-
1
-
-
0026791936
-
Post-translational chemical modification(s) of proteins
-
Han KK & Martinage A (1992) Post-translational chemical modification(s) of proteins. Int J Biochem 24, 19-28.
-
(1992)
Int J Biochem
, vol.24
, pp. 19-28
-
-
Han, K.K.1
Martinage, A.2
-
2
-
-
0030725756
-
Furin: A mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins
-
Nakayama K (1997) Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins. Biochem J 327, 625-635.
-
(1997)
Biochem J
, vol.327
, pp. 625-635
-
-
Nakayama, K.1
-
4
-
-
13844257478
-
The yeast CLC chloride channel is proteolytically processed by the furin-like protease Kex2p in the first extracellular loop
-
Wachter A & Schwappach B (2005) The yeast CLC chloride channel is proteolytically processed by the furin-like protease Kex2p in the first extracellular loop. FEBS Lett 579, 1149-1153.
-
(2005)
FEBS Lett
, vol.579
, pp. 1149-1153
-
-
Wachter, A.1
Schwappach, B.2
-
5
-
-
2442427527
-
Epithelial sodium channels are activated by furin-dependent proteolysis
-
Hughey RP, Bruns JB, Kinlough CL, Harkleroad KL, Tong Q, Carattino MD, Johnson JP, Stockand JD & Kleyman TR (2004) Epithelial sodium channels are activated by furin-dependent proteolysis. J Biol Chem 279, 18111-18114.
-
(2004)
J Biol Chem
, vol.279
, pp. 18111-18114
-
-
Hughey, R.P.1
Bruns, J.B.2
Kinlough, C.L.3
Harkleroad, K.L.4
Tong, Q.5
Carattino, M.D.6
Johnson, J.P.7
Stockand, J.D.8
Kleyman, T.R.9
-
6
-
-
0036791359
-
Furin at the cutting edge: From protein traffic to embryogenesis and disease
-
Thomas G (2002) Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol 3, 753-766.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 753-766
-
-
Thomas, G.1
-
7
-
-
0032560449
-
alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: Application as an antipathogenic agent
-
Jean F, Stella K, Thomas L, Liu G, Xiang Y, Reason AJ & Thomas G (1998) alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent. Proc Natl Acad Sci 95, 7293-7298.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 7293-7298
-
-
Jean, F.1
Stella, K.2
Thomas, L.3
Liu, G.4
Xiang, Y.5
Reason, A.J.6
Thomas, G.7
-
9
-
-
7544234501
-
Inhibition of furin by serpin Spn4A from Drosophila melanogaster
-
Oley M, Letzel MC & Ragg H (2004) Inhibition of furin by serpin Spn4A from Drosophila melanogaster. FEBS Lett 577, 165-169.
-
(2004)
FEBS Lett
, vol.577
, pp. 165-169
-
-
Oley, M.1
Letzel, M.C.2
Ragg, H.3
-
10
-
-
3042639565
-
Drosophila serpin 4 functions as a neuroserpin-like inhibitor of subtilisin-like proprotein convertases
-
Osterwalder T, Kuhnen A, Leiserson WM, Kim YS & Keshishian H (2004) Drosophila serpin 4 functions as a neuroserpin-like inhibitor of subtilisin-like proprotein convertases. J Neurosci 24, 5482-5491.
-
(2004)
J Neurosci
, vol.24
, pp. 5482-5491
-
-
Osterwalder, T.1
Kuhnen, A.2
Leiserson, W.M.3
Kim, Y.S.4
Keshishian, H.5
-
11
-
-
0042527443
-
Barley serine proteinase inhibitor 2-derived cyclic peptides as potent and selective inhibitors of convertases PC1/3 and furin
-
Villemure M, Fournier A, Gauthier D, Rabah N, Wilkes BC & Lazure C (2003) Barley serine proteinase inhibitor 2-derived cyclic peptides as potent and selective inhibitors of convertases PC1/3 and furin. Biochemistry 42, 9659-9668.
-
(2003)
Biochemistry
, vol.42
, pp. 9659-9668
-
-
Villemure, M.1
Fournier, A.2
Gauthier, D.3
Rabah, N.4
Wilkes, B.C.5
Lazure, C.6
-
12
-
-
0035964398
-
Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells
-
Bassi DE, Lopez De Cicco R, Mahloogi H, Zucker S, Thomas G & Klein-Szanto AJ (2001) Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells. Proc Natl Acad Sci USA 98, 10326-10331.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10326-10331
-
-
Bassi, D.E.1
Lopez De Cicco, R.2
Mahloogi, H.3
Zucker, S.4
Thomas, G.5
Klein-Szanto, A.J.6
-
13
-
-
10344260714
-
Polyarginine inhibits gp160 processing by furin and suppresses productive human immunodeficiency virus type 1 infection
-
Kibler KV, Miyazato A, Yedavalli VS, Dayton AI, Jacobs BL, Dapolito G, Kim SJ & Jeang KT (2004) Polyarginine inhibits gp160 processing by furin and suppresses productive human immunodeficiency virus type 1 infection. J Biol Chem 279, 49055-49063.
