메뉴 건너뛰기




Volumn 1112, Issue 1, 2006, Pages 46-55

Bcl-2 overexpression disrupts the morphology of PC12 cells through reduced ERK activation

Author keywords

Actin; Bcl 2; Cell shape; Cytoskeleton; p ERK

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACTIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BCL 2; REGULATOR PROTEIN;

EID: 33748555549     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.07.017     Document Type: Article
Times cited : (4)

References (36)
  • 1
    • 0141680604 scopus 로고    scopus 로고
    • Annexin 1 regulates cell proliferation by disruption of cell morphology and inhibition of cyclin D1 expression through sustained activation of the ERK1/2 MAPK signal
    • Alldridge L.C., and Bryant C.E. Annexin 1 regulates cell proliferation by disruption of cell morphology and inhibition of cyclin D1 expression through sustained activation of the ERK1/2 MAPK signal. Exp. Cell Res. 290 (2003) 93-107
    • (2003) Exp. Cell Res. , vol.290 , pp. 93-107
    • Alldridge, L.C.1    Bryant, C.E.2
  • 2
    • 0033549893 scopus 로고    scopus 로고
    • The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth
    • Ashcroft M., Stephens R.M., Hallberg B., Downward J., and Kaplan D.R. The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth. Oncogene 18 (1999) 4586-4597
    • (1999) Oncogene , vol.18 , pp. 4586-4597
    • Ashcroft, M.1    Stephens, R.M.2    Hallberg, B.3    Downward, J.4    Kaplan, D.R.5
  • 3
    • 0031050310 scopus 로고    scopus 로고
    • Cytoskeletal and adhesion proteins as tumor suppressors
    • Ben-Ze'ev A. Cytoskeletal and adhesion proteins as tumor suppressors. Curr. Opin. Cell Biol. 9 (1997) 99-108
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 99-108
    • Ben-Ze'ev, A.1
  • 4
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
    • Cowley S., Paterson H., Kemp P., and Marshall C.J. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77 (1994) 841-852
    • (1994) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 5
    • 0030868245 scopus 로고    scopus 로고
    • Bcl-2 overexpression enhances the metastatic potential of a human breast cancer line
    • Del Bufalo D., Biroccio A., Leonetti C., and Zupi G. Bcl-2 overexpression enhances the metastatic potential of a human breast cancer line. FASEB J. 11 (1997) 947-953
    • (1997) FASEB J. , vol.11 , pp. 947-953
    • Del Bufalo, D.1    Biroccio, A.2    Leonetti, C.3    Zupi, G.4
  • 6
    • 0033757549 scopus 로고    scopus 로고
    • Tumor suppression activity of adenovirus E1a protein: anoikis and the epithelial phenotype
    • Frisch S.M. Tumor suppression activity of adenovirus E1a protein: anoikis and the epithelial phenotype. Adv. Cancer Res. 80 (2001) 39-49
    • (2001) Adv. Cancer Res. , vol.80 , pp. 39-49
    • Frisch, S.M.1
  • 7
    • 0035181987 scopus 로고    scopus 로고
    • Bridging cytoskeletal intersections
    • Fuchs E., and Karakesisoglou I. Bridging cytoskeletal intersections. Genes Dev. 15 (2001) 1-14
    • (2001) Genes Dev. , vol.15 , pp. 1-14
    • Fuchs, E.1    Karakesisoglou, I.2
  • 8
    • 0242384809 scopus 로고    scopus 로고
    • Role of N-methyl-d-aspartate receptors in the neuroprotective activation of extracellular signal-regulated kinase 1/2 by cisplatin
    • Gozdz A., Habas A., Jaworski J., Zielinska M., Albrecht J., Chlystun M., Jalili A., and Hetman M. Role of N-methyl-d-aspartate receptors in the neuroprotective activation of extracellular signal-regulated kinase 1/2 by cisplatin. J. Biol. Chem. 278 (2003) 43663-43671
    • (2003) J. Biol. Chem. , vol.278 , pp. 43663-43671
    • Gozdz, A.1    Habas, A.2    Jaworski, J.3    Zielinska, M.4    Albrecht, J.5    Chlystun, M.6    Jalili, A.7    Hetman, M.8
  • 9
    • 0031662569 scopus 로고    scopus 로고
    • Effect of antisense mitogen-activated protein kinase oligonucleotides on rat vascular smooth muscle cell proliferation induced by EGF in vitro
    • Huang S.L., Ding B., Yu Q.S., and Guo Z.G. Effect of antisense mitogen-activated protein kinase oligonucleotides on rat vascular smooth muscle cell proliferation induced by EGF in vitro. Zhongguo Yao Li Xue Bao 19 (1998) 489-493
