메뉴 건너뛰기




Volumn 449, Issue 4, 2006, Pages 421-427

Immunohistochemical detection of bombesin receptor subtypes GRP-R and BRS-3 in human tumors using novel antipeptide antibodies

Author keywords

Antibody; Bombesin; Bombesin receptor; BRS 3; GRP R; Immunocytochemistry; Neoplasm; Western blot

Indexed keywords

BOMBESIN; BOMBESIN RECEPTOR; BOMBESIN RECEPTOR SUBTYPE 3; FORMALDEHYDE; G PROTEIN COUPLED RECEPTOR; GASTRIN RELEASING PEPTIDE PREFERRING BOMBESIN RECEPTOR; PARAFFIN; PEPTIDE ANTIBODY; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

EID: 33748987928     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-006-0265-7     Document Type: Article
Times cited : (26)

References (42)
  • 1
    • 0015224130 scopus 로고
    • Isolation and structure of bombesin and alytesin, 2 analogous active peptides from the skin of the European amphibians Bombina and Alytes
    • Anastasi A, Erspamer V, Bucci M (1971) Isolation and structure of bombesin and alytesin, 2 analogous active peptides from the skin of the European amphibians Bombina and Alytes. Experientia 27:166-167
    • (1971) Experientia , vol.27 , pp. 166-167
    • Anastasi, A.1    Erspamer, V.2    Bucci, M.3
  • 2
    • 0032423523 scopus 로고    scopus 로고
    • Bombesin stimulates in vitro growth of human breast cancer independent of estrogen receptors status
    • Bold RJ, Ishizuka J, Yao CZ, Townsend CM Jr, Thompson JC (1998) Bombesin stimulates in vitro growth of human breast cancer independent of estrogen receptors status. Anticancer Res 18:4051-4056
    • (1998) Anticancer Res , vol.18 , pp. 4051-4056
    • Bold, R.J.1    Ishizuka, J.2    Yao, C.Z.3    Townsend Jr., C.M.4    Thompson, J.C.5
  • 5
    • 0032895181 scopus 로고    scopus 로고
    • Aberrant expression of gastrin-releasing peptide and its receptor by well-differentiated colon cancers in humans
    • Carroll RE, Matkowskyj KA, Chakrabarti S, McDonald TJ, Benya RV (1999) Aberrant expression of gastrin-releasing peptide and its receptor by well-differentiated colon cancers in humans. Am J Physiol 276:G655-665
    • (1999) Am J Physiol , vol.276
    • Carroll, R.E.1    Matkowskyj, K.A.2    Chakrabarti, S.3    McDonald, T.J.4    Benya, R.V.5
  • 6
    • 0033851081 scopus 로고    scopus 로고
    • Characterization of gastrin-releasing peptide and its receptor aberrantly expressed by human colon cancer cell lines
    • Carroll RE, Ostrovskiy D, Lee S, Danilkovich A, Benya RV (2000) Characterization of gastrin-releasing peptide and its receptor aberrantly expressed by human colon cancer cell lines. Mol Pharmacol 58:601-607
    • (2000) Mol Pharmacol , vol.58 , pp. 601-607
    • Carroll, R.E.1    Ostrovskiy, D.2    Lee, S.3    Danilkovich, A.4    Benya, R.V.5
  • 7
    • 0033986991 scopus 로고    scopus 로고
    • Bombesin family receptor and ligand gene expression in human colorectal cancer and normal mucosa
    • Chave HS, Gough AC, Palmer K, Preston SR, Primrose JN (2000) Bombesin family receptor and ligand gene expression in human colorectal cancer and normal mucosa. Br J Cancer 82:124-130
    • (2000) Br J Cancer , vol.82 , pp. 124-130
    • Chave, H.S.1    Gough, A.C.2    Palmer, K.3    Preston, S.R.4    Primrose, J.N.5
  • 8
    • 16844372709 scopus 로고    scopus 로고
    • Effective inhibition of experimental human ovarian cancers with a targeted cytotoxic bombesin analogue AN-215
    • Engel JB, Keller G, Schally AV, Halmos G, Hammann B, Nagy A (2005) Effective inhibition of experimental human ovarian cancers with a targeted cytotoxic bombesin analogue AN-215. Clin Cancer Res 11:2408-2415
    • (2005) Clin Cancer Res , vol.11 , pp. 2408-2415
