-
1
-
-
33744982042
-
AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update: Endorsed by the National Heart, Lung, and Blood Institute
-
AHA/ACC; National Heart, Lung and Blood Institute
-
Smith SC Jr, Allen J, Blair SN, Bonow RO, Brass LM, Fonarow GC, Grundy SM, Hiratzka L, Jones D, Krumholz HM, Mosca L, Pasternak RC, Pearson T, Pfeffer MA, Taubert KA, AHA/ACC; National Heart, Lung and Blood Institute: AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update: endorsed by the National Heart, Lung, and Blood Institute. Circulation 2006, 113:2363-2372.
-
(2006)
Circulation
, vol.113
, pp. 2363-2372
-
-
Smith Jr., S.C.1
Allen, J.2
Blair, S.N.3
Bonow, R.O.4
Brass, L.M.5
Fonarow, G.C.6
Grundy, S.M.7
Hiratzka, L.8
Jones, D.9
Krumholz, H.M.10
Mosca, L.11
Pasternak, R.C.12
Pearson, T.13
Pfeffer, M.A.14
Taubert, K.A.15
-
2
-
-
11144355354
-
Intensive versus moderate lipid lowering with statins after acute coronary syndromes
-
Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 Investigators
-
Cannon CP, Braunwald E, McCabe CH, Rader DJ, Rouleau JL, Belder R, Joyal SV, Hill KA, Pfeffer MA, Skene AM: Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 Investigators. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med 2004, 350:1495-504.
-
(2004)
N Engl J Med
, vol.350
, pp. 1495-1504
-
-
Cannon, C.P.1
Braunwald, E.2
McCabe, C.H.3
Rader, D.J.4
Rouleau, J.L.5
Belder, R.6
Joyal, S.V.7
Hill, K.A.8
Pfeffer, M.A.9
Skene, A.M.10
-
3
-
-
4544243333
-
Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: Phase Z of the A to Z trial
-
A to Z Investigators
-
de Lemos JA, Blazing MA, Wiviott SD, Lewis EF, Fox KA, White HD, Rouleau JL, Pedersen TR, Gardner LH, Mukherjee R, Ramsey KE, Palmisano J, Bilheimer DW, Pfeffer MA, Califf RM, Braunwald E, A to Z Investigators: Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: phase Z of the A to Z trial. JAMA 2004, 292:1307-1316.
-
(2004)
JAMA
, vol.292
, pp. 1307-1316
-
-
de Lemos, J.A.1
Blazing, M.A.2
Wiviott, S.D.3
Lewis, E.F.4
Fox, K.A.5
White, H.D.6
Rouleau, J.L.7
Pedersen, T.R.8
Gardner, L.H.9
Mukherjee, R.10
Ramsey, K.E.11
Palmisano, J.12
Bilheimer, D.W.13
Pfeffer, M.A.14
Califf, R.M.15
Braunwald, E.16
-
4
-
-
15944410609
-
Intensive lipid lowering with atorvastatin in patients with stable coronary disease
-
Treating to New Targets (TNT) Investigators
-
LaRosa JC, Grundy SM, Waters DD, Shear C, Barter P, Fruchart JC, Gotto AM, Greten H, Kastelein JJ, Shepherd J, Wenger NK, Treating to New Targets (TNT) Investigators: Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 2005, 352:1425-1435.
-
(2005)
N Engl J Med
, vol.352
, pp. 1425-1435
-
-
LaRosa, J.C.1
Grundy, S.M.2
Waters, D.D.3
Shear, C.4
Barter, P.5
Fruchart, J.C.6
Gotto, A.M.7
Greten, H.8
Kastelein, J.J.9
Shepherd, J.10
Wenger, N.K.11
-
5
-
-
27744603499
-
High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: The IDEAL study: A randomized controlled trial
-
Incremental Decrease in End Points Through Aggressive Lipid Lowering (IDEAL) Study Group
-
Pedersen TR, Faergeman O, Kastelein JJ, Olsson AG, Tikkanen MJ, Holme I, Larsen ML, Bendiksen FS, Lindahl C, Szarek M, Tsai J: Incremental Decrease in End Points Through Aggressive Lipid Lowering (IDEAL) Study Group. High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a randomized controlled trial. JAMA 2005, 294:2437-2445.
-
(2005)
JAMA
, vol.294
, pp. 2437-2445
-
-
Pedersen, T.R.1
Faergeman, O.2
Kastelein, J.J.3
Olsson, A.G.4
Tikkanen, M.J.5
Holme, I.6
Larsen, M.L.7
Bendiksen, F.S.8
Lindahl, C.9
Szarek, M.10
Tsai, J.11
-
6
-
-
26844580066
-
Statins research unfinished saga: Desirability versus feasibility
-
Fisman EZ, Adler Y, Tenenbaum A: Statins research unfinished saga: desirability versus feasibility. Cardiovasc Diabetol 2005, 41:8.
-
(2005)
Cardiovasc Diabetol
, vol.41
, pp. 8
-
-
Fisman, E.Z.1
Adler, Y.2
Tenenbaum, A.3
-
7
-
-
27744464471
-
The IDEAL cholesterol: Lower is better
-
Christopher CP: The IDEAL cholesterol: lower is better. JAMA 2005, 294:2492-2494.
