The immunosuppressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 8, 2000, Pages 4285-4290

  Majewski, Miroslaw ^a   Korecka, Magdalena ^a   Kossev, Plamen ^a   Li, Shiyong ^a   Goldman, June ^a   Moore, Jonni ^a   Silberstein, Leslie E ^a   Nowell, Peter C ^a   Schuler, Walter ^b   Shaw, Leslie M ^a   Wasik, Mariusz A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MACROLIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL GROWTH; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; EPSTEIN BARR VIRUS; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOPROLIFERATIVE DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR REGRESSION;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL DIVISION; CELL LINE, TRANSFORMED; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LYMPHOPROLIFERATIVE DISORDERS; MICE; MICE, INBRED ICR; MICE, SCID; NEOPLASM TRANSPLANTATION; SIROLIMUS; TRANSPLANTATION;

ANIMALIA; HUMAN HERPESVIRUS 4;

EID: 0034636055     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.080068597     Document Type: Article

References (40)

1. Morrison, V., Dunn, D. L., Manivel, C. Gajl-Peczalska, K. J. & Peterson, B. A. (1994) Am. J. Med. 97, 14-24.
2. Warnke, R. A., Weiss, L. M., Chan, J. K. C., Cleary, M. L. & Dorfman, R. F. (1995) Armed Forces Inst. Pathol. Fascicle 14, 531-535.
3. Curtis, R. E., Travis, L. B., Rowlings, P. A., Socié, G., Douglas, W., Kingma, D. W., Banks, P. M., Jaffe, E. S., Sale, G. E., Horowitz, M. M., et al. (1994) Blood 94, 2208-2216.
4. Harris, N. L., Ferry, J. A. & Swierdlow, S. H. (1997) Semin. Diagn. Pathol. 14, 8-14.
5. Gummert, J. F., Ikonen, T. & Morris, R. E. (1999) J. Am. Soc. Nephrol. 10, 1366-1380.
6. Schuurman, H. J., Cottens, S., Fuchs, S., Joergensen, J., Meerloo, T., Sedrani, R., Tanner, M., Zenke, G. & Schuler, W. (1997) Transplantation 64, 32-35.
7. Schuler, W., Sedrani, R., Cottens, S., Haberlin, B., Schulz, M., Schuurman, H. J., Zenke, G., Zerwes, H. G. & Schreier, M. H. (1997) Transplantation 64, 36-42.
8. Sedrani, R., Cottens, S., Kallen, J. & Schuler, W. (1998) Transplant. Proc. 30, 2192-2194.
9. Schuurman, H. J., Schuler, W., Ringers, J. & Jonker, M. (1998) Transplant. Proc. 30, 2198-2199.
10. Hausen, B., Boeke, K., Berry, G. J., Segarra, I. T., Christians, U. & Morri, R. E. (1999) J. Heart Lung Transplant. 18, 150-159.
11. Seghal, S. N. (1998) Clin. Biochem. 31, 335-340.
12. Sakata, A., Kuwahara, K., Ohmura, T., Inui, S. & Sakaguchi, N. (1999) Immunol. Lett. 68, 301-319.
13. Terada, N., Lucas, J. J., Szepesi, A., Franklin, R. A., Domenico, J. & Gelfand, E. W. (1993) J. Cell. Physiol. 154, 7-15.
14. Flanagan, W. M. & Crabtree, G. R. (1993) Ann. N.Y. Acad. Sci. 696, 31-37.
15. Silberstein, L. E., Jefferies, L. C., Goldman, J., Friedman, D., Moore, J. S., Nowell, P. C., Roelcke, D., Pruzanski, W., Roudier, J. & Silverman, G. J. (1991) Blood 78, 2372-2386.
16. Zhang, Q., Nowak, I., Vonderheid, E. C., Rook, A. H., Kadin, M. E., Nowell, P. C., Shaw, L. M. & Wasik, M. A. (1996) Proc. Natl. Acad. Sci. USA 93, 9148-9153.
