Effects of NMDA and non-NMDA ionotropic glutamate receptor antagonists on the development and maintenance of hyperalgesia induced by repeated intramuscular injection of acidic saline

Pain

Volumn 98, Issue 1-2, 2002, Pages 69-78

  Skyba, D A ^a   King, E W ^a   Sluka, K A ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Acid; AMPA; Chronic; Glutamate; Kainate; Muscle; Pain

Indexed keywords

1,2,3,4 TETRAHYDRO 6 NITRO 2,3 DIOXO[F]QUINOXALINE 7 SULFONAMIDE; 2 AMINO 5 PHOSPHONOVALERIC ACID; IONOTROPIC RECEPTOR; IONOTROPIC RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; HYPERALGESIA; MALE; NONHUMAN; PAIN THRESHOLD; PH; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN;

2-AMINO-5-PHOSPHONOVALERATE; ACIDS; ANIMALS; DRUG ADMINISTRATION SCHEDULE; DRUG COMBINATIONS; EXCITATORY AMINO ACID ANTAGONISTS; HYPERALGESIA; INJECTIONS, INTRAMUSCULAR; MALE; MOTOR ACTIVITY; MUSCLE, SKELETAL; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; REFLEX; SODIUM CHLORIDE;

EID: 0036302824     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(01)00471-7     Document Type: Article

References (67)

