Molecular aspects of ultraviolet radiation-induced apoptosis in the skin

Journal of Cutaneous Medicine and Surgery

Volumn 9, Issue 6, 2005, Pages 289-295

  Chow, Jeffrey ^a   Tron, Victor A ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 10; CASPASE 8; CYTOKINE; DEATH RECEPTOR 4; FAS ASSOCIATED DEATH DOMAIN PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OXYGEN; OZONE; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RECEPTOR 1;

APOPTOSIS; CELL DEATH; CELL TYPE; DNA DAMAGE; DNA REPAIR; DNA SYNTHESIS; EXCISION REPAIR; GENE MUTATION; GENOTOXICITY; HUMAN; LITERATURE; MOUSE STRAIN; NONHUMAN; PEROXIDATION; PRIORITY JOURNAL; REVIEW; SKIN; SKIN CANCER; TRANSCRIPTION REGULATION; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET C RADIATION; ULTRAVIOLET RADIATION; XERODERMA PIGMENTOSUM;

ANIMALS; APOPTOSIS; CELLS, CULTURED; DNA DAMAGE; DNA REPAIR; HUMANS; INCIDENCE; KERATINOCYTES; MICE; MUTATION; NEOPLASMS, RADIATION-INDUCED; PHOTOCHEMISTRY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SKIN; SKIN NEOPLASMS; TUMOR NECROSIS FACTORS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 33749342156     PISSN: 12034754     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10227-005-0109-0     Document Type: Review

References (73)

1. Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26:239-257.
2. Savill J, Gregory C, Haslett C. Cell biology. Eat me or die. Science 2003; 302:1516-1517.
3. Ziegler U, Groscurth P. Morphological features of cell death. News Physiol Sci 2004; 19:124-128.
4. Zuzarte-Luis V, Hurle JM. Programmed cell death in the developing limb. Int J Dev Biol 2002; 46:871-876.
5. Vaux DL, Korsmeyer SJ. Cell death in development. Cell 1999; 96:245-254.
6. Rathmell JC, Thompson CB. Pathways of apoptosis in lymphocyte development, homeostasis, and disease. Cell 2002; 109(Suppl):S97-107.
7. Fadeel B, Orrenius S, Zhivotovsky B. Apoptosis in human disease: a new skin for the old ceremony?. Biochem Biophys Res Commun 1999; 266:699-717.
8. Laat Ade, Leun JCvan der, Gruijl FR. Carcinogenesis induced by UVA (365-nm) radiation: the dose-time dependence of tumor formation in hairless mice. Carcinogenesis 1997; 18:1013-1020.
9. Slee EA, Keogh SA, Martin SJ. Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release. Cell Death Differ 2000; 7:556-565.
10. Ziegler A, Jonason AS, Leffell DJ, et al. Sunburn and p53 in the onset of skin cancer. Nature 1994; 372:773-776.
11. Cleaver JE, Bootsma D. Xeroderma pigmentosum: biochemical and genetic characteristics. Annu Rev Genet 1975; 9:19-38.
12. Kraemer KH, Lee MM, Scotto J. Xeroderma pigmentosum. Cutaneous, ocular, and neurologic abnormalities in 830 published cases. Arch Dermatol 1987; 123:241-250.
13. Kahn HS, Tatham LM, Patel AV, et al. Increased cancer mortality following a history of nonmelanoma skin cancer. Jama 1998; 280:910-912.
14. Ichihashi M, Ueda M, Budiyanto A, et al. UV-induced skin damage. Toxicology 2003; 189:21-39.
15. Kulms D, Schwarz T. Independent contribution of three different pathways to ultraviolet-B-induced apoptosis. Biochem Pharmacol 2002; 64:837-841.
16. Guzman E, Langowski JL, Owen-Schaub L. Mad dogs, Englishmen and apoptosis: the role of cell death in UV-induced skin cancer. Apoptosis 2003; 8:315-325.
17. Campbell C, Quinn AG, Ro YS, et al. p53 mutations are common and early events that precede tumor invasion in squamous cell neoplasia of the skin. J Invest Dermatol 1993; 100:746-748.
18. Deng C, Zhang P, Harper JW, et al. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 1995; 82:675-684.
19. Tron VA, Trotter MJ, Tang L, et al. p53-regulated apoptosis is differentiation dependent in ultraviolet B-irradiated mouse keratinocytes. Am J Pathol 1998; 153:579-585.
20. Chaturvedi V, Sitailo LA, Qin JZ, et al. Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis. Oncogene 2005 Jun 6; [Epub ahead of print]..
21. Li G, Mitchell DL, Ho VC, et al. Decreased DNA repair but normal apoptosis in ultraviolet-irradiated skin of p53-transgenic mice. Am J Pathol 1996; 148:1113-1123.
22. Chresta CM, Hickman JA. Oddball p53 in testicular tumors. Nat Med 1996; 2:745-746.
23. Ford JM, Hanawalt PC. Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts. J Biol Chem 1997; 272:28073-28080.
24. Smith ML, Fornace AJ Jr. p53-mediated protective responses to UV irradiation. Proc Natl Acad Sci USA 1997; 94:12255-12257.
25. Young LC, Peters AC, Maeda T, et al. DNA mismatch repair protein Msh6 is required for optimal levels of ultraviolet-B-induced apoptosis in primary mouse fibroblasts. J Invest Dermatol 2003; 121:876-880.
26. Peters AC, Young LC, Maeda T, et al. Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation. DNA Repair (Amst) 2003; 2:427-435.
27. Young LC, Hays JB, Tron VA, et al. DNA mismatch repair proteins: potential guardians against genomic instability and tumorigenesis induced by ultraviolet photoproducts. J Invest Dermatol 2003; 121:435-440.
28. Maeda T, Chua PP, Chong MT, et al. Nucleotide excision repair genes are upregulated by low-dose artificial ultraviolet B: evidence of a photoprotective SOS response?. J Invest Dermatol 2001; 117:1490-1497.
29. Hildesheim J, Bulavin DV, Anver MR, et al. Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53. Cancer Res 2002; 62:7305-7315.
30. Maeda T, Hanna AN, Sim AB, et al. GADD45 regulates G2/M arrest, DNA repair, and cell death in keratinocytes following ultraviolet exposure. J Invest Dermatol 2002; 119:22-26.
31. Smith ML, Ford JM, Hollander MC, et al. p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes. Mol Cell Biol 2000; 20:3705-3714.
32. Takekawa M, Saito H. A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/ MEKK4 MAPKKK. Cell 1998; 95:521-530.
33. Jin S, Mazzacurati L, Zhu X, et al. Gadd45a contributes to p53 stabilization in response to DNA damage. Oncogene 2003; 22:8536-8540.
34. Menon EL, Perera R, Kuhn RJ, et al. Reactive oxygen species formation by UV-A irradiation of urocanic acid and the role of trace metals in this chemistry. Photochem Photobiol 2003; 78:567-575.
35. Ichiki H, Sakurada H, Kamo N, et al. Generation of active oxygens, cell deformation and membrane potential changes upon UV-B irradiation in human blood cells. Biol Pharm Bull 1994; 17:1065-1069.
36. Reid TM, Loeb LA. Tandem double CC→TT mutations are produced by reactive oxygen species. Proc Natl Acad Sci USA 1993; 90:3904-3907.
37. Zhang X, Rosenstein BS, Wang Y, et al. Identification of possible reactive oxygen species involved in ultraviolet radiation-induced oxidative DNA damage. Free Radic Biol Med 1997; 23:980-985.
38. Renzing J, Hansen S, Lane DP. Oxidative stress is involved in the UV activation of p53. J Cell Sci 1996; 109(Pt 5):1105-1112.
