiyan A. M., Hudson P. L., Wing J. P., He W. W. and Dixit V. M. (1996) ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis. J. Biol. Chem. 271, 1621-1625.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1621-1625
    • Duan, H.1    Chinnaiyan, A.M.2    Hudson, P.L.3    Wing, J.P.4    He, W.W.5    Dixit, V.M.6
  • 13
    • 0035927218 scopus 로고    scopus 로고
    • Distribution of ionotropic glutamate receptors subunit mRNAs in the rat hypothalamus
    • Eyigor O., Centers A. and Jennes L. (2001) Distribution of ionotropic glutamate receptors subunit mRNAs in the rat hypothalamus. J. Comp Neurol. 434, 101-124.
    • (2001) J. Comp Neurol. , vol.434 , pp. 101-124
    • Eyigor, O.1    Centers, A.2    Jennes, L.3
  • 14
    • 27644482039 scopus 로고    scopus 로고
    • Growth hormone (GH) releasing peptide-6 increase brain insulin-like growth factor (IGF-I) mRNA levels and activates Akt in RCA-6 cells as a model of neuropeptide Y neurons
    • Frago L. M., Pañeda C., Argente J. and Chowen J. A. (2005) Growth hormone (GH) releasing peptide-6 increase brain insulin-like growth factor (IGF-I) mRNA levels and activates Akt in RCA-6 cells as a model of neuropeptide Y neurons. J. Neuroendocrinol. 17, 701-710.
    • (2005) J. Neuroendocrinol. , vol.17 , pp. 701-710
    • Frago, L.M.1    Pañeda, C.2    Argente, J.3    Chowen, J.A.4
  • 15
    • 0036773551 scopus 로고    scopus 로고
    • Growth hormone (GH) and GH-Releasing peptide-6 increase brain insulin-like growth factor-I expression and activate intracellular signaling pathways involved in neuroprotection
    • Frago L. M., Pañeda C., Dickson S. I., Hewson A. K., Argente J. and Chowen J. A. (2002) Growth hormone (GH) and GH-Releasing peptide-6 increase brain insulin-like growth factor-I expression and activate intracellular signaling pathways involved in neuroprotection. Endocrinology 143, 4113-4122.
    • (2002) Endocrinology , vol.143 , pp. 4113-4122
    • Frago, L.M.1    Pañeda, C.2    Dickson, S.I.3    Hewson, A.K.4    Argente, J.5    Chowen, J.A.6
  • 16
    • 10644282148 scopus 로고    scopus 로고
    • The protein structures that shape caspase activity, specificity, activation and inhibition
    • Fuentes-Prior P. and Salvesen G. S. (2004) The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem. J. 384, 201-232.
    • (2004) Biochem. J. , vol.384 , pp. 201-232
    • Fuentes-Prior, P.1    Salvesen, G.S.2
  • 17
    • 0346494287 scopus 로고    scopus 로고
    • Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signalling
    • Garcia-Galloway E., Arango C., Pons S. and Torres-Aleman I. (2003) Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signalling. Mol. Cell Neurosci. 24, 1027-1037.
    • (2003) Mol. Cell Neurosci. , vol.24 , pp. 1027-1037
    • Garcia-Galloway, E.1    Arango, C.2    Pons, S.3    Torres-Aleman, I.4
  • 19
    • 0034995224 scopus 로고    scopus 로고
    • Glutamate receptors in peripheral tissues: Current knowledge, future research and implications for toxicology
    • Gill S. S. and Pulido O. M. (2001) Glutamate receptors in peripheral tissues: current knowledge, future research and implications for toxicology. Toxicol. Pathol. 29, 208-223.
    • (2001) Toxicol. Pathol. , vol.29 , pp. 208-223
    • Gill, S.S.1    Pulido, O.M.2
  • 20
    • 0034658288 scopus 로고    scopus 로고
    • Caspase-mediated degradation of AMPA receptor subunits: A mechanism for preventing excitotoxic necrosis and ensuring apoptosis
    • Glazner G. W., Chan S. L., Lu C. and Mattson M. P. (2000) Caspase-mediated degradation of AMPA receptor subunits: a mechanism for preventing excitotoxic necrosis and ensuring apoptosis. J. Neurosci. 20, 3641-3649.
