Extent of corneal injury as a biomarker for hazard assessment and the development of alternative models to the draize rabbit eye test

Cutaneous and Ocular Toxicology

Volumn 25, Issue 1, 2006, Pages 41-54

  Jester, James V ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alternatives to animal testing; Animal testing; Chemical irritants; Confocal; Microscopy; Ocular irritation; Rabbit; Replacement test

Indexed keywords

4 FLUOROANILINE; ACETIC ACID; ACETONE; ALCOHOL; ANIONIC SURFACTANT; BIOLOGICAL MARKER; BLEACHING AGENT; CATIONIC SURFACTANT; CYCLOHEXANOL; FORMALDEHYDE; HYDROGEN PEROXIDE; HYPOCHLORITE SODIUM; IRRITANT AGENT; NONIONIC SURFACTANT; PERBORATE SODIUM; SODIUM HYDROXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CORNEA ENDOTHELIUM; CORNEA EPITHELIUM; CORNEA INJURY; CORNEA STROMA; CORRELATION ANALYSIS; EYE IRRITATION; NONHUMAN; OUTCOMES RESEARCH; QUANTITATIVE ANALYSIS; RABBIT; RISK ASSESSMENT; SKIN TEST; STANDARD; TISSUE CULTURE; VALIDATION PROCESS;

ACUTE TOXICITY TESTS; ANIMAL TESTING ALTERNATIVES; ANIMALS; BIOLOGICAL MARKERS; CORNEA; EYE INJURIES; IRRITANTS; MICROSCOPY, CONFOCAL; RABBITS; RISK ASSESSMENT;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 33745070230     PISSN: 15569527     EISSN: 15569535     Source Type: Journal    
DOI: 10.1080/15569520500536626     Document Type: Article

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