-
2
-
-
0023257041
-
History of parkinsonism
-
DUVOISIN RC: History of parkinsonism. Pharmacol. Ther. (1987) 32:1-17.
-
(1987)
Pharmacol. Ther.
, vol.32
, pp. 1-17
-
-
Duvoisin, R.C.1
-
4
-
-
0014673226
-
Modification of Parkinsonism - Chronic treatment with L-dopa
-
COTZIAS GC, PAPAVASILIOU PS, GELLENE R: Modification of Parkinsonism - chronic treatment with L-dopa. N. Engl. J. Med. (1969) 280:337-345.
-
(1969)
N. Engl. J. Med.
, vol.280
, pp. 337-345
-
-
Cotzias, G.C.1
Papavasiliou, P.S.2
Gellene, R.3
-
5
-
-
20444489689
-
Motor fluctuations and dyskinesias in Parkinsons disease: Clinical manifestations
-
JANKOVIC J: Motor fluctuations and dyskinesias in Parkinsons disease: clinical manifestations. Mov. Disord. (2005) 20(Suppl. 11):S11-S16.
-
(2005)
Mov. Disord.
, vol.20
, Issue.SUPPL. 11
-
-
Jankovic, J.1
-
7
-
-
14944354884
-
Sydney Multicenter Study of Parkinson's disease: Non-L-dopa-responsive problems dominate at 15 years
-
HELY MA, MORRIS JG, REID WG, TRAFFICANTE R: Sydney Multicenter Study of Parkinson's disease: non-L-dopa-responsive problems dominate at 15 years. Mov. Disord. (2005) 20:190-199.
-
(2005)
Mov. Disord.
, vol.20
, pp. 190-199
-
-
Hely, M.A.1
Morris, J.G.2
Reid, W.G.3
Trafficante, R.4
-
8
-
-
23144455501
-
Neurodegenerative disorders: Parkinsons disease and Huntington's disease
-
HAGUE SM, KLAFFKE S, BANDMANN O: Neurodegenerative disorders: Parkinsons disease and Huntington's disease. J. Neurol. Neurosurg. Psychiatry (2005) 76:1058-1063.
-
(2005)
J. Neurol. Neurosurg. Psychiatry
, vol.76
, pp. 1058-1063
-
-
Hague, S.M.1
Klaffke, S.2
Bandmann, O.3
-
10
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
KITADA I, ASAKAWA S, HATTORI N et al.: Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature (1998) 392:605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, I.1
Asakawa, S.2
Hattori, N.3
-
11
-
-
30444444255
-
Burden of illness in Parkinsons disease
-
HUSE DM, SCHULMAN K, ORSINI L, CASTELLI-HALEY J, KENNEDY S, LENHART G: Burden of illness in Parkinsons disease. Mov. Disord. (2005) 20:1449-1454.
-
(2005)
Mov. Disord.
, vol.20
, pp. 1449-1454
-
-
Huse, D.M.1
Schulman, K.2
Orsini, L.3
Castelli-Haley, J.4
Kennedy, S.5
Lenhart, G.6
-
12
-
-
2342619394
-
Effect of psychiatric and other nonmotor symptoms on disability in Parkinson's disease
-
WEINTRAUB D, MOBERG PJ, DUDA JE et al.: Effect of psychiatric and other nonmotor symptoms on disability in Parkinson's disease. J. Am. Geriatr. Soc. (2004) 52:784-788.
-
(2004)
J. Am. Geriatr. Soc.
, vol.52
, pp. 784-788
-
-
Weintraub, D.1
Moberg, P.J.2
Duda, J.E.3
-
13
-
-
0024457355
-
DATATOP: A multicenter controlled clinical trial in early Parkinson's disease
-
PARKINSON STUDY GROUP: DATATOP: a multicenter controlled clinical trial in early Parkinson's disease. Arch. Neurol. (1989) 46:1052-1060.
-
(1989)
Arch. Neurol.
, vol.46
, pp. 1052-1060
-
-
-
14
-
-
0037378740
-
Neuroprotection in Parkinson's disease: Clinical trials
-
STOCCHI F, OLANOW CW. Neuroprotection in Parkinson's disease: clinical trials. Ann. Neurol. (2003) 53(Suppl. 3):S87-S99.
-
(2003)
Ann. Neurol.
, vol.53
, Issue.SUPPL. 3
-
-
Stocchi, F.1
Olanow, C.W.2
-
15
-
-
0025232430
-
Parkinsons disease
-
MARSDEN CD: Parkinsons disease. Lancet (1990) 335(8695):948-952.
-
(1990)
Lancet
, vol.335
, Issue.8695
, pp. 948-952
-
-
Marsden, C.D.1
-
16
-
-
0025954066
-
Aging and Parkinsons disease: Substantia nigra regional selectivity
-
FEARNLEY JM, LEES AJ: Aging and Parkinsons disease: substantia nigra regional selectivity. Brain (1991) 114:2283-2301.
-
(1991)
Brain
, vol.114
, pp. 2283-2301
-
-
Fearnley, J.M.1
Lees, A.J.2
-
18
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
DAWSON TM, DAWSON VL: Molecular pathways of neurodegeneration in Parkinson's disease. Science (2003) 302:819-822.
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
19
-
-
5644228612
-
PINK, PANK or PARK? a clinicians' guide to familial parkinsonism
-
HEALY DG, ABOU-SLEIMAN PM, WOOD NW: PINK, PANK or PARK? A clinicians' guide to familial parkinsonism. Lancet Neurol. (2004) 3:652-672.
-
(2004)
Lancet Neurol.
