-
1
-
-
0000021897
-
Methods for the study of irritation and toxicity of substances applied to the skin and mucous membranes
-
Draize JH, Woodward G, Calvery HO. Methods for the study of irritation and toxicity of substances applied to the skin and mucous membranes. J Pharmacol Exp Therapeut 1944; 82:377-390.
-
(1944)
J Pharmacol Exp Therapeut
, vol.82
, pp. 377-390
-
-
Draize, J.H.1
Woodward, G.2
Calvery, H.O.3
-
2
-
-
33645241082
-
-
Adopted 24 April. Paris: OECD
-
OECD Test Guideline 405. Adopted 24 April 2002. Paris: OECD.
-
(2002)
OECD Test Guideline 405
-
-
-
3
-
-
0035348060
-
The Draize eye test
-
Kirk Wilhelmus R. The Draize eye test. Surv Opthalmol 2001; 45:493-515.
-
(2001)
Surv Opthalmol
, vol.45
, pp. 493-515
-
-
Kirk Wilhelmus, R.1
-
4
-
-
0029312304
-
Alternative methods to animal experimentation: Scientific and ethical problems
-
Adolphe M. Alternative methods to animal experimentation: scientific and ethical problems. Bull Acad Natl Med 1995; 179:1009-1016.
-
(1995)
Bull Acad Natl Med
, vol.179
, pp. 1009-1016
-
-
Adolphe, M.1
-
5
-
-
0029436304
-
Draize test and alternatives methods for evaluating irritation from chemical substances
-
Moskalewski S, Mystkowska ET, Kiss E. Draize test and alternatives methods for evaluating irritation from chemical substances. Rocz Panstw Zakl Hig 1995; 46:163-168.
-
(1995)
Rocz Panstw Zakl Hig
, vol.46
, pp. 163-168
-
-
Moskalewski, S.1
Mystkowska, E.T.2
Kiss, E.3
-
6
-
-
0031804203
-
In vitro alternatives for ocular irritation
-
Curren RD, Harbell JW. In vitro alternatives for ocular irritation. Environ Health Perspect 1998; 106 (Suppl 2):485-492.
-
(1998)
Environ Health Perspect
, vol.106
, Issue.2 SUPPL.
, pp. 485-492
-
-
Curren, R.D.1
Harbell, J.W.2
-
7
-
-
0345768982
-
Draize rabbit eye test compatibility with eye irritation threshold in humans: A quantitative structure-activity relationship analysis
-
Abraham MH, Hassanidi M, Jalali-Heravi M, et al. Draize rabbit eye test compatibility with eye irritation threshold in humans: a quantitative structure-activity relationship analysis. Toxicol Sci 2003; 76:384-391.
-
(2003)
Toxicol Sci
, vol.76
, pp. 384-391
-
-
Abraham, M.H.1
Hassanidi, M.2
Jalali-Heravi, M.3
-
8
-
-
0018935324
-
Dose-response studies with chemical irritants in the albino rabbit eye as a basis for selecting optimum testing conditions for predicting hazard to the human eye
-
Griffith JF, Nixon GA, Bruce RD, et al. Dose-response studies with chemical irritants in the albino rabbit eye as a basis for selecting optimum testing conditions for predicting hazard to the human eye. Toxicol Appl Pharmacol 1980; 55:501-513.
-
(1980)
Toxicol Appl Pharmacol
, vol.55
, pp. 501-513
-
-
Griffith, J.F.1
Nixon, G.A.2
Bruce, R.D.3
-
10
-
-
0029130279
-
Use of clinical and consumer eye irritation data to evaluate the low-volume eye test
-
Cormier EM, Hunter JE, Bilhimer W, et al. Use of clinical and consumer eye irritation data to evaluate the low-volume eye test. J Toxicol Cutaneous Ocul Toxicol 1995; 14:197-205.
-
(1995)
J Toxicol Cutaneous Ocul Toxicol
, vol.14
, pp. 197-205
-
-
Cormier, E.M.1
Hunter, J.E.2
Bilhimer, W.3
-
11
-
-
0029895364
-
Determination of the intra- and interlaboratory reproducibility of the low-volume eye test and its statistical relationship to the Draize eye test
-
Cormier EM, Parker RD, Henson C, et al. Determination of the intra- and interlaboratory reproducibility of the low-volume eye test and its statistical relationship to the Draize eye test. Regul Toxicol Pharmacol 1996; 23:156-161.
