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Volumn 22, Issue 3, 2006, Pages 469-478

Involvement of NF-κB in the response of embryonic cells to Methotrexate

Author keywords

Apoptosis; Bax; I B ; MEFs; MTX; NF B; Teratogens

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHOTREXATE; PROTEIN BAX; SYNAPTOTAGMIN; ANTINEOPLASTIC ANTIMETABOLITE; APOPTOSIS REGULATORY PROTEIN; BAX PROTEIN, MOUSE; I KAPPA B; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; RELA PROTEIN, MOUSE; TRANSCRIPTION FACTOR RELA;

EID: 33748423065     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2005.12.010     Document Type: Article
Times cited : (4)

References (54)
  • 1
    • 0033595892 scopus 로고    scopus 로고
    • The Rel/NF-kB signal transduction pathway: introduction
    • Gilmore T.D. The Rel/NF-kB signal transduction pathway: introduction. Oncogene 18 (1999) 6842-6844
    • (1999) Oncogene , vol.18 , pp. 6842-6844
    • Gilmore, T.D.1
  • 2
    • 0029666276 scopus 로고    scopus 로고
    • Interleukin-1β and glutamate activate Rel/NF-kB binding site from the regulatory region of the amyloid precursor protein gene in primary neuronal cultures
    • Grilli M., Goffi F., Memo M., and Spano P.F. Interleukin-1β and glutamate activate Rel/NF-kB binding site from the regulatory region of the amyloid precursor protein gene in primary neuronal cultures. J Biol Chem 271 (1996) 15002-15007
    • (1996) J Biol Chem , vol.271 , pp. 15002-15007
    • Grilli, M.1    Goffi, F.2    Memo, M.3    Spano, P.F.4
  • 3
    • 0029814063 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB/Rel induces apoptosis of murine B Cells
    • Wu M., Lee H., Bellas R.E., Schauer S.L., Arsura M., Katz D., et al. Inhibition of NF-kappaB/Rel induces apoptosis of murine B Cells. EMBO J 15 (1996) 4682-4690
    • (1996) EMBO J , vol.15 , pp. 4682-4690
    • Wu, M.1    Lee, H.2    Bellas, R.E.3    Schauer, S.L.4    Arsura, M.5    Katz, D.6
  • 4
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson M.D., Weil M., and Raff M.C. Programmed cell death in animal development. Cell 88 (1997) 347354
    • (1997) Cell , vol.88 , pp. 347354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 5
    • 0141922375 scopus 로고
    • Principles of abnormal development: past, present and future
    • Kimmel C.A., and Beulke-Sam J. (Eds), Raven Press, New York
    • Sadler T.W., and Hunter E.S. Principles of abnormal development: past, present and future. In: Kimmel C.A., and Beulke-Sam J. (Eds). Developmental toxicology (1994), Raven Press, New York 5363
    • (1994) Developmental toxicology , pp. 5363
    • Sadler, T.W.1    Hunter, E.S.2
  • 6
    • 0000655536 scopus 로고    scopus 로고
    • Cell death
    • Kavlock R.J., and Daston G.P. (Eds), Springer-Verlag, Berlin, Heidelberg
    • Knudsen T.V. Cell death. In: Kavlock R.J., and Daston G.P. (Eds). Drug toxicity in embryonic development I (1997), Springer-Verlag, Berlin, Heidelberg 211-244
    • (1997) Drug toxicity in embryonic development I , pp. 211-244
    • Knudsen, T.V.1
  • 7
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappaB
    • Beg A.A., Sha W.C., Bronson R.T., Ghosh S., and Baltimore D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappaB. Nature 376 (1995) 167-170
    • (1995) Nature , vol.376 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5
  • 8
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-κB in preventing TNF-α induced cell death
    • Beg A.A., and Baltimore D. An essential role for NF-κB in preventing TNF-α induced cell death. Science 274 (1996) 782-784
