메뉴 건너뛰기




Volumn 47, Issue SUPPL. B, 2006, Pages

Estimation of the genetic risks of exposure to ionizing radiation in humans: Current status and emerging perspectives

Author keywords

Genetic risks; Ionizing radiation

Indexed keywords

CYTOLOGY; DNA; GENE TRANSFER; GENES; MAMMALS; MOLECULAR BIOLOGY; RADIATION EFFECTS; RADIATION SHIELDING; REPAIR; RISK PERCEPTION; STEM CELLS;

EID: 33749571059     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1269/jrr.47.B57     Document Type: Review
Times cited : (28)

References (48)
  • 1
    • 0034676122 scopus 로고    scopus 로고
    • Ionizing radiation and genetic Risks. XI. The doubling dose estimates from the mid-1950s to the present and the conceptual change to the use of human data for spontaneous mutation rates and mouse data for induced mutation rates for doubling dose calculations
    • Sankaranarayanan, K. and Chakraborty, R. (2000) Ionizing radiation and genetic Risks. XI. The doubling dose estimates from the mid-1950s to the present and the conceptual change to the use of human data for spontaneous mutation rates and mouse data for induced mutation rates for doubling dose calculations. Mutat. Res. 453: 107-127.
    • (2000) Mutat. Res. , vol.453 , pp. 107-127
    • Sankaranarayanan, K.1    Chakraborty, R.2
  • 2
    • 0005537180 scopus 로고    scopus 로고
    • UNSCEAR, United Nations Scientific Committee on the Effects of Atomic Radiation. UNSCEAR 2001 Report to the General Assembly, with Scientific Annex, United Nations, New York
    • UNSCEAR, United Nations Scientific Committee on the Effects of Atomic Radiation (2001) Hereditary effects of radiation. UNSCEAR 2001 Report to the General Assembly, with Scientific Annex, United Nations, New York.
    • (2001) Hereditary Effects of Radiation
  • 3
    • 0032856296 scopus 로고    scopus 로고
    • Ionizing radiation and genetic risks. X. The potential 'phenotypes' of radiation-induced genetic damage in humans: Perspectives from human molecular biology and radiation genetics
    • Sankaranarayanan, K. (1999) Ionizing radiation and genetic risks. X. The potential 'phenotypes' of radiation-induced genetic damage in humans: perspectives from human molecular biology and radiation genetics. Mutat. Res. 429: 45-83.
    • (1999) Mutat. Res. , vol.429 , pp. 45-83
    • Sankaranarayanan, K.1
  • 4
    • 0035451068 scopus 로고    scopus 로고
    • Genomic integrity and the repair of double-strand DNA breaks
    • Pastink, A., Eeken, J. C. J. and Lohman, P. H. M. (2001) Genomic integrity and the repair of double-strand DNA breaks. Mutat. Res. 480: 37-50.
    • (2001) Mutat. Res. , vol.480 , pp. 37-50
    • Pastink, A.1    Eeken, J.C.J.2    Lohman, P.H.M.3
  • 5
    • 0035093737 scopus 로고    scopus 로고
    • DNA double-strand breaks: Signalling, repair and the cancer connection
    • Khanna, K. K. and Jackson, S. P. (2001) DNA double-strand breaks: signalling, repair and the cancer connection. Nature Genet. 27: 247-254.
    • (2001) Nature Genet. , vol.27 , pp. 247-254
    • Khanna, K.K.1    Jackson, S.P.2
  • 6
    • 0036261707 scopus 로고    scopus 로고
    • Sensing and repairing DNA double-strand breaks, Commentary
    • Jackson, S. P. (2002) Sensing and repairing DNA double-strand breaks, Commentary. Carcinogenesis 23: 687-696.
    • (2002) Carcinogenesis , vol.23 , pp. 687-696
    • Jackson, S.P.1
  • 7
  • 8
    • 0141757494 scopus 로고    scopus 로고
    • Regulation and mechanisms of mammalian double-strand break repair
    • Valerie, K. and Povirk, L. F. (2003) Regulation and mechanisms of mammalian double-strand break repair. Oncogene 22: 5792-5812.
