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Volumn 19, Issue 4, 2006, Pages 285-291

Induction of apoptosis by L-NMMA, via FKHRL1/ROCK pathway in human gastric cancer cells

Author keywords

Apoptosis; FKHRL1; Gastric carcinoma; Nitric oxide; Signaling

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; ENZYME INHIBITOR; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, HUMAN; FOXO3A PROTEIN, HUMAN; N(G) METHYLARGININE; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; RHO KINASE; RHO-ASSOCIATED KINASE; SIGNAL PEPTIDE;

EID: 33749377182     PISSN: 08953988     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (6)

References (22)
  • 1
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner M O (2000). The biochemistry of apoptosis. Nature 407, 770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 2
    • 0033280669 scopus 로고    scopus 로고
    • Biochemical pathways of caspase activation during apoptosis
    • Budihardjo I, Oliver H, Lutter M, et al. (1999). Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 15, 269-290.
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 269-290
    • Budihardjo, I.1    Oliver, H.2    Lutter, M.3
  • 3
    • 0032575750 scopus 로고    scopus 로고
    • Caspasess: Enemies within
    • Thornbeny N A, Lazebnik Y A (1998). Caspasess: enemies within. Science 281, 1312-1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornbeny, N.A.1    Lazebnik, Y.A.2
  • 4
    • 0028102478 scopus 로고
    • Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE
    • Lazebnik Y A, Kaufmann S H, Desnoyers S, et al. (1994). Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371, 346-347.
    • (1994) Nature , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desnoyers, S.3
  • 5
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green D R, Reed J C (1998). Mitochondria and apoptosis. Science 281, 1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 6
    • 12944270500 scopus 로고    scopus 로고
    • BAR: An apoptosis regulator at the intersection of caspasess and Bcl-2 family proteins
    • Zhang H, Xu Q, Krajewski S, et al. (2000). BAR: an apoptosis regulator at the intersection of caspasess and Bcl-2 family proteins. Proc Natl Acad Sci USA 97, 2597-2602.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2597-2602
    • Zhang, H.1    Xu, Q.2    Krajewski, S.3
  • 7
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcriptional factor
    • Brunet A, Bonni A, Zigmond M J (1999). Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcriptional factor. Cell 96, 857-868.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3
  • 8
    • 0035135841 scopus 로고    scopus 로고
    • Protein kinase SGK mediates survival signals by phosphorylating the Forkhead transcriptional factor FKHRL1 (FOXO3a)
    • Brunet A, Park J, Tran H, et al. (2001). Protein kinase SGK mediates survival signals by phosphorylating the Forkhead transcriptional factor FKHRL1 (FOXO3a). Mol Cell Biol 21, 952-965.
    • (2001) Mol Cell Biol , vol.21 , pp. 952-965
    • Brunet, A.1    Park, J.2    Tran, H.3
  • 9
    • 0035072953 scopus 로고    scopus 로고
    • Membrane Webbing during apoptosis from caspase-mediated activation of ROCK I
    • Coleman M L, Sahai E A, Yeo M, et al. (2001). Membrane Webbing during apoptosis from caspase-mediated activation of ROCK I. Nat Cell Biol 3, 339-345.
    • (2001) Nat Cell Biol , vol.3 , pp. 339-345
    • Coleman, M.L.1    Sahai, E.A.2    Yeo, M.3
  • 10
    • 0035075597 scopus 로고    scopus 로고
    • Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing
    • Sebbagh M, Renvoize C, Hamelin J, et al. (2001). Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing. Nat Cell Biol 3, 346-352.
    • (2001) Nat Cell Biol , vol.3 , pp. 346-352
    • Sebbagh, M.1    Renvoize, C.2    Hamelin, J.3
  • 11
    • 0032546795 scopus 로고    scopus 로고
    • Caspase-3 is required for alpha-fodrin cleavage, but dispensable for cleavage of other death substrates in apoptosis
