메뉴 건너뛰기




Volumn 2005, Issue , 2005, Pages 262-274

Systems biology: Melting the boundaries in drug discovery research

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL METHODS; INDUSTRIAL RESEARCH; INFORMATION MANAGEMENT; MOLECULAR BIOLOGY; PHARMACODYNAMICS; PROJECT MANAGEMENT;

EID: 33748860464     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/PICMET.2005.1509700     Document Type: Conference Paper
Times cited : (3)

References (56)
  • 1
    • 0032818129 scopus 로고    scopus 로고
    • New institute to study systems biology
    • Agarwal, A.; "New institute to study systems biology," Nature Biotechnology, vol. 17, pp. 743-744, 1999.
    • (1999) Nature Biotechnology , vol.17 , pp. 743-744
    • Agarwal, A.1
  • 2
    • 33748854518 scopus 로고    scopus 로고
    • A new biological paradigm: Innovation and intellectual property in systems biology
    • submitted
    • Allarakhia, M.; "A new biological paradigm: Innovation and intellectual property in systems biology," Nature Biotechnology, submitted.
    • Nature Biotechnology
    • Allarakhia, M.1
  • 3
    • 84934453759 scopus 로고
    • Complementary and external linkages: The strategies of large firms in biotechnology
    • Arora, A. and A. Gambardella; "Complementary and external linkages: The strategies of large firms in biotechnology," Journal of Industrial Economics, vol. 38, pp. 361-379, 1990.
    • (1990) Journal of Industrial Economics , vol.38 , pp. 361-379
    • Arora, A.1    Gambardella, A.2
  • 6
    • 0026484410 scopus 로고
    • Academic-industry relationships in the life sciences: Extent, consequences, and management
    • Blumenthal, D.; "Academic-industry relationships in the life sciences: Extent, consequences, and management," Journal of the American Medical Association, vol. 268. pp. 3344-3349, 1992.
    • (1992) Journal of the American Medical Association , vol.268 , pp. 3344-3349
    • Blumenthal, D.1
  • 10
    • 0002103691 scopus 로고    scopus 로고
    • A resource-based theory of strategic alliances
    • Das, T.K. and B. S. Teng; "A resource-based theory of strategic alliances," Journal of Management, vol. 26, pp. 31-61, 2000.
    • (2000) Journal of Management , vol.26 , pp. 31-61
    • Das, T.K.1    Teng, B.S.2
  • 11
    • 25144469744 scopus 로고    scopus 로고
    • Cell signaling alliance gets under way
    • Devine, K.; "Cell signaling alliance gets under way," The Scientist, vol. 14, 2000.
    • (2000) The Scientist , vol.14
    • Devine, K.1
  • 12
    • 0034303634 scopus 로고    scopus 로고
    • Genomics in the public domain: Strategy and policy
    • Eisenberg, R. S.; "Genomics in the public domain: Strategy and policy," Nature Reviews Genetics, vol. 1, pp. 70-74, 2000.
    • (2000) Nature Reviews Genetics , vol.1 , pp. 70-74
    • Eisenberg, R.S.1
  • 15
    • 0141561891 scopus 로고    scopus 로고
    • Integrating 'omic' information: A bridge between genomics and systems biology
    • Ge, H., A. J. M. Walhout and M. Vidal; "Integrating 'omic' information: a bridge between genomics and systems biology," Trends in Genetics, vol. 19, pp. 551-560, 2003.
    • (2003) Trends in Genetics , vol.19 , pp. 551-560
    • Ge, H.1    Walhout, A.J.M.2    Vidal, M.3
  • 16
    • 0034673417 scopus 로고    scopus 로고
    • Pushing the frontiers of interdisciplinary research: An idea whose time has come
    • Gershon, D.; "Pushing the frontiers of interdisciplinary research: an idea whose time has come," Nature, vol. 404, pp. 313-315, 2000.
    • (2000) Nature , vol.404 , pp. 313-315
    • Gershon, D.1
  • 17
    • 55549093180 scopus 로고
    • External partnering as a response to innovation barriers and global competition in biotechnology
    • Greis, N. P., M. D. Dibner and A. S. Bean; "External partnering as a response to innovation barriers and global competition in biotechnology," Research Policy, vol. 24, pp. 609-630, 1995.
    • (1995) Research Policy , vol.24 , pp. 609-630
    • Greis, N.P.1    Dibner, M.D.2    Bean, A.S.3
  • 18
    • 0002666695 scopus 로고
    • Unilateral commitments and the importance of process in alliances
    • Gulati, R., T. Khanna and N., Nohria; "Unilateral commitments and the importance of process in alliances," Sloan Management Review, vol. 35, pp. 61-69, 1994.