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 10
    • 0032852954 scopus 로고    scopus 로고
    • Maternal immunopotentiation affects the teratogenic response to hyperthermia
    • Yitzhakie D., Torchinsky A., Savion S., and Toder V. Maternal immunopotentiation affects the teratogenic response to hyperthermia. J Reprod Immunol 45 (1999) 49-66
    • (1999) J Reprod Immunol , vol.45 , pp. 49-66
    • Yitzhakie, D.1    Torchinsky, A.2    Savion, S.3    Toder, V.4
  • 11
    • 0033900805 scopus 로고    scopus 로고
    • Comparison of in vitro and in vivo developmental toxicity and pharmacokinetics of phenytoin in the rat
    • Beekhuijzen M.E., Verhoef A., Klaassen R., Rompelberg C.J., and Piersma A.H. Comparison of in vitro and in vivo developmental toxicity and pharmacokinetics of phenytoin in the rat. Pharmacol Toxicol 87 (2000) 96-102
    • (2000) Pharmacol Toxicol , vol.87 , pp. 96-102
    • Beekhuijzen, M.E.1    Verhoef, A.2    Klaassen, R.3    Rompelberg, C.J.4    Piersma, A.H.5
  • 12
    • 0037253339 scopus 로고    scopus 로고
    • Retinoic acid decreases the viability of mouse blastocysts in vitro
    • Huang F.J., Shen C.C., Chang S.Y., Wu T.C., and Hsuuw Y.D. Retinoic acid decreases the viability of mouse blastocysts in vitro. Hum Reprod 18 (2003) 130-136
    • (2003) Hum Reprod , vol.18 , pp. 130-136
    • Huang, F.J.1    Shen, C.C.2    Chang, S.Y.3    Wu, T.C.4    Hsuuw, Y.D.5
  • 13
    • 0037398980 scopus 로고    scopus 로고
    • Increased TNF-α expression in cultured mouse embryos exposed to teratogenic concentrations of glucose
    • Torchinsky A., Brokhman I., Shepshelovich J., Orenstein H., Savion S., Zaslavsky Z., et al. Increased TNF-α expression in cultured mouse embryos exposed to teratogenic concentrations of glucose. Reproduction 125 (2003) 527-534
    • (2003) Reproduction , vol.125 , pp. 527-534
    • Torchinsky, A.1    Brokhman, I.2    Shepshelovich, J.3    Orenstein, H.4    Savion, S.5    Zaslavsky, Z.6
  • 15
    • 0036195728 scopus 로고    scopus 로고
    • In utero ethanol suppresses cerebellar activator protein-1 and nuclear factor-kappa B transcriptional activation in a rat fetal alcohol syndrome model
    • Acquaah-Mensah G.K., Kehrer J.P., and Leslie S.W. In utero ethanol suppresses cerebellar activator protein-1 and nuclear factor-kappa B transcriptional activation in a rat fetal alcohol syndrome model. J Pharmacol Exp Ther 301 (2002) 277-283
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 277-283
    • Acquaah-Mensah, G.K.1    Kehrer, J.P.2    Leslie, S.W.3
  • 16
    • 0036787835 scopus 로고    scopus 로고
    • Misregulation of gene expression in the redox-sensitive NF-kappab-dependent limb outgrowth pathway by thalidomide
    • Hansen J.M., Gong S.G., Philbert M., and Harris C. Misregulation of gene expression in the redox-sensitive NF-kappab-dependent limb outgrowth pathway by thalidomide. Dev Dyn 225 (2002) 186-194
    • (2002) Dev Dyn , vol.225 , pp. 186-194
    • Hansen, J.M.1    Gong, S.G.2    Philbert, M.3    Harris, C.4
  • 17
    • 0242407708 scopus 로고    scopus 로고
    • Activation of NF-kappaB by Toxoplasma gondii correlates with increased expression of antiapoptotic genes and localization of phosphorylated IkappaB to the parasitophorous vacuole membrane
    • Molestina R.E., Payne T.M., Coppens I., and Sinai A.P. Activation of NF-kappaB by Toxoplasma gondii correlates with increased expression of antiapoptotic genes and localization of phosphorylated IkappaB to the parasitophorous vacuole membrane. J Cell Sci 116 (2003) 4359-4371
