Clearance kinetics, biodistribution, and organ saturability of phosphorothioate oligodeoxynucleotides in mice

American Journal of Pathology

Volumn 149, Issue 2, 1996, Pages 717-725

  Rifai, Abdalla ^a,d   Brysch, Wolfgang ^b   Fadden, Kimberly ^a   Clark, Jeffrey ^a   Schlingensiepen, Karl Hermann ^c  

^a BROWN UNIVERSITY   (United States)

^b Biognostik ^*  (Germany)

^c MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^d RHODE ISLAND HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; BOLTON HUNTER REAGENT I 125; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; TISSUE DISTRIBUTION;

ANIMALS; AUTORADIOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; KIDNEY; KUPFFER CELLS; LIVER; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON; OLIGONUCLEOTIDES, ANTISENSE; THIONUCLEOTIDES; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 0029761186     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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