1. Response of chronic neuropathic pain syndromes to ketamin: A preliminary study
2. Modulation of AMPA receptor unitary conductance by synaptic activity
3. Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit
4. Enhancement of the N-methyl-D-aspartate response in spinal dorsal horn neurons by cAMP-dependent protein kinase
5. Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat
6. Enhanced responses of rat dorsal horn neurons after UV irradiation of the hindpaw; Roles of the NMDA receptor
7. 2+ block of NMDA-receptor channels as a mechanism of modulation
8. The contribution of excitatory amino acids to central sensitization and persistent nociception after formalin-induced tissue injury
9. The utility of excitatory amino acid (EAA) antagonists as analgesic agents. I. Comparison of the antinociceptive activity of various classes of EAA antagonists in mechanical, thermal and chemical nociceptive tests
10. Intracellular messengers contributing to persistent nociception and hyperalgesia induced by L-glutamate and substance P in the rat formalin pain model
11. Contribution of central plasticity to pathological pain: Review of clinical and experimental evidence
12. The role of ionotropic and metabotropic glutamate receptors in persistent nociception
13. Excitatory amino acids in synaptic transmission in the schaffer collateral-commissural pathway of the rat hippocampus
14. Evidence for involvement of N-methyl-D-aspartate receptors in 'windup' of class 2 neurones in the dorsal horn of the rat
15. 2+/calmodulin-kinase II enhances channel conductance of a-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors
16. Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurons following C fibre stimulation
17. The role of NMDA and non-NMDA excitatory amino-acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli
18. Relief of post-herpetic neuralgia with N-methyl-D-aspartic acid receptor ketamine: A double-blind, cross-over comparison with morphine and placebo
19. Continuous subcutaneous administration of N-methyl-D-apartic acid (NMDA) receptor antagonist ketamine in the treatment of post-herpetic neuralgia
20. NMDA receptor blockade in chronic neuropathic pain: A comparison of ketamine and magnesium chloride
21. Multiple effects of phorbol esters in the rat spinal dorsal horn
22. Effects of 2-amino-3-hydroxy-5-methyl-4-isoxazole-proprionic acid/kainite antagonist LY293558 on spontaneous and evoked postoperative pain
23. Effect of varying frequency, intensity, and pulse duration of transcutaneous electrical nerve stimulation on primary hyperalgesia in inflamed rats
24. Ketamine reduces muscle pain, temporal summation, and referred pain in fibromyalgia patients
25. Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat
26. 2+ permeability of KA-AMPA-gated glutamate receptor channels depends on subunit composition
27. Alpha subunit of calcium/calmodulin-dependent protein kinase enhances excitatory amino acid and synaptic responses of rat spinal dorsal horn neurons
28. Possible role of protein kinase C in the sensitization of primate spinothalamic tract neurons
29. Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of camp-dependent protein kinase
30. Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy
31. Intrathecal treatment with dextrorphan or ketamine potently reduces pain related behaviors in a rat model of peripheral mononeuropathy
32. Intravenous infusion of the NMDA antagonist, Ketamine, in chronic posttraumatic pain with allodynia: A double-blind comparison of alfentanil and placebo
33. Fibromyalgia and myofascial pain syndromes
34. Evidence for a role of protein kinase C in the sustained activation of rat dorsal horn neurons evoked by cutaneous mustard oil application
35. N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rats knee joint
36. Effect of pretreatment with intrathecal excitatory amino acid receptor antagonists on the development of pain behavior caused by plantar incision
37. Lumber catheterization of the subarachnoid space with a 32-gauge polyurethane catheter in the rat
38. Prolonged analgesic effect of ketamine, N-methyl-D-apartate receptor inhibitor, in patients with chronic pain
39. NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpaw
40. The intrathecal administration of excitatory amino-acid receptor antagonists selectively attenuated carrageenan-induces behavioral hyperalgesia in rats
41. The effects of a noncompetitive NMDA receptor antagonist, mk-801, on behavioral hyperalgesia and dorsal horn neuronal-activity in rats with unilateral inflammation
42. Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit
43. AMPA/kainite antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans
44. Selective excitation of neurons in the mammalian spinal dorsal horn by aspartate and glutamate in vitro: Correlation with location and excitatory input
45. Comparison of primary afferent and glutamate excitation of neurons in the mammalian spinal dorsal horn
46. The role of the cyclic AMP transduction cascade in mechanical allodynia and hyperalgesia induced by intradermal injection of capsaicin in rats
47. An experimental arthritis in rat: Dorsal horn aspartate and glutamate increases
48. Spinal cord amino acid release and content in an arthritis model: The effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists
49. Centrally administered non-NMDA but not NMDA receptor antagonists block peripheral knee joint inflammation
50. The effects of G-protein and protein kinase inhibitors on the behavioral responses of rats to intradermal injection of capsaicin
51. Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on spinal release of amino acid after development of acute arthritis in rats
52. Reduction in joint swelling and hyperalgesia following post treatment with a non-NMDA glutamate receptor antagonist
53. Inhibitors of G-proteins and protein kinases reduce the sensitization to mechanical stimulation and the desensitization to heat of spinothalamic tract neurons induced by intradermal injection of capsaicin in the primate
54. Unilateral intramuscular injections of acidic saline produce a bilateral, long-lasting hyperalgesia
55. Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine
56. Fibromyalgia - are there different mechanisms in the processing of pain? A double blind crossover comparison of analgesic drugs
57. Neural changes in acute arthritis in monkeys. IV. Time course of amino acid release into the lumbar dorsal horn
58. 2+ permeable AMPA receptor antagonist
59. 2+ permeable non-NMDA receptor antagonists
60. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; Implications for the treatment of post-injury pain hypersensitivity states
61. Comparison of the antinociceptive effects of pre- and posttreatment with intrathecal morphine and MK801, and NMDA antagonist, on the formalin test in the rat
62. The economic costs and social and psychological impact of musculoskeletal conditions
63. Amino acid-mediated EPSPs at primary afferent synapses with substantia gelatinosa neurones in the rat spinal cord
64. Lack of effect of intrathecally administered N-methyl-D-apartate receptor antagonists in a rat model of postoperative pain
65. Intrathecal non-NMDA excitatory amino acid receptor antagonists inhibit pain behaviors in a rat model of postoperative pain
66. Enhanced phosphorylation of NMDA receptor 1 subunits in spinal cord dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats