메뉴 건너뛰기




Volumn 1072, Issue , 2006, Pages 365-378

Inflammatory bowel disease: Pandora's box, present and future

Author keywords

Bacteria; Biologicals; Etiology; Inflammatory bowel disease; Pathophysiology; Probiotics

Indexed keywords

AZATHIOPRINE; BUDESONIDE; GLUCOCORTICOID; INFLIXIMAB; MERCAPTOPURINE; MESALAZINE; PREBIOTIC AGENT; PREDNISONE; PROBIOTIC AGENT; SALAZOSULFAPYRIDINE; STEROID;

EID: 33749013297     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1326.026     Document Type: Conference Paper
Times cited : (17)

References (48)
  • 1
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • OGURA, Y. et al. 2001. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411: 603-606.
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1
  • 2
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • HUGOT, J.P. et al. 2001. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411: 599-603.
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1
  • 3
    • 0035897904 scopus 로고    scopus 로고
    • Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
    • HAMPE, J. et al. 2001. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 357: 1925-1928.
    • (2001) Lancet , vol.357 , pp. 1925-1928
    • Hampe, J.1
  • 4
    • 4444253690 scopus 로고    scopus 로고
    • NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
    • WATANABE, T. et al. 2004. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat. Immunol. 5: 800-808.
    • (2004) Nat. Immunol. , vol.5 , pp. 800-808
    • Watanabe, T.1
  • 5
    • 7244257312 scopus 로고    scopus 로고
    • NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression
    • WEHKAMP, J. et al. 2004. NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression. Gut 53: 1658-1664.
    • (2004) Gut , vol.53 , pp. 1658-1664
    • Wehkamp, J.1
  • 6
    • 0035793372 scopus 로고    scopus 로고
    • Molecular analysis of commensal host-microbial relationships in the intestine
    • HOOPER, L.V et al. 2001. Molecular analysis of commensal host-microbial relationships in the intestine. Science 29: 881-884.
    • (2001) Science , vol.29 , pp. 881-884
    • Hooper, L.V.1
  • 7
    • 3242771408 scopus 로고    scopus 로고
    • Both, donor and recipient NOD 2/CARD15 mutations associate with transplant-related mortality and gastrointestinal GvHD following allogeneic stem cell transplantation
    • HOLLER, E. et al. 2004. Both, donor and recipient NOD 2/CARD15 mutations associate with transplant-related mortality and gastrointestinal GvHD following allogeneic stem cell transplantation. Blood 104: 889-894.
    • (2004) Blood , vol.104 , pp. 889-894
    • Holler, E.1
  • 8
    • 0028217167 scopus 로고
    • Inflammatory bowel disease and domestic hygiene in infancy
    • GENT, A.E. et al. 1994. Inflammatory bowel disease and domestic hygiene in infancy. Lancet 343: 766-767.
    • (1994) Lancet , vol.343 , pp. 766-767
    • Gent, A.E.1
  • 9
    • 2442585704 scopus 로고    scopus 로고
    • Functional variants of OCTN cation transporter genes are associated with Crohn disease
    • PELTEKOVA, V.D. et al. 2004. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat. Genet. 36: 471-475.
    • (2004) Nat. Genet. , vol.36 , pp. 471-475
    • Peltekova, V.D.1
  • 10
    • 2442519456 scopus 로고    scopus 로고
    • Genetic variation in DLG5 is associated with inflammatory bowel disease
    • STOLL, M. et al. 2004. Genetic variation in DLG5 is associated with inflammatory bowel disease. Nat. Genet. 36: 476-480.
    • (2004) Nat. Genet. , vol.36 , pp. 476-480
    • Stoll, M.1
  • 11
    • 0037223561 scopus 로고    scopus 로고
    • Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis
    • SCHWAB, M. et al. 2003. Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis. Gastroenterology 124: 26-33.
    • (2003) Gastroenterology , vol.124 , pp. 26-33
    • Schwab, M.1
  • 12
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
    • PASARE, C. & R. MEDZHITOV. 2003. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 299: 1033-1036.
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 13
    • 25444452680 scopus 로고    scopus 로고
    • In vivo CpG DNA/toll like receptor 9 interection induces regulatory properties in CD4+CD62L+ T cells which prevent intestinal inflammation in the SCID transfer model of colitis