, vol.3
, pp. 652-672
-
-
Healy, D.G.1
Abou-Sleiman, P.M.2
Wood, N.W.3
-
20
-
-
0042521076
-
The environment and Parkinson's disease: Is the nigrostriatal system preferentially targeted by neurotoxins?
-
DI MONTE DA: The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins? Lancet Neurol. (2003) 2:531-538.
-
(2003)
Lancet Neurol.
, vol.2
, pp. 531-538
-
-
Di Monte, D.A.1
-
21
-
-
18844394828
-
Pathogenesis of nigral cell death in Parkinson's disease
-
PRZEDBORSKI S: Pathogenesis of nigral cell death in Parkinson's disease. Parkinsonism Relat. Disord. (2005) 11(Suppl. 1):S3-S7.
-
(2005)
Parkinsonism Relat. Disord.
, vol.11
, Issue.SUPPL. 1
-
-
Przedborski, S.1
-
22
-
-
2442570592
-
Disease modification in Parkinson's disease
-
SCHAPIRA AH: Disease modification in Parkinson's disease. Lancet Neurol. (2004) 3:362-368.
-
(2004)
Lancet Neurol.
, vol.3
, pp. 362-368
-
-
Schapira, A.H.1
-
23
-
-
0024848034
-
Abnormalities of the electron transport chain in idiopathic Parkinsons disease
-
PARKER WD Jr, BOYSON SJ, PARKS JK: Abnormalities of the electron transport chain in idiopathic Parkinsons disease. Ann. Neurol. (1989) 26:719-723.
-
(1989)
Ann. Neurol.
, vol.26
, pp. 719-723
-
-
Parker Jr., W.D.1
Boyson, S.J.2
Parks, J.K.3
-
24
-
-
0024390719
-
Mitochondrial complex I deficiency in Parkinson's disease
-
SCHAPIRA AH, COOPER JM, DEXTER D et al.: Mitochondrial complex I deficiency in Parkinson's disease. Lancet (1989) 1(8649):1269.
-
(1989)
Lancet
, vol.1
, Issue.8649
, pp. 1269
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
-
25
-
-
29644434199
-
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant α-synuclein-induced toxicity
-
SMITH WW, JIANG H, PEI Z et al.: Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant α-synuclein-induced toxicity. Hum. Mol. Genet. (2005) 14:3801-3811.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 3801-3811
-
-
Smith, W.W.1
Jiang, H.2
Pei, Z.3
-
26
-
-
0034090891
-
AMPA receptor blockade improves levodopa-induced dyskinesia in MPTP monkeys
-
KONITSIOTIS S, BLANCHET PJ, VERHAGEN L et al.: AMPA receptor blockade improves levodopa-induced dyskinesia in MPTP monkeys. Neurology (2000) 54:1589-1595.
-
(2000)
Neurology
, vol.54
, pp. 1589-1595
-
-
Konitsiotis, S.1
Blanchet, P.J.2
Verhagen, L.3
-
27
-
-
27644531857
-
A possible role for humoral immunity in the pathogenesis of Parkinson's disease
-
ORR CF, ROWE DB, MIZUNO Y et al.: A possible role for humoral immunity in the pathogenesis of Parkinson's disease. Brain (2005) 128:2665-2674.
-
(2005)
Brain
, vol.128
, pp. 2665-2674
-
-
Orr, C.F.1
Rowe, D.B.2
Mizuno, Y.3
-
28
-
-
13144258735
-
Microglial activation and dopamine terminal loss in early Parkinson's disease
-
OUCHI Y, OSHIKAWA E, SEKINE Y et al.: Microglial activation and dopamine terminal loss in early Parkinson's disease. Ann. Neurol. (2005) 57:168-175.
-
(2005)
Ann. Neurol.
, vol.57
, pp. 168-175
-
-
Ouchi, Y.1
Oshikawa, E.2
Sekine, Y.3
-
29
-
-
0041653249
-
Nonsteroidal anti-inflammatory drugs and the risk of Parkinson's disease
-
CHEN H, ZHANG SM, HERNAN MA et al.: Nonsteroidal anti-inflammatory drugs and the risk of Parkinson's disease. Arch. Neurol. (2003) 60:1059-1064.
-
(2003)
Arch. Neurol.
, vol.60
, pp. 1059-1064
-
-
Chen, H.1
Zhang, S.M.2
Hernan, M.A.3
-
30
-
-
28544451467
-
Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease
-
CHEN H, JACOBS E, SCHWARZSCHILD MA et al.: Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease. Ann. Neurol. (2005) 58:963-967.
-
(2005)
Ann. Neurol.
, vol.58
, pp. 963-967
-
-
Chen, H.1
Jacobs, E.2
Schwarzschild, M.A.3
-
31
-
-
0028795044
-
Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain
-
BECK KD, VALVERDE J, ALEXI T et al.: Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature (1995) 373:339-341.
-
(1995)
Nature
, vol.373
, pp. 339-341
-
-
Beck, K.D.1
Valverde, J.2
Alexi, T.3
-
32
-
-
0028834063
-
Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
-
TOMAC A, LINDQVIST E, LIN LF et al.: Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature (1995) 373(6512):335-339.
-
(1995)
Nature
, vol.373
, Issue.6512
, pp. 335-339
-
-
Tomac, A.1
Lindqvist, E.2
Lin, L.F.3
-
33
-
-
0030725572
-
Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease
-
BJÖRKLUND A, ROSENBLAD C, WINKLER C, KIRIK D: Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease. Neurobiol. Dis. (1997) 4:186-200.
-
(1997)
Neurobiol. Dis.