    • (2003) Oncogene , vol.22 , pp. 5792-5812
    • Valerie, K.1    Povirk, L.F.2
  • 9
    • 0842287698 scopus 로고    scopus 로고
    • DNA double-strand break repair by homologous recombination
    • Dudáš, A. and Chovanec, M. (2004) DNA double-strand break repair by homologous recombination. Mutat. Res. 566: 131-167.
    • (2004) Mutat. Res. , vol.566 , pp. 131-167
    • Dudáš, A.1    Chovanec, M.2
  • 10
    • 33645328344 scopus 로고    scopus 로고
    • Bridge over broken ends
    • Shiloh, Y. (Guest editor)
    • Shiloh, Y. (Guest editor) (2004) Bridge over broken ends. Special Issue, DNA Repair 3: 781-1254.
    • (2004) DNA Repair , vol.3 , Issue.SPEC. ISSUE , pp. 781-1254
  • 11
    • 0344845194 scopus 로고    scopus 로고
    • Review. Pathways for mitotic homologous recombination in mammalian cells
    • Helleday, T. (2003) Review. Pathways for mitotic homologous recombination in mammalian cells. Mutat. Res. 532: 103-115.
    • (2003) Mutat. Res. , vol.532 , pp. 103-115
    • Helleday, T.1
  • 12
    • 1842763188 scopus 로고    scopus 로고
    • New insights into the mechanism of homologous recombination in yeast
    • Aylon, Y. and Kupiec, M. (2004) New insights into the mechanism of homologous recombination in yeast, Mutat. Res. 566: 231-248.
    • (2004) Mutat. Res. , vol.566 , pp. 231-248
    • Aylon, Y.1    Kupiec, M.2
  • 13
    • 0033213392 scopus 로고    scopus 로고
    • BRCA1 controls homology-directed DNA repair
    • Moynahan, M. E., Chiu, J. W., Koller, B. H. and Jasin, M. (1999) BRCA1 controls homology-directed DNA repair. Mol. Cell 4: 511-518.
    • (1999) Mol. Cell , vol.4 , pp. 511-518
    • Moynahan, M.E.1    Chiu, J.W.2    Koller, B.H.3    Jasin, M.4
  • 14
    • 0035099044 scopus 로고    scopus 로고
    • BRCA2 is required for homology-directed repair of chromosomal breaks
    • Moynahan, M. E., Pierce, A. J. and Jasin, M. (2001) BRCA2 is required for homology-directed repair of chromosomal breaks. Mol. Cell 7: 263-272.
    • (2001) Mol. Cell , vol.7 , pp. 263-272
    • Moynahan, M.E.1    Pierce, A.J.2    Jasin, M.3
  • 15
    • 0021123453 scopus 로고
    • Model for homologous recombination during transfer of DNA into mouse L cells: Role for DNA ends in the recombination process
    • Lin, F-L., Serle, K. and Sternberg, N. (1984) Model for homologous recombination during transfer of DNA into mouse L cells: role for DNA ends in the recombination process. Mol. Cell. Biol. 4: 1020-1034.