-
(2005)
JAMA
, vol.294
, pp. 2492-2494
-
-
Christopher, C.P.1
-
8
-
-
15944394012
-
Low-density lipoprotein cholesterol in patients with stable coronary heart disease - Is it time to shift our goals?
-
Pitt B: Low-density lipoprotein cholesterol in patients with stable coronary heart disease - is it time to shift our goals? N Engl J Med 2005, 352:1483-1484.
-
(2005)
N Engl J Med
, vol.352
, pp. 1483-1484
-
-
Pitt, B.1
-
9
-
-
13144290929
-
Which is the best lipid-modifying strategy in metabolic syndrome and diabetes: Fibrates, statins or both?
-
Tenenbaum A, Fisman EZ: Which is the best lipid-modifying strategy in metabolic syndrome and diabetes: fibrates, statins or both? Cardiovasc Diabetol 2004, 3:10.
-
(2004)
Cardiovasc Diabetol
, vol.3
, pp. 10
-
-
Tenenbaum, A.1
Fisman, E.Z.2
-
10
-
-
0037099364
-
The role of high-density lipoprotein [HDL] cholesterol in the prevention and treatment of coronary heart disease: Expert Group recommendations
-
for the Expert Group on HDL Cholesterol
-
Sacks FM, for the Expert Group on HDL Cholesterol: The role of high-density lipoprotein [HDL] cholesterol in the prevention and treatment of coronary heart disease: Expert Group recommendations. Am J Cardiol 2002, 90:139-143.
-
(2002)
Am J Cardiol
, vol.90
, pp. 139-143
-
-
Sacks, F.M.1
-
11
-
-
0035924635
-
Peroxisome proliferator-activated receptor-alpha activation and high-density lipoprotein metabolism
-
Fruchart JC: Peroxisome proliferator-activated receptor-alpha activation and high-density lipoprotein metabolism. Am J Cardiol 2001, 88(12A):24N-29N.
-
(2001)
Am J Cardiol
, vol.88
, Issue.12 A
-
-
Fruchart, J.C.1
-
12
-
-
1842454746
-
Clinical interest of PPARs ligands
-
Verges B: Clinical interest of PPARs ligands. Diabetes Metab 2004, 30:7-12.
-
(2004)
Diabetes Metab
, vol.30
, pp. 7-12
-
-
Verges, B.1
-
13
-
-
0023232216
-
Helsinki Heart Study: Primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease
-
Frick MH, Elo O, Haapa K, Heinonen OP, Heinsalmi P, Helo P, Huttunen JK, Kaitaniemi P, Koskinen P, Manninen V: Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med 1987, 317:1237-1245.
-
(1987)
N Engl J Med
, vol.317
, pp. 1237-1245
-
-
Frick, M.H.1
Elo, O.2
Haapa, K.3
Heinonen, O.P.4
Heinsalmi, P.5
Helo, P.6
Huttunen, J.K.7
Kaitaniemi, P.8
Koskinen, P.9
Manninen, V.10
-
14
-
-
0033527030
-
Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol
-
Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
-
Rubins HB, Robins SJ, Collins D, Fye CL, Anderson JW, Elam MB, Faas FH, Linares E, Schaefer EJ, Schectman G, Wilt TJ, Wittes J: Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N Engl J Med 1999, 341:410-418.
-
(1999)
N Engl J Med
, vol.341
, pp. 410-418
-
-
Rubins, H.B.1
Robins, S.J.2
Collins, D.3
Fye, C.L.4
Anderson, J.W.5
Elam, M.B.6
Faas, F.H.7
Linares, E.8
Schaefer, E.J.9
Schectman, G.10
Wilt, T.J.11
Wittes, J.12
-
15
-
-
0030665041
-
Effect of bezafibrate treatment over five years on coronary plaques causing 20% to 50% diameter narrowing (The Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT))
-
Ericsson CG, Nilsson J, Grip L, Svane B, Hamsten A: Effect of bezafibrate treatment over five years on coronary plaques causing 20% to 50% diameter narrowing (The Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT)). Am J Cardiol 1997, 8:1125-1129.
-
(1997)
Am J Cardiol
, vol.8
, pp. 1125-1129
-
-
Ericsson, C.G.1
Nilsson, J.2
Grip, L.3
Svane, B.4
Hamsten, A.5
-
16
-
-
0031922041
-
Cardiovascular outcomes in type 2 diabetes. A double-blind placebo-controlled study of bezafibrate: The St. Mary's, Ealing, Northwick Park Diabetes Cardiovascular Disease Prevention (SENDCAP) Study
-
Elkeles RS, Diamond JR, Poulter C, Dhanjil S, Nicolaides AN, Mahmood S, Richmond W, Mather H, Sharp P, Feher MD: Cardiovascular outcomes in type 2 diabetes. A double-blind placebo-controlled study of bezafibrate: the St. Mary's, Ealing, Northwick Park Diabetes Cardiovascular Disease Prevention (SENDCAP) Study. Diabetes Care 1998, 21:641-648.