, vol.4
, pp. 186-200
-
-
Björklund, A.1
Rosenblad, C.2
Winkler, C.3
Kirik, D.4
-
34
-
-
0032125462
-
Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons
-
HORGER BA, NISHIMURA MC, ARMANINI MP et al.: Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. J. Neurosci. (1998) 18:4929-4937.
-
(1998)
J. Neurosci.
, vol.18
, pp. 4929-4937
-
-
Horger, B.A.1
Nishimura, M.C.2
Armanini, M.P.3
-
35
-
-
0036462452
-
Neuroimmunophilin ligands in the treatment of Parkinson's disease
-
GOLD BG, NUTT JG: Neuroimmunophilin ligands in the treatment of Parkinson's disease. Curr. Opin. Pharmacol. (2002) 2:82-86.
-
(2002)
Curr. Opin. Pharmacol.
, vol.2
, pp. 82-86
-
-
Gold, B.G.1
Nutt, J.G.2
-
36
-
-
0037461309
-
Neuroprotective agents for clinical trials in Parkinsons disease: A systematic assessment
-
RAVINA BM, FAGAN SC, HART RG et al.: Neuroprotective agents for clinical trials in Parkinsons disease: a systematic assessment. Neurology (2003) 60:1234-1240.
-
(2003)
Neurology
, vol.60
, pp. 1234-1240
-
-
Ravina, B.M.1
Fagan, S.C.2
Hart, R.G.3
-
37
-
-
4544326052
-
Transdermal lisuride delivery in the treatment of Parkinson's disease
-
WOITALLA D, MULLER T, BENZ S et al.: Transdermal lisuride delivery in the treatment of Parkinson's disease. J. Neural Transm. Suppl. (2004) 68:89-95.
-
(2004)
J. Neural Transm. Suppl.
, vol.68
, pp. 89-95
-
-
Woitalla, D.1
Muller, T.2
Benz, S.3
-
39
-
-
3242763710
-
Pergolide use in Parkinson's disease is associated with cardiac valve regurgitation
-
BASEMAN DG, O'SUILLEABHAIN PE, REIMOLD SC et al.: Pergolide use in Parkinson's disease is associated with cardiac valve regurgitation. Neurology (2004) 63:301-304.
-
(2004)
Neurology
, vol.63
, pp. 301-304
-
-
Baseman, D.G.1
O'Suilleabhain, P.E.2
Reimold, S.C.3
-
40
-
-
34249945382
-
Investigational pharmacological treatments for Parkinson's disease
-
Pahwa R, Lyons KE, Koller WC (Eds.), Marcel Dekker, New York
-
ONDO W: Investigational pharmacological treatments for Parkinson's disease. In: Handbook of Parkinson's disease. Pahwa R, Lyons KE, Koller WC (Eds.), Marcel Dekker, New York (2003):453-461.
-
(2003)
Handbook of Parkinson's Disease
, pp. 453-461
-
-
Ondo, W.1
-
41
-
-
0035353743
-
Transdermal dopaminergic D(2) receptor agonist therapy in Parkinson's disease with N-0923 TDS: A double-blind, placebo-controlled study
-
HUTTON JT, METMAN LV, CHASE TN et al.: Transdermal dopaminergic D(2) receptor agonist therapy in Parkinson's disease with N-0923 TDS: a double-blind, placebo-controlled study. Mov. Disord. (2001) 16:459-463.
-
(2001)
Mov. Disord.
, vol.16
, pp. 459-463
-
-
Hutton, J.T.1
Metman, L.V.2
Chase, T.N.3
-
42
-
-
0034971541
-
Continuous transdermal dopaminergic stimulation in advanced Parkinson's disease
-
METMAN LV, GILLESPIE M, FARMER C et al.: Continuous transdermal dopaminergic stimulation in advanced Parkinson's disease. Clin. Neuropharmacol. (2001) 24:163-169.
-
(2001)
Clin. Neuropharmacol.
, vol.24
, pp. 163-169
-
-
Metman, L.V.1
Gillespie, M.2
Farmer, C.3
-
43
-
-
21544434051
-
Safety, tolerability, and efficacy of continuous transdermal dopaminergic stimulation with rotigotine patch in early-stage idiopathic Parkinson's disease
-
GÜLDENPFENNIG WM, POOLE KH, SOMMERVILLE KW, BOROOJERDI B: Safety, tolerability, and efficacy of continuous transdermal dopaminergic stimulation with rotigotine patch in early-stage idiopathic Parkinson's disease. Clin. Neuropharmacol. (2005) 28:106-110.
-
(2005)
Clin. Neuropharmacol.
, vol.28
, pp. 106-110
-
-
Güldenpfennig, W.M.1
Poole, K.H.2
Sommerville, K.W.3
Boroojerdi, B.4
-
44
-
-
4243721247
-
Efficacy and dose response of the novel transdermally applied dopamine agonist rotigotine CDS in early Parkinson's disease
-
BIANCHINE J, POOLE K, WOLTERING F: Efficacy and dose response of the novel transdermally applied dopamine agonist rotigotine CDS in early Parkinson's disease. Neurology (2002) 58(Suppl. 3):A162-A163.
-
(2002)
Neurology
, vol.58
, Issue.SUPPL. 3
-
-
Bianchine, J.1
Poole, K.2
Woltering, F.3
-
45
-
-
0346754905
-
A controlled trial of rotigotine monotherapy in early Parkinson's disease
-
PARKINSON STUDY GROUP: A controlled trial of rotigotine monotherapy in early Parkinson's disease. Arch. Neurol. (2003) 60:1721-1728.
-
(2003)
Arch. Neurol.