    • OBERMEIER, F. et al. 2005. In vivo CpG DNA/toll like receptor 9 interection induces regulatory properties in CD4+CD62L+ T cells which prevent intestinal inflammation in the SCID transfer model of colitis. GUT 54: 1428-1436.
    • (2005) GUT , vol.54 , pp. 1428-1436
    • Obermeier, F.1
  • 14
    • 0002063230 scopus 로고    scopus 로고
    • A simple classification of Crohn's disease
    • GASCHÉ, C. et al. 2000. A Simple Classification of Crohn's Disease. Inflamm. Bowel. Dis. 6: 8-15.
    • (2000) Inflamm. Bowel. Dis. , vol.6 , pp. 8-15
    • Gasché, C.1
  • 15
    • 0034906019 scopus 로고    scopus 로고
    • Autoimmunity and apoptosis: The Crohn's connection
    • BEUTLER, B. 2001. Autoimmunity and apoptosis: the Crohn's connection. Immunity 15: 5-14.
    • (2001) Immunity , vol.15 , pp. 5-14
    • Beutler, B.1
  • 16
    • 0142187683 scopus 로고    scopus 로고
    • Biological therapies in IBD-anti TNFα and others
    • SCHÖLMERICH, J. & G. HUBER. 2003. Biological therapies in IBD-anti TNFα and others. Dig. Dis. 21: 180-191.
    • (2003) Dig. Dis. , vol.21 , pp. 180-191
    • Schölmerich, J.1    Huber, G.2
  • 17
    • 0027478285 scopus 로고
    • Meta-analysis of the effectiveness of current drug therapy of ulcerative colitis
    • KORNBLUTH, A.A. et al. 1993. Meta-analysis of the effectiveness of current drug therapy of ulcerative colitis. J. Clin. Gastroenterol. 16: 215-218.
    • (1993) J. Clin. Gastroenterol. , vol.16 , pp. 215-218
    • Kornbluth, A.A.1
  • 18
    • 0033022146 scopus 로고    scopus 로고
    • Clinical course and costs of care for Crohn's disease: Markov model analysis of a population-based cohort
    • SILVERSTEIN, M.D. et al. 1999. Clinical course and costs of care for Crohn's disease: Markov model analysis of a population-based cohort. Gastroenterology 117: 49-57.
    • (1999) Gastroenterology , vol.117 , pp. 49-57
    • Silverstein, M.D.1
  • 19
    • 0034903792 scopus 로고    scopus 로고
    • The natural history of corticosteroid therapy for inflammatory bowel disease: A population-based study
    • FAUBION, W.A. Jr. et al. 2001. The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study. Gastroenterology 121: 255-260.
    • (2001) Gastroenterology , vol.121 , pp. 255-260
    • Faubion Jr., W.A.1
  • 20
    • 0345655293 scopus 로고    scopus 로고
    • Survival and cause-specific mortality in ulcerative colitis: Follow-up of a population-based cohort in Copenhagen county
    • WINTHER, K.V. et al. 2003. Survival and cause-specific mortality in ulcerative colitis: follow-up of a population-based cohort in Copenhagen county. Gastroenterology 125: 1576-1582.
    • (2003) Gastroenterology , vol.125 , pp. 1576-1582
    • Winther, K.V.1
  • 21
    • 0035087887 scopus 로고    scopus 로고
    • Smoking cessation and the course of Crohn's disease: An intervention study
    • COSNES, J. et al. 2001. Smoking cessation and the course of Crohn's disease: an intervention study. Gastroenterology 120: 1093-1099.
    • (2001) Gastroenterology , vol.120 , pp. 1093-1099
    • Cosnes, J.1
  • 22
    • 0036207249 scopus 로고    scopus 로고
    • The natural history of fistulizing Crohn's disease in Olmsted County, Minnesota
    • SCHWARTZ, D.A. et al. 2002. The natural history of fistulizing Crohn's disease in Olmsted County, Minnesota. Gastroenterology 122: 875-880.
    • (2002) Gastroenterology , vol.122 , pp. 875-880
    • Schwartz, D.A.1
  • 23
    • 21344448621 scopus 로고    scopus 로고
    • Are patients with inflammatory bowel disease receiving optimal care?
    • REDDY, S.I. et al. 2005. Are patients with inflammatory bowel disease receiving optimal care? Am. J. Gastroenterol. 100: 1357-1361.
    • (2005) Am. J. Gastroenterol. , vol.100 , pp. 1357-1361
    • Reddy, S.I.1
  • 24
    • 21044433011 scopus 로고    scopus 로고
    • Combined oral and enema treatment with Pentasa (mesalazine) is superior to oral therapy alone in patients with extensive mild/moderate active ulcerative colitis: A randomised, double blind, placebo controlled study
    • MARTEAU, P. et al. 2005. Combined oral and enema treatment with Pentasa (mesalazine) is superior to oral therapy alone in patients with extensive mild/moderate active ulcerative colitis: a randomised, double blind, placebo controlled study. Gut 54: 960-965.
    • (2005) Gut , vol.54 , pp. 960-965
    • Marteau, P.1
  • 25
    • 0028790186 scopus 로고