-
(1998)
Diabetes Care
, vol.21
, pp. 641-648
-
-
Elkeles, R.S.1
Diamond, J.R.2
Poulter, C.3
Dhanjil, S.4
Nicolaides, A.N.5
Mahmood, S.6
Richmond, W.7
Mather, H.8
Sharp, P.9
Feher, M.D.10
-
17
-
-
0037121346
-
Bezafibrate in men with lower extremity arterial disease: Randomised controlled trial
-
Meade T, Zuhrie R, Cook C, Cooper J: Bezafibrate in men with lower extremity arterial disease: randomised controlled trial. BMJ 2002, 325(7373):1139.
-
(2002)
BMJ
, vol.325
, Issue.7373
, pp. 1139
-
-
Meade, T.1
Zuhrie, R.2
Cook, C.3
Cooper, J.4
-
18
-
-
0034604225
-
Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: The Bezafibrate Infarction Prevention (BIP) study
-
Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: the Bezafibrate Infarction Prevention (BIP) study. Circulation 2000, 102:21-27.
-
(2000)
Circulation
, vol.102
, pp. 21-27
-
-
-
19
-
-
0035941990
-
Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: The diabetes atherosclerosis intervention study, a randomised study
-
Diabetes Atherosclerosis Intervention Study Investigators
-
Diabetes Atherosclerosis Intervention Study Investigators: Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: the diabetes atherosclerosis intervention study, a randomised study. Lancet 2001, 357:905-910.
-
(2001)
Lancet
, vol.357
, pp. 905-910
-
-
-
20
-
-
19344375593
-
Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome
-
Tenenbaum A, Motro M, Fisman EZ, Tanne D, Boyko V, Behar S: Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome. Arch Intern Med 2005, 165:1154-1160.
-
(2005)
Arch Intern Med
, vol.165
, pp. 1154-1160
-
-
Tenenbaum, A.1
Motro, M.2
Fisman, E.Z.3
Tanne, D.4
Boyko, V.5
Behar, S.6
-
21
-
-
0026597808
-
Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment
-
Manninen V, Tenkanen L, Koskinen P, Huttunen JK, Manttari M, Heinonen OP, Frick MH: Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment. Circulation 1992, 85:37-45.
-
(1992)
Circulation
, vol.85
, pp. 37-45
-
-
Manninen, V.1
Tenkanen, L.2
Koskinen, P.3
Huttunen, J.K.4
Manttari, M.5
Heinonen, O.P.6
Frick, M.H.7
-
22
-
-
0037049366
-
Diabetes, plasma insulin, and cardiovascular disease: Subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT)
-
Rubins HB, Robins SJ, Collins D, Nelson DB, Elam MB, Schaefer EJ, Faas FH, Anderson JW: Diabetes, plasma insulin, and cardiovascular disease: subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT). Arch Intern Med 2002, 162:2597-2604.
-
(2002)
Arch Intern Med
, vol.162
, pp. 2597-2604
-
-
Rubins, H.B.1
Robins, S.J.2
Collins, D.3
Nelson, D.B.4
Elam, M.B.5
Schaefer, E.J.6
Faas, F.H.7
Anderson, J.W.8
-
23
-
-
33645729392
-
Gemfibrozil in the treatment of dyslipidemia: An 18-year mortality follow-up of the Helsinki Heart Study
-
Tenkanen L, Manttari M, Kovanen P, Virkkunen H, Manninen V: Gemfibrozil in the treatment of dyslipidemia: an 18-year mortality follow-up of the Helsinki Heart Study. Arch Intern Med 2006, 166:743-748.
-
(2006)
Arch Intern Med
, vol.166
, pp. 743-748
-
-
Tenkanen, L.1
Manttari, M.2
Kovanen, P.3
Virkkunen, H.4
Manninen, V.5
-
24
-
-
28044452217
-
Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): Randomised controlled trial
-
FIELD study investigators
-
Keech A, Simes RJ, Barter P, Best J, Scott R, Taskinen MR, Forder P, Pillai A, Davis T, Glasziou P, Drury P, Kesaniemi YA, Sullivan D, Hunt D, Colman P, d'Emden M, Whiting M, Ehnholm C, Laakso M, FIELD study investigators: Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet 2005, 366:1849-1861.
-
(2005)
Lancet
, vol.366
, pp. 1849-1861
-
-
Keech, A.1
Simes, R.J.2
Barter, P.3
Best, J.4
Scott, R.5
Taskinen, M.R.6
Forder, P.7
Pillai, A.8
Davis, T.9
Glasziou, P.10
Drury, P.11
Kesaniemi, Y.A.12
Sullivan, D.13
Hunt, D.14
Colman, P.15
d'Emden, M.16
Whiting, M.17
Ehnholm, C.18
Laakso, M.19
-
25
-
-
0033998334
-
The PPARs: From orphan receptors to drug discovery
-
Willson TM, Brown PJ, Sternbach DD, Henke BR: The PPARs: from orphan receptors to drug discovery. J Med Chem 2000, 43:527-550.
-
(2000)
J Med Chem
, vol.43
, pp. 527-550
-
-
Willson, T.M.1
Brown, P.J.2
Sternbach, D.D.3
Henke, B.R.4
-
26
-
-
0036183630
-
The mechanisms of action of PPARs
-
Berger J, Moller DE: The mechanisms of action of PPARs. Annu Rev Med 2002, 53:409-435.
-
(2002)
Annu Rev Med
, vol.53
, pp. 409-435
-
-
Berger, J.1
Moller, D.E.2
-
27
-
-
26844431513
-
Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: The bezafibrate lessons
-
Tenenbaum A, Motro M, Fisman EZ: Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons. Cardiovasc Diabetol 2005, 4:14.