, vol.60
, pp. 1721-1728
-
-
-
46
-
-
7944234344
-
Efficacy, safety, and tolerability of the rotigotine transdermal patch in patients with early-stage, idiopathic Parkinson's disease: A multicenter, multinational, randomized, double-blind, placebo-controlled trial
-
WATTS RL, WENDT RL, NAUSIED B et al.: Efficacy, safety, and tolerability of the rotigotine transdermal patch in patients with early-stage, idiopathic Parkinson's disease: a multicenter, multinational, randomized, double-blind, placebo-controlled trial. Mov. Disord. (2004) 19(Suppl. 9):S258.
-
(2004)
Mov. Disord.
, vol.19
, Issue.SUPPL. 9
-
-
Watts, R.L.1
Wendt, R.L.2
Nausied, B.3
-
48
-
-
0036894795
-
A controlled trial of rasagiline in early Parkinsons disease: The TEMPO Study
-
PARKINSON STUDY GROUP: A controlled trial of rasagiline in early Parkinsons disease: the TEMPO Study. Arch. Neurol. (2002) 59:1937-1943.
-
(2002)
Arch. Neurol.
, vol.59
, pp. 1937-1943
-
-
-
49
-
-
13444302612
-
A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parkinson's disease and motor fluctuations: The PRESTO study
-
PARKINSON STUDY GROUP: A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parkinson's disease and motor fluctuations: the PRESTO study. Arch. Neurol. (2005) 62:241-248.
-
(2005)
Arch. Neurol.
, vol.62
, pp. 241-248
-
-
-
50
-
-
15844386001
-
Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): A randomised, double-blind, parallel-group trial
-
RASCOL O, BROOKS DJ, MELAMED E et al.: Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): a randomised, double-blind, parallel-group trial. Lancet (2005) 365(9463):947-954.
-
(2005)
Lancet
, vol.365
, Issue.9463
, pp. 947-954
-
-
Rascol, O.1
Brooks, D.J.2
Melamed, E.3
-
51
-
-
4043114410
-
Rasagiline treatment can improve freezing of gait in advanced Parkinson's disease; a prospective randomized, double blind, placebo and entacapone controlled study
-
GILADI N, RASCOL O, BROOKS DJ et al.: Rasagiline treatment can improve freezing of gait in advanced Parkinson's disease; a prospective randomized, double blind, placebo and entacapone controlled study. Neurology (2004) 62(Suppl. 5):A329-A330.
-
(2004)
Neurology
, vol.62
, Issue.SUPPL. 5
-
-
Giladi, N.1
Rascol, O.2
Brooks, D.J.3
-
52
-
-
0034799446
-
Safinamide (Newron Pharmaceuticals)
-
CHAZO PL: Safinamide (Newron Pharmaceuticals). Curr. Opin. Investig. Drugs (2001) 2:809-813.
-
(2001)
Curr. Opin. Investig. Drugs
, vol.2
, pp. 809-813
-
-
Chazo, P.L.1
-
53
-
-
4143093673
-
Improvement of motor function in early Parkinson's disease by safinamide
-
STOCCHI F, ARNOLD G, ONOFRJ M et al.: Improvement of motor function in early Parkinson's disease by safinamide. Neurology (2004) 63:746-748.
-
(2004)
Neurology
, vol.63
, pp. 746-748
-
-
Stocchi, F.1
Arnold, G.2
Onofrj, M.3
-
54
-
-
3142554932
-
Zydis selegiline reduces 'off' time and improves symptoms in patients with Parkinson's disease
-
SHELLENBERGER MK, CLARKE A, DONOGHUE S: Zydis selegiline reduces 'off' time and improves symptoms in patients with Parkinson's disease. Mov. Disord. (2000) 15(Suppl. 3):116.
-
(2000)
Mov. Disord.
, vol.15
, Issue.SUPPL. 3
, pp. 116
-
-
Shellenberger, M.K.1
Clarke, A.2
Donoghue, S.3
-
55
-
-
2342426425
-
Zydis selegiline reduces off time in Parkinson's disease patients with motor fluctuations: A 3-month, randomized, placebo-controlled study
-
WATERS CH, SETHI KD, HAUSER RA et al.: Zydis selegiline reduces off time in Parkinson's disease patients with motor fluctuations: a 3-month, randomized, placebo-controlled study. Mov. Disord. (2004) 19:426-432.
-
(2004)
Mov. Disord.
, vol.19
, pp. 426-432
-
-
Waters, C.H.1
Sethi, K.D.2
Hauser, R.A.3
-
56
-
-
0032706790
-
The adrenergic receptor agonist, clonidine, potentiates the anti-parkinsonian action of the selective kappa-opioid receptor agonist, enadoline, in the monoamine-depleted rat
-
HILL MP, BROTCHIE JM: The adrenergic receptor agonist, clonidine, potentiates the anti-parkinsonian action of the selective kappa-opioid receptor agonist, enadoline, in the monoamine-depleted rat. Br. J. Pharmacol. (1999) 128:1577-1585.
-
(1999)
Br. J. Pharmacol.
, vol.128
, pp. 1577-1585
-
-
Hill, M.P.1
Brotchie, J.M.2
-
57
-
-
0042474326
-
2 adrenergic receptor antagonist that reduces levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinsons disease
-
2 adrenergic receptor antagonist that reduces levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinsons disease. Mov. Disord. (2003) 18:872-883.
-
(2003)
Mov. Disord.
, vol.18
, pp. 872-883
-
-
Savola, J.M.1
Hill, M.2
Engstrom, M.3
-
58
-
-
0035404473
-
New aspects of physiological and pathophysiological functions of adenosine A2A receptor in basal ganglia
-
KASE H: New aspects of physiological and pathophysiological functions of adenosine A2A receptor in basal ganglia. Biosci. Biotechnol. Biochem. (2001) 65:1447-1457.
-
(2001)
Biosci. Biotechnol. Biochem.
, vol.65
, pp. 1447-1457
-
-
Kase, H.1
-
59
-
-
0031594271
-
Adenosine A2A antagonist: A novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys
-
KANDA T, JACKSON MJ, SMITH LA et al.: Adenosine A2A antagonist: a novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys. Ann. Neurol. (1998) 43:507-513.
-
(1998)
Ann. Neurol.
, vol.43
, pp. 507-513
-
-
Kanda, T.1
Jackson, M.J.2
Smith, L.A.3
-
60
-
-
0043126954
-
Randomized trial of the adenosine A(2A) receptor antagonist istradefylline in advanced PD
-
HAUSER RA, HUBBLE JP, TRUONG DD et al.: Randomized trial of the adenosine A(2A) receptor antagonist istradefylline in advanced PD. Neurology (2003) 61:297-303.
-
(2003)
Neurology
, vol.61
, pp. 297-303
-
-
Hauser, R.A.1
Hubble, J.P.2
Truong, D.D.3
-
61
-
-
0035874345
-
Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinsons disease
-
CHEN JF, XU K, PETZER JP et al.: Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinsons disease. J. Neurosci. (2001) 21:RC143.
-
(2001)
J. Neurosci.
, vol.21
-
-
Chen, J.F.1
Xu, K.2
Petzer, J.P.3
-
62
-
-
23644462322
-
Open-label pilot study of levetiracetam (Keppra) for the treatment of levodopa-induced dyskinesias in Parkinson's disease
-
ZESIEWICZ TA, SULLIVAN KL, MALDONADO JL et al.: Open-label pilot study of levetiracetam (Keppra) for the treatment of levodopa-induced dyskinesias in Parkinson's disease. Mov. Disord. (2005) 20:1205-1209.
-
(2005)
Mov. Disord.
, vol.20
, pp. 1205-1209
-
-
Zesiewicz, T.A.1
Sullivan, K.L.2
Maldonado, J.L.3
-
63
-
-
2342450729
-
Multicenter, open-label, trial of sarizotan in Parkinson's disease patients with levodopa-induced dyskinesias (the SPLENDID Study)
-
OLANOW CW, DAMIER P, GOETZ CG et al. Multicenter, open-label, trial of sarizotan in Parkinson's disease patients with levodopa-induced dyskinesias (the SPLENDID Study). Clin. Neuropharmacol. (2004) 27:58-62.
-
(2004)
Clin. Neuropharmacol.
, vol.27
, pp. 58-62
-
-
Olanow, C.W.1
Damier, P.2
Goetz, C.G.3
-
64
-
-
0035960558
-
Serotonin 5-HT1A agonist improves motor complications in rodent and primate parkinsonian models
-
BIBBIANI F, OH JD, CHASE TN: Serotonin 5-HT1A agonist improves motor complications in rodent and primate parkinsonian models. Neurology (2001) 57:1829-1834.
-
(2001)
Neurology
, vol.57
, pp. 1829-1834
-
-
Bibbiani, F.1
Oh, J.D.2
Chase, T.N.3
-
66
-
-
0037147130
-
K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK
-
ROUX PP, DORVAL G, BOUDREAU M et al.: K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK. J. Biol. Chem. (2002) 277:49473-49480.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49473-49480
-
-
Roux, P.P.1
Dorval, G.2
Boudreau, M.3
-
67
-
-
0030612117
-
10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects
-
10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann. Neurol. (1997) 42:261-264.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 261-264
-
-
Shults, C.W.1
Haas, R.H.2
Passov, D.3
Beal, M.F.4
-
68
-
-
0036771852
-
10 in early Parkinsons disease: Evidence of slowing of the functional decline
-
10 in early Parkinsons disease: evidence of slowing of the functional decline. Arch. Neurol. (2002) 59:1541-1550.
-
(2002)
Arch. Neurol.
, vol.59
, pp. 1541-1550
-
-
Shults, C.W.1
Oakes, D.2
Kieburtz, K.3
-
70
-
-
0037426566
-
10 supplementation provides mild symptomatic benefit in patients with Parkinsons disease
-
10 supplementation provides mild symptomatic benefit in patients with Parkinsons disease. Neurosci. Lett. (2003) 341:201-204.
-
(2003)
Neurosci. Lett.
, vol.341
, pp. 201-204
-
-
Müller, T.1
Buttner Gholipour, A.F.2
Kuhn, W.3
-
71
-
-
0032914740
-
Creatine and cyclocreatine attenuate MPTP neurotoxicity
-
MATTHEWS RT, FERRANTE RJ, KILVENYI P et al.: Creatine and cyclocreatine attenuate MPTP neurotoxicity. Exp. Neurol. (1999) 157:142-149.
-
(1999)
Exp. Neurol.
, vol.157
, pp. 142-149
-
-
Matthews, R.T.1
Ferrante, R.J.2
Kilvenyi, P.3
-
72
-
-
0141959170
-
Creatine supplementation in Huntington's disease: A placebo-controlled pilot trial
-
VERBESSEM P, LEMIERE J, EIJNDE BO et al.: Creatine supplementation in Huntington's disease: a placebo-controlled pilot trial. Neurology (2003) 61:925-930.
-
(2003)
Neurology
, vol.61
, pp. 925-930
-
-
Verbessem, P.1
Lemiere, J.2
Eijnde, B.O.3
-
73
-
-
18144370445
-
High-dose creatine therapy for Huntington's disease: A 2-year clinical and MRS study
-
TABRIZI SJ, BLAMIRE AM, MANNERS DN et al.: High-dose creatine therapy for Huntington's disease: a 2-year clinical and MRS study. Neurology (2005) 64:1655-1666.