    • (1994) Sloan Management Review , vol.35 , pp. 61-69
    • Gulati, R.1    Khanna, T.2    Nohria, N.3
  • 19
    • 33748869412 scopus 로고    scopus 로고
    • Toward an integrated knowledge management cycle in cumulative open innovation networks
    • Paper presented Sesimbra, Portugal: RADMA, July 7-9
    • Hacklin, F., K. Lopperi, J.-P. Bergman and C. Marxt; "Toward an integrated knowledge management cycle in cumulative open innovation networks," Paper presented at Proceedings of The R&D Management Conference, Sesimbra, Portugal: RADMA, July 7-9 2004.
    • (2004) Proceedings of the R&D Management Conference
    • Hacklin, F.1    Lopperi, K.2    Bergman, J.-P.3    Marxt, C.4
  • 20
    • 84989085762 scopus 로고
    • The strategic analysis of intangible resources
    • Hall, R.; "The strategic analysis of intangible resources," Strategic Management Journal, vol. 13, pp. 135-144, 1992.
    • (1992) Strategic Management Journal , vol.13 , pp. 135-144
    • Hall, R.1
  • 21
    • 33748489582 scopus 로고    scopus 로고
    • Access to data and intellectual property: Scientific exchange in genome research
    • Washington, DC: National Academy Press
    • Hilgartner, S.; "Access to data and intellectual property: Scientific exchange in genome research," in Intellectual Property Rights and Research Tools in Molecular Biology, Washington, DC: National Academy Press, 1996.
    • (1996) Intellectual Property Rights and Research Tools in Molecular Biology
    • Hilgartner, S.1
  • 22
    • 33748859338 scopus 로고    scopus 로고
    • The university office of technology transfer: The inventor/researcher's view
    • University of Washington, Seattle, WA: CASPRIP
    • Hood, L. E.; "The university office of technology transfer: The inventor/researcher's view," CASRIP Symposium Publication Series No.5, University of Washington, Seattle, WA: CASPRIP, 2000.
    • (2000) CASRIP Symposium Publication Series No.5
    • Hood, L.E.1
  • 23
    • 0037342537 scopus 로고    scopus 로고
    • The systems biology markup language (SBML): A medium for representation and exchange of biochemical network models
    • Hucka, M. et al.; "The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models", Bioinformatics, vol. 19, pp. 524-531, 2003.
    • (2003) Bioinformatics , vol.19 , pp. 524-531
    • Hucka, M.1
  • 25
    • 0035860545 scopus 로고    scopus 로고
    • Pathway databases: A case study in computational symbolic theories
    • Karp, P. D.; "Pathway databases: A case study in computational symbolic theories," Science, vol. 293, pp. 2040-2044, 2001.
    • (2001) Science , vol.293 , pp. 2040-2044
    • Karp, P.D.1
  • 26
    • 0003065454 scopus 로고    scopus 로고
    • Systems biology: Toward systems-level understanding of biological systems
    • H. Kitano, Ed. Cambridge, MA: MIT Press
    • Kitano, H.; "Systems biology: Toward systems-level understanding of biological systems," in Foundation of Systems Biology, H. Kitano, Ed. Cambridge, MA: MIT Press, 2001.
    • (2001) Foundation of Systems Biology
    • Kitano, H.1
  • 27
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: A brief overview
    • Kitano, H.; "Systems biology: A brief overview," Science, vol. 295, pp. 1662-1664, 2002.
    • (2002) Science , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 28
    • 0037079054 scopus 로고    scopus 로고
    • Computational systems biology
    • Kitano, H.; "Computational systems biology," Nature, vol. 420, pp. 206-210, 2002.
    • (2002) Nature , vol.420 , pp. 206-210
    • Kitano, H.1
  • 29
    • 84989051609 scopus 로고    scopus 로고
    • Joint ventures: Theoretical and empirical perspectives
    • Kogut, B.; "Joint ventures: Theoretical and empirical perspectives," Strategic Management Journal, vol. 9, pp. 319-332, 1998.
    • (1998) Strategic Management Journal , vol.9 , pp. 319-332
    • Kogut, B.1
  • 30
    • 1542710569 scopus 로고    scopus 로고
    • Social dilemmas: The anatomy of cooperation
    • Kollock, P.; "Social dilemmas: The anatomy of cooperation," Annual Review of Sociology, vol. 24, pp. 183-214, 1998.
    • (1998) Annual Review of Sociology , vol.24 , pp. 183-214
    • Kollock, P.1
  • 31
    • 0032372839 scopus 로고    scopus 로고
    • The interorganizational learning dilemma: Collective knowledge development in strategic alliances
    • Larsson, R., L. Bengtsson, K. Henriksson and J. Sparks; "The interorganizational learning dilemma: Collective knowledge development in strategic alliances," Organizational Science, vol. 9, pp. 285-305, 1998.