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 1020-1034
    • Lin, F.-L.1    Serle, K.2    Sternberg, N.3
  • 16
    • 0022725019 scopus 로고
    • Efficient homologous recombination of linear DNA substrates after injection into Xenopus laevis oocytes
    • Carroll, D., Wright, S. H., Wolff, R. K., Grzesiuk, E. and Maryon, E. (1986) Efficient homologous recombination of linear DNA substrates after injection into Xenopus laevis oocytes. Mol. Cell. Biol. 6: 2053-2061.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 2053-2061
    • Carroll, D.1    Wright, S.H.2    Wolff, R.K.3    Grzesiuk, E.4    Maryon, E.5
  • 17
    • 0025756169 scopus 로고
    • Characterization of recombination intermediates from DNA injected into Xenopus laevis oocytes: Evidence for a non-conservative mechanism of homologous recombination
    • Maryon, E. and Carroll, D. (1991) Characterization of recombination intermediates from DNA injected into Xenopus laevis oocytes: evidence for a non-conservative mechanism of homologous recombination, Mol. Cell Biol. 11: 3278-3287.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 3278-3287
    • Maryon, E.1    Carroll, D.2
  • 18
    • 0033946617 scopus 로고    scopus 로고
    • DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae Rad59 in double-strand break repair
    • Sugawara, N., Grzegorz, I. and Haber, J. E. (2000) DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae Rad59 in double-strand break repair. Mol. Cell. Biol. 20: 5300-5309.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5300-5309
    • Sugawara, N.1    Grzegorz, I.2    Haber, J.E.3
  • 20
    • 0029909565 scopus 로고    scopus 로고
    • A mutation in mouse rad51 results in early embryonic lethal that is suppressed by p53
    • Lim, D.-S. and Hasty, P. (1996) A mutation in mouse rad51 results in early embryonic lethal that is suppressed by p53. Mol. Cell. Biol. 16: 7133-7143.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 7133-7143
    • Lim, D.-S.1    Hasty, P.2
  • 21
    • 0030749867 scopus 로고    scopus 로고
    • Conditional gene-targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells
    • Xiao, Y. and Weaver, D. T. (1997) Conditional gene-targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells. Nucleic Acids Res. 25: 2985-2991.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2985-2991
    • Xiao, Y.1    Weaver, D.T.2
  • 22
    • 0000391880 scopus 로고    scopus 로고
    • Evidence for DNA-PK dependent and independent DNA double-strand repair pathways in mammalian cells as a function of the cell cycle
    • Lee, S. E., Mitchell, R. A., Cheng, A. and Hendrickson, E. A. (1997) Evidence for DNA-PK dependent and independent DNA double-strand repair pathways in mammalian cells as a function of the cell cycle. Mol. Cell. Biol. 17: 1425-1433.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1425-1433
    • Lee, S.E.1    Mitchell, R.A.2    Cheng, A.3    Hendrickson, E.A.4
  • 23
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and non-homologous end joining pathways of DNA double strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • Takata, M., Sasaki, M. S., Sonoda, E., Morrison, C., Hashimoto, M., Utsumi, H., Yamaguchiiwai, Y, Shinohara, A. and Takeda, S. (1998) Homologous recombination and non-homologous end joining pathways of DNA double strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J 17: 5497-5508.
    • (1998) EMBO J , vol.17 , pp. 5497-5508
    • Takata, M.1    Sasaki, M.S.2    Sonoda, E.3    Morrison, C.4    Hashimoto, M.5    Utsumi, H.6    Yamaguchiiwai, Y.7    Shinohara, A.8    Takeda, S.9
  • 24
    • 0042632901 scopus 로고    scopus 로고
    • Pathways of DNA double-strand break repair during the mammalian cell cycle
    • Rothkamm, K., Krüger, I., Thompson, L. H. and Löbrich, M. (2003) Pathways of DNA double-strand break repair during the mammalian cell cycle, Mol. Cell. Biol. 23: 5706-5715.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5706-5715
    • Rothkamm, K.1    Krüger, I.2    Thompson, L.H.3    Löbrich, M.4
  • 25
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • IHGSC, International Human Genome Sequencing Consortium
    • IHGSC, International Human Genome Sequencing Consortium (2001) Initial sequencing and analysis of the human genome. Nature 409: 860-921.
    • (2001) Nature , vol.409 , pp. 860-921
  • 26
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • IHGSC, International Human Genome Sequencing Consortium
    • IHGSC, International Human Genome Sequencing Consortium (2004) Finishing the euchromatic sequence of the human genome. Nature 431: 931-945.
    • (2004) Nature , vol.431 , pp. 931-945
  • 27
    • 0036245495 scopus 로고    scopus 로고
    • Segmental duplications and the evolution of the primate genome
    • Samonte, R.V. and Eichler, E. E. (2002) Segmental duplications and the evolution of the primate genome. Nature Rev. Genet. 3: 65-72.