    • Engel, J.B.1    Keller, G.2    Schally, A.V.3    Halmos, G.4    Hammann, B.5    Nagy, A.6
  • 9
    • 29144509887 scopus 로고    scopus 로고
    • Targeted cytotoxic bombesin analog AN-215 effectively inhibits experimental human breast cancers with a low induction of multi-drug resistance proteins
    • Engel JB, Schally AV, Halmos G, Baker B, Nagy A, Keller G (2005) Targeted cytotoxic bombesin analog AN-215 effectively inhibits experimental human breast cancers with a low induction of multi-drug resistance proteins. Endocr Relat Cancer 12:999-1009
    • (2005) Endocr Relat Cancer , vol.12 , pp. 999-1009
    • Engel, J.B.1    Schally, A.V.2    Halmos, G.3    Baker, B.4    Nagy, A.5    Keller, G.6
  • 10
    • 0034534349 scopus 로고    scopus 로고
    • Bombesin receptors in distinct tissue compartments of human pancreatic diseases
    • Fleischmann A, Laderach U, Friess H, Buechler MW, Reubi JC (2000) Bombesin receptors in distinct tissue compartments of human pancreatic diseases. Lab Invest 80:1807-1817
    • (2000) Lab Invest , vol.80 , pp. 1807-1817
    • Fleischmann, A.1    Laderach, U.2    Friess, H.3    Buechler, M.W.4    Reubi, J.C.5
  • 11
    • 23844525378 scopus 로고    scopus 로고
    • Gastrinreleasing peptide receptors in normal and neoplastic human uterus: Involvement of multiple tissue compartments
    • Fleischmann A, Waser B, Gebbers JO, Reubi JC (2005) Gastrinreleasing peptide receptors in normal and neoplastic human uterus: involvement of multiple tissue compartments. J Clin Endocrinol Metab 90:4722-4729
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 4722-4729
    • Fleischmann, A.1    Waser, B.2    Gebbers, J.O.3    Reubi, J.C.4
  • 12
    • 0032804044 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptors in non-neoplastic and neoplastic human breast
    • Gugger M, Reubi JC (1999) Gastrin-releasing peptide receptors in non-neoplastic and neoplastic human breast. Am J Pathol 155:2067-2076
    • (1999) Am J Pathol , vol.155 , pp. 2067-2076
    • Gugger, M.1    Reubi, J.C.2
  • 13
    • 0034653403 scopus 로고    scopus 로고
    • Inhibition of growth of MDA-MB-468 estrogen-independent human breast carcinoma by bombesin/gastrin-releasing peptide antagonists RC-3095 and RC-3940-II
    • Kahan Z, Sun B, Schally AV, Arencibia JM, Cai RZ, Groot K, Halmos G (2000) Inhibition of growth of MDA-MB-468 estrogen-independent human breast carcinoma by bombesin/gastrin-releasing peptide antagonists RC-3095 and RC-3940-II. Cancer 88:1384-1392
    • (2000) Cancer , vol.88 , pp. 1384-1392
    • Kahan, Z.1    Sun, B.2    Schally, A.V.3    Arencibia, J.M.4    Cai, R.Z.5    Groot, K.6    Halmos, G.7
  • 14
    • 27644545827 scopus 로고    scopus 로고
    • Targeted chemotherapy with cytotoxic bombesin analogue AN-215 can overcome chemoresistance in experimental renal cell carcinomas
    • Keller G, Schally AV, Nagy A, Halmos G, Baker B, Engel JB (2005) Targeted chemotherapy with cytotoxic bombesin analogue AN-215 can overcome chemoresistance in experimental renal cell carcinomas. Cancer 104:2266-2274
    • (2005) Cancer , vol.104 , pp. 2266-2274
    • Keller, G.1    Schally, A.V.2    Nagy, A.3    Halmos, G.4    Baker, B.5    Engel, J.B.6
  • 15
    • 0032744924 scopus 로고    scopus 로고
    • Targeted cytotoxic analogue of bombesin/gastrin-releasing peptide inhibits the growth of H-69 human small-cell lung carcinoma in nude mice
    • Kiaris H, Schally AV, Nagy A, Sun B, Armatis P, Szepeshazi K (1999) Targeted cytotoxic analogue of bombesin/gastrin-releasing peptide inhibits the growth of H-69 human small-cell lung carcinoma in nude mice. Br J Cancer 81:966-971
