Inhibitors of Helicobacter pylori ATPase Cagα block CagA transport and cag virulence

Microbiology

Volumn 152, Issue 10, 2006, Pages 2919-2930

  Hilleringmann, Markus ^a   Pansegrau, Werner ^a   Doyle, Michael ^b   Kaufman, Susan ^b   MacKichan, Mary Lee ^b   Gianfaldoni, Claudia ^a   Ruggiero, Paolo ^a   Covacci, Antonello ^a  

^a CHIRON VACCINES   (Italy)

^b Novartis ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; CAG ALPHA ADENOSINE TRIPHOSPHATASE; CAG ALPHA ADENOSINE TRIPHOSPHATASE INHIBITOR; CAGA PROTEIN; CHIR 1; CHIR 2; CHIR 3; ENZYME INHIBITOR; INTERLEUKIN 8; UNCLASSIFIED DRUG; VIRB PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL INFECTION; BACTERIAL TRANSLOCATION; BACTERIAL VIRULENCE; CHRONIC INFLAMMATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; ENZYME ASSAY; ENZYME INHIBITION; GASTRITIS; HELICOBACTER PYLORI; HIGH THROUGHPUT SCREENING; IC 50; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STOMACH MUCOSA;

ADENOSINE TRIPHOSPHATASES; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELL LINE, TUMOR; COLONY COUNT, MICROBIAL; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; EPITHELIAL CELLS; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INTERLEUKIN-8; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; VIRULENCE;

BACTERIA (MICROORGANISMS); HELICOBACTER PYLORI;

EID: 33749593502     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.28984-0     Document Type: Article

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