-
1
-
-
0032557425
-
Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis
-
Atwood C.S., Moir R.D., Huang X., Scarpa R.C., Bacarra N.M., Romano D.M., Hartshorn M.A., Tanzi R.E., and Bush A.I. Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis. J. Biol. Chem. 273 (1998) 12817-12826
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12817-12826
-
-
Atwood, C.S.1
Moir, R.D.2
Huang, X.3
Scarpa, R.C.4
Bacarra, N.M.5
Romano, D.M.6
Hartshorn, M.A.7
Tanzi, R.E.8
Bush, A.I.9
-
3
-
-
0017802689
-
A sedimentation equilibrium method for determining molecular weights of proteins with a tabletop high speed air turbine centrifuge
-
Bothwell M.A., Howlett G.J., and Schachman H.K. A sedimentation equilibrium method for determining molecular weights of proteins with a tabletop high speed air turbine centrifuge. J. Biol. Chem. 253 (1978) 2073-2077
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 2073-2077
-
-
Bothwell, M.A.1
Howlett, G.J.2
Schachman, H.K.3
-
4
-
-
15744402739
-
Metal-catalyzed oxidation of alpha-synuclein: Helping to define the relationship between oligomers, protofibrils, and filaments
-
Cole N.B., Murphy D.D., Lebowitz J., Di Noto L., Levine R.L., and Nussbaum R.L. Metal-catalyzed oxidation of alpha-synuclein: Helping to define the relationship between oligomers, protofibrils, and filaments. J. Biol. Chem. 280 (2005) 9678-9690
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 9678-9690
-
-
Cole, N.B.1
Murphy, D.D.2
Lebowitz, J.3
Di Noto, L.4
Levine, R.L.5
Nussbaum, R.L.6
-
5
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy
-
Conway K.A., Lee S.J., Rochet J.C., Ding T.T., Williamson R.E., and Lansbury Jr. P.T. Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy. Proc. Natl. Acad. Sci. USA 97 (2000) 571-576
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.J.2
Rochet, J.C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury Jr., P.T.6
-
6
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability
-
Dahlgren K.N., Manelli A.M., Stine Jr. W.B., Baker L.K., Krafft G.A., and LaDu M.J. Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability. J. Biol. Chem. 277 (2002) 32046-32053
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine Jr., W.B.3
Baker, L.K.4
Krafft, G.A.5
LaDu, M.J.6
-
7
-
-
0027410312
-
Rapid and accurate microfractionation of the contents of small centrifuge tubes: Application in the measurement of molecular weight of proteins via sedimentation equilibrium
-
Darawshe S., Rivas G., and Minton A.P. Rapid and accurate microfractionation of the contents of small centrifuge tubes: Application in the measurement of molecular weight of proteins via sedimentation equilibrium. Anal. Biochem. 209 (1993) 130-135
-
(1993)
Anal. Biochem.
, vol.209
, pp. 130-135
-
-
Darawshe, S.1
Rivas, G.2
Minton, A.P.3
-
8
-
-
0031982612
-
Determination of molecular parameters by fitting sedimentation data to finite-element solutions of the Lamm equation
-
Demeler B., and Saber H. Determination of molecular parameters by fitting sedimentation data to finite-element solutions of the Lamm equation. Biophys. J. 74 (1998) 444-454
-
(1998)
Biophys. J.
, vol.74
, pp. 444-454
-
-
Demeler, B.1
Saber, H.2
-
9
-
-
0036882160
-
Acid denaturation of alpha1-antitrypsin: Characterization of a novel mechanism of serpin polymerization
-
Devlin G.L., Chow M.K., Howlett G.J., and Bottomley S.P. Acid denaturation of alpha1-antitrypsin: Characterization of a novel mechanism of serpin polymerization. J. Mol. Biol. 324 (2002) 859-870
-
(2002)