    • (1998) Organizational Science , vol.9 , pp. 285-305
    • Larsson, R.1    Bengtsson, L.2    Henriksson, K.3    Sparks, J.4
  • 32
    • 0030523972 scopus 로고    scopus 로고
    • Social networks, learning and flexibility: Sourcing scientific knowledge in new biotechnology firms
    • Liebeskind, J. P., A. L. Oliver, L. Zucker and M. Brewer; "Social networks, learning and flexibility: Sourcing scientific knowledge in new biotechnology firms," Organization science, vol. 7, pp. 428-443, 1996.
    • (1996) Organization Science , vol.7 , pp. 428-443
    • Liebeskind, J.P.1    Oliver, A.L.2    Zucker, L.3    Brewer, M.4
  • 33
    • 0036606173 scopus 로고    scopus 로고
    • Text-based knowledge discovery: Search and mining of life-science documents
    • Mack, R. and M. Hehenberger; "Text-based knowledge discovery: Search and mining of life-science documents," Drug Discovery Today, vol. 7, pp. S89-S-98, 2002.
    • (2002) Drug Discovery Today , vol.7
    • Mack, R.1    Hehenberger, M.2
  • 34
    • 0006146505 scopus 로고
    • Intellectual property rights and bargaining breakdown: The case of blocking patents
    • Merges, R.; "Intellectual property rights and bargaining breakdown: The case of blocking patents," Tennessee Law Review, vol. 62, pp. 75-106, 1994.
    • (1994) Tennessee Law Review , vol.62 , pp. 75-106
    • Merges, R.1
  • 35
    • 0041361369 scopus 로고    scopus 로고
    • Property rights theory and the commons: The case of scientific research
    • New York, NY: Cambridge University Press
    • Merges, R.; "Property rights theory and the commons: The case of scientific research," in Scientific Innovation, Philosophy and Public Policy, New York, NY: Cambridge University Press, 1996.
    • (1996) Scientific Innovation, Philosophy and Public Policy
    • Merges, R.1
  • 36
    • 35248840928 scopus 로고
    • Priorities in scientific discovery: A chapter in the sociology of science
    • Merton, R.; "Priorities in scientific discovery: A chapter in the sociology of science," American Sociological Review, vol. 22, pp. 635-659, 1957.
    • (1957) American Sociological Review , vol.22 , pp. 635-659
    • Merton, R.1
  • 37
    • 33748856107 scopus 로고    scopus 로고
    • Take two for Stanford's Bio-X project
    • 06/15/03
    • Moad, J.; "Take two for Stanford's Bio-X project," Bio-IT Bulletin, 06/15/03.
    • Bio-IT Bulletin
    • Moad, J.1
  • 38
    • 0037107880 scopus 로고    scopus 로고
    • Knowledge assembly for the life sciences
    • Neumann, E. and J. Thomas; "Knowledge assembly for the life sciences," Drug Discovery Today, vol. 7, pp. S160-S162, 2002.
    • (2002) Drug Discovery Today , vol.7
    • Neumann, E.1    Thomas, J.2
  • 39
    • 0036092301 scopus 로고    scopus 로고
    • The informatics for making sense of the genome: A progress report from the Biopathways Consortium
    • Neumann, E. K. and V. Schachter; "The informatics for making sense of the genome: A progress report from the Biopathways Consortium," Comparative and Functional Genomics, vol. 3, pp. 115-118, 2002.
    • (2002) Comparative and Functional Genomics , vol.3 , pp. 115-118
    • Neumann, E.K.1    Schachter, V.2
  • 41
    • 0000820455 scopus 로고
    • Neither market nor hierarchy: Network forms of organization
    • B. M. Staw and L.L. Cummings, Eds. Greenwich, CT: JAI Press
    • Powell, W.W.; "Neither market nor hierarchy: Network forms of organization," in Research in Organizational Behavior, B. M. Staw and L.L. Cummings, Eds. Greenwich, CT: JAI Press, 1990.
    • (1990) Research in Organizational Behavior
    • Powell, W.W.1
  • 42
    • 0030306449 scopus 로고    scopus 로고
    • Inter-organizational collaboration and the locus of innovation: Network of learning in biotechnology
    • Powell, W. W., K. K. Koput and L. Smith-Doerr; "Inter-organizational collaboration and the locus of innovation: Network of learning in biotechnology," Administrative Science Quarterly, vol. 41, pp. 116-145, 1996.
