Positive results in association studies are associated with departure from Hardy-Weinberg equilibrium: Hint for genotyping error?

Human Genetics

Volumn 111, Issue 6, 2002, Pages 573-574

  Xu, Jianfeng ^a   Turner, Aubrey ^a   Little, Joy ^a   Bleecker, Eugene R ^a   Meyers, Deborah A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ALLELE; ANALYTICAL ERROR; CASE CONTROL STUDY; CORRELATION ANALYSIS; DNA SEQUENCE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE TECHNOLOGY; GENETIC ASSOCIATION; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; NOTE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

GENOTYPE; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 0036942338     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00439-002-0819-y     Document Type: Note

References (2)

1. Sasieni PD (1997) From genotypes to genes: Doubling the sample size. Biometrics 53:1253-1261
2. Schaid DJ, Jacobsen SJ. (1999) Biased tests of association: Comparisons fo allele frequencies when departing from Hardy-Weinberg proportions. Am J Epidemiol 149:706-711