    • (2002) Nature Rev. Genet. , vol.3 , pp. 65-72
    • Samonte, R.V.1    Eichler, E.E.2
  • 28
    • 0034028921 scopus 로고    scopus 로고
    • Structure of chromosomal duplicons and their role in mediating human genomic disorders
    • Ji, Y., Eichler, E. E., Schwartz, S. and Nicholls, R. D. (2000) Structure of chromosomal duplicons and their role in mediating human genomic disorders. Genome Res. 10: 597-610.
    • (2000) Genome Res. , vol.10 , pp. 597-610
    • Ji, Y.1    Eichler, E.E.2    Schwartz, S.3    Nicholls, R.D.4
  • 29
    • 0034831138 scopus 로고    scopus 로고
    • Segmental duplications: Organization and impact within the current human genome project assembly
    • Bailey, J. A., Yavor, A. M., Massa, H. F., Trask, B. J. and Eichler, E. E. (2001) Segmental duplications: organization and impact within the current human genome project assembly. Genome Res. 11:1005-1017.
    • (2001) Genome Res. , vol.11 , pp. 1005-1017
    • Bailey, J.A.1    Yavor, A.M.2    Massa, H.F.3    Trask, B.J.4    Eichler, E.E.5
  • 30
    • 0035487212 scopus 로고    scopus 로고
    • Segmental duplications: An expanding role in genomic instability and disease
    • Emanuel, B. S. and Shaikh, T. H. (2001) Segmental duplications: an expanding role in genomic instability and disease. Nature Rev. Genet. 2: 791-800.
    • (2001) Nature Rev. Genet. , vol.2 , pp. 791-800
    • Emanuel, B.S.1    Shaikh, T.H.2
  • 31
    • 0031731487 scopus 로고    scopus 로고
    • Genomic disorders: Structural features of the genome can lead to DNA rearrangements and human disease traits
    • Lupski, J. R. (1998) Genomic disorders: structural features of the genome can lead to DNA rearrangements and human disease traits. Trends Genet. 14: 417-422.
    • (1998) Trends Genet. , vol.14 , pp. 417-422
    • Lupski, J.R.1
  • 33
    • 0037837485 scopus 로고    scopus 로고
    • Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence
    • Cheung, J., Estivill, X., Khaja, R., MacDonald, J. R., Lau, K., Tsui, L-C. and Scherer, S. W. (2003) Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence. Genome Biol. 4: R25.
    • (2003) Genome Biol. , vol.4
    • Cheung, J.1    Estivill, X.2    Khaja, R.3    MacDonald, J.R.4    Lau, K.5    Tsui, L.-C.6    Scherer, S.W.7
  • 34
    • 0036468807 scopus 로고    scopus 로고
    • Genome architecture, rearrangements and genomic disorders
    • Stankiewicz, P. and Lupski, J. R. (2002) Genome architecture, rearrangements and genomic disorders. Trends Genet. 18: 74-82.
    • (2002) Trends Genet. , vol.18 , pp. 74-82
    • Stankiewicz, P.1    Lupski, J.R.2
  • 35
    • 0032695458 scopus 로고    scopus 로고
    • Homologous DNA exchanges in humans can be explained by the yeast double-strand break repair model: A study of 17p11.2 rearrangement associated with CMT1A and HNPP 1
    • Lopes, J., Tardieu, S., Silander, K., Blair, I., Vandenberghe, A., Palau, F., Ruberg, M., Brice, A. and LeGuern, E. (1999) Homologous DNA exchanges in humans can be explained by the yeast double-strand break repair model: a study of 17p11.2 rearrangement associated with CMT1A and HNPP 1. Hum. Mol. Genet. 8: 2285-2292.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 2285-2292
    • Lopes, J.1    Tardieu, S.2    Silander, K.3    Blair, I.4    Vandenberghe, A.5    Palau, F.6    Ruberg, M.7    Brice, A.8    Leguern, E.9
  • 36
    • 0034513406 scopus 로고    scopus 로고
    • Molecular mechanisms for constitutional chromosomal rearrangements in humans
    • Shaffer, L. G. and Lupski, J. R. (2000) Molecular mechanisms for constitutional chromosomal rearrangements in humans. Ann. Rev. Genet. 34: 297-329.