    • (1996) Administrative Science Quarterly , vol.41 , pp. 116-145
    • Powell, W.W.1    Koput, K.K.2    Smith-Doerr, L.3
  • 44
    • 0034665717 scopus 로고    scopus 로고
    • Publication rights in the era of open data release policies
    • Rowen, L., G. K. S. Wong, R. P. Lane and L. Hood; "Publication rights in the era of open data release policies," Science, vol. 289, pp. 1881+, 2000.
    • (2000) Science , vol.289 , pp. 1881
    • Rowen, L.1    Wong, G.K.S.2    Lane, R.P.3    Hood, L.4
  • 45
    • 0034064689 scopus 로고    scopus 로고
    • A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks
    • Schuster, S., D.A. Fell and T. Dandekar; "A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks," Nature Biotechnology, vol. 18, pp. 326-332, 2000.
    • (2000) Nature Biotechnology , vol.18 , pp. 326-332
    • Schuster, S.1    Fell, D.A.2    Dandekar, T.3
  • 46
    • 0002730808 scopus 로고
    • Standing on the shoulders of giants: Cumulative research and the patent law
    • Scotchmer, S.; "Standing on the shoulders of giants: Cumulative research and the patent law," The Journal of Economic Perspectives, vol. 5, pp. 29-41, 1991.
    • (1991) The Journal of Economic Perspectives , vol.5 , pp. 29-41
    • Scotchmer, S.1
  • 47
    • 0030954632 scopus 로고    scopus 로고
    • Organizational learning in cooperative alliances: Some case studies in biotechnology
    • Senker, J. and M. Sharp; "Organizational learning in cooperative alliances: Some case studies in biotechnology," Technology Analysis & Strategic Management, vol. 9, pp. 35-51, 1997.
    • (1997) Technology Analysis & Strategic Management , vol.9 , pp. 35-51
    • Senker, J.1    Sharp, M.2
  • 48
    • 20244376293 scopus 로고    scopus 로고
    • Exploring the systems of life
    • Service, R. F.; "Exploring the systems of life," Science, vol. 284, pp. 80-83, 1999.
    • (1999) Science , vol.284 , pp. 80-83
    • Service, R.F.1
  • 49
    • 0031599435 scopus 로고    scopus 로고
    • Cooperation in R&D in the pharmaceutical industry-The network as an organizational innovation governing technological innovation
    • Starpoli, C.; "Cooperation in R&D in the pharmaceutical industry-The network as an organizational innovation governing technological innovation," Technovation, vol. 18, pp. 13-23, 1998.
    • (1998) Technovation , vol.18 , pp. 13-23
    • Starpoli, C.1
  • 50
    • 36148958185 scopus 로고    scopus 로고
    • MIT's computational and systems biology initiative
    • Boston, MA: DDT®
    • Tadmor, B.; "MIT's Computational and Systems Biology Initiative," Presented at the Drug Discovery Technology® Conference, Boston, MA: DDT®, 2004.
    • (2004) Drug Discovery Technology® Conference
    • Tadmor, B.1
  • 51
    • 0037590604 scopus 로고    scopus 로고
    • Overview of the alliance for cellular signaling
    • Taussig, R., R. Ranganathan, E. M. Ross and A. G. Gilman; "Overview of the Alliance for Cellular Signaling," Nature, vol. 420, pp. 703-706, 2002.
    • (2002) Nature , vol.420 , pp. 703-706
    • Taussig, R.1    Ranganathan, R.2    Ross, E.M.3    Gilman, A.G.4
  • 52
    • 38549086633 scopus 로고
    • Profiting for technological innovation: Implications for integration, collaboration, licensing and public policy
    • Teece, D. J.; "Profiting for technological innovation: Implications for integration, collaboration, licensing and public policy," Research Policy, vol. 15, pp. 785-805, 1986.
    • (1986) Research Policy , vol.15 , pp. 785-805
    • Teece, D.J.1
  • 53
    • 33748869605 scopus 로고    scopus 로고
    • URL: biox.staiiford.edu, accessed 01/05/2005
    • URL: biox.staiiford.edu, accessed 01/05/2005.
  • 54
    • 33748846498 scopus 로고    scopus 로고
    • URL: csbi.mit.edu, accessed 01/05/2005
    • URL: csbi.mit.edu, accessed 01/05/2005.
  • 55
    • 33748866048 scopus 로고    scopus 로고
    • accessed 01/05/2005
    • URL: www.systemsbiology.org, accessed 01/05/2005.
  • 56
    • 0002090480 scopus 로고    scopus 로고
    • Managing codified knowledge
    • Zack, M. H.; "Managing codified knowledge," Sloan Management Review, vol. 40, 45-58, 1999.
    • (1999) Sloan Management Review , vol.40 , pp. 45-58
    • Zack, M.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.