    • (2003) J Cell Sci , vol.116 , pp. 4359-4371
    • Molestina, R.E.1    Payne, T.M.2    Coppens, I.3    Sinai, A.P.4
  • 18
    • 0028315470 scopus 로고
    • The methotrexate story: a paradigm for development of cancer chemoterapeutic agents
    • Huennekens F.M. The methotrexate story: a paradigm for development of cancer chemoterapeutic agents. Adv Enzyme Regul 34 (1994) 397-419
    • (1994) Adv Enzyme Regul , vol.34 , pp. 397-419
    • Huennekens, F.M.1
  • 19
    • 0032736894 scopus 로고    scopus 로고
    • The effect of methotrexate on pregnancy, fertility and lactation
    • Lloyd M.E., Carr M., McElhatton P., Hall G.M., and Hughes R.A. The effect of methotrexate on pregnancy, fertility and lactation. QJM 92 (1999) 551-563
    • (1999) QJM , vol.92 , pp. 551-563
    • Lloyd, M.E.1    Carr, M.2    McElhatton, P.3    Hall, G.M.4    Hughes, R.A.5
  • 21
    • 0032199722 scopus 로고    scopus 로고
    • Methotrexate-resistant form of dihydrofolate reductase protects transgenic murine embryos from teratogenic effect of methotrexate
    • Sutton C., McIvor R.S., Vagt M., Doggett B., and Kapur R.P. Methotrexate-resistant form of dihydrofolate reductase protects transgenic murine embryos from teratogenic effect of methotrexate. Pediatr Dev Pathol 1 (1998) 503-512
    • (1998) Pediatr Dev Pathol , vol.1 , pp. 503-512
    • Sutton, C.1    McIvor, R.S.2    Vagt, M.3    Doggett, B.4    Kapur, R.P.5
  • 22
    • 0017360453 scopus 로고
    • Embryotoxicity of the folate antagonist methotrexate in rats and rabbits
    • Jordan R.L., Wilson J.G., and Schumacher H.J. Embryotoxicity of the folate antagonist methotrexate in rats and rabbits. Teratology 15 (1977) 73-80
    • (1977) Teratology , vol.15 , pp. 73-80
    • Jordan, R.L.1    Wilson, J.G.2    Schumacher, H.J.3
  • 24
    • 0031897632 scopus 로고    scopus 로고
    • NF-κB and rel proteins: evolutionarily conserved mediators of immune responses
    • Sankar G., Michael J.M., and Kopp B.E. NF-κB and rel proteins: evolutionarily conserved mediators of immune responses. Ann Rev Immunol 16 (1998) 225-260
    • (1998) Ann Rev Immunol , vol.16 , pp. 225-260
    • Sankar, G.1    Michael, J.M.2    Kopp, B.E.3
  • 26
    • 0030787585 scopus 로고    scopus 로고
    • Ubiquitous heritable damage in cell populations that survive treatment with methotrexate
    • Chow M., and Rubin H. Ubiquitous heritable damage in cell populations that survive treatment with methotrexate. Proc Natl Acad Sci USA 94 (1997) 8773-8778
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8773-8778
    • Chow, M.1    Rubin, H.2
  • 28
    • 0035847012 scopus 로고    scopus 로고
    • The Rela (p65) subunit of NF-kappaB is essential for inhibiting double-stranded RNA-induced cytotoxicity
    • Li M., Shillinglaw W., Henzel W.J., and Beg A.A. The Rela (p65) subunit of NF-kappaB is essential for inhibiting double-stranded RNA-induced cytotoxicity. J Biol Chem 276 (2001) 1185-1194
    • (2001) J Biol Chem , vol.276 , pp. 1185-1194
    • Li, M.1    Shillinglaw, W.2    Henzel, W.J.3    Beg, A.A.4
  • 29
    • 0033551787 scopus 로고    scopus 로고
    • Heat shock inhibits radiation-induced activation of NF-kappaB via inhibition of I-kappaB kinase
    • Curry H.A., Clemens R.A., Shah S., Bradbury C.M., Botero A., Goswami P., et al. Heat shock inhibits radiation-induced activation of NF-kappaB via inhibition of I-kappaB kinase. J Biol Chem 274 (1999) 23061-23067
    • (1999) J Biol Chem , vol.274 , pp. 23061-23067
    • Curry, H.A.1    Clemens, R.A.2    Shah, S.3    Bradbury, C.M.4    Botero, A.5    Goswami, P.6
