The Effect of the AMPA/Kainate Receptor Antagonist LY293558 in a Rat Model of Postoperative Pain

Journal of Pain

Volumn 7, Issue 10, 2006, Pages 768-777

  Lee, Hae Jin ^a   Pogatzki Zahn, Esther M ^a,b   Brennan, Timothy J ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Glutamate; hyperalgesia; incision; nonNMDA

Indexed keywords

AMPA RECEPTOR ANTAGONIST; DECAHYDRO 6 [2 (1H TETRAZOL 5 YL)ETHYL] 3 ISOQUINOLINECARBOXYLIC ACID; KAINIC ACID RECEPTOR ANTAGONIST;

ANALGESIC ACTIVITY; ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; EXPERIMENTAL MODEL; HYPERALGESIA; LEG MOVEMENT; LOCAL ANESTHESIA; MALE; MECHANICAL STIMULATION; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; NOCICEPTION; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN ASSESSMENT; PAIN THRESHOLD; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; RAT; RAT STRAIN; SENSITIVITY ANALYSIS; SKIN INCISION; STIMULUS RESPONSE; TASK PERFORMANCE; TREATMENT RESPONSE; WITHDRAWAL REFLEX;

AFFERENT PATHWAYS; ANALGESICS; ANIMALS; CARBOXYLIC ACIDS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; HYPERALGESIA; INJECTIONS, INTRAPERITONEAL; INJECTIONS, SPINAL; INJECTIONS, SUBCUTANEOUS; ISOQUINOLINES; MALE; NOCICEPTORS; PAIN MEASUREMENT; PAIN THRESHOLD; PAIN, POSTOPERATIVE; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; TETRAZOLES; TREATMENT OUTCOME;

EID: 33749047667     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2006.03.010     Document Type: Article

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