-
(2005)
Neurology
, vol.64
, pp. 1655-1666
-
-
Tabrizi, S.J.1
Blamire, A.M.2
Manners, D.N.3
-
74
-
-
0037417220
-
Apoptosis and caspases in neurodegenerative diseases
-
FRIEDLANDER RM: Apoptosis and caspases in neurodegenerative diseases. N. Engl. J. Med. (2003) 348:1365-1375.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1365-1375
-
-
Friedlander, R.M.1
-
75
-
-
11244317215
-
The potential of minocycline for neuroprotection in human neurologic disease
-
ZEMKE D, MAJID A: The potential of minocycline for neuroprotection in human neurologic disease. Clin. Neuropharmacol. (2004) 27:293-298.
-
(2004)
Clin. Neuropharmacol.
, vol.27
, pp. 293-298
-
-
Zemke, D.1
Majid, A.2
-
76
-
-
0038249170
-
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson's disease
-
GILL SS, PATEL NK, HOTTON GR et al.: Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson's disease. Nat. Med. (2003) 9:589-595.
-
(2003)
Nat. Med.
, vol.9
, pp. 589-595
-
-
Gill, S.S.1
Patel, N.K.2
Hotton, G.R.3
-
77
-
-
33644833272
-
Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson's disease
-
LANG AE, GILL S, PATEL NK et al.: Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson's disease. Ann. Neurol. (2006) 59:459-466.
-
(2006)
Ann. Neurol.
, vol.59
, pp. 459-466
-
-
Lang, A.E.1
Gill, S.2
Patel, N.K.3
-
78
-
-
22544461907
-
Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain
-
LOVE S, PLAHA P, PATEL NK et al.: Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nat. Med. (2005) 11:703-704.
-
(2005)
Nat. Med.
, vol.11
, pp. 703-704
-
-
Love, S.1
Plaha, P.2
Patel, N.K.3
-
79
-
-
20744436538
-
Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor
-
AHN Y-H, BENSADOUN J-C, AEBISCHER P et al.: Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor. Brain Res. Bull. (2005) 66:135-142.
-
(2005)
Brain Res. Bull.
, vol.66
, pp. 135-142
-
-
Ahn, Y.-H.1
Bensadoun, J.-C.2
Aebischer, P.3
-
80
-
-
23644452944
-
Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified neurturin construct
-
FJORD-LARSEN, JOHANSEN JL, KUSK P et al.: Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified neurturin construct. Exp. Neurol. (2005) 195:49-60.
-
(2005)
Exp. Neurol.
, vol.195
, pp. 49-60
-
-
Fjord-Larsen1
Johansen, J.L.2
Kusk, P.3
-
81
-
-
0037064165
-
Subthalamic GAD gene therapy in a Parkinsons disease rat model
-
LUO J, KAPLITT MG, FITZSIMONS HL et al.: Subthalamic GAD gene therapy in a Parkinsons disease rat model. Science (2002) 298:425-429.
-
(2002)
Science
, vol.298
, pp. 425-429
-
-
Luo, J.1
Kaplitt, M.G.2
Fitzsimons, H.L.3
-
82
-
-
14244253740
-
Gene therapy for Parkinsons disease set to enter Phase I trials
-
BUTCHER J: Gene therapy for Parkinsons disease set to enter Phase I trials. Lancet Neurol. (2002) 1:462.
-
(2002)
Lancet Neurol.
, vol.1
, pp. 462
-
-
Butcher, J.1
-
83
-
-
0141940594
-
Stereotaxic intrastriatal implantation of human retinal pigment epithelial (hRPE) cells attached to gelatin microcarriers: A potential new cell therapy for Parkinsons disease
-
WATTS RL, RAISER CD, STOVER NP et al.: Stereotaxic intrastriatal implantation of human retinal pigment epithelial (hRPE) cells attached to gelatin microcarriers: a potential new cell therapy for Parkinsons disease. J. Neural Transm. Suppl. (2003) 65:215-227.
-
(2003)
J. Neural Transm. Suppl.
, vol.65
, pp. 215-227
-
-
Watts, R.L.1
Raiser, C.D.2
Stover, N.P.3
-
84
-
-
28944447738
-
Intrastriatal implantation of human retinal pigment epithelial cells attached to microcarriers in advanced Parkinsons disease
-
STOVER NP, BAKAY RAE, SUBRAMANIAN T et al.: Intrastriatal implantation of human retinal pigment epithelial cells attached to microcarriers in advanced Parkinsons disease. Arch. Neurol. (2005) 62:1833-1837.
-
(2005)
Arch. Neurol.
, vol.62
, pp. 1833-1837
-
-
Stover, N.P.1
Bakay, R.A.E.2
Subramanian, T.3
-
85
-
-
0031681206
-
Donepezil for treatment of dementia with Lewy bodies: A case series of nine patients
-
SHEA C, MACKNIGHT C, ROCKWOOD K: Donepezil for treatment of dementia with Lewy bodies: a case series of nine patients. Int. Pychogeriatr. (1998) 10:229-238.
-
(1998)
Int. Pychogeriatr.
, vol.10
, pp. 229-238
-
-
Shea, C.1
Macknight, C.2
Rockwood, K.3
-
86
-
-
0036868921
-
Worsening of motor function and mood in a patient with Parkinsons disease after pharmacologic challenge with oral rivastigmine
-
RICHARD IH, JUSTUS AW, GREIG NH et al.: Worsening of motor function and mood in a patient with Parkinsons disease after pharmacologic challenge with oral rivastigmine. Clin. Neuropharmacol. (2002) 25:296-299.
-
(2002)
Clin. Neuropharmacol.