    • (1999) Br J Cancer , vol.81 , pp. 966-971
    • Kiaris, H.1    Schally, A.V.2    Nagy, A.3    Sun, B.4    Armatis, P.5    Szepeshazi, K.6
  • 17
    • 0033104343 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptors in the human prostate: Relation to neoplastic transformation
    • Markwalder R, Reubi JC (1999) Gastrin-releasing peptide receptors in the human prostate: relation to neoplastic transformation. Cancer Res 59:1152-1159
    • (1999) Cancer Res , vol.59 , pp. 1152-1159
    • Markwalder, R.1    Reubi, J.C.2
  • 19
    • 0020558866 scopus 로고
    • Neuromedin B: A novel bombesin-like peptide identified in porcine spinal cord
    • Minamino N, Kangawa K, Matsuo H (1983) Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord. Biochem Biophys Res Commun 114:541-548
    • (1983) Biochem Biophys Res Commun , vol.114 , pp. 541-548
    • Minamino, N.1    Kangawa, K.2    Matsuo, H.3
  • 20
    • 2542477191 scopus 로고    scopus 로고
    • Development of high affinity camptothecin-bombesin conjugates that have targeted cytotoxicity for bombesin receptor-containing tumor cells
    • Moody TW, Mantey SA, Pradhan TK, Schumann M, Nakagawa T, Martinez A, Fuselier J, Coy DH, Jensen RT (2004) Development of high affinity camptothecin-bombesin conjugates that have targeted cytotoxicity for bombesin receptor-containing tumor cells. J Biol Chem 279:23580-23589
    • (2004) J Biol Chem , vol.279 , pp. 23580-23589
    • Moody, T.W.1    Mantey, S.A.2    Pradhan, T.K.3    Schumann, M.4    Nakagawa, T.5    Martinez, A.6    Fuselier, J.7    Coy, D.H.8    Jensen, R.T.9
  • 21
    • 0344442675 scopus 로고    scopus 로고
    • Somatostatin receptor subtypes in human pheochromocytoma: Subcellular expression pattern and functional relevance for octreotide scintigraphy
    • Mundschenk J, Unger N, Schulz S, Hollt V, Steinke R, Lehnert H (2003) Somatostatin receptor subtypes in human pheochromocytoma: subcellular expression pattern and functional relevance for octreotide scintigraphy. J Clin Endocrinol Metab 88:5150-5157
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5150-5157
    • Mundschenk, J.1    Unger, N.2    Schulz, S.3    Hollt, V.4    Steinke, R.5    Lehnert, H.6
  • 22
    • 0029018519 scopus 로고
    • Cloning of a receptor for amphibian [Phe13]bombesin distinct from the receptor for gastrin-releasing peptide: Identification of a fourth bombesin receptor subtype (BB4)
    • Nagalla SR, Barry BJ, Creswick KC, Eden P, Taylor JT, Spindel ER (1995) Cloning of a receptor for amphibian [Phe13]bombesin distinct from the receptor for gastrin-releasing peptide: identification of a fourth bombesin receptor subtype (BB4). Proc Natl Acad Sci USA 92:6205-6209
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6205-6209
    • Nagalla, S.R.1    Barry, B.J.2    Creswick, K.C.3    Eden, P.4    Taylor, J.T.5    Spindel, E.R.6
  • 24
    • 21444441255 scopus 로고    scopus 로고
    • Development and function of bombesin-like peptides and their receptors
    • Ohki-Hamazaki H, Iwabuchi M, Maekawa F (2005) Development and function of bombesin-like peptides and their receptors. Int J Dev Biol 49:293-300
    • (2005) Int J Dev Biol , vol.49 , pp. 293-300
    • Ohki-Hamazaki, H.1    Iwabuchi, M.2    Maekawa, F.3
  • 25
    • 0035958027 scopus 로고    scopus 로고
    • Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst (3) receptor function by heterodimerization with sst(2A)
    • Pfeiffer M, Koch T, Schroder H, Klutzny M, Kirscht S, Kreienkamp HJ, Hollt V, Schulz S (2001) Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst (3) receptor function by heterodimerization with sst(2A). J Biol Chem 276:14027-14036
