Optimized vaccination regimen linked to exhaustive screening approaches identifies 2 novel HLA-B7 restricted epitopes within hepatitis C virus NS3 protein

Microbes and Infection

Volumn 8, Issue 9-10, 2006, Pages 2432-2441

  Martin, Perrine ^a,b   Parroche, Peggy ^a,b   Pajot, Anthony ^c   Chatel, Laurence ^a,b   Barreto, Caroline ^d   Touat, Leila ^a,b   Dubois, Valérie ^e   Rohrlich, Pierre Simon ^c   Bain, Christine ^a,b   Trépo, Christian ^f   Negro, Francesco ^g   Inchauspé, Geneviève ^a,b   Fournillier, Anne ^a,b  

^a IFR 128 BioSciences Lyon Gerland   (France)

^b BIOMÉRIEUX   (France)

^c INSTITUT PASTEUR   (France)

^d INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^e ETABLISSEMENT FRANÇAIS DU SANG   (France)

^f HÔTEL DIEU   (France)

^g Hôpital Cantonal   (Switzerland)

Author keywords

Cytolytic activity; Hepatitis C virus; HLA B7 Transgenic mice; IFN producing cells; Non structural 3 protein; T cell epitope

Indexed keywords

EPITOPE; GAMMA INTERFERON; HLA B7 ANTIGEN; INTERLEUKIN 10; LSP 10; NONSTRUCTURAL PROTEIN 3; PEPTIDE; UNCLASSIFIED DRUG; WPA 10;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; HEPATITIS C VIRUS; IMMUNIZATION; IMMUNOGENICITY; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE; TRANSGENIC MOUSE; VACCINATION;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CONSERVED SEQUENCE; EPITOPE MAPPING; EPITOPES, T-LYMPHOCYTE; HEPACIVIRUS; HEPATITIS C; HLA-B ANTIGENS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; T-LYMPHOCYTES, CYTOTOXIC; VACCINATION; VIRAL HEPATITIS VACCINES; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS; MUS MUSCULUS;

EID: 33749332391     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2006.05.006     Document Type: Article

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