In vitro ocular irritation toxicity study of some pesticides

Acta Veterinaria Hungarica

Volumn 48, Issue 2, 2000, Pages 221-228

  Budai, P ^a   Varnagy L ^a  

^a UNIVERSITY OF PANNONIA   (Hungary)

Author keywords

Chorioallantoic membrane; Draize rabbit eye test; Hen's egg test; HET CAM; In vitro; Ocular irritation; Pesticides

Indexed keywords

ANIMALIA; ORYCTOLAGUS CUNICULUS;

PESTICIDE;

ANIMAL; ANIMAL TESTING ALTERNATIVE; ARTICLE; BIOASSAY; CHICKEN; DRUG EFFECT; EVALUATION; EYE; IN VITRO STUDY; OOCYTE; RABBIT; ULTRASTRUCTURE;

ANIMAL TESTING ALTERNATIVES; ANIMALS; BIOLOGICAL ASSAY; CHICKENS; EYE; OVUM; PESTICIDES; RABBITS;

EID: 0034569990     PISSN: 02366290     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Atterwill, C. K. and Steele, C. E. (eds) (1987): In vitro Methods in Toxicology. Cambridge University Press, Cambridge.
2. Balls, M., Berg, N., Bruner, L., Curren, R. D., deSilva, O., Earl, L. K., Esdaile, D. J., Fentem, J. H., Liebsch, M., Ohno, Y., Prinsen, M. K., Spielmann, H. and Worth, A. P. (1999): Eye irritation testing: The way forward. ATLA 27, 53-77.
3. Draize, J. H., Woodard, G. and Calvery, H. O. (1944): Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J. Pharmacol. Exp. Ther. 82, 377-390.
4. Invittox Protocol Number 47. HET-CAM test 1990.
5. Leighton, J., Nassauer, J. and Tchao, R. (1985): The chick embryo in toxicology: an alternative to the rabbit eye. Fd. Chem. Toxic. 23, 293-298.
6. Luepke, N. P. and Kemper, F. H. (1986): The HET-CAM test: an alternative to the Draize eye test. Fd. Chem. Toxic. 24, 495-496.
7. Luepke, N. P. and Wallat, S. (1987): HET-CAM reproducibility studies. Altern. Meth. Toxicol. 5, 353-363.
8. OECD (1981): OECD Guidelines for Testing of Chemicals, Number 405. Paris, 1981.