-
(1996)
Regul Toxicol Pharmacol
, vol.23
, pp. 156-161
-
-
Cormier, E.M.1
Parker, R.D.2
Henson, C.3
-
12
-
-
0033919116
-
Eye irritation responses in rabbit and man after single applications of equal volumes of undiluted model liquid detergent products
-
Roggeband R, York M, Pericoi M, Braun W. Eye irritation responses in rabbit and man after single applications of equal volumes of undiluted model liquid detergent products. Food Chem Toxicol 2000; 38:727-734.
-
(2000)
Food Chem Toxicol
, vol.38
, pp. 727-734
-
-
Roggeband, R.1
York, M.2
Pericoi, M.3
Braun, W.4
-
13
-
-
29144487939
-
The Daize eye test and in vitro alternatives: A left-handed marriage?
-
Prinsen MK. The Daize eye test and in vitro alternatives: a left-handed marriage? Toxicol in Vitro 2006; 20:78-81. The necessity of a good standardization of the DET to validate alternative in-vitro tests is emphasized, along with the importance of the low-volume eye test.
-
(2006)
Toxicol in Vitro
, vol.20
, pp. 78-81
-
-
Prinsen, M.K.1
-
14
-
-
0034569990
-
In vitro ocular irritation toxicity study of some pesticides
-
Budai P, Vàrnagy L. In vitro ocular irritation toxicity study of some pesticides. Acta Vet Hung 2000; 48:221-228.
-
(2000)
Acta Vet Hung
, vol.48
, pp. 221-228
-
-
Budai, P.1
Vàrnagy, L.2
-
15
-
-
16244399784
-
Irritative effects of some pesticides and a technical component on tissue structure of the chorioallantoic membrane
-
Budai P, Varnagy L, Fejes S, et al. Irritative effects of some pesticides and a technical component on tissue structure of the chorioallantoic membrane. Commun Agric Appl Biol Sci 2004; 69:807-809.
-
(2004)
Commun Agric Appl Biol Sci
, vol.69
, pp. 807-809
-
-
Budai, P.1
Varnagy, L.2
Fejes, S.3
-
16
-
-
33745190026
-
The chorioallantoic membrane test as a model to predict the potential human eye irritation induced by commonly used laboratory solvents
-
Vinardell MP, Mitjans M. The chorioallantoic membrane test as a model to predict the potential human eye irritation induced by commonly used laboratory solvents. Toxicol in Vitro 2006; 20:1066-1070. The capability of the HET-CAM test is shown in predicting the eye irritation induced by industrial and laboratory solvents.
-
(2006)
Toxicol in Vitro
, vol.20
, pp. 1066-1070
-
-
Vinardell, M.P.1
Mitjans, M.2
-
17
-
-
0031052313
-
Photo hen' egg test: A model for phototoxicity
-
Neumann NJ, Holzle E, Lehmann P, et al. Photo hen' egg test: a model for phototoxicity. Br J Dermatol 1997; 136:326-330.
-
(1997)
Br J Dermatol
, vol.136
, pp. 326-330
-
-
Neumann, N.J.1
Holzle, E.2
Lehmann, P.3
-
18
-
-
0033799937
-
The quantitative chorioallantoic membrane test using trypan blue stain to predict the eye irritancy of liquid scintillation cocktails
-
Vinardell MP, Garcia L. The quantitative chorioallantoic membrane test using trypan blue stain to predict the eye irritancy of liquid scintillation cocktails. Toxicol in Vitro 2000; 14:551-555.
-
(2000)
Toxicol in Vitro
, vol.14
, pp. 551-555
-
-
Vinardell, M.P.1
Garcia, L.2
-
19
-
-
33745434690
-
In vitro quantitative determination of ophthalmic irritancy by the chorioallantoic membrane test with trypan blue staining as alternative to eye irritation test
-
in press
-
Lagarto A, Vega R, Guerra I, Gonzales R. In vitro quantitative determination of ophthalmic irritancy by the chorioallantoic membrane test with trypan blue staining as alternative to eye irritation test. Toxicol in Vitro (in press).
-
Toxicol in Vitro
-
-
Lagarto, A.1
Vega, R.2
Guerra, I.3
Gonzales, R.4
-
20
-
-
4143069348
-
Study on using the hen's egg test-chorrioallantoic membrane as an alternative method of Draize eye irritation test
-
Liao Y, Wang X, Zhang L, Li G. Study on using the hen's egg test-chorrioallantoic membrane as an alternative method of Draize eye irritation test. Wei Sheng yan jiu 2004; 33:279-283.
-
(2004)
Wei Sheng Yan Jiu
, vol.33
, pp. 279-283
-
-
Liao, Y.1
Wang, X.2
Zhang, L.3
Li, G.4
-
21
-
-
0035077815
-
Prediction of ocular irritancy of prototype shampoo formulations by the isolated rabbit eye (IRE) test and bovine corneal opacity and permeability (BCOP) assay
-
Cooper KJ, Earl LK, Harbelland J, Raabe H. Prediction of ocular irritancy of prototype shampoo formulations by the isolated rabbit eye (IRE) test and bovine corneal opacity and permeability (BCOP) assay. Toxicol in Vitro 2001; 15:95-103.