  • 30
    • 0036024969 scopus 로고    scopus 로고
    • An IkB-α mutant inhibits cytokine gene expression and proliferation in human vascular smooth muscle cells
    • Wang Z., Castresana M.R., Detmer K., and Newman W.H. An IkB-α mutant inhibits cytokine gene expression and proliferation in human vascular smooth muscle cells. J Surg Res 102 (2002) 198-206
    • (2002) J Surg Res , vol.102 , pp. 198-206
    • Wang, Z.1    Castresana, M.R.2    Detmer, K.3    Newman, W.H.4
  • 31
    • 0031811423 scopus 로고    scopus 로고
    • Methotrexate induces apoptotic cell death in human keratinocytes
    • Heenen M., Laporte M., Noel J.C., and de Graef C. Methotrexate induces apoptotic cell death in human keratinocytes. Arch Dermatol Res 290 (1998) 240-245
    • (1998) Arch Dermatol Res , vol.290 , pp. 240-245
    • Heenen, M.1    Laporte, M.2    Noel, J.C.3    de Graef, C.4
  • 32
    • 0037305821 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappaB and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
    • Bharti A.C., Donato N., Singh S., and Aggarwal B.B. Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappaB and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood 101 (2003) 1053-1062
    • (2003) Blood , vol.101 , pp. 1053-1062
    • Bharti, A.C.1    Donato, N.2    Singh, S.3    Aggarwal, B.B.4
  • 34
    • 0038326642 scopus 로고    scopus 로고
    • Differential control of cell cycle, proliferation, and survival of primary T lymphocyes by purine and pyrimidine nucleotides
    • Quemeneur L., Gerald L.M., Flacher M., French M., Revillard J.P., and Genestier L. Differential control of cell cycle, proliferation, and survival of primary T lymphocyes by purine and pyrimidine nucleotides. J Immunol 170 (2003) 4986-4995
    • (2003) J Immunol , vol.170 , pp. 4986-4995
    • Quemeneur, L.1    Gerald, L.M.2    Flacher, M.3    French, M.4    Revillard, J.P.5    Genestier, L.6
  • 35
    • 0029121917 scopus 로고
    • Antisense oligonucleotides to the p65 subunit of NF-kB inhibit human vascular smooth muscle cell adherence and proliferation and prevent neointima formation in rat carotid arteries
    • Autieri M.V., Yue T.L., Ferstein G.Z., and Ohlstein E. Antisense oligonucleotides to the p65 subunit of NF-kB inhibit human vascular smooth muscle cell adherence and proliferation and prevent neointima formation in rat carotid arteries. Biochem Biophys Res Commun 213 (1995) 827-836
    • (1995) Biochem Biophys Res Commun , vol.213 , pp. 827-836
    • Autieri, M.V.1    Yue, T.L.2    Ferstein, G.Z.3    Ohlstein, E.4
  • 36
    • 0033006981 scopus 로고    scopus 로고
    • Soy-derived antiapoptotic fractions protect gastrointestinal epithelium from damage caused by methotrexate treatment in the rat
    • Logvinova A.V., Foehr M.W., Pemberton P.A., Khazalpour K.M., Funk-Archuleta M.A., Bathurst I.C., et al. Soy-derived antiapoptotic fractions protect gastrointestinal epithelium from damage caused by methotrexate treatment in the rat. Nutr Cancer 33 (1999) 33-39
    • (1999) Nutr Cancer , vol.33 , pp. 33-39
    • Logvinova, A.V.1    Foehr, M.W.2    Pemberton, P.A.3    Khazalpour, K.M.4    Funk-Archuleta, M.A.5    Bathurst, I.C.6
  • 38
    • 0036094174 scopus 로고    scopus 로고
    • Induction of apoptosis and modulation of activation and effector function in T cells by immunosuppressive drugs
    • Strauss G., Osen W., and Debatkin K.M. Induction of apoptosis and modulation of activation and effector function in T cells by immunosuppressive drugs. Clin Exp Immunol 128 (2002) 255-266
