The early transcriptional response of pig small intestinal mucosa to invasion by Salmonella enterica serovar typhimurium DT104

Molecular Immunology

Volumn 44, Issue 6, 2007, Pages 1316-1322

  Niewold, Theo A ^a,c   Veldhuizen, Edwin J A ^b   van der Meulen, Jan ^a   Haagsman, Henk P ^b   de Wit, Agnes A C ^a   Smits, Mari A ^a   Tersteeg, Monique H G ^b   Hulst, Marcel M ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c Faculty of Bioscience Engineering   (Belgium)

Author keywords

Intestinal immunity; Microarray; Salmonella typhimurium; Small intestine; Transcriptomics

Indexed keywords

INTERLEUKIN 8; STAT3 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; DNA MICROARRAY; GASTROENTERITIS; GENE EXPRESSION; INFLAMMATION; JEJUNUM; NONHUMAN; PRIORITY JOURNAL; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM; SMALL INTESTINE MUCOSA; SWINE;

ANIMALS; INTESTINAL MUCOSA; INTESTINE, SMALL; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; SWINE; TRANSCRIPTION, GENETIC;

SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SALMONELLA TYPHIMURIUM; SUS SCROFA;

EID: 33748767133     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.05.013     Document Type: Article

References (29)

1. Darwin K.H., and Miller V.L. Molecular basis of the interaction of Salmonella with the intestinal mucosa. Clin. Microbiol. Rev. 12 (1999) 405-428
2. de Jonge W.J., van der Zanden E.P., The F.O., Bijlsma M.F., van Westerloo D.J., Bennink R.J., Berthoud H.R., Uematsu S., Akira S., van den Wijngaarden R.M., and Boeckxstaens G.E. Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway. Nat. Immunol. 6 (2005) 844-851
3. Detweiler C.S., Cunanan D.B., and Falkow S. Host microarray analysis reveals a role for the Salmonella response regulator phoP in human macrophage cell death. Proc. Natl. Acad. Sci. USA 98 (2001) 5850-5855
4. Dvorak C.M.T., Hyland K.A., Machado J.G., Zhang Y., Fahrenkrug S.C., and Murtaugh M.P. Gene discovery and expression profiling in porcine Peyer's patch. Vet. Immunol. Immunopathol. 105 (2005) 301-315
5. Eckmann L., Smith J.R., Housley M.P., Dwinell M.B., and Kagnoff M.F. Analysis by high density cDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with the invasive enteric bacteria Salmonella. J. Biol. Chem. 275 (2000) 14084-14094
6. Finlay B.B., and Brumell J.H. Salmonella interactions with host cells: in vitro to in vivo. Phil. Trans. R. Soc. Lond. B 355 (2000) 623-631
7. Gianella R., Gots R.E., Charney A.N., Greenough III W.B., and Formal S.B. Pathogenesis of Salmonella-mediated intestinal fluid secretion: activation of adenylate cyclase and inhibition by indomethacin. Gastroenterology 69 (1975) 1238-1245
8. Haque A., Bowe F., Fitzhenry R.J., Frankel G., Thomson M., Murch S., Stevens M.P., Wallis T.S., Philips A.D., and Dougan G. Early interactions of Salmonella enterica serovar typhimurium with human small intestinal epithelial explants. Gut 53 (2004) 1424-1430
9. Hendriksen S.W.M., Orsel K., Wagenaar J.A., Miko A., and van Duijkeren E. Animal-to-human transmission of Salmonella typhimurium DT104A variant. Emerg. Infect. Dis. 10 (2004) 2225-2227
10. Hobbie S., Chen L.M., Davis R.J., and Galan J.E. Involvement of mitogen-activated protein kinase pathways in the nuclear responses and cytokine production induced by Salmonella typhimurium in cultured intestinal epithelial cells. J. Immunol. 159 (1997) V5550-V5559
11. Iovanna J., Orelle B., Keim V., and Dagorn J.C. Messenger-RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis. J. Biol. Chem. 266 (1991) 24664-24669
12. Kubo M., Hanada T., and Yoshimura A. Suppressors of cytokine signalling and immunity. Nat. Immunol. 4 (2003) 1169-1174