, vol.25
, pp. 296-299
-
-
Richard, I.H.1
Justus, A.W.2
Greig, N.H.3
-
87
-
-
0142091310
-
Cognitive, psychiatric and motor response to galantamine in Parkinsons disease with dementia
-
AARSLAND D, HUTCHINSON M, LARSEN JP: Cognitive, psychiatric and motor response to galantamine in Parkinsons disease with dementia. Int. J. Geriatr. Psychiatry (2003) 18:937-941.
-
(2003)
Int. J. Geriatr. Psychiatry
, vol.18
, pp. 937-941
-
-
Aarsland, D.1
Hutchinson, M.2
Larsen, J.P.3
-
88
-
-
23644461632
-
Efficacy and safety of donepezil in the treatment of executive dysfunction in Parkinsons disease: A pilot study
-
LINAZASORO G, LASA A, VAN BLERCOM N: Efficacy and safety of donepezil in the treatment of executive dysfunction in Parkinsons disease: a pilot study. Clin. Neuropharmacol. (2005) 28:176-178.
-
(2005)
Clin. Neuropharmacol.
, vol.28
, pp. 176-178
-
-
Linazasoro, G.1
Lasa, A.2
Van Blercom, N.3
-
89
-
-
28044457416
-
Benefits of rivastigmine on attention in dementia associated with Parkinsons disease
-
WESNES KA, McKEITH I, EDGAR C et al.: Benefits of rivastigmine on attention in dementia associated with Parkinsons disease. Neurology (2005) 65:1654-1656.
-
(2005)
Neurology
, vol.65
, pp. 1654-1656
-
-
Wesnes, K.A.1
McKeith, I.2
Edgar, C.3
-
90
-
-
0036265213
-
Donepezil for cognitive impairment in Parkinsons disease: A randomised controlled study
-
AARSLAND D, LAAKE K, LARSEN JP, JANVIN C: Donepezil for cognitive impairment in Parkinsons disease: a randomised controlled study. J. Neurol. Neurosurg. Psychiatry (2002) 72:708-712.
-
(2002)
J. Neurol. Neurosurg. Psychiatry
, vol.72
, pp. 708-712
-
-
Aarsland, D.1
Laake, K.2
Larsen, J.P.3
Janvin, C.4
-
91
-
-
21344444811
-
Donepezil for dementia in Parkinsons disease: A randomised, double blind, placebo controlled, crossover study
-
RAVINA B, PUTT M, SIDEROWF A et al.: Donepezil for dementia in Parkinsons disease: a randomised, double blind, placebo controlled, crossover study. J. Neurol. Neurosurg. Psychiatry (2005) 76:934-939.
-
(2005)
J. Neurol. Neurosurg. Psychiatry
, vol.76
, pp. 934-939
-
-
Ravina, B.1
Putt, M.2
Siderowf, A.3
-
92
-
-
10044283107
-
Rivastigmine for dementia associated with Parkinson s disease
-
EMRE M, AARSLAND D, ALBANESE A et al.: Rivastigmine for dementia associated with Parkinson s disease. N. Engl. J. Med. (2004) 351:2509-2518.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2509-2518
-
-
Emre, M.1
Aarsland, D.2
Albanese, A.3
-
93
-
-
0026701318
-
Efficacy of memantine, an NMDA receptor antagonist, in the treatment of Parkinsons disease
-
RABEY JM, NISSIPEANU P, KORCZYN A: Efficacy of memantine, an NMDA receptor antagonist, in the treatment of Parkinsons disease. J. Neural Transm. Park. Dis. Dement. Sect. (1992) 4:277-282.
-
(1992)
J. Neural Transm. Park. Dis. Dement. Sect.
, vol.4
, pp. 277-282
-
-
Rabey, J.M.1
Nissipeanu, P.2
Korczyn, A.3
-
94
-
-
0032730121
-
Effect of memantine (NMDA antagonist) on Parkinson's disease: A double-blind crossover randomized study
-
MERRELLO M, NOUZEILLES MI, CAMMAROTA A, LEIGUARDA R: Effect of memantine (NMDA antagonist) on Parkinson's disease: a double-blind crossover randomized study. Clin. Neuropharmacol. (1999) 22:273-276.
-
(1999)
Clin. Neuropharmacol.
, vol.22
, pp. 273-276
-
-
Merrello, M.1
Nouzeilles, M.I.2
Cammarota, A.3
Leiguarda, R.4
-
95
-
-
3042567248
-
Memantine can relieve certain symptoms in Parkinson's disease. Improvement achieved in two out of three described cases with dyskinesia and cognitive failure
-
LOKK J: [Memantine can relieve certain symptoms in Parkinson's disease. Improvement achieved in two out of three described cases with dyskinesia and cognitive failure]. Lakartidningen (2004) 101:2003-2006.
-
(2004)
Lakartidningen
, vol.101
, pp. 2003-2006
-
-
Lokk, J.1
-
96
-
-
3442894212
-
Repetitive transcranial magnetic stimulation is as effective as fluoxetine in the treatment of depression in patients with Parkinson's disease
-
FREGNI F, SANTOS CM, MYCZKOWSKI ML et al.: Repetitive transcranial magnetic stimulation is as effective as fluoxetine in the treatment of depression in patients with Parkinson's disease. J. Neurol. Neurosurg. Psychiatry (2004) 75:1171-1174.
-
(2004)
J. Neurol. Neurosurg. Psychiatry
, vol.75
, pp. 1171-1174
-
-
Fregni, F.1
Santos, C.M.2
Myczkowski, M.L.3
-
97
-
-
4544229556
-
Citalopram treatment of depression in Parkinson's disease: The impact on anxiety, disability, and cognition
-
MENZA M, MARIN H, KAUFMAN K et al.: Citalopram treatment of depression in Parkinson's disease: the impact on anxiety, disability, and cognition. J. Neuropsychiatry Clin. Neurosci. (2004) 16:315-319.
