메뉴 건너뛰기




Volumn 80, Issue 18, 2006, Pages 9159-9170

CD80 and CD86 control antiviral CD8+ T-cell function and immune surveillance of murine gammaherpesvirus 68

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD8 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; NEUTRALIZING ANTIBODY;

EID: 33748504774     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00422-06     Document Type: Article
Times cited : (52)

References (60)
  • 2
    • 0034176037 scopus 로고    scopus 로고
    • Role of CD40 ligand and CD28 in induction and maintenance of antiviral CD8+ effector T cell responses
    • Andreasen, S. O., J. E. Christensen, O. Marker, and A. R. Thomsen. 2000. Role of CD40 ligand and CD28 in induction and maintenance of antiviral CD8+ effector T cell responses. J. Immunol. 164:3689-3697.
    • (2000) J. Immunol. , vol.164 , pp. 3689-3697
    • Andreasen, S.O.1    Christensen, J.E.2    Marker, O.3    Thomsen, A.R.4
  • 3
    • 2342631978 scopus 로고    scopus 로고
    • Role of T cell costimulation in anti-viral immunity
    • Bertram, E. M., W. Dawicki, and T. H. Watts. 2004. Role of T cell costimulation in anti-viral immunity. Semin. Immunol. 16:185-196.
    • (2004) Semin. Immunol. , vol.16 , pp. 185-196
    • Bertram, E.M.1    Dawicki, W.2    Watts, T.H.3
  • 4
    • 0037090337 scopus 로고    scopus 로고
    • Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection
    • Bertram, E. M., P. Lau, and T. H. Watts. 2002. Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection. J. Immunol. 168:3777-3785.
    • (2002) J. Immunol. , vol.168 , pp. 3777-3785
    • Bertram, E.M.1    Lau, P.2    Watts, T.H.3
  • 7
    • 0036214017 scopus 로고    scopus 로고
    • The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
    • Carreno, B. M., and M. Collins. 2002. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu. Rev. Immunol. 20:29-53.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 29-53
    • Carreno, B.M.1    Collins, M.2
  • 9
    • 0033609007 scopus 로고    scopus 로고
    • CD4(+) T cell-mediated control of a gamma-herpesvirus in B cell-deficient mice is mediated by IFN-gamma
    • Christensen, J. P., R. D. Cardin, K. C. Branum, and P. C. Doherty. 1999. CD4(+) T cell-mediated control of a gamma-herpesvirus in B cell-deficient mice is mediated by IFN-gamma. Proc. Natl. Acad. Sci. USA 96:5135-5140.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5135-5140
    • Christensen, J.P.1    Cardin, R.D.2    Branum, K.C.3    Doherty, P.C.4
  • 10
    • 0032923882 scopus 로고    scopus 로고
    • + T-cell response to a persistent gammaherpesvirus
    • + T-cell response to a persistent gammaherpesvirus. J. Virol. 73:4279-4283.
    • (1999) J. Virol. , vol.73 , pp. 4279-4283
    • Christensen, J.P.1    Doherty, P.C.2
  • 11
    • 0030979780 scopus 로고    scopus 로고
    • Pathological changes in the spleens of gamma interferon receptor-deficient mice infected with murine gammaherpesvirus: A role for CD8 T cells
    • Dutia, B. M., C. J. Clarke, D. J. Allen, and A. A. Nash. 1997. Pathological changes in the spleens of gamma interferon receptor-deficient mice infected with murine gammaherpesvirus: a role for CD8 T cells. J. Virol. 71:4278-4283.
    • (1997) J. Virol. , vol.71 , pp. 4278-4283
    • Dutia, B.M.1    Clarke, C.J.2    Allen, D.J.3    Nash, A.A.4
  • 12
    • 0035163556 scopus 로고    scopus 로고
    • Role of CD28/CD80-86 and CD40/CD154 costimulatory interactions in host defense to primary herpes simplex virus infection
    • Edelmann, K. H., and C. B. Wilson. 2001. Role of CD28/CD80-86 and CD40/CD154 costimulatory interactions in host defense to primary herpes simplex virus infection. J. Virol. 75:612-621.
    • (2001) J. Virol. , vol.75 , pp. 612-621
    • Edelmann, K.H.1    Wilson, C.B.2
  • 13
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: New insights into its biological function and use in tumor immunotherapy
    • Egen, J. G., M. S. Kuhns, and J. P. Allison. 2002. CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat. Immunol. 3:611-618.
