In vitro alternatives for ocular irritation

Environmental Health Perspectives

Volumn 106, Issue SUPPL. 2, 1998, Pages 485-492

  Curren, Rodger D ^a   Harbell, John W ^a  

^a Institute for In Vitro Sciences Inc   (United States)

Author keywords

Alternatives; Eye; In vitro; Irritation; Ocular; Toxicology

Indexed keywords

CONFERENCE PAPER; EYE IRRITATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; TOXICITY TESTING;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0031804203     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.98106485     Document Type: Conference Paper

References (28)

1. Freeberg FE, Nixon GA, Reer PJ, Weaver JE, Bruce RD, Griffith JF, Sanders LW 3d. Human and rabbit eye responses to chemical insult. Fundam Appl Toxicol 7:626-634 (1986).
2. Draize JH, Woodard G, Calvery HO. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J Pharmacol Exp Ther 82:377-390 (1944).
3. Annees I, II, III and IV to Commission Directive 93/21/EEC of 27 April 1993 adapting to technical progress for the 18th time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labeling of dangerous substances. Off J Europ Commun L110A:1-86 (1993).
4. Weil CS, Scala RA. Study of intra- and interlaboratory variability in the results of rabbit eye and skin irritation tests. Toxicol Appl Pharmacol 19:276-360 (1971).
5. Bruner LH, Carr GJ, Chamberlain M, Curren RD. Validation of alternative methods for toxicity testing. Toxicol In Vitro 10:479-501 (1996).
6. Bradlaw J, Gupta K, Green S, Hill R, Wilcox N. Practical application of non-whole animal alternatives:summary of IRAG workshop on eye irritation testing. Interagency Regulatory Alternatives Group. Food Chem Toxicol 35(1):175-178 (1997).
7. Burton ABD, York M, Lawrence RS. The in vitro assessment of severe eye irritants. Food Cosmet Toxicol 19:471-480 (1981).
8. Prinsen MK, Koëter HBWM. Justification of the enucleated eye test with eyes from slaughterhouse animals as an alternative to the Draize eye irritation test with rabbits. Food Chem Toxicol 31:69-76 (1993).
9. Lovell DP. Principal component analysis of Draize eye irritation tissue scores from 72 samples of 55 chemicals in the ECETOC data bank. Toxicol In Vitro 10:609-618 (1996).
10. Gautheron P, Dukic M, Alix D, Sina JF. Bovine corneal opacity and permeability test:an in vitro assay of ocular irritancy. Fundam Appl Toxicol 18:442-449 (1992).
11. Osborne R, Perkins MA, Roberts DA. Development and intralaboratory evaluation of an in vitro human cell-based test to aid ocular irritancy assessments. Fundam Appl Toxicol 28:139-153 (1995).
12. Kruszewski FH, Walker TL, Ward SL, Dipasquale LC. Progress in the use of human ocular tissues for in vitro alternative methods. Comments Toxicol 5:203-224 (1995).
13. De Silva O. Alternatives to eye irritation evaluation:the industry perspectives. In:Alternatives to Animal Testing (Lisansky SG, Macmillan R, Dupuis J, eds). Newbury, U.K.:PL Press, 1996;67-73.
14. Tchao R. Trans-epithelial permeability of fluorescein in vitro as an assay to determine eye irritants. In:Alternative Methods in Toxicology. Vol 6 (Goldberg AM, ed), New York: Mary Ann Liebert, 1988.
15. Shaw AJ, Clothier RH, Balls M. Loss of trans-epithelial impermeability of a confluent monolayer of Madin-Darby canine kidney (MDCK) cells as a determinant of ocular irritancy potential. ATLA 18:145-151 (1990).
16. Reader SJ, Blackwell V, O'Hara R, Clothier RH, Griffin G, Balls M. A vital dye release method for assessing the short term cytotoxic effects of chemicals and formulations. ATLA 17:28-37 (1989).
17. Borenfreund E, Puerner JA. Toxicity determined in vitro by morphological alterations and neutral red absorption. Toxicol Lett 24:119-124 (1985).
18. Harbell JW, Koontz SW, Lewis RW, Lovell D, Acosta D. IRAG working group 4. Cell cytotoxicity assays. Interagency Regulatory Alternatives Group. Food Chem Toxicol 35:79-126 (1997).
19. Pape WJW, Pfannenbecker U, Hoppe U. Validation of the red blood cell test system as an in vitro assay for the rapid screening of irritation potential of surfactants, Mol Toxicol 1:525-536 (1987).
20. Swanson JE, Donnelly TA, Harbell JW, Hugeins J. Prediction of ocular irritancy of full-strength cleaners and strippers by tissue equivalent and bovine corneal assays. J Toxicol Cut Ocular Toxicol 14:179-195 (1995).
21. Gettings SD, Lordo RA, Hintze KL, Bagley DM, Casterton PL, Chudkowski M, Curren RD, Demetrulias JL, DiPasquale LC, Earl LK et al. The CTFA evaluation of alternatives program:an evaluation of in vitro alternatives to the Draize primary eye irritation test. (Phase III). Surfactant-based formulations. Food Chem Toxicol 34:79-117 (1996).
22. Bruner LH, Carr G, Chamberlain M, Curren R. No prediction model, no validation study. ATLA 24:139-142 (1996).
23. Balls M, Botham PA, Bruner LH, Spielmann H. The EC/HO international validation study on alternatives to the Draize eye irritation test. Toxicol In Vitro 9:871-929 (1995).
24. Brantom PG, Bruner LH, Chamberlain M, De Silva O, Dupuis J, Earl LK, Louell DP, Pape WJW, Uttley M, Bagley DM et al. A summary report of the COLIPA international validation study on alternatives to the Draize rabbit eye irritation test. Toxicol In Vitro 11:141-179 (1997).
25. Luepke NP. Hen's egg chorioallantoic membrane test for irritation potential. Food Chem Toxicol 23:287-291 (1985).
26. Kristen U, Kappler R. The pollen tube growth test. In:In Vitro Testing Protocols. Methods in Molecular Biology. Vol. 43 (O'Hare S, Atterwill CK, eds). Totowa, NJ:umana Press, 1995.
27. North-Root H, Yackovich F, Demetrulias J, Gacula M, Heinze JE. Evaluation of an in vitro cell toxicity test using rabbit corneal cells to predict the eye irritation potential of surfactants. Toxicol Lett 14:207-212 (1982).
28. Bagley DM, Waters D, Kong BM. Development of a 10-day chorioallantoic membrane vascular assay as an alternative to the Draize rabbit eye irritation test. Food Chem Toxicol 32:1155-1160 (1994).