-
(2001)
Toxicol in Vitro
, vol.15
, pp. 95-103
-
-
Cooper, K.J.1
Earl, L.K.2
Harbelland, J.3
Raabe, H.4
-
22
-
-
77957178643
-
Bovine corneal opacity and permeability test: An in vitro assay of ocular irritancy
-
Gautheron P, Dukic M, Alix D, Sina JF. Bovine corneal opacity and permeability test: an in vitro assay of ocular irritancy. Fundam Appl Toxicol 1992; 18:442-449.
-
(1992)
Fundam Appl Toxicol
, vol.18
, pp. 442-449
-
-
Gautheron, P.1
Dukic, M.2
Alix, D.3
Sina, J.F.4
-
23
-
-
0028244334
-
Interlaboratory assessment of the bovine corneal opacity and permeability (BCOP) assay
-
Gautheron P, Giroux J, Cottin M, et al. Interlaboratory assessment of the bovine corneal opacity and permeability (BCOP) assay. Toxicol in Vitro 1994; 8:381-392.
-
(1994)
Toxicol in Vitro
, vol.8
, pp. 381-392
-
-
Gautheron, P.1
Giroux, J.2
Cottin, M.3
-
25
-
-
9644307886
-
Eye irritation of low-irritant cosmetic formulations: Correlation of in vitro results with clinical data and product composition
-
Debbash C, Ebenhahn C, Dami N, et al. Eye irritation of low-irritant cosmetic formulations: correlation of in vitro results with clinical data and product composition. Food Chem Toxicol 2005; 43:155-165. A comparison is carried out between HET-CAM, BCOP and a novel method using CEPI with cytotoxicity and IL-8 release as endpoints. The IL-8 assay appears the most sensitive and reliable in-vitro endpoint to predict human eye tolerance for mildly irritant chemical products.
-
(2005)
Food Chem Toxicol
, vol.43
, pp. 155-165
-
-
Debbash, C.1
Ebenhahn, C.2
Dami, N.3
-
26
-
-
20444446589
-
Performance of porcine corneal opacity and permeability assay to predict eye irritation for water-soluble cosmetic ingredients
-
Van den Berghe C, Guillet MC, Compan D. Performance of porcine corneal opacity and permeability assay to predict eye irritation for water-soluble cosmetic ingredients. Toxicol in Vitro 2005; 19:823-830. On the basis of experimental study, PCOP is confirmed to be better than BCOP as a prediction model for liquid and water-soluble cosmetic products irritancy.
-
(2005)
Toxicol in Vitro
, vol.19
, pp. 823-830
-
-
Van Den Berghe, C.1
Guillet, M.C.2
Compan, D.3
-
28
-
-
33745070230
-
Extent of corneal injury as a biomarker for hazard assessment and the development of alternative models to the Draize rabbit eye test
-
Jester JV. Extent of corneal injury as a biomarker for hazard assessment and the development of alternative models to the Draize rabbit eye test. Cutan Ocul Toxicol 2006; 25:41-54. On the basis of a comparison between the evaluation of the initial corneal injury in ex-vivo and in-vivo experiments, its importance in predicting subsequent responses and in replacing the DET is suggested.
-
(2006)
Cutan Ocul Toxicol
, vol.25
, pp. 41-54
-
-
Jester, J.V.1
-
29
-
-
0032468188
-
A new in vitro human epithelial model for assessing the eye irritating potential of formulated cosmetic products
-
Doucet O, Lanvin M, Zastrow L. A new in vitro human epithelial model for assessing the eye irritating potential of formulated cosmetic products. In Vitro Mol Toxicol J Basic Appl Res 1998; 11:273-283.
-
(1998)
In Vitro Mol Toxicol J Basic Appl Res
, vol.11
, pp. 273-283
-
-
Doucet, O.1
Lanvin, M.2
Zastrow, L.3
-
30
-
-
33645243015
-
Reconstituted human corneal epithelium: A new alternative to the Draize eye test for the assessment of the eye irritation potential of chemicals and cosmetic products
-
Doucet O, Lanvin M, Thillou C, et al. Reconstituted human corneal epithelium: a new alternative to the Draize eye test for the assessment of the eye irritation potential of chemicals and cosmetic products. Toxicol in Vitro 2006; (4):499-512. The robustness is shown of a new three-dimensional epithelial model cultivated from human corneal cells for the prediction of the potential irritancy of chemicals and complex formulated products. Good correlation between in-vivo and in-vitro results is obtained.