    • A controlled double blind study of azathioprine in the management of Crohn's disease
    • CANDY, S. et al. 1995. A controlled double blind study of azathioprine in the management of Crohn's disease. Gut 37: 674-678.
    • (1995) Gut , vol.37 , pp. 674-678
    • Candy, S.1
  • 26
    • 0037018761 scopus 로고    scopus 로고
    • Maintenance infliximab for Crohn's disease: The ACCENT I randomised trial
    • HANAUER, S.B. et al. 2002. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet 359: 1541-1549.
    • (2002) Lancet , vol.359 , pp. 1541-1549
    • Hanauer, S.B.1
  • 27
    • 5044235159 scopus 로고    scopus 로고
    • Long-term treatment of rectovaginal fistulas in Crohn's disease: Response to infliximab in the ACCENT II study
    • SANDS, B.E. et al. 2004. Long-term treatment of rectovaginal fistulas in Crohn's disease: response to infliximab in the ACCENT II study. Clin. Gastroenterol. Hepatol. 2: 912-920.
    • (2004) Clin. Gastroenterol. Hepatol. , vol.2 , pp. 912-920
    • Sands, B.E.1
  • 28
    • 20444432816 scopus 로고    scopus 로고
    • A randomized placebo-controlled trial of infliximab therapy for active ulcerative colitis: Act I trial
    • RUTGEERTS, P. et al. 2005. A randomized placebo-controlled trial of infliximab therapy for active ulcerative colitis: Act I trial. Gastroenterology 128: A105.
    • (2005) Gastroenterology , vol.128
    • Rutgeerts, P.1
  • 29
    • 20444487429 scopus 로고    scopus 로고
    • Infliximab induction and maintenance therapy for ulcerative colitis: The Act 2 trial
    • SANDBORN, W.J. et al. 2005. Infliximab induction and maintenance therapy for ulcerative colitis: the Act 2 trial. Gastroenterology 128: A104.
    • (2005) Gastroenterology , vol.128
    • Sandborn, W.J.1
  • 30
    • 20444479336 scopus 로고    scopus 로고
    • Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: A randomized, placebo-controlled study
    • JÄRNEROT, G. et al. 2005. Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: a randomized, placebo-controlled study. Gastroenterology 128: 1805-1811.
    • (2005) Gastroenterology , vol.128 , pp. 1805-1811
    • Järnerot, G.1
  • 31
    • 0012682329 scopus 로고    scopus 로고
    • CDP870, a humanized anti-TNF antibody fragment, induces clinical response with remission in patients with active Crohn's disease
    • SCHREIBER, S. et al. 2003. CDP870, a humanized anti-TNF antibody fragment, induces clinical response with remission in patients with active Crohn's disease. Gastroenterology 125: 606.
    • (2003) Gastroenterology , vol.125 , pp. 606
    • Schreiber, S.1
  • 32
    • 0037483705 scopus 로고    scopus 로고
    • Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis
    • SINHA, A. et al. 2003. Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis. N. Engl. J. Med. 349: 350-357.
    • (2003) N. Engl. J. Med. , vol.349 , pp. 350-357
    • Sinha, A.1
  • 33
    • 0000415874 scopus 로고    scopus 로고
    • Immunostimulation in Crohn's disease: Retreatment and maintenance therapy with GM-CSF
    • KORZENIK, J., A. PITTLER & B. DIECKGRAEFE. 2002. Immunostimulation in Crohn's disease: retreatment and maintenance therapy with GM-CSF. Gastroenterology 122: A432-A433.
    • (2002) Gastroenterology , vol.122
    • Korzenik, J.1    Pittler, A.2    Dieckgraefe, B.3
  • 35
    • 29444445452 scopus 로고    scopus 로고
    • Management of recent onset Crohn's disease: A controlled, randomized trial comparing step-up and top-down therapy
    • HOMMES, D. et al. 2005. Management of recent onset Crohn's disease: a controlled, randomized trial comparing step-up and top-down therapy. Gastroenterology 129: 371.
    • (2005) Gastroenterology , vol.129 , pp. 371
    • Hommes, D.1
  • 36
    • 0242606051 scopus 로고    scopus 로고
    • Contrasting activity of cytosine-guanosin dinucleotide oligonucleotides in mice with experimental colitis
    • OBERMEIER, F. et al. 2003. Contrasting activity of cytosine-guanosin dinucleotide oligonucleotides in mice with experimental colitis. Clin. Exp. Immunol. 134: 217-224.
    • (2003) Clin. Exp. Immunol. , vol.134 , pp. 217-224
    • Obermeier, F.1
  • 37
    • 0142187692 scopus 로고    scopus 로고
    • Rationale for probiotic and antibiotic strategies in inflammatory bowel diseases
    • SCHULTZ, M., J. SCHÖLMERICH & H.C. RATH. 2003. Rationale for probiotic and antibiotic strategies in inflammatory bowel diseases. Dig. Dis. 21: 105-128.