-
(2004)
J. Neuropsychiatry Clin. Neurosci.
, vol.16
, pp. 315-319
-
-
Menza, M.1
Marin, H.2
Kaufman, K.3
-
98
-
-
0141705744
-
Does nefazodone improve both depression and Parkinsons disease? A pilot randomized trial
-
AVILA A, CARDONA X, MARTIN-BARANERA M et al.: Does nefazodone improve both depression and Parkinsons disease? A pilot randomized trial. J. Clin. Psychopharmacol. (2003) 23:509-513.
-
(2003)
J. Clin. Psychopharmacol.
, vol.23
, pp. 509-513
-
-
Avila, A.1
Cardona, X.2
Martin-Baranera, M.3
-
99
-
-
3042647039
-
Continuous apomorphine infusion (CAI) and neuropsychiatric disorders in patients with advanced Parkinsons disease: A follow-up of two years
-
MORGANTE L, BASILE G, EPIFANIO A et al.: Continuous apomorphine infusion (CAI) and neuropsychiatric disorders in patients with advanced Parkinsons disease: a follow-up of two years. Arch. Gerontol. Geriatr. Suppl. (2004) 9:291-296.
-
(2004)
Arch. Gerontol. Geriatr. Suppl.
, vol.9
, pp. 291-296
-
-
Morgante, L.1
Basile, G.2
Epifanio, A.3
-
100
-
-
20844449074
-
Long-term efficacy and safety of pramipexole in advanced Parkinson's disease: Results from a European multicenter trial
-
MOLLER JC, OERTEL WH, KOSTER J et al.: Long-term efficacy and safety of pramipexole in advanced Parkinson's disease: results from a European multicenter trial. Mov. Disord. (2005) 20:602-610.
-
(2005)
Mov. Disord.
, vol.20
, pp. 602-610
-
-
Moller, J.C.1
Oertel, W.H.2
Koster, J.3
-
101
-
-
85047693394
-
Anhedonia, depression, and motor functioning in Parkinson's disease during treatment with pramipexole
-
LEMKE MR, BRECHT HM, KOESTER J et al.: Anhedonia, depression, and motor functioning in Parkinson's disease during treatment with pramipexole. J. Neuropsychiatry Clin. Neurosci. (2005) 17:214-220.
-
(2005)
J. Neuropsychiatry Clin. Neurosci.
, vol.17
, pp. 214-220
-
-
Lemke, M.R.1
Brecht, H.M.2
Koester, J.3
-
102
-
-
1942454228
-
Sleep and fatigue in Parkinsons disease
-
FRIEDMAN JH, CHOU KL: Sleep and fatigue in Parkinsons disease. Parkinsonism Mat. Disord. (2004) 10(Suppl. 1):S27-S35.
-
(2004)
Parkinsonism Mat. Disord.
, vol.10
, Issue.SUPPL. 1
-
-
Friedman, J.H.1
Chou, K.L.2
-
103
-
-
23844533619
-
Sudden uncontrollable somnolence and medication use in Parkinson's disease
-
AVORN J, SCHNEEWEISS S, SUDARSKY LR et al.: Sudden uncontrollable somnolence and medication use in Parkinson's disease. Arch. Neurol. (2005) 62:1242-1248.
-
(2005)
Arch. Neurol.
, vol.62
, pp. 1242-1248
-
-
Avorn, J.1
Schneeweiss, S.2
Sudarsky, L.R.3
-
104
-
-
0036112840
-
Treatment of excessive daytime sleepiness in patients with Parkinsons disease with modafinil
-
NIEVES AV, LANG AE: Treatment of excessive daytime sleepiness in patients with Parkinsons disease with modafinil. Clin. Neuropharmacol. (2002) 25:111-114.
-
(2002)
Clin. Neuropharmacol.
, vol.25
, pp. 111-114
-
-
Nieves, A.V.1
Lang, A.E.2
-
105
-
-
0037114678
-
Modafinil for the treatment of daytime sleepiness in Parkinsons disease: A double-blind, randomized, crossover, placebo-controlled polygraphic trial
-
HOGL B, SALETU M, BRANDAUER E et al.: Modafinil for the treatment of daytime sleepiness in Parkinsons disease: a double-blind, randomized, crossover, placebo-controlled polygraphic trial. Sleep (2002) 25:905-909.
-
(2002)
Sleep
, vol.25
, pp. 905-909
-
-
Hogl, B.1
Saletu, M.2
Brandauer, E.3
-
106
-
-
0037355884
-
Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease
-
ADLER CH, CAVINESS JN, HENTZ JG et al.: Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease. Mov. Disord. (2003) 18:287-293.
-
(2003)
Mov. Disord.
, vol.18
, pp. 287-293
-
-
Adler, C.H.1
Caviness, J.N.2
Hentz, J.G.3
-
107
-
-
28144435110
-
Modafinil for daytime somnolence in Parkinson's disease: Double blind, placebo controlled parallel trial
-
ONDO W, FAYLE R, ATASSI F, JANKOVIC J: Modafinil for daytime somnolence in Parkinson's disease: double blind, placebo controlled parallel trial. J. Neurol. Neurosurg. Psychiatry (2005) 76:1636-1639.
-
(2005)
J. Neurol. Neurosurg. Psychiatry
, vol.76
, pp. 1636-1639
-
-
Ondo, W.1
Fayle, R.2
Atassi, F.3
Jankovic, J.4
|