    • (2002) Nat. Immunol. , vol.3 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 14
    • 0027179405 scopus 로고
    • Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells
    • Ehtisham, S., N. P. Sunil-Chandra, and A. A. Nash. 1993. Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells. J. Virol. 67:5247-5252.
    • (1993) J. Virol. , vol.67 , pp. 5247-5252
    • Ehtisham, S.1    Sunil-Chandra, N.P.2    Nash, A.A.3
  • 15
    • 0034662270 scopus 로고    scopus 로고
    • Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages
    • Flano, E., S. M. Husain, J. T. Sample, D. L. Woodland, and M. A. Blackman. 2000. Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages. J. Immunol. 165:1074-1081.
    • (2000) J. Immunol. , vol.165 , pp. 1074-1081
    • Flano, E.1    Husain, S.M.2    Sample, J.T.3    Woodland, D.L.4    Blackman, M.A.5
  • 17
    • 0348013165 scopus 로고    scopus 로고
    • ORF73 of murine herpesvirus-68 is critical for the establishment and maintenance of latency
    • Fowler, P., S. Marques, J. P. Simas, and S. Efstathiou. 2003. ORF73 of murine herpesvirus-68 is critical for the establishment and maintenance of latency. J. Gen. Virol. 84:3405-3416.
    • (2003) J. Gen. Virol. , vol.84 , pp. 3405-3416
    • Fowler, P.1    Marques, S.2    Simas, J.P.3    Efstathiou, S.4
  • 21
    • 0242611000 scopus 로고    scopus 로고
    • CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool
    • Hendriks, J., Y. Xiao, and J. Borst. 2003. CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool. J. Exp. Med. 198:1369-1380.
    • (2003) J. Exp. Med. , vol.198 , pp. 1369-1380
    • Hendriks, J.1    Xiao, Y.2    Borst, J.3
  • 22
    • 22544437564 scopus 로고    scopus 로고
    • During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion
    • Hendriks, J., Y. Xiao, J. W. Rossen, K. F. van der Sluijs, K. Sugamura, N. Ishii, and J. Borst. 2005. During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion. J. Immunol. 175:1665-1676.
    • (2005) J. Immunol. , vol.175 , pp. 1665-1676
    • Hendriks, J.1    Xiao, Y.2    Rossen, J.W.3    Van Der Sluijs, K.F.4    Sugamura, K.5    Ishii, N.6    Borst, J.7
  • 23
    • 31144456952 scopus 로고    scopus 로고
    • Costimulation requirements for antiviral CD8+ T cells differ for acute and persistent phases of polyoma virus infection
    • Kemball, C. C., E. D. Lee, E. Szomolanyi-Tsuda, T. C. Pearson, C. P. Larsen, and A. E. Lukacher. 2006. Costimulation requirements for antiviral CD8+ T cells differ for acute and persistent phases of polyoma virus infection. J. Immunol. 176:1814-1824.
    • (2006) J. Immunol. , vol.176 , pp. 1814-1824
    • Kemball, C.C.1    Lee, E.D.2    Szomolanyi-Tsuda, E.3    Pearson, T.C.4    Larsen, C.P.5    Lukacher, A.E.6
  • 24
    • 0037090278 scopus 로고    scopus 로고
    • Antibody-mediated control of persistent gamma-herpesvirus infection
    • Kim, I. J., E. Flano, D. L. Woodland, and M. A. Blackman. 2002. Antibody-mediated control of persistent gamma-herpesvirus infection. J. Immunol. 168:3958-3964.
    • (2002) J. Immunol. , vol.168 , pp. 3958-3964
    • Kim, I.J.1    Flano, E.2    Woodland, D.L.3    Blackman, M.A.4
  • 25
    • 24944509220 scopus 로고    scopus 로고
    • T cells and viral persistence: Lessons from diverse infections
    • Klenerman, P., and A. Hill. 2005. T cells and viral persistence: lessons from diverse infections. Nat. Immunol. 6:873-879.
    • (2005) Nat. Immunol. , vol.6 , pp. 873-879
    • Klenerman, P.1    Hill, A.2
  • 26
    • 0036191093 scopus 로고    scopus 로고
    • -/- mice show defects in cellular and humoral immunity but are able to control infection with murine gammaherpesvirus 68
    • -/- mice show defects in cellular and humoral immunity but are able to control infection with murine gammaherpesvirus 68. J. Virol. 76:3049-3053.