-
(2004)
J Biol Chem
, vol.279
, pp. 49055-49063
-
-
Kibler, K.V.1
Miyazato, A.2
Yedavalli, V.S.3
Dayton, A.I.4
Jacobs, B.L.5
Dapolito, G.6
Kim, S.J.7
Jeang, K.T.8
-
14
-
-
0036893450
-
The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin a in vivo
-
Sarac MS, Cameron A & Lindberg I (2002) The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. Infect Immun 70, 7136-7139.
-
(2002)
Infect Immun
, vol.70
, pp. 7136-7139
-
-
Sarac, M.S.1
Cameron, A.2
Lindberg, I.3
-
15
-
-
0037668063
-
Synthetic peptides derived from the prosegments of proprotein convertase 1/3 and furin are potent inhibitors of both enzymes
-
Basak A & Lazure C (2003) Synthetic peptides derived from the prosegments of proprotein convertase 1/3 and furin are potent inhibitors of both enzymes. Biochem J 373, 231-239.
-
(2003)
Biochem J
, vol.373
, pp. 231-239
-
-
Basak, A.1
Lazure, C.2
-
16
-
-
2542606799
-
Identification of furin pro-region determinants involved in folding and activation
-
Bissonnette L, Charest G, Longpre JM, Lavigne P & Leduc R (2004) Identification of furin pro-region determinants involved in folding and activation. Biochem J 379, 757-763.
-
(2004)
Biochem J
, vol.379
, pp. 757-763
-
-
Bissonnette, L.1
Charest, G.2
Longpre, J.M.3
Lavigne, P.4
Leduc, R.5
-
17
-
-
23344442490
-
Inter-alpha-inhibitor proteins are endogenous furin inhibitors and provide protection against experimental anthrax intoxication
-
Opal SM, Artenstein AW, Cristofaro PA, Jhung JW, Palardy JE, Parejo NA & Lim YP (2005) Inter-alpha-inhibitor proteins are endogenous furin inhibitors and provide protection against experimental anthrax intoxication. Infect Immun 73, 5101-5105.
-
(2005)
Infect Immun
, vol.73
, pp. 5101-5105
-
-
Opal, S.M.1
Artenstein, A.W.2
Cristofaro, P.A.3
Jhung, J.W.4
Palardy, J.E.5
Parejo, N.A.6
Lim, Y.P.7
-
18
-
-
0031917385
-
Inhibition of soluble recombinant furin by human proteinase inhibitor 8
-
Dahlen JR, Jean F, Thomas G, Foster DC & Kisiel W (1998) Inhibition of soluble recombinant furin by human proteinase inhibitor 8. J Biol Chem 273, 1851-1854.
-
(1998)
J Biol Chem
, vol.273
, pp. 1851-1854
-
-
Dahlen, J.R.1
Jean, F.2
Thomas, G.3
Foster, D.C.4
Kisiel, W.5
-
19
-
-
0034020735
-
Nonhistone protein purified from porcine kidney acts as a suicide substrate inhibitor on furin-like enzyme
-
Fei H, Li Y, Wang LX, Luo MJ, Ling MH & Chi CW (2000) Nonhistone protein purified from porcine kidney acts as a suicide substrate inhibitor on furin-like enzyme. Acta Pharmacol Sin 21, 265-270.
-
(2000)
Acta Pharmacol Sin
, vol.21
, pp. 265-270
-
-
Fei, H.1
Li, Y.2
Wang, L.X.3
Luo, M.J.4
Ling, M.H.5
Chi, C.W.6
-
20
-
-
0842313260
-
Prediction of proprotein convertase cleavage sites
-
Duckert P, Brunak S & Blom N (2004) Prediction of proprotein convertase cleavage sites. Protein Eng Des Sel 17, 107-112.
-
(2004)
Protein Eng des Sel
, vol.17
, pp. 107-112
-
-
Duckert, P.1
Brunak, S.2
Blom, N.3
-
21
-
-
10744233286
-
Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks
-
Konishi A, Shimizu S, Hirota J, Takao T, Fan Y, Matsuoka Y, Zhang L, Yoneda Y, Fujii Y, Skoultchi AI et al. (2003) Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks. Cell 114, 673-688.
