Dementia and subnormal levels of vitamin B12: Effects of replacement therapy on dementia

Journal of Neurology

Volumn 243, Issue 7, 1996, Pages 522-529

  Teunisse, Saskia ^a   Bollen, Anna E ^a   Van Gool, Willem A ^a   Walstra, Gerard J M ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Dementia; Outcome assessment; Reversibility; Vitamin B12

Indexed keywords

CYANOCOBALAMIN;

AGED; ALZHEIMER DISEASE; ARTICLE; BEHAVIOR DISORDER; CAREGIVER; CLINICAL TRIAL; COGNITIVE DEFECT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYANOCOBALAMIN DEFICIENCY; DAILY LIFE ACTIVITY; DEMENTIA; FEMALE; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SUBSTITUTION THERAPY; TREATMENT OUTCOME;

AGED; ALZHEIMER DISEASE; DEMENTIA; FEMALE; HUMANS; MALE; PROGNOSIS; PSYCHIATRIC STATUS RATING SCALES; VITAMIN B 12;

EID: 0029939578     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00886874     Document Type: Article

References (43)

1. Adams RD, Kubik CS (1944) Subacute degeneration of the brain in pernicious anemia. N Engl J Med 231: 1-9
2. American Psychiatric Association (1987) Diagnostic and statistical manual of mental disorders - revised (3rd edn). American Psychiatric Association, Washington, DC
3. Baker HF, Thinds IS, Louria DB (1979) Vitamin profiles in elderly persons living at home or in nursing homes, versus profile in healthy young subjects. J Am Geriatr Soc 27: 444-450
4. Bayer AJ, Pathy MSJ, Twining C (1987) The memory clinic, a new approach to the detection of early dementia. Drugs 33 [Suppl 2]: 84-89
5. Burns A, Jacoby R, Levy R (1991) Progression of cognitive impairment in Alzheimer's Disease. J Am Geriatr Soc 39: 39-45
6. Derix MMA, Teunisse S, Hijdra A, Wens L, Hofstede AB, Walstra GJM, Weinstein HC, Van Gool WA (1992) Camdex-N, the Dutch version of the Cambridge Examination for Mental Disorders of the Elderly. Swets & Zeitlinger, Lisse
7. Diesfeldt HFA (1981) The interpretation of changes in BOP scores on longitudinal study of individual patients (in Dutch). Gerontologie 12: 212-217
8. 12 hypovitaminosis in mental diseases. Acta Med Scand 177: 689-699
9. 12 levels in the aged. Acta Med Scand 200: 309-314
10. 12 deficiency. Am J Psychiatry 140: 218-221
11. Folstein MF, Folstein SE, McHugh PR (1975) "Mini Mental State": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12: 189-198
12. Fox JH, Topel JL, Huckman MS (1975) Dementia in the elderly - a search for treatable illnesses. J Gerontol 30: 557-564
13. 12 status in a healthy elderly population. J Am Geriatr Soc 32: 719-726
14. Gross JS, Weintraub NT, Neufeld RR, Libow LS (1986) Pernicious anemia in the demented patient without anemia or macrocytosis. J Am Geriatr Soc 34: 612-614
15. Haley WE, Pardo KM (1989) Relationship of severity of dementia to caregiving stressors. Psychol Aging 4: 389-392
16. Healton EB, Savage DG, Brust JCM, Garrett TJ, Lindenbaum J (1991) Neurologic aspects of cobalamin deficiency. Medicine 70: 229-245
17. 12 deficiency? J Am Geriatr Soc 36: 1105-1112
18. 12 deficiency. B M J 2: 1394-1398
19. 12 and folate concentrations in mental patients. Br J Psychiatry 113: 1291-1295
20. 12 deficiency in psychiatric patients. Acta Psychiatr Scand [Suppl] 221: 133-142
21. 12 (cobalamin) deficiency in the elderly (in Dutch). Ned Tijdschr Geneeskd 134: 652-656
22. Kassirer JP, Kopelman RI (1988) Searching for a pony. Hosp Pract 23: 17-19