    • (2002) J. Virol. , vol.76 , pp. 3049-3053
    • Lee, B.J.1    Reiter, S.K.2    Anderson, M.3    Sarawar, S.R.4
  • 27
    • 0033970952 scopus 로고    scopus 로고
    • Differential requirement for CD80 and CD80/CD86-dependent Costimulation in the lung immune response to an influenza virus infection
    • Lumsden, J. M., J. M. Roberts, N. L. Harris, R. J. Peach, and F. Ronchese. 2000. Differential requirement for CD80 and CD80/CD86-dependent Costimulation in the lung immune response to an influenza virus infection. J. Immunol. 164:79-85.
    • (2000) J. Immunol. , vol.164 , pp. 79-85
    • Lumsden, J.M.1    Roberts, J.M.2    Harris, N.L.3    Peach, R.J.4    Ronchese, F.5
  • 29
    • 0033988482 scopus 로고    scopus 로고
    • + cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus
    • + cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus. J. Virol. 74:203-208.
    • (2000) J. Virol. , vol.74 , pp. 203-208
    • McAdam, A.J.1    Farkash, E.A.2    Gewurz, B.E.3    Sharpe, A.H.4
  • 30
    • 0141856355 scopus 로고    scopus 로고
    • The gammaherpesvirus 68 latency-associated nuclear antigen homolog is critical for the establishment of splenic latency
    • Moorman, N. J., D. O. Wilier, and S. H. Speck. 2003. The gammaherpesvirus 68 latency-associated nuclear antigen homolog is critical for the establishment of splenic latency. J. Virol. 77:10295-10303.
    • (2003) J. Virol. , vol.77 , pp. 10295-10303
    • Moorman, N.J.1    Wilier, D.O.2    Speck, S.H.3
  • 31
    • 1642536435 scopus 로고    scopus 로고
    • Different functional capacities of latent and lytic antigen-specific CD8 T cells in murine gammaherpesvirus infection
    • Obar, J. J., S. G. Crist, D. C. Gondek, and E. J. Usherwood. 2004. Different functional capacities of latent and lytic antigen-specific CD8 T cells in murine gammaherpesvirus infection. J. Immunol. 172:1213-1219.
    • (2004) J. Immunol. , vol.172 , pp. 1213-1219
    • Obar, J.J.1    Crist, S.G.2    Gondek, D.C.3    Usherwood, E.J.4
  • 32
    • 4043125332 scopus 로고    scopus 로고
    • IL-15-independent proliferative renewal of memory CD8+ T cells in latent gammaherpesvirus infection
    • Obar, J. J., S. G. Crist, E. K. Leung, and E. J. Usherwood. 2004. IL-15-independent proliferative renewal of memory CD8+ T cells in latent gammaherpesvirus infection. J. Immunol. 173:2705-2714.
    • (2004) J. Immunol. , vol.173 , pp. 2705-2714
    • Obar, J.J.1    Crist, S.G.2    Leung, E.K.3    Usherwood, E.J.4
  • 33
    • 33748482479 scopus 로고    scopus 로고
    • Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection
    • 32a. Obar, J. J., S. Fuse, E. K. Leung, S. C. Bellfy, and E. J. Usherwood. 2006. Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection. J. Virol. 80:8303-8315.
    • (2006) J. Virol. , vol.80 , pp. 8303-8315
    • Obar, J.J.1    Fuse, S.2    Leung, E.K.3    Bellfy, S.C.4    Usherwood, E.J.5
  • 34
    • 0038655228 scopus 로고    scopus 로고
    • Cytokine control of memory T-cell development and survival
    • Schluns, K. S., and L. Lefrancois. 2003. Cytokine control of memory T-cell development and survival. Nat. Rev. Immunol. 3:269-279.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 269-279
    • Schluns, K.S.1    Lefrancois, L.2
  • 38
    • 0033041657 scopus 로고    scopus 로고
    • Immunological control of a murine gammaherpesvirus independent of CD8+ T cells
    • Stevenson, P. G., R. D. Cardin, J. P. Christensen, and P. C. Doherty. 1999. Immunological control of a murine gammaherpesvirus independent of CD8+ T cells. J. Gen. Virol. 80:477-483.
    • (1999) J. Gen. Virol. , vol.80 , pp. 477-483
    • Stevenson, P.G.1    Cardin, R.D.2    Christensen, J.P.3    Doherty, P.C.4
  • 39
    • 32944479900 scopus 로고    scopus 로고
    • Immune mechanisms in murine gammaherpesvirus-68 infection
    • Stevenson, P. G., and S. Efstathiou. 2005. Immune mechanisms in murine gammaherpesvirus-68 infection. Viral Immunol. 18:445-456.
