Intravenously administered oligonucleotides can be delivered to conducting airway epithelium via the bronchial circulation

Gene Therapy

Volumn 13, Issue 23, 2006, Pages 1628-1638

  Holder, E ^a,d   Griesenbach, U ^a,d   Li, S ^b   Huang, L ^c   Rogers, D F ^a   Jeffery, P K ^a   Geddes, D M ^a,d   Alton, E W F W ^a,d  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d UK Cystic Fibrosis Gene Therapy Consortium ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; CHOLESTEROL; LIPOSOME; NAKED DNA; OLIGONUCLEOTIDE; PROTAMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; BRONCHUS; CAPILLARY LEAK SYNDROME; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; CYSTIC FIBROSIS; DATA ANALYSIS; DRUG TARGETING; GENE TRANSFER; GENETIC TRANSFECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; SPUTUM; TRACHEA;

ANIMALS; BIOLOGICAL TRANSPORT; BRADYKININ; BRONCHI; CELL NUCLEUS; CYSTIC FIBROSIS; CYTOPLASM; EPITHELIAL CELLS; EXTRAVASATION OF DIAGNOSTIC AND THERAPEUTIC MATERIALS; GENE EXPRESSION; GENE THERAPY; HISTAMINE; INJECTIONS, INTRAVENOUS; LIPOSOMES; MALE; MICE; MICE, INBRED BALB C; MICROCIRCULATION; MICROSCOPY, FLUORESCENCE; NF-KAPPA B; OLIGONUCLEOTIDES; PLATELET ACTIVATING FACTOR; RESPIRATORY MUCOSA; TRANSFECTION;

ANIMALIA;

EID: 33750007183     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3302811     Document Type: Article

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