23. Larson EB, Reifler BV, Sumi SM, Canfield CG, Chinn NM (1985) Diagnostic evaluation of 200 elderly outpatients with suspected dementia. J Gerontol 40: 536-543
24. Larson EB, Reifler BV, Sumi SM, Canfield CG, Chinn NM (1986) Diagnostic tests in the evaluation of dementia: a prospective study of 200 elderly outpatients. Arch Intern Med 146: 1917-1922
25. Lindeboom J, Ter Horst R, Hooyer C, Dinkgreve M, Jonker C (1993) Some psychometric properties of the CAMCOG. Psychol Med 23: 213-219
26. Lindenbaum J, Healton EB, Savage DG, Brust JCM, Garrett TJ, Podell ER, Marcell PD, Stabler SP, Allen RH (1988) Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med 318: 1720-1728
27. Lord FM, Novick MR (1974) Statistical theories of mental test scores. Addison-Wesley, Reading, Mass
28. Martin DC, Francis J, Protetch J, Huff FJ (1992) Time dependency of cognitive recovery with cobalamin replacement: report of a pilot study. J Am Geriatr Soc 40: 168-172
29. McKhann G, Drachmann D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's Disease: report of the NINCDSADRDA Work Group under the auspices of Department of Health and Human Service Task Force on Alzheimer's Disease. Neurology 34: 939-944
30. 12 therapy: a longitudinal neuropsychological assessment. Neurology 44: 1764-1765
31. Morris JC, Edland S, Clark C, Galasko D, Koss E, Mohs R, van Belle G, Fillenbaum G, Heyman A (1993) The consortium to establish a registry for Alzheimer's Disease (CERAD). IV. Rates of cognitive change in the longitudinal assessment of probable Alzheimer's disease. Neurology 43: 2457-2465
32. 12 deficiency. J Am Geriatr Soc 41: 192-193
33. Renvoize EB, Gaskell RK, Klar HM (1985) Results of investigations in 150 demented patients consecutively admitted to a psychiatric hospital. Br J Psychiatry 147: 204-205
34. Roth M, Tym E, Mountjoy CQ, Huppert FA, Hendrie H, Verma S, Goddard R (1986) Camdex: a standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia. Br J Psychiatry 149: 698-709
35. 12 deficiency in an elderly psychiatric population. Br J Psychiatry 113: 241-251
36. Stabler SP, Allen RH, Savage DG, Lindenbaum J (1990) Clinical spectrum and diagnosis of cobalamin deficiency. Blood 76: 871-881
37. 12 with normal blood and marrow. Q J Med 135: 303-317
38. Teri L, Truax P, Logsdon R, Uomoto J, Zarit S, Vitaliano PP (1992) Assessment of behavioral problems in dementia: the Revised Memory and Behavioral Problems Checklist. Psychol Aging 7: 622-631
39. Teunisse S (1995) Activities of daily living scales in dementia: their development and future. In: Levy R. Howard R (eds). Developments in dementia and functional disorders in the elderly. Wriahtson, Petersfield, pp 85-95
40. Teunisse S, Derix MMA (1991) Measurement of functioning in daily life of dementia patients living at home: development of a questionnaire (in Dutch). Tijdschr Gerontol Geriatr 22: 53-59
41. Teunisse S, Derix MMA, Van Crevel H (1991) Assessing the severity of dementia: patient and caregiver. Arch Neurol 48: 274-277
42. Van Belle G, Uhlmann RF, Hughes JP, Larson EB (1990) Reliability of estimates of changes in mental status test performance in senile dementia of the Alzheimer type. J Clin Epidemiol 43: 589-595
43. Vernooij-Dassen M (1993) Dementia and home care; determinants of the sense of competence of primary care givers and the effects of professionally guided caregivers support (in Dutch) (dissertation). Swets & Zeitlinger, Lisse