-
(2006)
Toxicol in Vitro
, Issue.4
, pp. 499-512
-
-
Doucet, O.1
Lanvin, M.2
Thillou, C.3
-
31
-
-
29144468687
-
Prevalidation of a new in vitro reconstituted human cornea model to assess the eye irritating potential of chemicals
-
Van Goethem F, Adriaens E, Alepee N, et al. Prevalidation of a new in vitro reconstituted human cornea model to assess the eye irritating potential of chemicals. Toxicol in Vitro 2006; 20:1-17. A high reproducibility of the results of a standardized HCE protocol obtained by different laboratories to access acute ocular irritation is presented, along with a good, but nonperfect, concordance with in-vivo classifications.
-
(2006)
Toxicol in Vitro
, vol.20
, pp. 1-17
-
-
Van Goethem, F.1
Adriaens, E.2
Alepee, N.3
-
32
-
-
0142137151
-
The immunohistochemical characterisation of an Sv 40-immortalised human corneal epithelial cell line
-
Huhtala A, Nurmi SK, Tahti H, et al. The immunohistochemical characterisation of an Sv 40-immortalised human corneal epithelial cell line. Altern Lab Anim 2003; 31:409-417.
-
(2003)
Altern Lab Anim
, vol.31
, pp. 409-417
-
-
Huhtala, A.1
Nurmi, S.K.2
Tahti, H.3
-
33
-
-
0032903944
-
Immortalized human corneal epithelial cells for ocular toxicity and inflammation studies
-
Offord EA, Sharif NA, Mace K, et al. Immortalized human corneal epithelial cells for ocular toxicity and inflammation studies. Invest Ophtalmol Vis Sci 1999; 40:1091-1101.
-
(1999)
Invest Ophtalmol Vis Sci
, vol.40
, pp. 1091-1101
-
-
Offord, E.A.1
Sharif, N.A.2
Mace, K.3
-
34
-
-
12344297471
-
Development of a sensory neuronal cell model for the estimation of mild eye irritation
-
Lilja J, Forsby A. Development of a sensory neuronal cell model for the estimation of mild eye irritation. Altern Lab Anim 2004; 3:339-343.
-
(2004)
Altern Lab Anim
, vol.3
, pp. 339-343
-
-
Lilja, J.1
Forsby, A.2
-
36
-
-
33645244277
-
Comparative study of red blood cell method in rat and calves blood as alternatives to the Draize eye irritation test
-
Lagarto A, Vega R, Vega Y, et al. Comparative study of red blood cell method in rat and calves blood as alternatives to the Draize eye irritation test. Toxicol in Vitro 2006; 20:529-533. The RBC assay using calves' blood shows better results than the RBC assay using rats' blood. In particular, a significant generation of false negative results was observed when rat blood is employed.
-
(2006)
Toxicol in Vitro
, vol.20
, pp. 529-533
-
-
Lagarto, A.1
Vega, R.2
Vega, Y.3
-
37
-
-
33646866349
-
Evaluation of eye and skin irritation of arginine-derivative surfactants using different in vitro endpoints as alternative to the in vivo assays
-
Martinez V, Corsini A, Mitjans M, et al. Evaluation of eye and skin irritation of arginine-derivative surfactants using different in vitro endpoints as alternative to the in vivo assays. Toxicol Lett 2006; 164:259-267. Differences in irritancy potential of new surfactants, not noticeable on performing a comparative DET, are detected by in-vitro models using the keratynocyte cell line NCTC 2544 and measuring different endpoints.
-
(2006)
Toxicol Lett
, vol.164
, pp. 259-267
-
-
Martinez, V.1
Corsini, A.2
Mitjans, M.3
-
38
-
-
4644346438
-
Study on the use of haemoglobin denaturation test as an alternative to Draize eye irritation test
-
Liao Y, Wang X, Zhang LS, et al. Study on the use of haemoglobin denaturation test as an alternative to Draize eye irritation test. Sichuan Da Xue Xue Bao Yi Xue Ban 2004; 35:654-657.
-
(2004)
Sichuan Da Xue Xue Bao Yi Xue Ban
, vol.35
, pp. 654-657
-
-
Liao, Y.1
Wang, X.2
Zhang, L.S.3
-
39
-
-
0037186867
-
Currently available in vitro methods used in the regulatory toxicology
-
Liebsch M, Spielmann H. Currently available in vitro methods used in the regulatory toxicology. Toxicol Lett 2002; 127:127-134.
-
(2002)
Toxicol Lett
, vol.127
, pp. 127-134
-
-
Liebsch, M.1
Spielmann, H.2
|