-
(2003)
Cell
, vol.114
, pp. 673-688
-
-
Konishi, A.1
Shimizu, S.2
Hirota, J.3
Takao, T.4
Fan, Y.5
Matsuoka, Y.6
Zhang, L.7
Yoneda, Y.8
Fujii, Y.9
Skoultchi, A.I.10
-
22
-
-
0015437962
-
Measurement of molecular weights by electrophoresis on SDS-acrylamide gel
-
Weber K, Pringle JR & Osborn M (1972) Measurement of molecular weights by electrophoresis on SDS-acrylamide gel. Methods Enzymol 26, 3-27.
-
(1972)
Methods Enzymol
, vol.26
, pp. 3-27
-
-
Weber, K.1
Pringle, J.R.2
Osborn, M.3
-
23
-
-
25444523218
-
DNA-induced secondary structure of the carboxyl-terminal domain of histone H1
-
Roque A, Iloro I, Ponte I, Arrondo JR & Suau P (2005) DNA-induced secondary structure of the carboxyl-terminal domain of histone H1. J Biol Chem 280, 32141-32147.
-
(2005)
J Biol Chem
, vol.280
, pp. 32141-32147
-
-
Roque, A.1
Iloro, I.2
Ponte, I.3
Arrondo, J.R.4
Suau, P.5
-
24
-
-
0016169865
-
Determination of the helix and b form of proteins in aqueous solution by circular dichroism
-
Chen YH, Yang JT & Chau KH (1974) Determination of the helix and b form of proteins in aqueous solution by circular dichroism. Biochemistry 13, 3350-3359.
-
(1974)
Biochemistry
, vol.13
, pp. 3350-3359
-
-
Chen, Y.H.1
Yang, J.T.2
Chau, K.H.3
-
25
-
-
0347985777
-
Two engineered eglin c mutants potently and selectively inhibiting kexin or furin
-
Liu ZX, Fei H & Chi CW (2004) Two engineered eglin c mutants potently and selectively inhibiting kexin or furin. FEBS Lett 556, 116-120.
-
(2004)
FEBS Lett
, vol.556
, pp. 116-120
-
-
Liu, Z.X.1
Fei, H.2
Chi, C.W.3
-
26
-
-
0037478705
-
Optimization of protease-inhibitor interactions by randomizing adventitious contacts
-
Komiyama T, VanderLugt B, Fugere M, Day R, Kaufman RJ & Fuller RS (2003) Optimization of protease-inhibitor interactions by randomizing adventitious contacts. Proc Natl Acad Sci USA 100, 8205-8210.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8205-8210
-
-
Komiyama, T.1
VanderLugt, B.2
Fugere, M.3
Day, R.4
Kaufman, R.J.5
Fuller, R.S.6
-
27
-
-
0034642235
-
Engineered eglin c variants inhibit yeast and human proprotein processing proteases, Kex2 and furin
-
Komiyama T & Fuller RS (2000) Engineered eglin c variants inhibit yeast and human proprotein processing proteases, Kex2 and furin. Biochemistry 39, 15156-15165.
-
(2000)
Biochemistry
, vol.39
, pp. 15156-15165
-
-
Komiyama, T.1
Fuller, R.S.2
-
28
-
-
0027337354
-
Arg15-Lys17-Arg18 turkey ovomucoid third domain inhibits human furin
-
Lu W, Zhang W, Molloy SS, Thomas G, Ryan K, Chiang Y, Anderson S & Laskowski M Jr (1993) Arg15-Lys17-Arg18 turkey ovomucoid third domain inhibits human furin. J Biol Chem 268, 14583-14585.
-
(1993)
J Biol Chem
, vol.268
, pp. 14583-14585
-
-
Lu, W.1
Zhang, W.2
Molloy, S.S.3
Thomas, G.4
Ryan, K.5
Chiang, Y.6
Anderson, S.7
Laskowski Jr., M.8
-
29
-
-
0030805194
-
Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered alpha 2-macroglobulin containing a furin recognition sequence in the bait region
-
Van Rompaey L, Ayoubi T, Van De Ven W & Marynen P (1997) Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered alpha 2-macroglobulin containing a furin recognition sequence in the bait region. Biochem J 326, 507-514.