    • (2005) Viral Immunol. , vol.18 , pp. 445-456
    • Stevenson, P.G.1    Efstathiou, S.2
  • 40
    • 0032526299 scopus 로고    scopus 로고
    • Lung epithelial cells are a major site of murine gammaherpesvirus persistence
    • Stewart, J. P., E. J. Usherwood, A. Ross, H. Dyson, and T. Nash. 1998. Lung epithelial cells are a major site of murine gammaherpesvirus persistence. J. Exp. Med. 187:1941-1951.
    • (1998) J. Exp. Med. , vol.187 , pp. 1941-1951
    • Stewart, J.P.1    Usherwood, E.J.2    Ross, A.3    Dyson, H.4    Nash, T.5
  • 41
    • 0026693757 scopus 로고
    • Virological and pathological features of mice infected with murine gammaherpesvirus 68
    • Sunil-Chandra, N. P., S. Efstathiou, J. Arno, and A. A. Nash. 1992. Virological and pathological features of mice infected with murine gammaherpesvirus 68. J. Gen. Virol. 73:2347-2356.
    • (1992) J. Gen. Virol. , vol.73 , pp. 2347-2356
    • Sunil-Chandra, N.P.1    Efstathiou, S.2    Arno, J.3    Nash, A.A.4
  • 42
    • 0027043122 scopus 로고
    • Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo
    • Sunil-Chandra, N. P., S. Efstathiou, and A. A. Nash. 1992. Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo. J. Gen. Virol. 73:3275-3279.
    • (1992) J. Gen. Virol. , vol.73 , pp. 3275-3279
    • Sunil-Chandra, N.P.1    Efstathiou, S.2    Nash, A.A.3
  • 44
    • 1642525948 scopus 로고    scopus 로고
    • Effect of chronic viral infection on epitope selection, cytokine production, and surface phenotype of CD8 T cells and the role of IFN-gamma receptor in immune regulation
    • Tewari, K., J. Sacha, X. Gao, and M. Suresh. 2004. Effect of chronic viral infection on epitope selection, cytokine production, and surface phenotype of CD8 T cells and the role of IFN-gamma receptor in immune regulation. J. Immunol. 172:1491-1500.
    • (2004) J. Immunol. , vol.172 , pp. 1491-1500
    • Tewari, K.1    Sacha, J.2    Gao, X.3    Suresh, M.4
  • 45
    • 0037320090 scopus 로고    scopus 로고
    • Mechanism of reduced T-cell effector functions and class-switched antibody responses to herpes simplex virus type 2 in the absence of B7 costimulation
    • Thebeau, L. G., and L. A. Morrison. 2003. Mechanism of reduced T-cell effector functions and class-switched antibody responses to herpes simplex virus type 2 in the absence of B7 costimulation. J. Virol. 77:2426-2435.
    • (2003) J. Virol. , vol.77 , pp. 2426-2435
    • Thebeau, L.G.1    Morrison, L.A.2
  • 46
    • 0036635343 scopus 로고    scopus 로고
    • Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus
    • Tibbetts, S. A., L. F. van Dyk, S. H. Speck, and H. W. Virgin IV. 2002. Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus. J. Virol. 76:7125-7132.
    • (2002) J. Virol. , vol.76 , pp. 7125-7132
    • Tibbetts, S.A.1    Van Dyk, L.F.2    Speck, S.H.3    Virgin IV, H.W.4
  • 47
    • 0036679631 scopus 로고    scopus 로고
    • A new approach to epitope confirmation by sampling effector/memory T cells migrating to the lung
    • Usherwood, E. J. 2002. A new approach to epitope confirmation by sampling effector/memory T cells migrating to the lung. J. Immunol. Methods 266:135-142.
    • (2002) J. Immunol. Methods , vol.266 , pp. 135-142
    • Usherwood, E.J.1
  • 49
    • 0037405936 scopus 로고    scopus 로고
    • Maintenance of gammaherpesvirus latency requires viral cyclin in the absence of B lymphocytes
    • van Dyk, L. F., H. W. Virgin IV, and S. H. Speck. 2003. Maintenance of gammaherpesvirus latency requires viral cyclin in the absence of B lymphocytes. J. Virol. 77:5118-5126.