J. Mol. Biol.
, vol.324
, pp. 859-870
-
-
Devlin, G.L.1
Chow, M.K.2
Howlett, G.J.3
Bottomley, S.P.4
-
12
-
-
0035949632
-
Anion shielding of electrostatic repulsions in transthyretin modulates stability and amyloidosis: Insight into the chaotrope unfolding dichotomy
-
Hammarstrom P., Jiang X., Deechongkit S., and Kelly J.W. Anion shielding of electrostatic repulsions in transthyretin modulates stability and amyloidosis: Insight into the chaotrope unfolding dichotomy. Biochemistry 40 (2001) 11453-11459
-
(2001)
Biochemistry
, vol.40
, pp. 11453-11459
-
-
Hammarstrom, P.1
Jiang, X.2
Deechongkit, S.3
Kelly, J.W.4
-
13
-
-
0034682559
-
Human apolipoprotein C II forms twisted amyloid ribbons and closed loops
-
Hatters D.M., MacPhee C.E., Sawyer W.H., and Howlett G.J. Human apolipoprotein C II forms twisted amyloid ribbons and closed loops. Biochemistry 39 (2000) 8276-8283
-
(2000)
Biochemistry
, vol.39
, pp. 8276-8283
-
-
Hatters, D.M.1
MacPhee, C.E.2
Sawyer, W.H.3
Howlett, G.J.4
-
14
-
-
0037040878
-
Macromolecular crowding accelerates amyloid formation by human apolipoprotein C-II
-
Hatters D.M., Minton A.P., and Howlett G.J. Macromolecular crowding accelerates amyloid formation by human apolipoprotein C-II. J. Biol. Chem. 277 (2002) 7824-7830
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7824-7830
-
-
Hatters, D.M.1
Minton, A.P.2
Howlett, G.J.3
-
15
-
-
0029031935
-
Imaging amyloidosis with radiolabelled SAP
-
Hawkins P.N., and Pepys M.B. Imaging amyloidosis with radiolabelled SAP. Eur. J. Nucl. Med. 22 (1995) 595-599
-
(1995)
Eur. J. Nucl. Med.
, vol.22
, pp. 595-599
-
-
Hawkins, P.N.1
Pepys, M.B.2
-
16
-
-
36849124197
-
Sedimentation constants of broken and wormlike coils
-
Hearst J.E., and Stockmayer W.H. Sedimentation constants of broken and wormlike coils. J. Chem. Phys. (1962) 1425-1433
-
(1962)
J. Chem. Phys.
, pp. 1425-1433
-
-
Hearst, J.E.1
Stockmayer, W.H.2
-
17
-
-
0000198303
-
An approximate solution of the Lamm equation
-
Holloday L. An approximate solution of the Lamm equation. Biophys. Chem. 10 (1979) 187-190
-
(1979)
Biophys. Chem.
, vol.10
, pp. 187-190
-
-
Holloday, L.1
-
18
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R., Head E., Thompson J.L., McIntire T.M., Milton S.C., Cotman C.W., and Glabe C.G. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300 (2003) 486-489
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
19
-
-
0035812658
-
Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis
-
Kirkitadze M.D., Condron M.M., and Teplow D.B. Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis. J. Mol. Biol. 312 (2001) 1103-1119
-
(2001)
J. Mol. Biol.
, vol.312
, pp. 1103-1119
-
-
Kirkitadze, M.D.1
Condron, M.M.2
Teplow, D.B.3
-
20
-
-
0032558978
-
Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: Implications for wild-type, V30M, and L55P amyloid fibril formation
-
Lashuel H.A., Lai Z., and Kelly J.W. Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: Implications for wild-type, V30M, and L55P amyloid fibril formation. Biochemistry 37 (1998) 17851-17864
-
(1998)
Biochemistry
, vol.37
, pp. 17851-17864
-
-
Lashuel, H.A.1
Lai, Z.2
Kelly, J.W.3
-
21
-
-
0037044835
-
New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease
-
Lashuel H.A., Hartley D.M., Balakhaneh D., Aggarwal A., Teichberg S., and Callaway D.J. New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease. J. Biol. Chem. 277 (2002) 42881-42890
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42881-42890
-
-
Lashuel, H.A.1
Hartley, D.M.2
Balakhaneh, D.3
Aggarwal, A.4
Teichberg, S.5
Callaway, D.J.6
-
22
-
-
0036415838
-
Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils
-
Lashuel H.A., Petre B.M., Wall J., Simon M., Nowak R.J., Walz T., and Lansbury Jr. P.T. Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils. J. Mol. Biol. 322 (2002) 1089-1102
-
(2002)
J. Mol. Biol.
, vol.322
, pp. 1089-1102
-
-
Lashuel, H.A.1
Petre, B.M.2
Wall, J.3
Simon, M.4
Nowak, R.J.5
Walz, T.6
Lansbury Jr., P.T.7
-
23
-
-
0037380769
-
Sedimentation velocity analysis of flexible macromolecules: Self-association and tangling of amyloid fibrils
-
MacRaild C.A., Hatters D.M., Lawrence L.J., and Howlett G.J. Sedimentation velocity analysis of flexible macromolecules: Self-association and tangling of amyloid fibrils. Biophys. J. 84 (2003) 2562-2569
-
(2003)
Biophys. J.
