Independent contribution of three different pathways to ultraviolet-B-induced apoptosis

Biochemical Pharmacology

Volumn 64, Issue 5-6, 2002, Pages 837-841

  Kulms, Dagmar ^a   Schwarz, Thomas ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Apoptosis; Death receptor activation; DNA damage; Reactive oxygen species; Signal transduction; UVB radiation

Indexed keywords

CYTOCHROME C; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL SURFACE; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; MITOCHONDRION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ULTRAVIOLET RADIATION;

ANIMALS; APOPTOSIS; CELLS, CULTURED; DNA DAMAGE; HUMANS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; ULTRAVIOLET RAYS;

EID: 0036711208     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01146-2     Document Type: Article

References (40)

1. De Gruijl F.R., Sterenborg H.J., Forbes P.D., Davies R.E., Cole C., Kelfkens G., van Weelden H., Slaper H., van der Leun J.C. Wavelength dependence of skin cancer induction by ultraviolet irradiation of albino hairless mice. Cancer Res. 53:1995;53-60.
2. Beissert S., Schwarz T. Mechanisms involved in ultraviolet light-induced immunosuppression. J. Invest. Dermatol. Symp. Proc. 4:1999;61-64.
3. Fisher G.J., Wang Z.Q., Datta S.C., Varani J., Kang S., Voorhees J.J. Pathophysiology of premature skin aging induced by ultraviolet light. N. Engl. J. Med. 337:1997;1419-1428.
4. Petit-Frere C., Capulas E., Lowe J.E., Koulu L., Marttila R.J., Jaspers N.G., Clingen P.H., Green M.H., Arlett C.F. Ultraviolet-B-induced apoptosis and cytokine release in Xeroderma pigmentosum keratinocytes. J. Invest. Dermatol. 115:2000;687-693.
5. Patrick M.H. Studies on thymine-derived UVB photoproducts in DNA - I. Formation and biological role of pyrimidine adducts in DNA. Photochem. Photobiol. 25:1977;357-372.
6. De Laat W.L., Jaspers N.G., Hoeijmakers H.J. Molecular mechanism of nucleotide excision repair. Genes Dev. 13:1999;768-785.
7. Kraemer K.H. Sunlight and skin cancer: another link revealed. Proc. Natl. Acad. Sci. USA. 94:1997;1-14.
8. Yarosh D., Bucana C., Cox P., Alas L., Kibitel J., Kripke M.L. Localization of liposomes containing DNA repair enzyme in murine skin. J. Invest. Dermatol. 103:1994;461-468.
9. Kripke M.L., Cox P.A., Alas L.G., Yarosh D.B. Pyrimidine dimers in DNA initiate systemic immunosuppression in UV-irradiated mice. Proc. Natl. Acad. Sci. USA. 89:1992;7516-7520.
10. Nishigori C., Yarosh D.B., Ullrich S.E., Vink A.A., Bucana C.B., Roza L., Kripke M.L. Evidence that DNA damage triggers interleukin 10 cytokine production in UV-irradiated murine keratinocytes. Proc. Natl. Acad. Sci. USA. 93:1996;10354-10359.
11. Kibitel J., Hejmadi V., Alas L., O'Connor A., Sutherland B.M., Yarosh D. UV-DNA damage in mouse and human cells induces the expression of tumor necrosis factor alpha. Photochem. Photobiol. 67:1998;541-546.
12. Wolf P., Maier H., Mullegger R.R., Chadwick C.A., Hofmann-Wellenhof R., Soyer H.P., Hofer A., Smolle J., Horn M., Cerroni L., Yarosh D., Klein J., Bucana C., Dunner K. Jr., Potten C.S., Hönigsmann H., Kerl H., Kripke M.L. Topical treatment with liposomes containing T4 endunuclease V protects human skin in vivo from ultraviolet-induced upregulation of interleukin-10 and tumor necrosis factor-alpha. J. Invest. Dermatol. 114:2000;149-156.
13. Eker A.P., Kooiman P., Hessels J.K., Yasui A. DNA photoreactivating enzyme from the cyanobacterium Anacystis nidulans. J. Biol. Chem. 265:1990;8009-8015.
14. Stege H., Roza L., Vink A.A., Grewe M., Ruzicka T., Grether-Beck S., Krutmann J. Enzyme plus light therapy to repair DNA damage in ultraviolet-B-irradiated human skin. Proc. Natl. Acad. Sci. USA. 97:2000;1790-1795.
15. Yarosh D., Alas L.G., Yee V., Oberyszyn A., Kibitel J.T., Mitchell D., Rosenstein R., Spinowitz A., Citron M. Pyrimidine dimer removal enhanced by DNA repair liposomes reduces the incidence of UV skin cancer in mice. Cancer Res. 52:1992;4227-4231.