    • (2003) J. Virol. , vol.77 , pp. 5118-5126
    • Van Dyk, L.F.1    Virgin IV, H.W.2    Speck, S.H.3
  • 50
    • 2942674463 scopus 로고    scopus 로고
    • Co-signaling molecules of the B7-CD28 family in positive and negative regulation of T lymphocyte responses
    • Wang, S., and L. Chen. 2004. Co-signaling molecules of the B7-CD28 family in positive and negative regulation of T lymphocyte responses. Microbes Infect. 6:759-766.
    • (2004) Microbes Infect. , vol.6 , pp. 759-766
    • Wang, S.1    Chen, L.2
  • 52
    • 17644389199 scopus 로고    scopus 로고
    • TNF/TNFR family members in costimulation of T cell responses
    • Watts, T. H. 2005. TNF/TNFR family members in costimulation of T cell responses. Annu. Rev. Immunol. 23:23-68.
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 23-68
    • Watts, T.H.1
  • 53
    • 0031464609 scopus 로고    scopus 로고
    • Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: A new model for virus-induced vascular disease
    • Week, K. E., A. J. Dal Canto, J. D. Gould, A. K. O'Guin, K. A. Roth, J. E. Saffitz, S. H. Speck, and H. W. Virgin. 1997. Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease. Nat. Med. 3:1346-1353.
    • (1997) Nat. Med. , vol.3 , pp. 1346-1353
    • Week, K.E.1    Dal Canto, A.J.2    Gould, J.D.3    O'Guin, A.K.4    Roth, K.A.5    Saffitz, J.E.6    Speck, S.H.7    Virgin, H.W.8
  • 54
    • 0032975256 scopus 로고    scopus 로고
    • Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells
    • Week, K. E., S. S. Kim, H. W. Virgin IV, and S. H. Speck. 1999. Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells. J. Virol. 73:3273-3283.
    • (1999) J. Virol. , vol.73 , pp. 3273-3283
    • Week, K.E.1    Kim, S.S.2    Virgin IV, H.W.3    Speck, S.H.4
  • 55
    • 2442684151 scopus 로고    scopus 로고
    • Memory CD8 T-cell differentiation during viral infection
    • Wherry, E. J., and R. Ahmed. 2004. Memory CD8 T-cell differentiation during viral infection. J. Virol. 78:5535-5545.
    • (2004) J. Virol. , vol.78 , pp. 5535-5545
    • Wherry, E.J.1    Ahmed, R.2
  • 56
    • 8644268831 scopus 로고    scopus 로고
    • Antigen-independent memory CD8 T cells do not develop during chronic viral infection
    • First published 25 October 2004; doi:10.1073/pnas.0407192101
    • Wherry, E. J., D. L. Barber, S. M. Kaech, J. N. Blattman, and R. Ahmed. 2004. Antigen-independent memory CD8 T cells do not develop during chronic viral infection. Proc. Natl. Acad. Sci. USA 101:16004-16009. (First published 25 October 2004; doi:10.1073/pnas.0407192101.)
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 16004-16009
    • Wherry, E.J.1    Barber, D.L.2    Kaech, S.M.3    Blattman, J.N.4    Ahmed, R.5
  • 57
    • 0030902622 scopus 로고    scopus 로고
    • CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion
    • Wu, Y., Y. Guo, A. Huang, P. Zheng, and Y. Liu. 1997. CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion. J. Exp. Med. 185:1327-1335.
    • (1997) J. Exp. Med. , vol.185 , pp. 1327-1335
    • Wu, Y.1    Guo, Y.2    Huang, A.3    Zheng, P.4    Liu, Y.5
  • 59
    • 0032568524 scopus 로고    scopus 로고
    • B7-CTLA4 interaction enhances both production of antitumor cytotoxic T lymphocytes and resistance to tumor-challenge
    • Zheng, P., Y. Wu, Y. Guo, C. Lee, and Y. Liu. 1998. B7-CTLA4 interaction enhances both production of antitumor cytotoxic T lymphocytes and resistance to tumor-challenge. Proc. Natl. Acad. Sci. USA 95:6284-6289.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6284-6289
    • Zheng, P.1    Wu, Y.2    Guo, Y.3    Lee, C.4    Liu, Y.5
  • 60
    • 0031047824 scopus 로고    scopus 로고
    • Antiviral immune responses in CTLA4 transgenic mice
    • Zimmermann, C., P. Seiler, P. Lane, and R. M. Zinkernagel. 1997. Antiviral immune responses in CTLA4 transgenic mice. J. Virol. 71:1802-1807.
    • (1997) J. Virol. , vol.71 , pp. 1802-1807
    • Zimmermann, C.1    Seiler, P.2    Lane, P.3    Zinkernagel, R.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.