Treatment of refractory Evans' syndrome with cyclosporine and prednisone

Pediatrics International

Volumn 41, Issue 1, 1999, Pages 104-107

  Uçar, Birsen ^a   Akgün, Nejat ^a   Aydoǧdu, Sultan Durmuş ^a   Kirel, Birgül ^a   Idem, Şadi ^a  

^a ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

Author keywords

Cyclosporine; Evans' syndrome; Prednisone

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CYCLOSPORIN; HEMOGLOBIN; HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN; METHYLPREDNISOLONE; PREDNISONE;

ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; CASE REPORT; CHILD; COOMBS TEST; ECCHYMOSIS; EPISTAXIS; GINGIVA BLEEDING; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; INTRAVENOUS DRUG ADMINISTRATION; LYMPHADENOPATHY; MALE; NEUTROPENIA; ORAL DRUG ADMINISTRATION; PETECHIA; PRIORITY JOURNAL; SPLENECTOMY; THROMBOCYTE COUNT; THROMBOCYTOPENIA; TRANSFUSION;

ANEMIA, HEMOLYTIC, AUTOIMMUNE; ANTI-INFLAMMATORY AGENTS; CHILD; COOMBS' TEST; CYCLOSPORINE; DRUG THERAPY, COMBINATION; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOSUPPRESSIVE AGENTS; MALE; NEUTROPENIA; PREDNISONE; SPLENECTOMY; SYNDROME; THROMBOCYTOPENIA;

EID: 0033040508     PISSN: 13288067     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1442-200x.1999.01004.x     Document Type: Article

References (10)

1. Wang WC. Evans' syndrome in childhood: pathophysiology, clinical course and treatment. Am. J. Pediatr. Hematol. Oncol. 1988; 10: 330-8.
2. Schreiber AD, Gill FM, Manno CS. Autoimmune hemolytic anemia: Immune pancytopenia. In: Nathan DG, Oski FA, eds. Hematology of Infancy and Childhood, 4th edn., Vol. 1 WB Saunders Company, Mexico, 1993; 506-7.
3. Rackoff WR, Manno CS. Treatment of refractory Evans' syndrome with alternate-day cyclosporine and prednisone. Am. J. Pediatr. Hematol. Oncol. 1994; 16: 156-9.
4. Scaradavou A, Bussell J. Evans' syndrome. Results of a pilot study utilizing a multiagent treatment protocol. Am. J. Pediatr. Hematol. Oncol. 1995; 17: 290-5.
5. Wang W, Herrod H, Pui CH, Presbury G, Wilimas J. Immunoregulatory abnormalities in Evans' syndrome. Am. J. Hematol. 1983; 15: 381-90.
6. Sullivan KM, Witherspoon RP, Storb R et al. Alternating-day cyclosporine and prednisone for treatment of high-risk chronic graft-v-host disease. Blood. 1988; 72: 555-61.
7. Hershko C, Sonnenblick M, Ashkenazi J. Control of steroid-resistant autoimmune haemolytic anaemia by cyclosporine. Br. J. Haematol. 1990; 76: 436-7.
8. Dündar S, Özdemir O, Özcebe O. Cyclosporine in steroid resistant auto-immune haemolytic anaemia. Acta Haematol. 1991; 86: 200-2.
9. Feutren G, Mihatsch MJ. Risk factors for cyclosporine-induced nephropathy in patients with autoimmune diseases. N. Eng. J. Med. 1992; 326: 1654-60.
10. Hoyer PF, Offner G, Wonigeit K, Brodehl J, Pichlmayr R. Dosage of cyclosporine A in children with renal transplants. Clin. Nephrol. 1984; 22: 68-71.