39. Vile GF. Active oxygen species mediate the solar ultraviolet radiation-dependent increase in the tumour suppressor protein p53 in human skin fibroblasts. FEBS Lett 1997; 412:70-74.
40. Devary Y, Gottlieb RA, Smeal T, et al. The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell 1992; 71:1081-1091.
41. Farber JL. Mechanisms of cell injury by activated oxygen species. Environ Health Perspect 1994; 102(Suppl 10):17-24.
42. Thorburn A. Death receptor-induced cell killing. Cell Signal 2004; 16:139-144.
43. Gutierrez-Steil C, Wrone-Smith T, Sun X, et al. Sunlight-induced basal cell carcinoma tumor cells and ultraviolet-B-irradiated psoriatic plaques express Fas ligand (CD95L). J Clin Invest 1998; 101:33-39.
44. Hill LL, Ouhtit A, Loughlin SM, et al. Fas ligand: a sensor for DNA damage critical in skin cancer etiology. Science 1999; 285:898-900.
45. Leverkus M, Yaar M, Gilchrest BA. Fas/Fas ligand interaction contributes to UV-induced apoptosis in human keratinocytes.. Exp Cell Res 1997; 232:255-262.
46. Faris M, Latinis KM, Kempiak SJ, et al. Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter. Mol Cell Biol 1998; 18:5414-5424.
47. Faris M, Kokot N, Latinis K, et al. The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by upregulating Fas ligand expression. J Immunol 1998; 160:134-144.
48. Kasibhatla S, Brunner T, Genestier L, et al. DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. Mol Cell 1998; 1:543-551.
49. Muller M, Wilder S, Bannasch D, et al. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 1998; 188:2033-2045.
50. Zhuang S, Kochevar IE. Ultraviolet A radiation induces rapid apoptosis of human leukemia cells by Fas ligand-independent activation of the Fas death pathways. Photochem Photobiol 2003; 78:61-67.
51. Aragane Y, Kulms D, Metze D, et al. Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L. J Cell Biol 1998; 140:171-182.
52. Lewis M, Tartaglia LA, Lee A, et al. Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc Natl Acad Sci USA 1991; 88:2830-2834.
53. Zhuang L, Wang B, Shinder GA, et al. TNF receptor p55 plays a pivotal role in murine keratinocyte apoptosis induced by ultraviolet B irradiation. J Immunol 1999; 162:1440-1447.
54. Kock A, Schwarz T, Kirnbauer R, et al. Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J Exp Med 1990; 172:1609-1614.
55. Bazzoni F, Kruys V, Shakhov A, et al. Analysis of tumor necrosis factor promoter responses to ultraviolet light. J Clin Invest 1994; 93:56-62.
56. Corsini E, Bruccoleri A, Marinovich M, et al. In vitro mechanism(s) of ultraviolet-induced tumor necrosis factor-alpha release in a human keratinocyte cell line. Photodermatol Photoimmunol Photomed 1995; 11:112-118.
57. Kibitel J, Hejmadi V, Alas L, et al. UV-DNA damage in mouse and human cells induces the expression of tumor necrosis factor alpha. Photochem Photobiol 1998; 67:541-546.
58. Leverkus M, Yaar M, Eller MS, et al. Post-transcriptional regulation of UV induced TNF-alpha expression. J Invest Dermatol 1998; 110:353-357.
59. Kossodo Sde, Cruz PD Jr, Dougherty I, et al. Expression of the tumor necrosis factor gene by dermal fibroblasts in response to ultraviolet irradiation or lipopolysaccharide. J Invest Dermatol 1995; 104:318-322.
60. Clingen PH, Berneburg M, Petit-Frere C, et al. Contrasting effects of an ultraviolet B and an ultraviolet A tanning lamp on interleukin-6, tumour necrosis factor-alpha and intercellular adhesion molecule-1 expression. Br J Dermatol 2001; 145:54-62.
61. Avalos-Diaz E, Alvarado-Flores E, Herrera-Esparza R. UV-A irradiation induces transcription of IL-6 and TNF alpha genes in human keratinocytes and dermal fibroblasts. Rev Rhum Engl Ed 1999; 66:13-19.
62. Sheikh MS, Antinore MJ, Huang Y, et al. Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1. Oncogene 1998; 17:2555-2563.
63. Pan G, ORourke K, Chinnaiyan AM, et al. The receptor for the cytotoxic ligand TRAIL. Science 1997; 276:111-113.
64. Sheridan JP, Marsters SA, Pitti RM, et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 1997; 277:818-821.
65. MacFarlane M, Ahmad M, Srinivasula SM, et al. Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL. J Biol Chem 1997; 272:25417-25420.
66. Walczak H, Degli-Esposti MA, Johnson RS, et al. TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. Embo J 1997; 16:5386-5397.
67. Wiley SR, Schooley K, Smolak PJ, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995; 3:673-682.
68. Ravi R, Bedi GC, Engstrom LW, et al. Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappa B. Nat Cell Biol 2001; 3:409-416.
69. Sheikh MS, Burns TF, Huang Y, et al. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. Cancer Res 1998; 58:1593-1598.
70. Guan B, Yue P, Clayman GL, et al. Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene. J Cell Physiol 2001; 188:98-105.
71. Godar DE, Lucas AD. Spectral dependence of UV-induced immediate and delayed apoptosis: the role of membrane and DNA damage. Photochem Photobiol 1995; 62:108-113.
72. Godar DE. Preprogrammed and programmed cell death mechanisms of apoptosis: UV-induced immediate and delayed apoptosis. Photochem Photobiol 1996; 63:825-830.
73. Nishigaki R, Mitani H, Tsuchida N, et al. Effect of cyclobutane pyrimidine dimers on apoptosis induced by different wavelengths of UV. Photochem Photobiol 1999; 70:228-235.