    • Janicke R U, Sprengart M L, Porter A G (1998). Caspase-3 is required for alpha-fodrin cleavage, but dispensable for cleavage of other death substrates in apoptosis. J Biol Chem 273, 15540-15545.
    • (1998) J Biol Chem , vol.273 , pp. 15540-15545
    • Janicke, R.U.1    Sprengart, M.L.2    Porter, A.G.3
  • 12
    • 11844301247 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase in human gastric carcinoma and its relation to p53, PCNA
    • Wang Y Z, Cao Y Q, Wu J N, et al. (2005). Expression of nitric oxide synthase in human gastric carcinoma and its relation to p53, PCNA. World J Gastroenterol 11, 46-50.
    • (2005) World J Gastroenterol , vol.11 , pp. 46-50
    • Wang, Y.Z.1    Cao, Y.Q.2    Wu, J.N.3
  • 13
    • 0035976043 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase, cyclooxygenase, and p53 in different stages of human gastric cancer
    • Rajnakova A, Moochhala S, Goh P M, et al. (2001). Expression of nitric oxide synthase, cyclooxygenase, and p53 in different stages of human gastric cancer. Cancer Lett 172, 177-185.
    • (2001) Cancer Lett , vol.172 , pp. 177-185
    • Rajnakova, A.1    Moochhala, S.2    Goh, P.M.3
  • 14
    • 0042737444 scopus 로고    scopus 로고
    • The role of nitric oxide in cancer
    • Xu W, Liu L Z, Loizidou M, et al. (2002). The role of nitric oxide in cancer. Cell Res 12, 311-320.
    • (2002) Cell Res , vol.12 , pp. 311-320
    • Xu, W.1    Liu, L.Z.2    Loizidou, M.3
  • 16
    • 0028862782 scopus 로고
    • Bum induced nitric oxide release in humans
    • Gamelli R L, George M, Sharp-Pucci M, et al. (1995). Bum induced nitric oxide release in humans. J Trauma 39, 869-878.
    • (1995) J Trauma , vol.39 , pp. 869-878
    • Gamelli, R.L.1    George, M.2    Sharp-Pucci, M.3
  • 17
    • 0030864875 scopus 로고    scopus 로고
    • Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with down-regulation of Bcl-2
    • Xie K, Wang Y, Huang S, et al. (1997). Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with down-regulation of Bcl-2. Oncogene 15, 771-779.
    • (1997) Oncogene , vol.15 , pp. 771-779
    • Xie, K.1    Wang, Y.2    Huang, S.3
  • 18
    • 0028929559 scopus 로고
    • Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells
    • Xie K, Huang S, Dong Z, et al. (1995). Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. J Exp Med 181, 1333-1343.
    • (1995) J Exp Med , vol.181 , pp. 1333-1343
    • Xie, K.1    Huang, S.2    Dong, Z.3
  • 19
    • 0034643331 scopus 로고    scopus 로고
    • AFX-like forkhead transcriptional factors mediate cell-cycle regulation by ras and PKB through p27kip1
    • Medema R H, Kops G J P L, Bos J L, et al. (2000). AFX-like forkhead transcriptional factors mediate cell-cycle regulation by ras and PKB through p27kip1. Nature 404, 782-787.
    • (2000) Nature , vol.404 , pp. 782-787
    • Medema, R.H.1    Kops, G.J.P.L.2    Bos, J.L.3
  • 20
    • 0033595011 scopus 로고    scopus 로고
    • Protein kinase B/Akt mediated phosphorylation promotes nuclear exclusion of the winged helix transcriptional factor FKHR1
    • Biggs W H, Meisenhelger J, Hunter T, et al. (1999). Protein kinase B/Akt mediated phosphorylation promotes nuclear exclusion of the winged helix transcriptional factor FKHR1. Proc Natl Acad Sci USA 96, 7421-7426.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7421-7426
    • Biggs, W.H.1    Meisenhelger, J.2    Hunter, T.3
  • 21
    • 0037372136 scopus 로고    scopus 로고
    • Nitric oxide suppression triggers apoptosis through the FKHRL1 (FOXO3a)/ROCK kinase pathway in human breast carcinoma cells
    • Zivotije Radisavljevic (2003). Nitric oxide suppression triggers apoptosis through the FKHRL1 (FOXO3a)/ROCK kinase pathway in human breast carcinoma cells. Am Cancer Soc 97, 1358-1363.
    • (2003) Am Cancer Soc , vol.97 , pp. 1358-1363
    • Radisavljevic, Z.1
  • 22
    • 0035074269 scopus 로고    scopus 로고
    • Apoptosis: Caspases orchestrate the ROCK bleb
    • Leverrier Y, Ridley A J (2001). Apoptosis: caspases orchestrate the ROCK bleb. Nat Cell Biol 3, E91-E93.
    • (2001) Nat Cell Biol , vol.3
    • Leverrier, Y.1    Ridley, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.