-
(2005)
Cardiovasc Diabetol
, vol.4
, pp. 14
-
-
Tenenbaum, A.1
Motro, M.2
Fisman, E.Z.3
-
28
-
-
33645738300
-
Attenuation of progression of insulin resistance in patients with coronary artery disease by bezafibrate
-
Tenenbaum A, Fisman EZ, Boyko V, Benderly M, Tanne D, Haim M, Matas Z, Motro M, Behar S: Attenuation of progression of insulin resistance in patients with coronary artery disease by bezafibrate. Arch Intern Med 2006, 166:737-741.
-
(2006)
Arch Intern Med
, vol.166
, pp. 737-741
-
-
Tenenbaum, A.1
Fisman, E.Z.2
Boyko, V.3
Benderly, M.4
Tanne, D.5
Haim, M.6
Matas, Z.7
Motro, M.8
Behar, S.9
-
29
-
-
2442660528
-
Peroxisome proliferator-activated receptors ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease
-
Tenenbaum A, Motro M, Fisman EZ, Schwammenthal E, Adler Y, Goldenberg I, Leor J, Boyko V, Mandelzweig L, Behar S: Peroxisome proliferator-activated receptors ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease. Circulation 2004, 109:2197-2202.
-
(2004)
Circulation
, vol.109
, pp. 2197-2202
-
-
Tenenbaum, A.1
Motro, M.2
Fisman, E.Z.3
Schwammenthal, E.4
Adler, Y.5
Goldenberg, I.6
Leor, J.7
Boyko, V.8
Mandelzweig, L.9
Behar, S.10
-
30
-
-
26444604923
-
Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients
-
Tenenbaum A, Motro M, Fisman EZ, Adler Y, Shemesh J, Tanne D, Leor J, Boyko V, Schwammenthal E, Behar S: Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients. Eur Heart J 2005, 26:2032-2038.
-
(2005)
Eur Heart J
, vol.26
, pp. 2032-2038
-
-
Tenenbaum, A.1
Motro, M.2
Fisman, E.Z.3
Adler, Y.4
Shemesh, J.5
Tanne, D.6
Leor, J.7
Boyko, V.8
Schwammenthal, E.9
Behar, S.10
-
31
-
-
33645746101
-
The role of fibrates in a statin world
-
Bloomfield HE: The role of fibrates in a statin world. Arch Intern Med 2006, 166:715-716.
-
(2006)
Arch Intern Med
, vol.166
, pp. 715-716
-
-
Bloomfield, H.E.1
-
32
-
-
0000454838
-
Insulin resistance: The fundamental trigger of type 2 diabetes
-
Groop LC: Insulin resistance: the fundamental trigger of type 2 diabetes. Diabetes Obes Metab 1999:S1-S7.
-
(1999)
Diabetes Obes Metab
-
-
Groop, L.C.1
-
33
-
-
2442671417
-
Metabolic syndrome and type 2 diabetes mellitus: Focus on peroxisome proliferator activated receptors (PPAR)
-
Tenenbaum A, Fisman EZ, Motro M: Metabolic syndrome and type 2 diabetes mellitus: focus on peroxisome proliferator activated receptors (PPAR). Cardiovasc Diabetol 2003, 2:4.
-
(2003)
Cardiovasc Diabetol
, vol.2
, pp. 4
-
-
Tenenbaum, A.1
Fisman, E.Z.2
Motro, M.3
-
34
-
-
0037021505
-
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
-
Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J. Salonen JT: The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 2002, 288:2709-2716.
-
(2002)
JAMA
, vol.288
, pp. 2709-2716
-
-
Lakka, H.M.1
Laaksonen, D.E.2
Lakka, T.A.3
Niskanen, L.K.4
Kumpusalo, E.5
Tuomilehto, J.6
Salonen, J.T.7
-
36
-
-
0026608876
-
Effects of slow release bezafibrate on the lipid pattern and on blood glucose of type 2 diabetic patients with hyperlipidaemia
-
Rovellini A, Sommariva D, Branchi A, Maraffi F, Montalto C, Gandini R, Fasoli A: Effects of slow release bezafibrate on the lipid pattern and on blood glucose of type 2 diabetic patients with hyperlipidaemia. Pharmacol Res 1992, 25:237-245.
-
(1992)
Pharmacol Res
, vol.25
, pp. 237-245
-
-
Rovellini, A.1
Sommariva, D.2
Branchi, A.3
Maraffi, F.4
Montalto, C.5
Gandini, R.6
Fasoli, A.7
-
37
-
-
0035048276
-
Effects of bezafibrate on insulin sensitivity and insulin secretion in non-obese Japanese type 2 diabetic patients
-
Taniguchi A, Fukushima M, Sakai M, Tokuyama K, Nagata I, Fukunaga A, Kishimoto H, Doi K, Yamashita Y, Matsuura T, Kitatani N,Ckumura T, Nagasaka S, Nakaishi S, Nakai Y: Effects of bezafibrate on insulin sensitivity and insulin secretion in non-obese Japanese type 2 diabetic patients. Metabolism 2001, 50:477-480.