    • (2000) J. Neurosci. , vol.20 , pp. 3641-3649
    • Glazner, G.W.1    Chan, S.L.2    Lu, C.3    Mattson, M.P.4
  • 21
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson M. D., Weil M. and Raff M. C. (1997) Programmed cell death in animal development. Cell 88, 347-354.
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 22
    • 0030741894 scopus 로고    scopus 로고
    • Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells
    • Kawasaki H., Morooka T., Shimohama S., Kimura J., Hirano T., Gotoh Y. and Nishida E. (1997) Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. J. Biol. Chem. 272, 18 518-18 521.
    • (1997) J. Biol. Chem. , vol.272 , pp. 18518-18521
    • Kawasaki, H.1    Morooka, T.2    Shimohama, S.3    Kimura, J.4    Hirano, T.5    Gotoh, Y.6    Nishida, E.7
  • 23
    • 4544235733 scopus 로고    scopus 로고
    • The mitogenic and antiapoptotic actions of ghrelin in 3T3-L1adipocytes
    • Kim M. S., Yoon C. Y. and Jang P. G. (2004) The mitogenic and antiapoptotic actions of ghrelin in 3T3-L1adipocytes. Mol. Endocrinol. 18, 2291-2301.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 2291-2301
    • Kim, M.S.1    Yoon, C.Y.2    Jang, P.G.3
  • 24
    • 0033103686 scopus 로고    scopus 로고
    • Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment
    • Knoblach S. M., Fan L. and Faden A. I. (1999) Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment. J. Neuroimmunol. 95, 115-125.
    • (1999) J. Neuroimmunol. , vol.95 , pp. 115-125
    • Knoblach, S.M.1    Fan, L.2    Faden, A.I.3
  • 25
    • 27844440193 scopus 로고    scopus 로고
    • Activation of the JNK signalling pathway: Breaking the break on apoptosis
    • Lin A. (2003) Activation of the JNK signalling pathway: breaking the break on apoptosis. Bioessays 25, 1-8.
    • (2003) Bioessays , vol.25 , pp. 1-8
    • Lin, A.1
  • 26
    • 4444289166 scopus 로고    scopus 로고
    • Ghrelin enhances the growth of cultured human adrenal zona glomerulosa cells by exerting MAPK-mediated proliferogenic and antiapoptotic effects
    • Mazzocchi G., Neri G., Ruciuski M., Rebuffat P., Spinazzi R., Malendowicz L. K. and Nussdorfer G. G. (2004) Ghrelin enhances the growth of cultured human adrenal zona glomerulosa cells by exerting MAPK-mediated proliferogenic and antiapoptotic effects. Peptides 25, 1269-1277.
    • (2004) Peptides , vol.25 , pp. 1269-1277
    • Mazzocchi, G.1    Neri, G.2    Ruciuski, M.3    Rebuffat, P.4    Spinazzi, R.5    Malendowicz, L.K.6    Nussdorfer, G.G.7
  • 27
    • 0033826339 scopus 로고    scopus 로고
    • Osmotic and glutamate receptor regulation of c-Jun NH (2)-terminal protein kinase in neuroendocrine cells
    • Meeker R. and Fernandes A. (2000) Osmotic and glutamate receptor regulation of c-Jun NH (2)-terminal protein kinase in neuroendocrine cells. Am. J. Physiol. Endocrinol. Metab. 279, 475-486.
    • (2000) Am. J. Physiol. Endocrinol. Metab. , vol.279 , pp. 475-486
    • Meeker, R.1    Fernandes, A.2
  • 28
    • 0033970158 scopus 로고    scopus 로고
    • JNK and p38 stress kinases-degenerative effectors of signal-transduction- cascades in the nervous system
    • Mielke K. and Herdegen T. (2000) JNK and p38 stress kinases-degenerative effectors of signal-transduction-cascades in the nervous system. Prog. Neurobiol. 61, 45-60.