16. Murphy G., Young A.R., Wulf H.C., Kulms D., Schwarz T. The molecular determinants of sunburn cell formation. Exp. Dermatol. 10:2001;155-160.
17. Ziegler A., Jonason J.S., Leffel D.W., Simon J.A., Sharma H.W., Kimmelmann J., Remington L., Jacks T., Brash D.E. Sunburn and p53 in the onset of skin cancer. Nature. 372:1994;773-776.
18. Kulms D., Pöppelmann B., Yarosh D., Luger T.A., Krutmann J., Schwarz T. Nuclear and membrane effects contribute independently to the induction of apoptosis in human cells exposed to ultraviolet B radiation. Proc. Natl. Acad. Sci. USA. 96:1999;7974-7979.
19. Jonason A.S., Kunula S., Price G.J., Restifo R.J., Spinelli H.M., Persing J.A., Leffell D.J., Tarone R.E., Brash D.E. Frequent clones of p53 mutated keratinocytes in normal human skin. Proc. Natl. Acad. Sci. USA. 93:1996;14025-14029.
20. Ashkenazi A., Dixit V.M. Death receptors, signaling and modulation. Science. 281:1998;1305-1308.
21. Peter M.E., Krammer P.H. Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis. Curr. Opin. Immunol. 10:1998;545-551.
22. Salvesen G.S., Dixit V.M. Caspases: intracellular signaling by proteolysis. Cell. 91:1997;443-446.
23. Luo X., Budihardjo I., Zou H., Slaughter C., Wang X. Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell. 94:1998;481-490.
24. Hu Y., Benedict M.A., Ding L., Nunez G. Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis. EMBO J. 18:1999;3586-3595.
25. Aragane Y., Kulms D., Kothny G., Metze D., Pöppelmann B., Luger T.A., Schwarz T. Ultraviolet light induces apoptosis via direct activation of CD95 (FAS/APO-1) independently from its natural ligand CD95L. J. Cell Biol. 140:1998;171-182.
26. Rehemtulla A., Hamilton C.A., Chinnaiyan A.M., Dixit V.M. Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1). J. Biol. Chem. 272:1997;25783-25786.
27. Rosette C., Karin M. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science. 174:1996;1194-1197.
28. Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med. 3:1997;614-620.
29. Reed J.C. Double identity for proteins of the Bcl-2 family. Nature. 387:1997;773-776.
30. Liang Y.G., Jorgensen A.G., Kaestel C.G., Wiencke A.K., La Cour M.H., Ropke C.H., Nissen M.H. Bcl-2, Bax, and c-Fos expression correlates to RPE cell apoptosis induced by UV-light and daunorubicin. Curr. Eye Res. 20:2000;25-34.
31. Washio F., Ueda M., Ito A., Ichihashi M. Higher susceptibility to apoptosis following ultraviolet B radiation of Xeroderma pigmentosum fibroblasts is accompanied by upregulation of p53 and downregulation of bcl-2. Br. J. Dermatol. 140:1999;1031-1037.
32. Pourzand C., Tyrrell R.M. Apoptosis, the role of oxidative stress and the example of solar UV radiation. Photochem. Photobiol. 70:1999;380-390.
33. Tyrrell R.M. Ultraviolet radiation and free radical damage to skin. Biochem. Soc. Symp. 61:1995;47-53.
34. Tyrrell R.M. The molecular and cellular pathology of solar ultraviolet radiation. Mol. Aspects Med. 15:1994;1-77.
35. Black H.S. Potential involvement of free radical reactions in ultraviolet light-mediated cutaneous damage. Photochem. Photobiol. 46:1987;213-221.
36. Black H.S., Lambert C.R. Radical reactions of carotenoids and potential influence on UV carcinogenesis. Curr. Probl. Dermatol. 29:2001;140-156.
37. Bongarzone E.R., Pasquini J.M., Soto E.F. Oxidative damage to proteins and lipids of CNS myelin produced by in vitro generated reactive oxygen species. J. Neurosci. Res. 41:1995;213-221.
38. De Kok T.M.C.M., ten Vaarwerk F., Zwingmann I., van Maanen J.M.S., Kleinjans J.C.S. Peroxidation of linoleic, arachidonic and oleic acid in relation to the induction of oxidative DNA damage and cytogenetic effects. Carcinogenesis. 15:1994;1399-1404.
39. Farber J.L. Mechanism of cell injury by activated oxygen species. Environ. Health Perspect. 102:1994;17-24.
40. Kulms D, Zeise E, Pöppelmann B, Schwarz T. DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way. Oncogene 2002; in press.