-
(2001)
Metabolism
, vol.50
, pp. 477-480
-
-
Taniguchi, A.1
Fukushima, M.2
Sakai, M.3
Tokuyama, K.4
Nagata, I.5
Fukunaga, A.6
Kishimoto, H.7
Doi, K.8
Yamashita, Y.9
Matsuura, T.10
Kitatani, N.11
Ckumura, T.12
Nagasaka, S.13
Nakaishi, S.14
Nakai, Y.15
-
38
-
-
0036121471
-
Severe hypertriglyceridemia with insulin resistance is associated with systemic inflammation: Reversal with bezafibrate therapy in a randomized controlled trial
-
Jonkers IJ, Mohrschladt MF, Westendorp RG, van der Laarse A, Smelt AH: Severe hypertriglyceridemia with insulin resistance is associated with systemic inflammation: reversal with bezafibrate therapy in a randomized controlled trial. Am J Med 2002, 112:275-280.
-
(2002)
Am J Med
, vol.112
, pp. 275-280
-
-
Jonkers, I.J.1
Mohrschladt, M.F.2
Westendorp, R.G.3
van der Laarse, A.4
Smelt, A.H.5
-
39
-
-
0025151893
-
Lowering of plasma glucose concentrations with bezafibrate in patients with moderately controlled NIDDM
-
Jones IR, Swai A, Taylor R, Miller M, Laker MF, Alberti KG: Lowering of plasma glucose concentrations with bezafibrate in patients with moderately controlled NIDDM. Diabetes Care 1990, 13:855-863.
-
(1990)
Diabetes Care
, vol.13
, pp. 855-863
-
-
Jones, I.R.1
Swai, A.2
Taylor, R.3
Miller, M.4
Laker, M.F.5
Alberti, K.G.6
-
40
-
-
6044233001
-
Role of fibric Acid derivatives in the management of risk factors for coronary heart disease
-
Despres JP, Lemieux I, Robins SJ: Role of fibric Acid derivatives in the management of risk factors for coronary heart disease. Drugs 2004, 64:2177-2198.
-
(2004)
Drugs
, vol.64
, pp. 2177-2198
-
-
Despres, J.P.1
Lemieux, I.2
Robins, S.J.3
-
41
-
-
0031442321
-
Niacin decreases removal of high-density lipoprotein apolipoprotein A-1 but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transport
-
Jin FY, Kamanna VS, Kashyap, ML: Niacin decreases removal of high-density lipoprotein apolipoprotein A-1 but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transport. Arterioscler Thromb Vasc Biol 1997, 17:2020-2028.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 2020-2028
-
-
Jin, F.Y.1
Kamanna, V.S.2
Kashyap, M.L.3
-
42
-
-
16644369497
-
Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells
-
Ganji SH, Tavintharan S, Zhu D, Xing Y, Kamanna VS, Kashyap ML: Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells. J Lipid Res 2004, 45:1835-1845.
-
(2004)
J Lipid Res
, vol.45
, pp. 1835-1845
-
-
Ganji, S.H.1
Tavintharan, S.2
Zhu, D.3
Xing, Y.4
Kamanna, V.S.5
Kashyap, M.L.6
-
43
-
-
0037352280
-
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
-
Tunaru S, Kero J, Schaub A, Wufka C, Blaukat A, Pfeffer K, Offermanns S: PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect. Nat Med 2003, 9:352-355.
-
(2003)
Nat Med
, vol.9
, pp. 352-355
-
-
Tunaru, S.1
Kero, J.2
Schaub, A.3
Wufka, C.4
Blaukat, A.5
Pfeffer, K.6
Offermanns, S.7
-
44
-
-
0015593704
-
The Coronary Drug Project: Design, Methods, and Baseline Results
-
The Coronary Drug Project Research Group
-
The Coronary Drug Project Research Group: The Coronary Drug Project: Design, Methods, and Baseline Results. Circulation 1973, 47:1-50.
-
(1973)
Circulation
, vol.47
, pp. 1-50
-
-
-
45
-
-
31944438344
-
Benefits of niacin in patients with versus without the metabolic syndrome and healed myocardial infarction (from the Coronary Drug Project)
-
Canner PL, Furberg CD, McGovern ME: Benefits of niacin in patients with versus without the metabolic syndrome and healed myocardial infarction (from the Coronary Drug Project). Am J Cardiol 2006, 97:477-479.
-
(2006)
Am J Cardiol
, vol.97
, pp. 477-479
-
-
Canner, P.L.1
Furberg, C.D.2
McGovern, M.E.3
-
46
-
-
11844296800
-
Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: A meta-analysis of randomized controlled trials
-
Birjmohun RS, Hutten BA, Kastelein JJ, Stroes ES: Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials. J Am Coll Cardiol 2005, 45:185-197.
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 185-197
-
-
Birjmohun, R.S.1
Hutten, B.A.2
Kastelein, J.J.3
Stroes, E.S.4
-
47
-
-
33747242010
-
The role of high-density lipoprotein cholesterol in the prevention and possible treatment of cardiovascular diseases
-
Choi BG, Vilahur G, Yadegar D, Viles-Gonzalez JF, Badimon JJ: The role of high-density lipoprotein cholesterol in the prevention and possible treatment of cardiovascular diseases. Curr Mol Med 2006, 6:571-587.