    • (1998) Zhongguo Yao Li Xue Bao , vol.19 , pp. 489-493
    • Huang, S.L.1    Ding, B.2    Yu, Q.S.3    Guo, Z.G.4
  • 14
    • 0035807288 scopus 로고    scopus 로고
    • Apoptosis in the absence of caspase 3
    • Liang Y., Yan C., and Schor N.F. Apoptosis in the absence of caspase 3. Oncogene 20 (2001) 6570-6578
    • (2001) Oncogene , vol.20 , pp. 6570-6578
    • Liang, Y.1    Yan, C.2    Schor, N.F.3
  • 15
    • 0036140941 scopus 로고    scopus 로고
    • Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2
    • Liang Y., Nylander K.D., Yan C., and Schor N.F. Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2. Mol. Pharmacol. 61 (2002) 142-149
    • (2002) Mol. Pharmacol. , vol.61 , pp. 142-149
    • Liang, Y.1    Nylander, K.D.2    Yan, C.3    Schor, N.F.4
  • 17
    • 13844262750 scopus 로고    scopus 로고
    • 3-nitropropionic acid-induced hydrogen peroxide, mitochondrial DNA damage, and cell death are attenuated by Bcl-2 overexpression in PC12 cells
    • Mandavilli B.S., Boldogh I., and Van Houten B. 3-nitropropionic acid-induced hydrogen peroxide, mitochondrial DNA damage, and cell death are attenuated by Bcl-2 overexpression in PC12 cells. Brain Res. Mol. Brain Res. 133 (2005) 215-223
    • (2005) Brain Res. Mol. Brain Res. , vol.133 , pp. 215-223
    • Mandavilli, B.S.1    Boldogh, I.2    Van Houten, B.3
  • 18
    • 33748566717 scopus 로고    scopus 로고
    • Bcl-2-mediated potentiation of neocarzinostatin-induced apoptosis: requirement for caspase-3, sulfhydryl groups, and cleavable Bcl-2
    • Mi Z., Hong B., Mirnics Z.K., Tyurina Y.Y., Kagan V.E., Liang Y., and Schor N.F. Bcl-2-mediated potentiation of neocarzinostatin-induced apoptosis: requirement for caspase-3, sulfhydryl groups, and cleavable Bcl-2. Cancer Chemother. (2005) 1-11
    • (2005) Cancer Chemother. , pp. 1-11
    • Mi, Z.1    Hong, B.2    Mirnics, Z.K.3    Tyurina, Y.Y.4    Kagan, V.E.5    Liang, Y.6    Schor, N.F.7
  • 19
    • 0033000299 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 enhances metastatic potential of human bladder cancer cells
    • Miyake H., Hara I., Yamanaka K., Gohji K., Arakawa S., and Kamidono S. Overexpression of Bcl-2 enhances metastatic potential of human bladder cancer cells. Br. J. Cancer 79 (1999) 1651-1656
    • (1999) Br. J. Cancer , vol.79 , pp. 1651-1656
    • Miyake, H.1    Hara, I.2    Yamanaka, K.3    Gohji, K.4    Arakawa, S.5    Kamidono, S.6
  • 21
    • 0029101360 scopus 로고
    • An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1
    • Olson M.F., Ashworth A., and Hall A. An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1. Science 269 (1995) 1270-1272
    • (1995) Science , vol.269 , pp. 1270-1272
    • Olson, M.F.1    Ashworth, A.2    Hall, A.3
  • 22
    • 0029034774 scopus 로고
    • Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor
    • Pang L., Sawada T., Decker S.J., and Saltiel A.R. Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J. Biol. Chem. 270 (1995) 13585-13588
    • (1995) J. Biol. Chem. , vol.270 , pp. 13585-13588
    • Pang, L.1    Sawada, T.2    Decker, S.J.3    Saltiel, A.R.4
  • 23
    • 0035840335 scopus 로고    scopus 로고
    • Bcl-2 blocks cisplatin-induced apoptosis by suppression of ERK-mediated p53 accumulation in B104 cells
    • Park S.A., Park H.J., Lee B.I., Ahn Y.H., Kim S.U., and Choi K.S. Bcl-2 blocks cisplatin-induced apoptosis by suppression of ERK-mediated p53 accumulation in B104 cells. Brain Res. Mol. Brain Res. 93 (2001) 18-26
    • (2001) Brain Res. Mol. Brain Res. , vol.93 , pp. 18-26
    • Park, S.A.1    Park, H.J.2    Lee, B.I.3    Ahn, Y.H.4    Kim, S.U.5    Choi, K.S.6
  • 24
    • 0035253753 scopus 로고    scopus 로고
    • Cytoskeletal changes in cell transformation and tumorigenesis
    • Pawlak G., and Helfman D.M. Cytoskeletal changes in cell transformation and tumorigenesis. Curr. Opin. Genet. Dev. 11 (2001) 41-47
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 41-47
    • Pawlak, G.1    Helfman, D.M.2
  • 26
    • 0035159826 scopus 로고    scopus 로고
    • Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations
    • Rescan C., Coutant A., Talarmin H., Theret N., Glaise D., Guguen-Guillouzo C., and Baffet G. Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations. Mol. Biol. Cell 12 (2001) 725-738
    • (2001) Mol. Biol. Cell , vol.12 , pp. 725-738
    • Rescan, C.1    Coutant, A.2    Talarmin, H.3    Theret, N.4    Glaise, D.5    Guguen-Guillouzo, C.6    Baffet, G.7
  • 28
    • 0037641217 scopus 로고    scopus 로고
    • Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases
    • Roovers K., and Assoian R.K. Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases. Mol. Cell Biol. 23 (2003) 4283-4294
    • (2003) Mol. Cell Biol. , vol.23 , pp. 4283-4294
    • Roovers, K.1    Assoian, R.K.2
  • 29
    • 0032911020 scopus 로고    scopus 로고
    • Bidirectional signaling between the cytoskeleton and integrins
    • Schoenwaelder S.M., and Burridge K. Bidirectional signaling between the cytoskeleton and integrins. Curr. Opin. Cell Biol. 11 (1999) 274-286
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 274-286
    • Schoenwaelder, S.M.1    Burridge, K.2
  • 31
    • 0026534571 scopus 로고
    • Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases
    • Thomas S.M., DeMarco M., D'Arcangelo G., Halegoua S., and Brugge J.S. Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell 68 (1992) 1031-1040
    • (1992) Cell , vol.68 , pp. 1031-1040
    • Thomas, S.M.1    DeMarco, M.2    D'Arcangelo, G.3    Halegoua, S.4    Brugge, J.S.5
  • 32
    • 0035980023 scopus 로고    scopus 로고
    • Induction of neurite outgrowth in PC12 cells by alpha-phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway
    • Tsuji M., Inanami O., and Kuwabara M. Induction of neurite outgrowth in PC12 cells by alpha-phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway. J. Biol. Chem. 276 (2001) 32779-32785
    • (2001) J. Biol. Chem. , vol.276 , pp. 32779-32785
    • Tsuji, M.1    Inanami, O.2    Kuwabara, M.3
  • 33
    • 0345498292 scopus 로고    scopus 로고
    • Bcl-2 targets the protein kinase Raf-1 to mitochondria
    • Wang H.G., Rapp U.R., and Reed J.C. Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell 87 (1996) 629-638
    • (1996) Cell , vol.87 , pp. 629-638
    • Wang, H.G.1    Rapp, U.R.2    Reed, J.C.3
  • 34
    • 0032520006 scopus 로고    scopus 로고
    • BCL-2 expression correlates with lower proliferative activity in the intermediate- and high-grade non-Hodgkin's lymphomas: an Eastern Cooperative Oncology Group and Southwest Oncology Group cooperative laboratory study
    • Winter J.N., Andersen J., Reed J.C., Krajewski S., Variakojis D., Bauer K.D., Fisher R.I., Gordon L.I., Oken M.M., Jiang S., Jeffries D., and Domer P. BCL-2 expression correlates with lower proliferative activity in the intermediate- and high-grade non-Hodgkin's lymphomas: an Eastern Cooperative Oncology Group and Southwest Oncology Group cooperative laboratory study. Blood 91 (1998) 1391-1398
    • (1998) Blood , vol.91 , pp. 1391-1398
    • Winter, J.N.1    Andersen, J.2    Reed, J.C.3    Krajewski, S.4    Variakojis, D.5    Bauer, K.D.6    Fisher, R.I.7    Gordon, L.I.8    Oken, M.M.9    Jiang, S.10    Jeffries, D.11    Domer, P.12
  • 35
    • 0026523559 scopus 로고
    • Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
    • Wood K.W., Sarnecki C., Roberts T.M., and Blenis J. Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell 68 (1992) 1041-1050
    • (1992) Cell , vol.68 , pp. 1041-1050
    • Wood, K.W.1    Sarnecki, C.2    Roberts, T.M.3    Blenis, J.4
  • 36
    • 24044458222 scopus 로고    scopus 로고
    • Bcl-2 positively regulates Sox9-dependent chondrocyte gene expression by suppressing the MEK-ERK1/2 signaling pathway
    • Yagi R., McBurney D., and Horton Jr. W.E. Bcl-2 positively regulates Sox9-dependent chondrocyte gene expression by suppressing the MEK-ERK1/2 signaling pathway. J. Biol. Chem. 280 (2005) 30517-30525
    • (2005) J. Biol. Chem. , vol.280 , pp. 30517-30525
    • Yagi, R.1    McBurney, D.2    Horton Jr., W.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.