-
(1997)
Biochem J
, vol.326
, pp. 507-514
-
-
Van Rompaey, L.1
Ayoubi, T.2
Van De Ven, W.3
Marynen, P.4
-
30
-
-
4344716372
-
Inhibition of furin by polyarginine-containing peptides: Nanomolar inhibition by nona-d-arginine
-
Kacprzak MM, Peinado JR, Than ME, Appel J, Henrich S, Lipkind G, Houghten RA, Bode W & Lindberg I (2004) Inhibition of furin by polyarginine- containing peptides: nanomolar inhibition by nona-d-arginine. J Biol Chem 279, 36788-36794.
-
(2004)
J Biol Chem
, vol.279
, pp. 36788-36794
-
-
Kacprzak, M.M.1
Peinado, J.R.2
Than, M.E.3
Appel, J.4
Henrich, S.5
Lipkind, G.6
Houghten, R.A.7
Bode, W.8
Lindberg, I.9
-
31
-
-
0037743535
-
The crystal structure of the proprotein processing proteinase furin explains its stringent specificity
-
Henrich S, Cameron A, Bourenkov GP, Kiefersauer R, Huber R, Lindberg I, Bode W & Than ME (2003) The crystal structure of the proprotein processing proteinase furin explains its stringent specificity. Nat Struct Biol 10, 520-526.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 520-526
-
-
Henrich, S.1
Cameron, A.2
Bourenkov, G.P.3
Kiefersauer, R.4
Huber, R.5
Lindberg, I.6
Bode, W.7
Than, M.E.8
-
32
-
-
0032500530
-
Identification of inhibitors of prohormone convertases 1 and 2 using a peptide combinatorial library
-
Apletalina E, Appel J, Lamango NS, Houghten RA & Lindberg I (1998) Identification of inhibitors of prohormone convertases 1 and 2 using a peptide combinatorial library. J Biol Chem 273, 26589-26595.
-
(1998)
J Biol Chem
, vol.273
, pp. 26589-26595
-
-
Apletalina, E.1
Appel, J.2
Lamango, N.S.3
Houghten, R.A.4
Lindberg, I.5
-
33
-
-
0028237286
-
The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2
-
Martens GJ, Braks JA, Eib DW, Zhou Y & Lindberg I (1994) The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2. Proc Natl Acad Sci USA 91, 5784-5787.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5784-5787
-
-
Martens, G.J.1
Braks, J.A.2
Eib, D.W.3
Zhou, Y.4
Lindberg, I.5
-
34
-
-
0029054053
-
Identification of the region within the neuroendocrine polypeptide 7B2 responsible for the inhibition of prohormone convertase PC2
-
van Horssen AM, van den Hurk WH, Bailyes EM, Hutton JC, Martens GJ & Lindberg I (1995) Identification of the region within the neuroendocrine polypeptide 7B2 responsible for the inhibition of prohormone convertase PC2. J Biol Chem 270, 14292-14296.
-
(1995)
J Biol Chem
, vol.270
, pp. 14292-14296
-
-
Van Horssen, A.M.1
Van Den Hurk, W.H.2
Bailyes, E.M.3
Hutton, J.C.4
Martens, G.J.5
Lindberg, I.6
-
35
-
-
0029954032
-
Internal cleavage of the inhibitory 7B2 carboxyl-terminal peptide by PC2: A potential mechanism for its inactivation
-
Zhu X, Rouille Y, Lamango NS, Steiner DF & Lindberg I (1996) Internal cleavage of the inhibitory 7B2 carboxyl-terminal peptide by PC2: a potential mechanism for its inactivation. Proc Natl Acad Sci USA 93, 4919-4924.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4919-4924
-
-
Zhu, X.1
Rouille, Y.2
Lamango, N.S.3
Steiner, D.F.4
Lindberg, I.5
-
36
-
-
0028107656
-
Intracellular trafficking and activation of the furin proprotein convertase: Localization to the TGN and recycling from the cell surface
-
Molly SS, Thomas L, Vanslyke JK, Stenberg PE & Thomas G (1994) Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface. EMBO J 13, 18-33.
-
(1994)
EMBO J
, vol.13
, pp. 18-33
-
-
Molly, S.S.1
Thomas, L.2
Vanslyke, J.K.3
Stenberg, P.E.4
Thomas, G.5
-
37
-
-
0027503065
-
Anti-histone autoantibodies react specifically with the B cell surface
-
Mecheri S, Dannecker G, Dennig D, Poncet P & Hoffmann MK (1993) Anti-histone autoantibodies react specifically with the B cell surface. Mol Immunol 30, 549-557.