-
(2006)
Curr Mol Med
, vol.6
, pp. 571-587
-
-
Choi, B.G.1
Vilahur, G.2
Yadegar, D.3
Viles-Gonzalez, J.F.4
Badimon, J.J.5
-
48
-
-
30144445801
-
Prolonged-release nicotinic acid: A review of its use in the treatment of dyslipidaemia
-
McCormack PL, Keating GM: Prolonged-release nicotinic acid: a review of its use in the treatment of dyslipidaemia. Drugs 2005, 65:2719-2740.
-
(2005)
Drugs
, vol.65
, pp. 2719-2740
-
-
McCormack, P.L.1
Keating, G.M.2
-
49
-
-
0025148561
-
Nicotinic acid as therapy for dyslipidemia in non-insulin-dependent diabetes mellitus
-
Garg A, Grundy SM: Nicotinic acid as therapy for dyslipidemia in non-insulin-dependent diabetes mellitus. JAMA 1990, 264:723-726.
-
(1990)
JAMA
, vol.264
, pp. 723-726
-
-
Garg, A.1
Grundy, S.M.2
-
50
-
-
0033812857
-
Effects of nicotinic acid on insulin sensitivity and blood pressure in healthy subjects
-
Kelly JJ, Lawson JA, Campbell LV, Storlien LH, Jenkins AB, Whitworth JA, O'Sullivan AJ: Effects of nicotinic acid on insulin sensitivity and blood pressure in healthy subjects. J Hum Hypertens 2000, 14:567-572.
-
(2000)
J Hum Hypertens
, vol.14
, pp. 567-572
-
-
Kelly, J.J.1
Lawson, J.A.2
Campbell, L.V.3
Storlien, L.H.4
Jenkins, A.B.5
Whitworth, J.A.6
O'Sullivan, A.J.7
-
51
-
-
0041312408
-
Nicotinic acid-induced insulin resistance is related to increased circulating fatty acids and fat oxidation but not muscle lipid content
-
Poynten AM, Gan SK, Kriketos AD, O'Sullivan A, Kelly JJ, Ellis BA, Chisholm DJ, Campbell LV: Nicotinic acid-induced insulin resistance is related to increased circulating fatty acids and fat oxidation but not muscle lipid content. Metabolism 2003, 52:699-704.
-
(2003)
Metabolism
, vol.52
, pp. 699-704
-
-
Poynten, A.M.1
Gan, S.K.2
Kriketos, A.D.3
O'Sullivan, A.4
Kelly, J.J.5
Ellis, B.A.6
Chisholm, D.J.7
Campbell, L.V.8
-
52
-
-
19344370665
-
Influence of extended-release nicotinic acid on nonesterified fatty acid flux in the metabolic syndrome with atherogenic dyslipidemia
-
Vega GL, Cater NB, Meguro S, Grundy SM: Influence of extended-release nicotinic acid on nonesterified fatty acid flux in the metabolic syndrome with atherogenic dyslipidemia. Am J Cardiol 2005, 95:1309-1313.
-
(2005)
Am J Cardiol
, vol.95
, pp. 1309-1313
-
-
Vega, G.L.1
Cater, N.B.2
Meguro, S.3
Grundy, S.M.4
-
53
-
-
0018776515
-
The effects of cholestyramine on high density lipoprotein metabolism
-
Shepherd J, Packard CJ, Morgan HG, Third JL, Stewart JM, Lawrie TD: The effects of cholestyramine on high density lipoprotein metabolism. Atherosclerosis 1979, 33:433-444.
-
(1979)
Atherosclerosis
, vol.33
, pp. 433-444
-
-
Shepherd, J.1
Packard, C.J.2
Morgan, H.G.3
Third, J.L.4
Stewart, J.M.5
Lawrie, T.D.6
-
54
-
-
0021349709
-
The relationship of reduction in incidence of coronary heart disease to cholesterol lowering
-
The Lipid Research Clinics Coronary Primary Prevention Trial results. II
-
The Lipid Research Clinics Coronary Primary Prevention Trial results. II: The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. JAMA 1984, 251:365-374.
-
(1984)
JAMA
, vol.251
, pp. 365-374
-
-
-
55
-
-
33645098531
-
Clinical utility of bile acid sequestrants in the treatment of dyslipidemia: A scientific review
-
Insull W Jr: Clinical utility of bile acid sequestrants in the treatment of dyslipidemia: a scientific review. South Med J 2006, 99:257-273.
-
(2006)
South Med J
, vol.99
, pp. 257-273
-
-
Insull Jr., W.1
-
57
-
-
0037044454
-
Inhibition of intestinal cholesterol absorption by ezetimibe in humans
-
Sudhop T, Lutjohann D, Kodal A, Igel M, Tribble DL, Shah S, Perevozskaya I, von Bergmann K: Inhibition of intestinal cholesterol absorption by ezetimibe in humans. Circulation 2002, 106:1943-1948.