    • (2002) Clin Exp Immunol , vol.128 , pp. 255-266
    • Strauss, G.1    Osen, W.2    Debatkin, K.M.3
  • 39
    • 0842334493 scopus 로고    scopus 로고
    • Inhibition of nuclear factor-kB cascade potentiates the effect of a combination treatment of anaplastic thyroid cancer cells
    • Starenki D., Namba H., Saenko V., Ohtsuri A., and Yamashita S. Inhibition of nuclear factor-kB cascade potentiates the effect of a combination treatment of anaplastic thyroid cancer cells. J Clin Endocrinol Metab 89 (2004) 410-418
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 410-418
    • Starenki, D.1    Namba, H.2    Saenko, V.3    Ohtsuri, A.4    Yamashita, S.5
  • 40
    • 0036716281 scopus 로고    scopus 로고
    • The bcl-2 family: regulators of the cellular life-or-death switch
    • Cory S., and Adams J.M. The bcl-2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2 (2002) 647-656
    • (2002) Nat Rev Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 41
    • 0036023349 scopus 로고    scopus 로고
    • Apoptosis in normal rat embryo tissues during early organogenesis: the possible involvement of Bax and bcl-2
    • Sun F., Akazawa S., Sugahara K., Kamihira S., Kawasaki E., and Eguchi K. Apoptosis in normal rat embryo tissues during early organogenesis: the possible involvement of Bax and bcl-2. Arch Histol Cytol 65 (2002) 145-157
    • (2002) Arch Histol Cytol , vol.65 , pp. 145-157
    • Sun, F.1    Akazawa, S.2    Sugahara, K.3    Kamihira, S.4    Kawasaki, E.5    Eguchi, K.6
  • 42
    • 33748423098 scopus 로고    scopus 로고
    • Mammon K, Savion S, Keshet R, Orenstein H, Fein A, Torchinsky A, et al. Expression of apoptosis-associated molecules in the fetoplacental unit of teratogen-treated mice. Reproduction, submitted for publication.
  • 43
    • 0035012888 scopus 로고    scopus 로고
    • Nitric oxide as a regulator in preimplantation embryo development and apoptosis
    • Chen H.W., Jiang W.S., and Tzeng C.R. Nitric oxide as a regulator in preimplantation embryo development and apoptosis. Fertil Steril 75 (2001) 1163-1171
    • (2001) Fertil Steril , vol.75 , pp. 1163-1171
    • Chen, H.W.1    Jiang, W.S.2    Tzeng, C.R.3
  • 44
    • 0242363204 scopus 로고    scopus 로고
    • Cadmium-induced changes in apoptotic gene expression levels and DNA damage in mouse embryos are blocked by zinc
    • Fernandez E.L., Gustafson A.L., Andersson M., Hellman B., and Dencker L. Cadmium-induced changes in apoptotic gene expression levels and DNA damage in mouse embryos are blocked by zinc. Toxicol Sci 76 (2003) 162-170
    • (2003) Toxicol Sci , vol.76 , pp. 162-170
    • Fernandez, E.L.1    Gustafson, A.L.2    Andersson, M.3    Hellman, B.4    Dencker, L.5
  • 45
    • 0141836884 scopus 로고    scopus 로고
    • Increase in bcl-2 phosphorylation and reduced levels of BH3-only bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brain
    • Korhonen L., Belluardo N., Mudo G., and Lindholm D. Increase in bcl-2 phosphorylation and reduced levels of BH3-only bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brain. Eur J Neurosci 18 (2003) 1121-1134
    • (2003) Eur J Neurosci , vol.18 , pp. 1121-1134
    • Korhonen, L.1    Belluardo, N.2    Mudo, G.3    Lindholm, D.4
  • 46
    • 0028179224 scopus 로고
    • NF-kB and IkBα: an inducible regulatory system in endothelial activation
    • Read M., Whitley M.Z., Williams A.J., and Collins T. NF-kB and IkBα: an inducible regulatory system in endothelial activation. J Exp Med 179 (1994) 503-512
    • (1994) J Exp Med , vol.179 , pp. 503-512