17. Cesarman, E., Moore, P. S., Rao, P. H., Inghirami, G., Knowles, D. M. & Chang, Y. (1995) Blood 86, 2708-2714.
18. Zhang, Q., Lee, B., Korecka, M., Li, G., Weyland, C., Eck, S., Gessain, A., Arima, N., Shaw, L., Luger, S., et al. (1999) Leukemia Res. 23, 373-384.
19. Kawamata, S., Sakaida, H., Hori, T., Maeda, M. & Uchiyama, T. (1998) Blood 91, 561-569.
20. Pepper, C., Thomas, A., Tucker, H., Hoy, T. & Bentley, P. (1998) Leuk. Res. 22, 439-444.
21. Douglas, R. S., Pletcher, C. H., Jr., Nowell, P. C. & Moore, J. S. (1998) Cytometry 32, 57-65.
22. Wasik, M. A., Sioutos, N., Tuttle, M., Butmarc, J. R., Kaplan, W. & Kadin, M. E. (1994) Am. J. Pathol. 144, 1089-1097.
23. Pasqualucci, L., Wasik, M. A., Teicher, B., Flenghi, L., Bolognesi, A., Stirpe, F., Polito, L., Falini, B. & Kadin, M. E. (1995) Blood 85, 2139-2146.
24. Visonneau, S., Cesano, A., Torosian, M. H., Miller, E. J. & Santoli D. (1998) Am. J. Pathol. 152, 1299-1311.
25. Bohler, T., Waiser, J., Budde, K., Lichter, S., Jauho, A., Pritsche, L., Korn, A. & Neumayer, H. H. (1998) Transplant. Proc. 30, 2195-2197.
26. Gottschalk, A. R., Boise, L. H., Thompson, C. B. & Quintans, J. (1994) Proc. Natl. Acad. Sci. USA 91, 7350-7354.
27. Muthukkumar, S., Ramesh, T. M. & Bondada, S. (1995) Transplantation 60, 264-270.
28. Shi, Y., Frankel, A., Radvanyi, L. G., Penn, L. Z., Miller, R. G. & Mills, G. B. (1995) Cancer Res. 55, 1982-1988.
29. Hosoi, H., Dilling, M. B., Shikata, T., Liu, L. N., Shu, L., Ashmun, R. A., Germain, G. S., Abraham, R. T. & Houghton, P. J. (1999) Cancer Res. 59, 886-894.
30. Beatty, P. R., Krams, S. M., Esqiuvel, C. O. & Martinez, O. M. (1998) Transplantation 65, 1248-1255.
31. Miki, T., Goller, A., Rao, A., Wang, X., Yin, W. Y., Tandin, A., Fung, J. J., Starzl, T. E. & Valdivia, L. A. (1998) Transplant. Proc. 30, 1091-1092.
32. Khanna, R., Bell, S., Sherritt, M., Galbraith, A., Burrows, S. R., Rafter, L., Clarke, B., Slaughter, R., Falk, M. C., Douglass, J., et al. (1999) Proc. Natl. Acad. Sci. USA 96, 10391-10396.
33. Gustafsson, A., Levitsky, V., Zou, J.-Z., Frisan, T., Dalianis, T., Ljungman, P., Ringden, O., Winiarski, J., Ernberg, I. & Masucci, M. G. (2000) Blood 95, 807-814.
34. Rochford, R., Cannon, M. J., Sabbe, R. E., Adusumilli, K., Picchio, G., Glynn, J. M., Noonan, D. J., Mosier, D. E. & Hobbs, M. V. (1997) Viral Immunol. 10, 183-195.
35. Mosialos, G., Birkenbach, M., Yalamanchili, R., VanArsdale, T., Ware, C. & Kieff, E. (1995) Cell 80, 389-399.
36. Devergne, O., McFarland, E. C., Mosialos, G., Izumi, K. M., Ware, C. F. & Kieff, E. (1998) J. Virol. 72, 7900-7908.
37. Liebowitz, D. (1998) N. Eng. J. Med. 338, 1413-1421.
38. Eliopoulos, A. G., Dawson, C. W., Mosialos, G., Floettmann, J. E., Rowe, M., Armitage, R. J., Dawson, J., Zapata, J. M., Kerr, D. J., Wakelam, M. J., et al. (1996) Oncogene 13, 2243-2254.
39. Pullen, S. S., Miller, H. G., Everdeen, D. S., Dang, T. T. A., Crute, J. J. & Kehry, M. R. (1998) Biochemistry 37, 11836-11845.
40. Rochford, R., Miller, C. L., Cannon, M. J., Izumi, K. M., Kieff, E. & Longnecker, R. (1997) Arch. Virol. 142, 707-720.