The Draize Eye Test and in vitro alternatives; a left-handed marriage?

Toxicology in Vitro

Volumn 20, Issue 1, 2006, Pages 78-81

  Prinsen, M K ^a,b  

^a TNO   (Netherlands)

^b NONE   (Netherlands)

Author keywords

Draize Eye Test; In vitro assay; Validation

Indexed keywords

ARTICLE; DRAIZE EYE TEST; EXPOSURE; IN VITRO STUDY; NONHUMAN; SOLID; TECHNIQUE; VALIDATION PROCESS;

EID: 29144487939     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2005.06.030     Document Type: Note

References (6)

1. M. Balls, P.A. Botham, L.H. Bruner, and H. Spielmann The EC/HO international validation study on alternatives to the draize eye irritation test Toxicology in Vitro 9 6 1995 871 929
2. Commission of the European Communities, 1991. Collaborative study on the evaluation of alternative methods to the eye irritation test. EC Document XI/632/91, V/E/1/131/91.
3. CA, 2002. Competent Authority meeting of the European Communities. Agreement on the use of positive results obtained in non validated in vitro eye irritation tests.
4. F.E. Freeberg, G.A. Nixon, P.J. Reer, J.E. Weaver, R.D. Bruce, J.F. Griffith, and L.W. Sanders Human and rabbit eye responses to chemical insult Fundamental and Applied Toxicology 7 1986 626 634
5. J.F. Griffith, G.A. Nixon, R.D. Bruce, P.J. Reer, and E.A. Bannan Dose-response studies with chemical irritants in the albino rabbit eye as a basis for selecting optimum testing conditions for predicting hazard to the human eye Toxicology and Applied Pharmacology 55 1980 501 513
6. R. Roggeband, M. York, M. Pericoi, and W. Braun Eye irritation responses in rabbit and man after single applications of equal volumes of undiluted model liquid detergent products Food and Chemical Toxicology 38 8 2000 727 734