    • (2000) Ann. Rev. Genet. , vol.34 , pp. 297-329
    • Shaffer, L.G.1    Lupski, J.R.2
  • 37
    • 1842526843 scopus 로고    scopus 로고
    • Implications of human genome architecture for rearrangement-based disorders the genomic basis of disease
    • [Review]
    • Shaw, C. J. and Lupski, J. R. (2004) Implications of human genome architecture for rearrangement-based disorders the genomic basis of disease. Hum. Mol. Genet. 13: [Review] R57-R64.
    • (2004) Hum. Mol. Genet. , vol.13
    • Shaw, C.J.1    Lupski, J.R.2
  • 39
    • 0033759490 scopus 로고    scopus 로고
    • Nov-Dec All you want to know about spermatogonia but were afraid to ask
    • de Rooij, D. G. and Russell, L. D. (2000 Nov-Dec) All you want to know about spermatogonia but were afraid to ask. J. Androl. 776-798.
    • (2000) J. Androl. , pp. 776-798
    • De Rooij, D.G.1    Russell, L.D.2
  • 40
    • 0001387585 scopus 로고
    • Spermatogenesis in man: An estimate of its duration
    • Heller, C. G. and Clermont, Y. (1963) Spermatogenesis in man: an estimate of its duration. Science 140: 184-185.
    • (1963) Science , vol.140 , pp. 184-185
    • Heller, C.G.1    Clermont, Y.2
  • 41
    • 0013889216 scopus 로고
    • Renewal of spermatogonia in man
    • Clermont, Y. (1966) Renewal of spermatogonia in man, Am.J. Anat. 118: 509-524.
    • (1966) Am.J. Anat. , vol.118 , pp. 509-524
    • Clermont, Y.1
  • 42
    • 0026717551 scopus 로고
    • The sensitivity of quiescent and proliferating mouse spermatogonial stem cells to X-irradiation
    • van der Meer, Y., Huiskamp, B. M. R., Davids, J. A. G., van der Tweel, I. and de Rooij, D. G. (1992) The sensitivity of quiescent and proliferating mouse spermatogonial stem cells to X-irradiation. Radiat. Res. 130: 289-295.
    • (1992) Radiat. Res. , vol.130 , pp. 289-295
    • Van Der Meer, Y.1    Huiskamp, B.M.R.2    Davids, J.A.G.3    Van Der Tweel, I.4    De Rooij, D.G.5
  • 43
    • 0026643406 scopus 로고
    • The sensitivity to X-rays of mouse spermatogonia that are committed to differentiate and of differentiating spermatogonia
    • van der Meer, Y., Huiskamp, B. M. R., Davids, J. A. G., van der Tweel, I. and de Rooij, D. G. (1992) The sensitivity to X-rays of mouse spermatogonia that are committed to differentiate and of differentiating spermatogonia. Radiat. Res. 296: 296-302.
    • (1992) Radiat. Res. , vol.296 , pp. 296-302
    • Van Der Meer, Y.1    Huiskamp, B.M.R.2    Davids, J.A.G.3    Van Der Tweel, I.4    De Rooij, D.G.5
  • 45
    • 0014992169 scopus 로고
    • Comparative aspects of the effects of radiation during oogenesis
    • Baker, T. G. (1971) Comparative aspects of the effects of radiation during oogenesis, Mutat. Res. 11: 9-22.
    • (1971) Mutat. Res. , vol.11 , pp. 9-22
    • Baker, T.G.1
  • 47
    • 0033361899 scopus 로고    scopus 로고
    • A chromosomal duplication map of malformations: Regions of suspected haplo- and triplolethality and tolerance of segmental aneuploidy in humans
    • Brewer, C., Holloway, S., Zawalnyski, P., Schinzel, A. and Fitzpatrick, D. (1999) A chromosomal duplication map of malformations: regions of suspected haplo- and triplolethality and tolerance of segmental aneuploidy in humans, Am. J. Hum. Genet. 64: 1702-1708.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 1702-1708
    • Brewer, C.1    Holloway, S.2    Zawalnyski, P.3    Schinzel, A.4    Fitzpatrick, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.