    • (2001) J Biol Chem , vol.276 , pp. 14027-14036
    • Pfeiffer, M.1    Koch, T.2    Schroder, H.3    Klutzny, M.4    Kirscht, S.5    Kreienkamp, H.J.6    Hollt, V.7    Schulz, S.8
  • 26
    • 0033756052 scopus 로고    scopus 로고
    • In vivo inhibition of PC-3 human androgen-independent prostate cancer by a targeted cytotoxic bombesin analogue, AN-215
    • Plonowski A, Nagy A, Schally AV, Sun B, Groot K, Halmos G (2000) In vivo inhibition of PC-3 human androgen-independent prostate cancer by a targeted cytotoxic bombesin analogue, AN-215. Int J Cancer 88:652-657
    • (2000) Int J Cancer , vol.88 , pp. 652-657
    • Plonowski, A.1    Nagy, A.2    Schally, A.V.3    Sun, B.4    Groot, K.5    Halmos, G.6
  • 27
    • 0037907532 scopus 로고    scopus 로고
    • Concomitant expression of several peptide receptors in neuroendocrine tumours: Molecular basis for in vivo multireceptor tumour targeting
    • Reubi JC, Waser B (2003) Concomitant expression of several peptide receptors in neuroendocrine tumours: molecular basis for in vivo multireceptor tumour targeting. Eur J Nucl Med Mol Imaging 30:781-793
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 781-793
    • Reubi, J.C.1    Waser, B.2
  • 28
    • 0036554956 scopus 로고    scopus 로고
    • Bombesin receptor subtypes in human cancers: Detection with the universal radioligand (125)I-[D-TYR(6), beta-ALA(11), PHE(13), NLE(14)] bombesin(6-14)
    • Reubi JC, Wenger S, Schmuckli-Maurer J, Schaer JC, Gugger M (2002) Bombesin receptor subtypes in human cancers: detection with the universal radioligand (125)I-[D-TYR(6), beta-ALA(11), PHE(13), NLE(14)] bombesin(6-14). Clin Cancer Res 8:1139-1146
    • (2002) Clin Cancer Res , vol.8 , pp. 1139-1146
    • Reubi, J.C.1    Wenger, S.2    Schmuckli-Maurer, J.3    Schaer, J.C.4    Gugger, M.5
  • 30
    • 14844354089 scopus 로고    scopus 로고
    • Candidates for peptide receptor radiotherapy today and in the future
    • Reubi JC, Macke HR, Krenning EP (2005) Candidates for peptide receptor radiotherapy today and in the future. J Nucl Med 46 (Suppl 1):67S-75S
    • (2005) J Nucl Med , vol.46 , Issue.1 SUPPL.
    • Reubi, J.C.1    Macke, H.R.2    Krenning, E.P.3
  • 32
    • 0034125452 scopus 로고    scopus 로고
    • Immunohistochemical determination of five somatostatin receptors in meningioma reveals frequent overexpression of somatostatin receptor subtype sst2A
    • Schulz S, Pauli SU, Handel M, Dietzmann K, Firsching R, Hollt V (2000) Immunohistochemical determination of five somatostatin receptors in meningioma reveals frequent overexpression of somatostatin receptor subtype sst2A. Clin Cancer Res 6:1865-1874
    • (2000) Clin Cancer Res , vol.6 , pp. 1865-1874
    • Schulz, S.1    Pauli, S.U.2    Handel, M.3    Dietzmann, K.4    Firsching, R.5    Hollt, V.6
  • 33
    • 11144230455 scopus 로고    scopus 로고
    • Immunocytochemical identification of VPAC1, VPAC2, and PAC1 receptors in normal and neoplastic human tissues with subtype-specific antibodies
    • Schulz S, Rocken C, Mawrin C, Weise W, Hollt V (2004) Immunocytochemical identification of VPAC1, VPAC2, and PAC1 receptors in normal and neoplastic human tissues with subtype-specific antibodies. Clin Cancer Res 10:8235-8242
    • (2004) Clin Cancer Res , vol.10 , pp. 8235-8242
    • Schulz, S.1    Rocken, C.2    Mawrin, C.3    Weise, W.4    Hollt, V.5
  • 34
    • 27744468305 scopus 로고    scopus 로고
    • Immunohistochemical localization of CCK1 cholecystokinin receptors in normal and neoplastic human tissues