    • (2000) Prog. Neurobiol. , vol.61 , pp. 45-60
    • Mielke, K.1    Herdegen, T.2
  • 30
    • 14844343640 scopus 로고    scopus 로고
    • Constitutive nuclear localization of activated casapase 3 in subpopulations of the astroglial family of cells
    • Noyan-Ashraf M. H., Brandizzi F. and Juurlink B. H. (2005) Constitutive nuclear localization of activated casapase 3 in subpopulations of the astroglial family of cells. Glia 49, 588-593.
    • (2005) Glia , vol.49 , pp. 588-593
    • Noyan-Ashraf, M.H.1    Brandizzi, F.2    Juurlink, B.H.3
  • 31
    • 28444464769 scopus 로고    scopus 로고
    • Non-lethal active caspase-3 expression in Bergmann glia of postnatal rat cerebellum
    • Oomman S., Strahlendorf Finckbone V. and Strahlendorf J. (2005) Non-lethal active caspase-3 expression in Bergmann glia of postnatal rat cerebellum. Dev. Brain Res. 160, 130-145.
    • (2005) Dev. Brain Res. , vol.160 , pp. 130-145
    • Oomman, S.1    Strahlendorf Finckbone, V.2    Strahlendorf, J.3
  • 32
    • 0038792224 scopus 로고    scopus 로고
    • Map kinase signalling pathways and hematologic malignancies
    • Platanias L. C. (2003) Map kinase signalling pathways and hematologic malignancies. Blood 101, 4667-4679.
    • (2003) Blood , vol.101 , pp. 4667-4679
    • Platanias, L.C.1
  • 33
    • 0037860975 scopus 로고    scopus 로고
    • JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
    • Putcha G. V., Le S., Frank S., et al. (2003) JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 38, 899-914.
    • (2003) Neuron , vol.38 , pp. 899-914
    • Putcha, G.V.1    Le, S.2    Frank, S.3
  • 34
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: Intracellular signaling by proteolysis
    • Salvesen G. S. and Dixit V. M. (1997) Caspases: intracellular signaling by proteolysis. Cell 91, 443-446.
    • (1997) Cell , vol.91 , pp. 443-446
    • Salvesen, G.S.1    Dixit, V.M.2
  • 35
    • 0034714392 scopus 로고    scopus 로고
    • Fluoro-Jade B: A high affinity fluorescent marker for the localization of neuronal degeneration
    • Schmued L. C. and Hopkins K. J. (2000) Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res. 874, 123-130.
    • (2000) Brain Res. , vol.874 , pp. 123-130
    • Schmued, L.C.1    Hopkins, K.J.2
  • 36
    • 0027234701 scopus 로고
    • The TINS/TiPS Lecture. The molecular biology of mammalian glutamate receptor channels
    • Seeburg P. H. (1993) The TINS/TiPS Lecture. The molecular biology of mammalian glutamate receptor channels. Trends Neurosci. 16, 359-365.
    • (1993) Trends Neurosci. , vol.16 , pp. 359-365
    • Seeburg, P.H.1
  • 38
    • 30944447568 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
    • Yoon S. and Seger R. (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24, 21-44.
    • (2006) Growth Factors , vol.24 , pp. 21-44
    • Yoon, S.1    Seger, R.2
  • 39
    • 0026648183 scopus 로고
    • Properties of vertebrate glutamate receptors: Calcium mobilization and desensitization
    • Zorumski C. F. and Thio L. L. (1992) Properties of vertebrate glutamate receptors: calcium mobilization and desensitization. Prog. Neurobiol. 39, 295-336.
    • (1992) Prog. Neurobiol. , vol.39 , pp. 295-336
    • Zorumski, C.F.1    Thio, L.L.2


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