    • Read, M.1    Whitley, M.Z.2    Williams, A.J.3    Collins, T.4
  • 47
    • 1242352473 scopus 로고    scopus 로고
    • Role of curcumin and the inhibitor of NF-kB in the onset of chemotherapy-induced mucosal barrier injury
    • van't Land B., Blijlevens N.M.A., Marteihn J., Timal S., Donnelly J.P., de Witte T.J.M., et al. Role of curcumin and the inhibitor of NF-kB in the onset of chemotherapy-induced mucosal barrier injury. Leukemia 18 (2004) 276-284
    • (2004) Leukemia , vol.18 , pp. 276-284
    • van't Land, B.1    Blijlevens, N.M.A.2    Marteihn, J.3    Timal, S.4    Donnelly, J.P.5    de Witte, T.J.M.6
  • 48
    • 0027453548 scopus 로고
    • Promoter analysis of the gene encoding the IkBα/mad3 inhibitor of NF-kB: positive regulation by members of the rel/NF-kB family
    • LeBail O., Schmidtullrich R., and Israël A. Promoter analysis of the gene encoding the IkBα/mad3 inhibitor of NF-kB: positive regulation by members of the rel/NF-kB family. EMBO J 12 (1993) 5043-5049
    • (1993) EMBO J , vol.12 , pp. 5043-5049
    • LeBail, O.1    Schmidtullrich, R.2    Israël, A.3
  • 49
    • 0027168447 scopus 로고
    • NF-kB controls expression of inhibitor IkBα: evidence for an inducible autoregulatory pathway
    • Sun S.C., Ganchi P.A., Ballard D.W., and Greene W.C. NF-kB controls expression of inhibitor IkBα: evidence for an inducible autoregulatory pathway. Science 259 (1993) 1912-1915
    • (1993) Science , vol.259 , pp. 1912-1915
    • Sun, S.C.1    Ganchi, P.A.2    Ballard, D.W.3    Greene, W.C.4
  • 51
    • 0028170124 scopus 로고
    • Three NF-kB sites in the IkB-α promoter are required for induction of gene expression by TNF-α
    • Ito C., Kazantsev A.G., and Baldwin Jr. A.S. Three NF-kB sites in the IkB-α promoter are required for induction of gene expression by TNF-α. Nucleic Acids Res 22 (1994) 3787-3792
    • (1994) Nucleic Acids Res , vol.22 , pp. 3787-3792
    • Ito, C.1    Kazantsev, A.G.2    Baldwin Jr., A.S.3
  • 52
    • 0031057644 scopus 로고    scopus 로고
    • Nuclear localization of I kappa B alpha promotes qctive transport of NF kappa B from the nucleus to the cytoplasm
    • Arenzana-Seisdedos F., Turpin P., Rodriguez M., Thomas D., Hay R.T., Virelizier J.L., et al. Nuclear localization of I kappa B alpha promotes qctive transport of NF kappa B from the nucleus to the cytoplasm. J Cell Sci 110 (1997) 369-378
    • (1997) J Cell Sci , vol.110 , pp. 369-378
    • Arenzana-Seisdedos, F.1    Turpin, P.2    Rodriguez, M.3    Thomas, D.4    Hay, R.T.5    Virelizier, J.L.6
  • 53
    • 0026783210 scopus 로고
    • IkappaB interacts with the nuclear localization sequences of the subunits of NF-kappaB: a mechanism for cytoplasmatic retention
    • Beg A.A., Ruben S.M., Scheinman R.I., Haskill S., Rosen C.A., and Baldwin Jr. A.S. IkappaB interacts with the nuclear localization sequences of the subunits of NF-kappaB: a mechanism for cytoplasmatic retention. Genes Dev 6 (1992) 1899-1913
    • (1992) Genes Dev , vol.6 , pp. 1899-1913
    • Beg, A.A.1    Ruben, S.M.2    Scheinman, R.I.3    Haskill, S.4    Rosen, C.A.5    Baldwin Jr., A.S.6
  • 54
    • 0142105387 scopus 로고    scopus 로고
    • Genetic analysis of NF-kappaB/Rel transcription factors defines functional specificities
    • Hoffmann A., Leung T.H., and Baltimore D. Genetic analysis of NF-kappaB/Rel transcription factors defines functional specificities. EMBO J 22 (2003) 5530-5539
    • (2003) EMBO J , vol.22 , pp. 5530-5539
    • Hoffmann, A.1    Leung, T.H.2    Baltimore, D.3


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