-
(2002)
Circulation
, vol.106
, pp. 1943-1948
-
-
Sudhop, T.1
Lutjohann, D.2
Kodal, A.3
Igel, M.4
Tribble, D.L.5
Shah, S.6
Perevozskaya, I.7
von Bergmann, K.8
-
58
-
-
0035572836
-
Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice
-
Davis HR Jr, Compton DS, Hoos L, Tetzloff G: Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice. Arterioscler Thromb Vasc Biol 2001, 21:2032-2038.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 2032-2038
-
-
Davis Jr., H.R.1
Compton, D.S.2
Hoos, L.3
Tetzloff, G.4
-
59
-
-
29444432231
-
Increasing high-density lipoprotein cholesterol through cholesteryl Ester transfer protein inhibition: A next step in the fight against cardiovascular disease?
-
Van der Steeg WA, El-Harchaoui K, Kuivenhoven JA, Kastelein JJ: Increasing high-density lipoprotein cholesterol through cholesteryl Ester transfer protein inhibition: a next step in the fight against cardiovascular disease? Curr Drug Targets Cardiovasc Haematol Disord 2005, 5:481-488.
-
(2005)
Curr Drug Targets Cardiovasc Haematol Disord
, vol.5
, pp. 481-488
-
-
Van der Steeg, W.A.1
El-Harchaoui, K.2
Kuivenhoven, J.A.3
Kastelein, J.J.4
-
60
-
-
33746068600
-
Cholesteryl ester transfer protein inhibition, high-density lipoprotein metabolism and heart disease risk reduction
-
Schaefer EJ, Asztalos BF: Cholesteryl ester transfer protein inhibition, high-density lipoprotein metabolism and heart disease risk reduction. Curr Opin Lipidol 2006, 17:394-398.
-
(2006)
Curr Opin Lipidol
, vol.17
, pp. 394-398
-
-
Schaefer, E.J.1
Asztalos, B.F.2
-
61
-
-
1842815777
-
Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol
-
Brousseau ME, Schaefer EJ, Wolfe ML, Bloedon LT, Digenio AG, Clark RW, Mancuso JP, Rader DJ: Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol. N Engl J Med 2004, 350:1505-1515.
-
(2004)
N Engl J Med
, vol.350
, pp. 1505-1515
-
-
Brousseau, M.E.1
Schaefer, E.J.2
Wolfe, M.L.3
Bloedon, L.T.4
Digenio, A.G.5
Clark, R.W.6
Mancuso, J.P.7
Rader, D.J.8
-
62
-
-
0037035459
-
Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II dose-response study
-
de Grooth GJ, Kuivenhoven JA, Stalenhoef AF, de Graaf J, Zwinderman AH, Posma JL, van Tol A, Kastelein JJ: Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study. Circulation 2002, 105:2159-2165.
-
(2002)
Circulation
, vol.105
, pp. 2159-2165
-
-
de Grooth, G.J.1
Kuivenhoven, J.A.2
Stalenhoef, A.F.3
de Graaf, J.4
Zwinderman, A.H.5
Posma, J.L.6
van Tol, A.7
Kastelein, J.J.8
-
63
-
-
4043160640
-
Cardiovascular disease with diabetes or the metabolic syndrome: Should statins or fibrates be first line lipid therapy?
-
Robins SJ: Cardiovascular disease with diabetes or the metabolic syndrome: should statins or fibrates be first line lipid therapy? Curr Opin Lipidol 2003, 14:575-583.
-
(2003)
Curr Opin Lipidol
, vol.14
, pp. 575-583
-
-
Robins, S.J.1
-
64
-
-
4644318535
-
Macrovascular complications of metabolic syndrome: An early intervention is imperative
-
Tenenbaum A, Motro M, Schwammenthal E, Fisman EZ: Macrovascular complications of metabolic syndrome: an early intervention is imperative. Int J Cardiol 2004, 97:167-172.
-
(2004)
Int J Cardiol
, vol.97
, pp. 167-172
-
-
Tenenbaum, A.1
Motro, M.2
Schwammenthal, E.3
Fisman, E.Z.4
-
65
-
-
5144227019
-
The role of fibrates in managing hyperlipidemia: Mechanisms of action and clinical efficacy
-
Fazio S, Linton MF: The role of fibrates in managing hyperlipidemia: mechanisms of action and clinical efficacy. Curr Atheroscler Rep 2004, 6:148-157.
-
(2004)
Curr Atheroscler Rep
, vol.6
, pp. 148-157
-
-
Fazio, S.1
Linton, M.F.2
-
66
-
-
1042302811
-
Role of fibrates in reducing coronary risk: A UK Consensus
-
Role of fibrates in reducing coronary risk: a UK Consensus. Curr Med Res Opin 2004, 20:241-247.
-
(2004)
Curr Med Res Opin
, vol.20
, pp. 241-247
-
-
-
67
-
-
1942440458
-
Bezafibrate and simvastatin: Different beneficial effects for different therapeutic aims
-
Tenenbaum A, Fisman EZ, Motro M: Bezafibrate and simvastatin: different beneficial effects for different therapeutic aims. J Clin Endocrinol Metab 2004, 89:1978.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1978
-
-
Tenenbaum, A.1
Fisman, E.Z.2
Motro, M.3
-
68
-
-
33746038089
-
Fibric acid derivatives in cardiovascular disease prevention: Results from the large clinical trials
-
Robins SJ, Bloomfield HE: Fibric acid derivatives in cardiovascular disease prevention: results from the large clinical trials. Curr Opin Lipidol 2006, 17:431-439.