    • Schulz S, Rocken C, Mawrin C (2005) Immunohistochemical localization of CCK1 cholecystokinin receptors in normal and neoplastic human tissues. J Clin Endocrinol Metab 90:6149-6155
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 6149-6155
    • Schulz, S.1    Rocken, C.2    Mawrin, C.3
  • 36
    • 0347991822 scopus 로고    scopus 로고
    • Gastrin releasing peptide (GRP) receptor targeted radiopharmaceuticals: A concise update
    • Smith CJ, Volkert WA, Hoffman TJ (2003) Gastrin releasing peptide (GRP) receptor targeted radiopharmaceuticals: a concise update. Nucl Med Biol 30:861-868
    • (2003) Nucl Med Biol , vol.30 , pp. 861-868
    • Smith, C.J.1    Volkert, W.A.2    Hoffman, T.J.3
  • 37
    • 27144533633 scopus 로고    scopus 로고
    • Radiolabeled peptide conjugates for targeting of the bombesin receptor superfamily subtypes
    • Smith CJ, Volkert WA, Hoffman TJ (2005) Radiolabeled peptide conjugates for targeting of the bombesin receptor superfamily subtypes. Nucl Med Biol 32:733-740
    • (2005) Nucl Med Biol , vol.32 , pp. 733-740
    • Smith, C.J.1    Volkert, W.A.2    Hoffman, T.J.3
  • 38
    • 27744575622 scopus 로고    scopus 로고
    • Inhibition of human androgen-independent PC-3 and DU-145 prostate cancers by antagonists of bombesin and growth hormone releasing hormone is linked to PKC, MAPK and c-Jun intracellular signalling
    • Stangelberger A, Schally AV, Varga JL, Zarandi M, Cai RZ, Baker B, Hammann BD, Armatis P, Kanashiro CA (2005) Inhibition of human androgen-independent PC-3 and DU-145 prostate cancers by antagonists of bombesin and growth hormone releasing hormone is linked to PKC, MAPK and c-Jun intracellular signalling. Eur J Cancer 41:2735-2744
    • (2005) Eur J Cancer , vol.41 , pp. 2735-2744
    • Stangelberger, A.1    Schally, A.V.2    Varga, J.L.3    Zarandi, M.4    Cai, R.Z.5    Baker, B.6    Hammann, B.D.7    Armatis, P.8    Kanashiro, C.A.9
  • 39
    • 0033953894 scopus 로고    scopus 로고
    • Presence of receptors for bombesin/gastrin-releasing peptide and mRNA for three receptor subtypes in human prostate cancers
    • Sun B, Halmos G, Schally AV, Wang X, Martinez M (2000) Presence of receptors for bombesin/gastrin-releasing peptide and mRNA for three receptor subtypes in human prostate cancers. Prostate 42:295-303
    • (2000) Prostate , vol.42 , pp. 295-303
    • Sun, B.1    Halmos, G.2    Schally, A.V.3    Wang, X.4    Martinez, M.5
  • 40
    • 0034733778 scopus 로고    scopus 로고
    • The presence of receptors for bombesin/GRP and mRNA for three receptor subtypes in human ovarian epithelial cancers
    • Sun B, Schally AV, Halmos G (2000) The presence of receptors for bombesin/GRP and mRNA for three receptor subtypes in human ovarian epithelial cancers. Regul Pept 90:77-84
    • (2000) Regul Pept , vol.90 , pp. 77-84
    • Sun, B.1    Schally, A.V.2    Halmos, G.3
  • 42
    • 4644360336 scopus 로고    scopus 로고
    • Synthesis and evaluation of bombesin derivatives on the basis of pan-bombesin peptides labeled with indium-111, lutetium-177, and yttrium-90 for targeting bombesin receptor-expressing tumors
    • Zhang H, Chen J, Waldherr C, Hinni K, Waser B, Reubi JC, Maecke HR (2004) Synthesis and evaluation of bombesin derivatives on the basis of pan-bombesin peptides labeled with indium-111, lutetium-177, and yttrium-90 for targeting bombesin receptor-expressing tumors. Cancer Res 64:6707-6715
    • (2004) Cancer Res , vol.64 , pp. 6707-6715
    • Zhang, H.1    Chen, J.2    Waldherr, C.3    Hinni, K.4    Waser, B.5    Reubi, J.C.6    Maecke, H.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.