-
(1993)
Mol Immunol
, vol.30
, pp. 549-557
-
-
Mecheri, S.1
Dannecker, G.2
Dennig, D.3
Poncet, P.4
Hoffmann, M.K.5
-
38
-
-
0029086911
-
Extranuclear location of histones in activated human peripheral blood lymphocytes and cultured T-cells
-
Watson K, Edwards RJ, Shaunak S, Parmelee DC, Sarraf C, Gooderham NJ & Davies DS (1995) Extranuclear location of histones in activated human peripheral blood lymphocytes and cultured T-cells. Biochem Pharmacol 50, 299-309.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 299-309
-
-
Watson, K.1
Edwards, R.J.2
Shaunak, S.3
Parmelee, D.C.4
Sarraf, C.5
Gooderham, N.J.6
Davies, D.S.7
-
39
-
-
0042327762
-
Isolation and characterisation of oncorhyncin II, a histone H1-derived antimicrobial peptide from skin secretions of rainbow trout, Oncorhynchus mykiss
-
Fernandes JM, Molle G, Kemp GD & Smith VJ (2004) Isolation and characterisation of oncorhyncin II, a histone H1-derived antimicrobial peptide from skin secretions of rainbow trout, Oncorhynchus mykiss. Dev Comp Immunol 28, 127-138.
-
(2004)
Dev Comp Immunol
, vol.28
, pp. 127-138
-
-
Fernandes, J.M.1
Molle, G.2
Kemp, G.D.3
Smith, V.J.4
-
41
-
-
0031814274
-
Potential role of epithelial cell-derived histone H1 proteins in innate antimicrobial defense in the human gastrointestinal tract
-
Rose FR, Bailey K, Keyte JW, Chan WC, Greenwood D & Mahida YR (1998) Potential role of epithelial cell-derived histone H1 proteins in innate antimicrobial defense in the human gastrointestinal tract. Infect Immun 66, 3255-3263.
-
(1998)
Infect Immun
, vol.66
, pp. 3255-3263
-
-
Rose, F.R.1
Bailey, K.2
Keyte, J.W.3
Chan, W.C.4
Greenwood, D.5
Mahida, Y.R.6
-
43
-
-
0042471958
-
The role of non-chromosomal histones in the host defense system
-
Kanai Y (2003) The role of non-chromosomal histones in the host defense system. Microbiol Immunol 47, 553-556.
-
(2003)
Microbiol Immunol
, vol.47
, pp. 553-556
-
-
Kanai, Y.1
-
44
-
-
0037092507
-
Extracellular matrix histone H1 binds to perlecan, is present in regenerating skeletal muscle and stimulates myoblast proliferation
-
Henriquez JP, Casar JC, Fuentealba L, Carey DJ & Brandan E (2002) Extracellular matrix histone H1 binds to perlecan, is present in regenerating skeletal muscle and stimulates myoblast proliferation. J Cell Sci 115, 2041-2051.
-
(2002)
J Cell Sci
, vol.115
, pp. 2041-2051
-
-
Henriquez, J.P.1
Casar, J.C.2
Fuentealba, L.3
Carey, D.J.4
Brandan, E.5
-
45
-
-
0027482445
-
Activation of calmodulin-dependent enzymes can be selectively inhibited by histone H1
-
Rasmussen C & Garen C (1993) Activation of calmodulin-dependent enzymes can be selectively inhibited by histone H1. J Biol Chem 268, 23788-23791.
-
(1993)
J Biol Chem
, vol.268
, pp. 23788-23791
-
-
Rasmussen, C.1
Garen, C.2
-
46
-
-
20744452340
-
Histone H1 proteins act as receptors for the 987P fimbriae of enterotoxigenic Escherichia coli
-
Zhu G, Chen H, Choi BK, Del Piero F & Schifferli DM (2005) Histone H1 proteins act as receptors for the 987P fimbriae of enterotoxigenic Escherichia coli. J Biol Chem 280, 23057-23065.
-
(2005)
J Biol Chem
, vol.280
, pp. 23057-23065
-
-
Zhu, G.1
Chen, H.2
Choi, B.K.3
Del Piero, F.4
Schifferli, D.M.5
-
47
-
-
19644400009
-
The histone H1 C-terminal domain binds to the apoptotic nuclease, DNA fragmentation factor (DFF40/CAD) and stimulates DNA cleavage
-
Widlak P, Kalinowska M, Parseghian MH, Lu X, Hansen JC & Garrard WT (2005) The histone H1 C-terminal domain binds to the apoptotic nuclease, DNA fragmentation factor (DFF40/CAD) and stimulates DNA cleavage. Biochemistry 44, 7871-7878.
-
(2005)
Biochemistry
, vol.44
, pp. 7871-7878
-
-
Widlak, P.1
Kalinowska, M.2
Parseghian, M.H.3
Lu, X.4
Hansen, J.C.5
Garrard, W.T.6
|