-
(2006)
Curr Opin Lipidol
, vol.17
, pp. 431-439
-
-
Robins, S.J.1
Bloomfield, H.E.2
-
69
-
-
29444445041
-
Role for fibrate therapy in diabetes: Evidence before FIELD
-
Verges B: Role for fibrate therapy in diabetes: evidence before FIELD. Curr Opin Lipidol 2005, 16:648-651.
-
(2005)
Curr Opin Lipidol
, vol.16
, pp. 648-651
-
-
Verges, B.1
-
70
-
-
0028673603
-
Fluvastatin in combination with other lipid-lowering agents
-
Jokubaitis LA: Fluvastatin in combination with other lipid-lowering agents. Br J Clin Pract 1996:28-32.
-
(1996)
Br J Clin Pract
, pp. 28-32
-
-
Jokubaitis, L.A.1
-
71
-
-
0034127122
-
Bezafibrate and simvastatin combination therapy for diabetic dyslipidaemia: Efficacy and safety
-
Gavish D, Leibovitz E, Shapira I, Rubinstein A: Bezafibrate and simvastatin combination therapy for diabetic dyslipidaemia: efficacy and safety. J Intern Med 2000, 247:563-569.
-
(2000)
J Intern Med
, vol.247
, pp. 563-569
-
-
Gavish, D.1
Leibovitz, E.2
Shapira, I.3
Rubinstein, A.4
-
72
-
-
0035337643
-
Plasma concentrations of active Iovastatin acid are markedly increased by gemfibrozil but not by bezafibrate
-
Kyrklund C, Backman JT, Kivisto KT, Neuvonen M, Laitila J, Neuvonen PJ: Plasma concentrations of active Iovastatin acid are markedly increased by gemfibrozil but not by bezafibrate. Clin Pharmacol Ther 2001, 69:340-345.
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 340-345
-
-
Kyrklund, C.1
Backman, J.T.2
Kivisto, K.T.3
Neuvonen, M.4
Laitila, J.5
Neuvonen, P.J.6
-
73
-
-
0032925188
-
A comparison of the use, effectiveness and safety of bezafibrate, gemfibrozil and simvastatin in normal clinical practice using the New Zealand Intensive Medicines Monitoring Programme (IMMP)
-
Beggs PW, Clark DW, Williams SM, Coulter DM: A comparison of the use, effectiveness and safety of bezafibrate, gemfibrozil and simvastatin in normal clinical practice using the New Zealand Intensive Medicines Monitoring Programme (IMMP). Br J Clin Pharmacol 1999, 47:99-104.
-
(1999)
Br J Clin Pharmacol
, vol.47
, pp. 99-104
-
-
Beggs, P.W.1
Clark, D.W.2
Williams, S.M.3
Coulter, D.M.4
-
74
-
-
0141794167
-
Effects of baseline level of triglycerides on changes in lipid levels from combined fluvastatin + fibrate (bezafibrate, fenofibrate, or gemfibrozil)
-
Farnier M, Salko T, Isaacsohn JL, Troendle AJ, Dejager S, Gonasun L: Effects of baseline level of triglycerides on changes in lipid levels from combined fluvastatin + fibrate (bezafibrate, fenofibrate, or gemfibrozil). Am J Cardiol 2003, 92:794-797.
-
(2003)
Am J Cardiol
, vol.92
, pp. 794-797
-
-
Farnier, M.1
Salko, T.2
Isaacsohn, J.L.3
Troendle, A.J.4
Dejager, S.5
Gonasun, L.6
-
75
-
-
0038236574
-
Combination therapy with an HMG-CoA reductase inhibitor and a fibric acid derivative: A critical review of potential benefits and drawbacks
-
Farnier M: Combination therapy with an HMG-CoA reductase inhibitor and a fibric acid derivative: a critical review of potential benefits and drawbacks. Am J Cardiovasc Drugs 2003, 3:169-178.
-
(2003)
Am J Cardiovasc Drugs
, vol.3
, pp. 169-178
-
-
Farnier, M.1
-
76
-
-
0034924212
-
Statin-fibrate combination therapy
-
Shek A, Ferrill MJ: Statin-fibrate combination therapy. Ann Pharmacother 2001, 35:908-917.
-
(2001)
Ann Pharmacother
, vol.35
, pp. 908-917
-
-
Shek, A.1
Ferrill, M.J.2
-
77
-
-
0023001772
-
Fifteen year mortality in Coronary Drug Project patients: Long-term benefit with niacin
-
Canner PL, Berge KG, Wenger NK, Stamler J, Friedman L, Prineas RJ, Friedewald W: Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin. J Am Coll Cardiol 1986, 8:1245-1255.
-
(1986)
J Am Coll Cardiol
, vol.8
, pp. 1245-1255
-
-
Canner, P.L.1
Berge, K.G.2
Wenger, N.K.3
Stamler, J.4
Friedman, L.5
Prineas, R.J.6
Friedewald, W.7
-
78
-
-
12744255447
-
Simvastatin plus ezetimibe: Combination therapy for the management of dyslipidaemia
-
Toth PP, Davidson MH: Simvastatin plus ezetimibe: combination therapy for the management of dyslipidaemia. Expert Opin Pharmacother 2005, 6:131-139.
-
(2005)
Expert Opin Pharmacother
, vol.6
, pp. 131-139
-
-
Toth, P.P.1
Davidson, M.H.2
|