13. Metz C.N., and Tracey K.J. It takes nerve to dampen inflammation. Nat. Immunol. 6: (2005) 756-757
14. Meyerholz D.K., Stabel T.J., Ackermann M.R., Carlson S.A., Jones B.D., and Pohlenz J. Early epithelial invasion by Salmonella enterica serovar typhimurium DT104 in the swine ileum. Vet. Pathol. 39 (2002) 712-720
15. Moucadel V., Soubeyran P., Vasseur S., Dusetti N.J., Dagorn J.C., and Iovanna J.L. Cdx1 promotes cellular growth of epithelial cells through induction of the secretory protein PAP I. Eur. J. Cell Biol. 80 (2001) 156-163
16. Mudter J., Weigmann B., Bartsch B., Kiesslich R., Strand D., Galle P.R., Lehr H.A., Schmidt J., and Neurath M.F. Activation pattern of signal transducers and activators of transcription (STAT) factors in inflammatory bowel diseases. Am. J. Gastrenterol. 100 (2005) 64-72
17. Nau G.J., Richmond J.F., Schlesinger A., Jennings E.G., Lander E.S., and Young R.A. Human macrophage activation programs induced by bacterial pathogens. Proc. Natl. Acad. Sci. USA 99 (2002) 1503-1508
18. Niewold T.A., Kerstens H.H.D., van der Meulen J., Smits M.A., and Hulst M.M. Development of a porcine small intestinal cDNA microarray: characterization, and functional analysis of the response to enterotoxic E. coli. Vet. Immunol. Immunopathol. 105 (2005) 317-329
19. Smith P.D., Ochsenbauer-Jambor C., and Smythies L.E. Intestinal macrophages: unique effectors of the innate immune response. Immunol. Rev. 206 (2005) 149-159
20. Reid G., Sanders M.E., Gaskins H.R., Gibson G.R., Mercenier A., Rastall R., Roberfroid M., Rowland I., Cherbut C., and Klaenhammer T.R. New scientific paradigms for probiotics and prebiotics. J. Clin. Gastroenterol. 7 (2003) 105-118
21. Rosenberger C.M., Scott M.G., Gold M.R., Hancock R.E.W., and Finlay B.B. Salmonella typhimurium infection and lipopolysaccharide stimulation induce similar changes in macrophage gene expression. J. Immunol. 164 (2000) 5894-5904
22. Rosenberger C.M., Pollard A.J., and Finlay B.B. Gene array technology to determine host responses to Salmonella. Microbes Infect. 3 (2001) 1353-1360
23. Salmela M.T., MacDonald T.T., Black D., Irvine B., Zhuma T., Saarialho-Kere U., and Pender S.L. Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation. Gut 51 (2002) 540-547
24. Staerkel P., Sempoux C., Van Den Berge V., Stevens M., De Saeger C., Desager J.P., and Horsmans Y. Cyp 3A proteins are expressed in human neutrophils and lymphocytes but are not induced by rifampicin. Life Sci. 64 (1999) 643-653
25. Tersteeg M.H.G., Koolmees P.A., and van Knapen F. Immunohistochemical detection of brain tissue in heated meat products. Meat Sci. 61 (2002) 67-72
26. Tracey K.J. The inflammatory reflex. Nature 420 (2002) 853-859
27. Vasseur S., Folch-Puy E., Hlouschek V., Garcia S., Fiedler F., Lerch M.M., Dagorn J.C., Closa D., and Iovanna J.L. p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I. J. Biol. Chem. 279 (2004) 7199-7207
28. Veldhuizen E.J.A., van Dijk A., Tersteeg M.H.G., Kalkhofe S., van der Meulen J., Niewold T.A., and Haagsman H.P. Expression of β-defensins pBD-1 and pBD2 along the small intestinal tract of the pig; lack of upregulation in vivo upon Salmonella typhimurium infection. Mol. Immunol. 44 (2007) 276-283
29. Wernersson R., Schierup M.H., Jorgensen F.G., Gorodkin J., Panitz F., Staerfeldt H.H., Christensen O.F., Mailund T., Hornshoj H., Klein A., Wang J., Liu B., Hu S., Dong W., Li W., Wong G.K., Yu J., Wang J., Bendixen C., Fredholm M., Brunak S., Yang H., and Bolund L. Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing. BMC Genom. 6 (2005) 70