, vol.84
, pp. 2562-2569
-
-
MacRaild, C.A.1
Hatters, D.M.2
Lawrence, L.J.3
Howlett, G.J.4
-
24
-
-
2442642590
-
Non-fibrillar components of amyloid deposits mediate the self-association and tangling of amyloid fibrils
-
MacRaild C.A., Stewart C.R., Mok Y.F., Gunzburg M.J., Perugini M.A., Lawrence L.J., Tirtaatmadja V., Cooper-White J.J., and Howlett G.J. Non-fibrillar components of amyloid deposits mediate the self-association and tangling of amyloid fibrils. J. Biol. Chem. 279 (2004) 21038-21045
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21038-21045
-
-
MacRaild, C.A.1
Stewart, C.R.2
Mok, Y.F.3
Gunzburg, M.J.4
Perugini, M.A.5
Lawrence, L.J.6
Tirtaatmadja, V.7
Cooper-White, J.J.8
Howlett, G.J.9
-
25
-
-
0031036440
-
An improved function for fitting sedimentation velocity data for low-molecular-weight solutes
-
Philo J.S. An improved function for fitting sedimentation velocity data for low-molecular-weight solutes. Biophys. J. 72 (1997) 435-444
-
(1997)
Biophys. J.
, vol.72
, pp. 435-444
-
-
Philo, J.S.1
-
26
-
-
0034654352
-
A method for directly fitting the time derivative of sedimentation velocity data and an alternative algorithm for calculating sedimentation coefficient distribution functions
-
Philo J.S. A method for directly fitting the time derivative of sedimentation velocity data and an alternative algorithm for calculating sedimentation coefficient distribution functions. Anal. Biochem. 279 (2000) 151-163
-
(2000)
Anal. Biochem.
, vol.279
, pp. 151-163
-
-
Philo, J.S.1
-
27
-
-
1542357685
-
Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture
-
Reixach N., Deechongkit S., Jiang X., Kelly J.W., and Buxbaum J.N. Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture. Proc. Natl. Acad. Sci. USA 101 (2004) 2817-2822
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2817-2822
-
-
Reixach, N.1
Deechongkit, S.2
Jiang, X.3
Kelly, J.W.4
Buxbaum, J.N.5
-
28
-
-
9444245809
-
Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease
-
Roher A.E., Chaney M.O., Kuo Y.M., Webster S.D., Stine W.B., Haverkamp L.J., Woods A.S., Cotter R.J., Tuohy J.M., Krafft G.A., Bonnell B.S., and Emmerling M.R. Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease. J. Biol. Chem. 271 (1996) 20631-20635
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20631-20635
-
-
Roher, A.E.1
Chaney, M.O.2
Kuo, Y.M.3
Webster, S.D.4
Stine, W.B.5
Haverkamp, L.J.6
Woods, A.S.7
Cotter, R.J.8
Tuohy, J.M.9
Krafft, G.A.10
Bonnell, B.S.11
Emmerling, M.R.12
-
30
-
-
0031688168
-
Sedimentation analysis of noninteracting and self-associating solutes using numerical solutions to the Lamm equation
-
Schuck P. Sedimentation analysis of noninteracting and self-associating solutes using numerical solutions to the Lamm equation. Biophys. J. 75 (1998) 1503-1512
-
(1998)
Biophys. J.
, vol.75
, pp. 1503-1512
-
-
Schuck, P.1
-
31
-
-
0034009520
-
Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and Lamm equation modeling
-
Schuck P. Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and Lamm equation modeling. Biophys. J. 78 (2000) 1606-1619
-
(2000)
Biophys. J.
, vol.78
, pp. 1606-1619
-
-
Schuck, P.1
-
32
-
-
0033058274
-
Direct sedimentation analysis of interference optical data in analytical ultracentrifugation
-
Schuck P., and Demeler B. Direct sedimentation analysis of interference optical data in analytical ultracentrifugation. Biophys. J. 76 (1999) 2288-2296
-
(1999)
Biophys. J.
