Hepatocyte transplantation: Potential of hepatocyte progenitor cells and bone marrow derived stem cells

Swiss Medical Weekly

Volumn 136, Issue 35-36, 2006, Pages 552-556

  Stieger, Bruno ^a   Peters, Rowayda ^a   Sidler, Marguerite Anne ^a   Meier, Peter J ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Differentiation; Failure; Liver; Regeneration; Stem cell; Transplantation

Indexed keywords

CARBON TETRACHLORIDE; N (2 FLUORENYL)ACETAMIDE;

CELL DIFFERENTIATION; CELL DIVISION; HEMATOPOIETIC STEM CELL; HEPATOCYTE TRANSPLANTATION; LIVER CARCINOGENESIS; LIVER CELL; LIVER INJURY; LIVER REGENERATION; LIVER RESECTION; NONHUMAN; SHORT SURVEY; STEM CELL;

EID: 33749496430     PISSN: 14247860     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (45)

1. Arias IM, Boyer JL, Fausto N, Chisari FV, Schachter D, Shafritz DA. The Liver: Biology and Pathobiology. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2001; 1088.
2. Overturf K, al Dhalimy M, Ou CN, Finegold M, Grompe M. Serial transplantation reveals the stem-cell-like regenerative potential of adult mouse hepatocytes. Am J Pathol 1997;151:1273-80.
3. Grompe M. Principles of therapeutic liver repopulation. J Inherit Metab Dis 2006;29:421-5.
4. Fox IJ, Chowdhury JR. Hepatocyte transplantation. Am J Transplant 2004;4(Suppl 6):7-13.
5. Fox IJ, Chowdhury JR, Kaufman SS, Goertzen TC, Chowdhury NR, Warkentin PI, et al. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation. N Engl J Med 1998;338:1422-6.
6. Farber E. Similarities in the sequence of early histological changes induced in the liver of the rat by ethionine, 2-acetylamino-fluorene, and 3′-methyl-4-dimethylaminoazobenzene. Cancer Res 1956;16:142-8.
7. Sell S. Heterogeneity and plasticity of hepatocyte lineage cells. Hepatology 2001;33:738-50.
8. Fausto N, Campbell JS. The role of hepatocytes and oval cells in liver regeneration and repopulation. Mech Dev 2003;120:117-30.
9. Wang X, Foster M, Al-Dhalimy M, Lagasse E, Finegold M, Grompe M. The origin and liver repopulating capacity of murine oval cells. Proc Natl Acad Sci U S A 2003;100(Suppl 1):11881-8.
10. Evarts RP, Nagy P, Nakatsukasa H, Marsden E, Thorgeirsson SS. In vivo differentiation of rat liver oval cells into hepatocytes. Cancer Res 1989;49:1541-7.
11. Tsao MS, Smith JD, Nelson KG, Grisham JW. A diploid epithelial cell line from normal adult rat liver with phenotypic properties of "oval" cells. Exp Cell Res 1984;154:38-52.
12. Lazaro CA, Rhim JA, Yamada Y, Fausto N. Generation of hepatocytes from oval cell precursors in culture. Cancer Res 1998;58:5514-22.
13. Petersen BE, Bowen WC, Patrene KD, Mars WM, Sullivan AK, Murase N, et al. Bone marrow as a potential source of hepatic oval cells. Science 1999;284:1168-70.
14. Menthena A, Deb N, Oertel M, Grozdanov PN, Sandhu J, Shah S, et al. Bone marrow progenitors are not the source of expanding oval cells in injured liver. Stem Cells 2004;22:1049-61.
15. Alison M. Liver stem cells: a two compartment system. Curr Opin Cell Biol 1998;10:710-5.
16. Shafritz DA, Dabeva MD. Liver stem cells and model systems for liver repopulation. J Hepatol 2002;36:552-64.
17. Sell S. The hepatocyte: heterogeneity and plasticity of liver cells. Int J Biochem Cell Biol 2003;35:267-71.
18. Fausto N. Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells. Hepatology 2004;39:1477-87.
19. Laurson J, Selden C, Hodgson HJ. Hepatocyte progenitors in man and in rodents - multiple pathways, multiple candidates. Int J Exp Pathol 2005;86:1-18.
20. Tosh D, Strain A. Liver stem cells - prospects for clinical use. J Hepatol 2005;42(Suppl):S75-84.
21. Mitaka T. The current status of primary hepatocyte culture. Int J Exp Pathol 1998;79:393-409.
22. Mitaka T, Mizuguchi T, Sato F, Mochizuki C, Mochizuki Y. Growth and maturation of small hepatocytes. J Gastroenterol Hepatol 1998;13(Suppl):S70-7.
