The merits of testing Hardy-Weinberg equilibrium in the analysis of unmatched case-control data: A cautionary note

Annals of Human Genetics

Volumn 70, Issue 6, 2006, Pages 923-933

  Zou, Guang Yong ^a,b   Donner, Allan ^a,b  

^a WESTERN UNIVERSITY   (Canada)

^b ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

Adjusted chi square; Allelic correlation; Cochran Mantel Haenszeltest; Genotyping error; HuGE; Inbreeding coefficient; Sample size; Trend test

Indexed keywords

4 AMINOBUTYRIC ACID ALPHA SUBUNIT; 4 AMINOBUTYRIC ACID DERIVATIVE; COMPLEMENT COMPONENT C3B RECEPTOR; METHAMPHETAMINE; TRYPTOPHAN HYDROXYLASE; TRYPTOPHAN HYDROXYLASE 1; UNCLASSIFIED DRUG;

ALLELE; ANALYTICAL ERROR; ARTICLE; CASE CONTROL STUDY; CHI SQUARE TEST; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA ANALYSIS; DISEASE ASSOCIATION; DRUG ABUSE; GENETIC ASSOCIATION; GENOTYPE; HARDY WEINBERG DISTRIBUTION LAW; HUMAN; HYPOTHESIS; LINKAGE ANALYSIS; MAJOR DEPRESSION; MATHEMATICAL COMPUTING; MAXIMUM LIKELIHOOD METHOD; METHODOLOGY; MIXED ANXIETY AND DEPRESSION; PRIORITY JOURNAL; PROBABILITY; SARCOIDOSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; GENE FREQUENCY; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MODELS, STATISTICAL; SAMPLE SIZE;

EID: 33749579051     PISSN: 00034800     EISSN: 14691809     Source Type: Journal    
DOI: 10.1111/j.1469-1809.2006.00267.x     Document Type: Article

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