, vol.76
, pp. 2288-2296
-
-
Schuck, P.1
Demeler, B.2
-
33
-
-
0034668130
-
Determination of the sedimentation coefficient distribution by least-squares boundary modeling
-
Schuck P., and Rossmanith P. Determination of the sedimentation coefficient distribution by least-squares boundary modeling. Biopolymers 54 (2000) 328-341
-
(2000)
Biopolymers
, vol.54
, pp. 328-341
-
-
Schuck, P.1
Rossmanith, P.2
-
34
-
-
0036154258
-
Size-distribution analysis of proteins by analytical ultracentrifugation: Strategies and application to model systems
-
Schuck P., Perugini M.A., Gonzales N.R., Howlett G.J., and Schubert D. Size-distribution analysis of proteins by analytical ultracentrifugation: Strategies and application to model systems. Biophys. J. 82 (2002) 1096-1111
-
(2002)
Biophys. J.
, vol.82
, pp. 1096-1111
-
-
Schuck, P.1
Perugini, M.A.2
Gonzales, N.R.3
Howlett, G.J.4
Schubert, D.5
-
35
-
-
0033849738
-
Review: History of the amyloid fibril
-
Sipe J.D., and Cohen A.S. Review: History of the amyloid fibril. J. Struct. Biol. 130 (2000) 88-98
-
(2000)
J. Struct. Biol.
, vol.130
, pp. 88-98
-
-
Sipe, J.D.1
Cohen, A.S.2
-
36
-
-
0026747656
-
Boundary analysis in sedimentation transport experiments: A procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile
-
Stafford III W.F. Boundary analysis in sedimentation transport experiments: A procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile. Anal. Biochem. 203 (1992) 295-301
-
(1992)
Anal. Biochem.
, vol.203
, pp. 295-301
-
-
Stafford III, W.F.1
-
37
-
-
0038176528
-
In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis
-
Stine Jr. W.B., Dahlgren K.N., Krafft G.A., and LaDu M.J. In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis. J. Biol. Chem. 278 (2003) 11612-11622
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11612-11622
-
-
Stine Jr., W.B.1
Dahlgren, K.N.2
Krafft, G.A.3
LaDu, M.J.4
-
39
-
-
0029010736
-
Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis
-
Tennent G.A., Lovat L.B., and Pepys M.B. Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis. Proc. Natl. Acad. Sci. USA 92 (1995) 4299-4303
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4299-4303
-
-
Tennent, G.A.1
Lovat, L.B.2
Pepys, M.B.3
-
40
-
-
0017806223
-
Boundary analysis of sedimentation velocity experiments with monodisperse and paucidisperse solutes
-
VanHolde K., and Weischet W. Boundary analysis of sedimentation velocity experiments with monodisperse and paucidisperse solutes. Biopolymers 17 (1978) 1387-1403
-
(1978)
Biopolymers
, vol.17
, pp. 1387-1403
-
-
VanHolde, K.1
Weischet, W.2
-
41
-
-
0013575443
-
Sedimentation
-
VanHolde K. (Ed), Prentice Hall, Englewood Cliffs, NJ
-
VanHolde K. Sedimentation. In: VanHolde K. (Ed). "Physical Biochemistry" (1985), Prentice Hall, Englewood Cliffs, NJ 110-136
-
(1985)
"Physical Biochemistry"
, pp. 110-136
-
-
VanHolde, K.1
-
42
-
-
0037059598
-
Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus
-
Wang H.W., Pasternak J.F., Kuo H., Ristic H., Lambert M.P., Chromy B., Viola K.L., Klein W.L., Stine W.B., Krafft G.A., and Trommer B.L. Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus. Brain Res. 924 (2002) 133-140
-
(2002)
Brain Res.
, vol.924
, pp. 133-140
-
-
Wang, H.W.1
Pasternak, J.F.2
Kuo, H.3
Ristic, H.4
Lambert, M.P.5
Chromy, B.6
Viola, K.L.7
Klein, W.L.8
Stine, W.B.9
Krafft, G.A.10
Trommer, B.L.11
-
43
-
-
18844427273
-
Structural properties of Abeta protofibrils stabilized by a small molecule
-
Williams A.D., Sega M., Chen M., Kheterpal I., Geva M., Berthelier V., Kaleta D.T., Cook K.D., and Wetzel R. Structural properties of Abeta protofibrils stabilized by a small molecule. Proc. Natl. Acad. Sci. USA 102 (2005) 7115-7120
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 7115-7120
-
-
Williams, A.D.1
Sega, M.2
Chen, M.3
Kheterpal, I.4
Geva, M.5
Berthelier, V.6
Kaleta, D.T.7
Cook, K.D.8
Wetzel, R.9
|