Antisense inhibition of RNase P: Mechanistic aspects and application to live bacteria

Journal of Biological Chemistry

Volumn 281, Issue 41, 2006, Pages 30613-30620

  Gruegelsiepe, Heike ^a   Brandt, Ole ^b   Hartmann, Roland K ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LOCKED NUCLEIC ACID (LNA); MONOGLYCINE; PEPTIDE NUCLEIC ACID (PNA);

BACTERIA; ESCHERICHIA COLI; GROWTH KINETICS; MOLECULAR BIOLOGY; NUCLEIC ACIDS; POLYPEPTIDES;

ENZYMES;

BACTERIAL RNA; DNA; MAGNESIUM ION; OLIGONUCLEOTIDE; PEPTIDE NUCLEIC ACID; RIBONUCLEASE P;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL CELL; BACTERIAL GROWTH; CLONING; DRUG TARGETING; ENZYME INHIBITION; ESCHERICHIA COLI; IN VITRO STUDY; NONHUMAN; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SYNTHESIS;

BACILLUS SUBTILIS; BASE SEQUENCE; CATALYTIC DOMAIN; CLONING, MOLECULAR; ESCHERICHIA COLI; KINETICS; MAGNESIUM; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; RIBONUCLEASE P; RNA; RNA, CATALYTIC;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 33750040266     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603346200     Document Type: Article

References (35)

1. Frank, D. N., and Pace, N. R. (1998) Annu. Rev. Biochem. 67, 153-180
2. Dong, H., Kirsebom, L. A., and Nilsson, L. (1996) J. Mol. Biol. 261, 303-308
3. Kirsebom, L. A., and Svärd, S. G. (1994) EMBO J. 13, 4870-4876
4. Willkomm, D. K., Gruegelsiepe, H., Goudinakis, O., Kretschmer-Kazemi Far, R., Bald, R., Erdmann, V. A., and Hartmann, R. K. (2003) Chembiochem 4, 1041-1048
5. Gruegelsiepe, H., Willkomm, D. K., Goudinakis, O., and Hartmann, R. K. (2003) Chembiochem 4, 1049-1056
6. Childs, J. L., Poole, A. W., and Turner, D. H. (2003) RNA 9, 1437-1445
7. Good, L., Awasthi, S. K., Dryselius, R., Larsson, O., and Nielsen, P. E. (2001) Nat. Biotechnol. 19, 360-364
8. Kurreck, J. (2003) Eur. J. Biochem. 270, 1628-1644
9. Wahlestedt, C., Salmi, P., Good, L., Kela, J., Johnsson, T., Hökfelt, T., Broberger, C., Porreca, F., Lai, J., Ren, K., Ossipov, M., Koshkin, A., Jakobsen, N., Skouv, J., Oerum, H., Jacobsen, M. H., and Wengel, J. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 5633-5638
10. Egholm, M., Buchardt, O., Christensen, L., Behrens, C., Freier, S. M., Driver, D. A., Berg, R. H., Kim, S. K., Norden, B., and Nielsen, P. E. (1993) Nature 365, 566-568
11. Tomac, S., Sarkar, M., Ratilainen, R., Wittung, P., Nielsen, P. E., Nordén, B., and Gräslund, A. (1996) J. Am. Chem. Soc. 118, 5544-5552
12. Singh, S. K., and Wengel, J. (1998) Chem. Commun. 12, 1247-1248
13. Childs, J. L., Disney, M. D., and Turner, D. H. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 11091-11096
14. Nielsen, K. E., Rasmussen, J., Kumar, R., Wesper, J., Jacobsen, J. P., and Petersen, M. (2004) Bioconjugate Chem. 15, 449-457
15. Elayadi, A. N., Braasch, D. A., and Corey, D. R. (2002) Biochemistry 41, 9973-9981
16. Nekhotiaeva, N., Awasthi, S. K., Nielsen, P. E., and Good, L. (2004) Mol. Ther. 10, 652-659
17. Schmidt, K. S., Borkowski, S., Kurreck, J., Stephens, A. W., Bald, R., Hecht, M., Friebe, M., Dinkelborg, L., and Erdmann, V. A. (2004) Nucleic Acids Res. 19, 5757-5765
18. Brandt, O., Feldner, J., Stephan, A., Schröder, M., Schnölzer, M., Arlinghaus, H. F., Hoheisel, J. D., and Jacob, A. (2003) Nucleic Acids Res. 31, e119
19. Smith, D., Burgin, A. B., Haas, E. S., and Pace, N. R. (1992) J. Biol. Chem. 267, 2429-2436
20. Sekiguchi, M., and Iida, S. (1967) Proc. Natl. Acad. Sci. U. S. A. 58, 2316-2320
21. Hardt, W. D., Schlegl, J., Erdmann, V. A., and Hartmann, R. K. (1993) Nucleic Acids Res. 21, 3521-3527
22. Dias, N., Sénamaud-Beaufort, C., le Forestier, E., Auvin, C., Hélène, C., and Saison-Behmoaras, T. E. (2002) J. Mol. Biol. 320, 489-501
23. Geller, B. L., Deere, J. D., Stein, D. A., Kroeker, A. D., Moulton, H. M., and Iversen, P. L. (2003) Antimicrob. Agents Chemother. 47, 3233-3239
24. Rebuffat, A. G., Nawrocki, A. R., Nielsen, P. E., Bernasconi, A. G., Bernal-Mendez, E., Frey, B. M., and Frey, F. J. (2002) FASEB J. 16, 1426-1428
25. Vaara, M., and Porro, M. (1996) Antimicrob. Agents Chemother. 40, 1801-1805; Correction (1997) Antimicrob. Agents Chemother. 41, 496
26. Waugh, D. S., and Pace, N. R. (1990) J. Bacteriol. 172, 6316-6321
27. Wegscheid, B., Condon, C., and Hartmann, R. K. (2006) EMBO Rep. 7, 411-417
28. Brännvall, M., Pettersson, B. M. F., and Kirsebom, L. A. (2003) J. Mol. Biol. 325, 697-709
29. Tackett, A. J., Corey, D. R., and Raney, K. D. (2002) Nucleic Acids Res. 4, 950-957
30. Eckardt, S., Romby, P., and Sczakiel, G. (1997) Biochemistry 36, 12711-12721
31. Kolb, F. A., Engdahl, H. M., Slagter-Jager, J. G., Ehresmann, B., Ehresmann, C., Westhof, E., Wagner, E. G., and Romby, P. (2000) EMBO J. 19, 5905-5915
32. Nissen, P., Hansen, J., Ban, N., Moore, P. B., and Steitz, T. A. (2000) Science 289, 920-930
33. Zasloff, M. (2002) Nature 415, 389-395
34. Turner, J. J., Arzumanov, A. A., and Gait, M. J. (2005) Nucleic Acids Res. 1, 27-42
35. Good, L., and Nielsen, P. E. (1998) Proc. Natl. Acad. Sci. U. S. A. 5, 2073-2076