    • (2003) Dig. Dis. , vol.21 , pp. 105-128
    • Schultz, M.1    Schölmerich, J.2    Rath, H.C.3
  • 38
    • 4644239296 scopus 로고    scopus 로고
    • Maintaining remission of ulcerative colitis with the probiotic E. coli Nissle 1917 is as effective as with standard mesalazine
    • KRUIS, W. et al. 2004. Maintaining remission of ulcerative colitis with the probiotic E. coli Nissle 1917 is as effective as with standard mesalazine. Gut 53: 1617-1623.
    • (2004) Gut , vol.53 , pp. 1617-1623
    • Kruis, W.1
  • 39
    • 0033860601 scopus 로고    scopus 로고
    • Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis. A double-blind, placebo-controlled trial
    • GIONCHETTI, P. et al. 2000. Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis. A double-blind, placebo-controlled trial. Gastroenterology 119: 305-309.
    • (2000) Gastroenterology , vol.119 , pp. 305-309
    • Gionchetti, P.1
  • 40
    • 0038185270 scopus 로고    scopus 로고
    • Prophylaxis of pouchitis onset with probiotic therapy: A double-blind, placebo-controlled trial
    • GIONCHETTI, P. et al. 2003. Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. Gastroenterology 124: 1202-1209.
    • (2003) Gastroenterology , vol.124 , pp. 1202-1209
    • Gionchetti, P.1
  • 41
    • 0036716855 scopus 로고    scopus 로고
    • Ineffectiveness of probiotics in preventing recurrence after curative resection for Crohn's disease: A randomized controlled trial with Lactobacillus GG
    • PRANTERA, C. et al. 2002. Ineffectiveness of probiotics in preventing recurrence after curative resection for Crohn's disease: a randomized controlled trial with Lactobacillus GG. Gut 51: 405-409.
    • (2002) Gut , vol.51 , pp. 405-409
    • Prantera, C.1
  • 42
    • 33646756180 scopus 로고    scopus 로고
    • Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn's disease - A randomized, double-blind, placebo-controlled GETAID trial
    • MARTEAU, P. et al. 2006. Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn's disease-a randomized, double-blind, placebo-controlled GETAID trial. Gut 55: 842-847.
    • (2006) Gut , vol.55 , pp. 842-847
    • Marteau, P.1
  • 43
    • 22744438084 scopus 로고    scopus 로고
    • VSL#3 probiotic-mixture induces remission in patients with active ulcerative colitis
    • BIBILONI, R. et al. 2005. VSL#3 probiotic-mixture induces remission in patients with active ulcerative colitis. Am. J. Gastroenterol. 100: 1539-1546.
    • (2005) Am. J. Gastroenterol. , vol.100 , pp. 1539-1546
    • Bibiloni, R.1
  • 44
    • 33144470875 scopus 로고    scopus 로고
    • Clinical, microbiological and immunological effects of fructo-oligosaccharide in patients with Crohn's disease
    • LINDSAY, J.O. et al. 2006. Clinical, microbiological and immunological effects of fructo-oligosaccharide in patients with Crohn's disease. Gut, 348-355.
    • (2006) Gut , pp. 348-355
    • Lindsay, J.O.1
  • 45
    • 21044457089 scopus 로고    scopus 로고
    • Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis
    • STREMMEL, W. et al. 2005. Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis. Gut 54: 966-971.
    • (2005) Gut , vol.54 , pp. 966-971
    • Stremmel, W.1
  • 46
    • 10844224526 scopus 로고    scopus 로고
    • Trichuris suis therapy in Crohn's disease
    • SUMMERS, R.W. et al. 2005. Trichuris suis therapy in Crohn's disease. Gut 54: 87-90.
    • (2005) Gut , vol.54 , pp. 87-90
    • Summers, R.W.1
  • 47
    • 17144402166 scopus 로고    scopus 로고
    • Trichuris suis therapy for active ulcerative colitis: A randomized controlled trial
    • SUMMERS, R.W. et al. 2005. Trichuris suis therapy for active ulcerative colitis: a randomized controlled trial. Gastroenterology 128: 825-832.
    • (2005) Gastroenterology , vol.128 , pp. 825-832
    • Summers, R.W.1
  • 48
    • 33747789607 scopus 로고    scopus 로고
    • Survival and cause-specific mortality in patients with inflammatory bowel disease: A long-term outcome study in Olmsted County, Minnesota, 1940-2004
    • doi: 10.1136/gut.2005.079350
    • JESS, T. et al. 2006. Survival and cause-specific mortality in patients with inflammatory bowel disease: a long-term outcome study in Olmsted County, Minnesota, 1940-2004. Gut, doi: 10.1136/gut.2005.079350.
    • (2006) Gut
    • Jess, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.