23. Mitaka T, Sato F, Mizuguchi T, Yokono T, Mochizuki Y. Reconstruction of hepatic organoid by rat small hepatocytes and hepatic nonparenchymal cells. Hepatology 1999;29:111-25.
24. Sidler Pfandler MA, Hochli M, Inderbitzin D, Meier PJ, Stieger B. Small hepatocytes in culture develop polarized transporter expression and differentiation. J Cell Sci 2004;117:4077-87.
25. Meier PJ, Stieger B. Bile salt transporters. Annu Rev Physiol 2002;64:635-61.
26. Gao B, St Pierre MV, Stieger B, Meier PJ. Differential expression of bile salt and organic anion transporters in developing rat liver. J Hepatol 2004;41:201-8.
27. Shiojiri N, Lemire JM, Fausto N. Cell lineages and oval cell progenitors in rat liver development. Cancer Res 1991;51:2611-20.
28. Theise ND, Badve S, Saxena R, Henegariu O, Sell S, Crawford JM, et al. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 2000;31:235-40.
29. Theise ND, Nimmakayalu M, Gardner R, Illei PB, Morgan G, Teperman L, et al. Liver from bone marrow in humans. Hepatology 2000;32:11-6.
30. Alison MR, Poulsom R, Jeffery R, Dhillon AP, Quaglia A, Jacob J, et al. Hepatocytes from non-hepatic adult stem cells. Nature 2000;406:257.
31. Vassilopoulos G, Wang PR, Russell DW. Transplanted bone marrow regenerates liver by cell fusion. Nature 2003;422:901-4.
32. Wang X, Willenbring H, Akkari Y, Torimaru Y, Foster M, Al-Dhalimy M, et al. Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature 2003;422:897-901.
33. Newsome PN, Johannessen I, Boyle S, Dalakas E, McAulay KA, Samuel K, et al. Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion. Gastroenterology 2003;124:1891-900.
34. Oh SH, Miyazaki M, Kouchi H, Inoue Y, Sakaguchi M, Tsuji T, et al. Hepatocyte growth factor induces differentiation of adult rat bone marrow cells into a hepatocyte lineage in vitro. Biochem Biophys Res Commun 2000;279:500-4.
35. Avital I, Inderbitzin D, Aoki T, Tyan DB, Cohen AH, Ferraresso C, et al. Isolation, characterization, and transplantation of bone marrow-derived hepatocyte stem cells. Biochem Biophys Res Commun 2001;288:156-64.
36. Schwartz RE, Reyes M, Koodie L, Jiang Y, Blackstad M, Lund T, et al. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J Clin Invest 2002;109:1291-302.
37. Hong SH, Gang EJ, Jeong JA, Ahn C, Hwang SH, Yang IH, et al. In vitro differentiation of human umbilical cord blood-derived mesenchymal stem cells into hepatocyte-like cells. Biochem Biophys Res Commun 2005;330:1153-61.
38. Wang Y, Nan X, Li Y, Zhang R, Yue W, Yan F, et al. Induction of umbilical cord blood-derived beta2m-c-Met+ cells into hepatocyte-like cells by coculture with CFSC/HGF cells. Liver Transpl 2005;11:635-43.
39. Ruhnke M, Nussler AK, Ungefroren H, Hengstler JG, Kremer B, Hoeckh W, et al. Human monocyte-derived neohepatocytes: a promising alternative to primary human hepatocytes for autologous cell therapy. Transplantation 2005;79:1097-103.
40. Ruhnke M, Ungefroren H, Nussler A, Martin F, Brulport M, Schormann W, et al. Differentiation of in vitro-modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cells. Gastroenterology 2005;128:1774-86.
41. Theise ND. Restoring balance to liver stem cell research. J Hepatol 2004;41:673-6.
42. Grompe M. The origin of hepatocytes. Gastroenterology 2005;128:2158-60.
43. Kleeberger W, Rothamel T, Glockner S, Flemming P, Lehmann U, Kreipe H. High frequency of epithelial chimerism in liver transplants demonstrated by microdissection and STR-analysis. Hepatology 2002;35:110-6.
44. Ng IO, Chan KL, Shek WH, Lee JM, Fong DY, Lo CM, et al. High frequency of chimerism in transplanted livers. Hepatology 2003;38:989-98.
45. Kanazawa Y, Verma IM. Little evidence of bone marrow-derived hepatocytes in the replacement of injured liver. Proc Natl Acad Sci U S A 2003;100(Suppl 1):11850-3.