Differences in innate immune responses upon stimulation with gram-positive and gram-negative bacteria

Journal of Periodontal Research

Volumn 41, Issue 5, 2006, Pages 447-454

  Tietze, Konrad ^a   Dalpke, Alexander ^b   Morath, Sigfried ^c   Mutters, Reinier ^a   Heeg, Klaus ^b   Nonnenmacher, Claudia ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c JOINT RESEARCH CENTRE   (Italy)

Author keywords

Cytokines; Gram negative; Gram positive; Porphyromonas gingivalis lipopolysaccharide; Toll like receptors

Indexed keywords

BACTERIAL ANTIGEN; INTERLEUKIN 8; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BIOSYNTHESIS; BLOOD; C3H MOUSE; CELL CULTURE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; MICROBIOLOGY; MOUSE; PERIODONTITIS; PERITONEUM MACROPHAGE;

ANIMALS; ANTIGENS, BACTERIAL; CELLS, CULTURED; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; IMMUNITY, INNATE; IMMUNITY, NATURAL; INTERLEUKIN-8; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C3H; PERIODONTITIS; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33748368900     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2006.00890.x     Document Type: Article

References (33)

1. Bruce JP, Boches SK, Galvin JL, et al. Bacterial diversity in human subgingival plaque. J Bacteriol 2001; 183: 3770-3783.
2. Socransky SS, Haffajee AD, Ximenez-Fyvie LA, Feres M, Mager D. Ecological considerations in the treatment of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis periodontal infections. Periodontol 2000 1999; 20: 341-362.
3. Medzhitov R Jr, Janeway CA. Innate immunity. N Engl J Med 2000; 343: 338-344.
4. De Kimpe SJ, Kengatharan M, Thiemermann C, Vane JR. The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure. Proc Natl Acad Sci USA 1995; 92: 10359-10363.
5. Bjork L, Andersson J, Ceska M, Andersson U. Endotoxin and Staphylococcus aureus enterotoxin A induce different patterns of cytokines. Cytokine 1992; 4: 513-519.
6. Muller-Alouf H, Alouf JE, Gerlach D, Ozegowski JH, Fitting C, Cavaillon JM. Comparative study of cytokine release by human peripheral blood mononuclear cells stimulated with Streptococcus pyogenes superantigenic erythrogenic toxins, heat-killed streptococci, and lipopolysaccharide. Infect Immun 1994; 62: 4915-4921.
7. Feezor RJ, Oberholzer C, Baker HV, et al. Molecular characterization of the acute inflammatory response to infections with gram-negative versus gram-positive bacteria. Infect Immun 2003; 71: 5803-5813.
8. Kragsbjerg P, Jurstrand M, Fredlund H. Similar inflammatory response in human whole blood to live Streptococcus pneumoniae of different serotypes. Clin Microbiol Infect 2004; 10: 174-177.
9. Kopp E, Medzhitov R. Recognition of microbial infection by Toll-like receptors. Curr Opin Immunol 2003; 15: 396-401.
10. Underhill DM, Ozinsky A. Toll like receptors: key mediators of microbe detection. Curr Opin Immunol 2001; 14: 103-110.
11. Kirikae T, Nitta T, Kirikae F, et al. Lipopolysaccharides (LPS) of oral black-pigmented bacteria induce tumor necrosis factor production by LPS-refractory C3H/HeJ macrophages in a way different from that of Salmonella LPS. Infect Immun 1999; 67: 1736-1742.
12. Smith MF Jr, Mitchell A, Li G, et al. Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-B activation and chemokine expression by epithelial cells. J Biol Chem 2003; 278: 32552-32560.
13. Werts C, Tapping RI, Mathison JC et al. Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism. Nat Immunol 2001; 2: 346-352.
14. Morath S, Stadelmaier A, Geyer A, Schmidt RR, Hartung T. Synthetic lipoteichoic acid from Staphylococcus aureus is a potent stimulus of cytokine release. J Exp Med 2002; 195: 1635-1640.
15. Graves DT, Jiang Y, Genco C. Periodontal disease: bacterial virulence factors, host response and impact on systemic health. Curr Opin Infect Dis 2000; 13: 227232.
16. Gupta RS. What are archaebacteria, life's third domain or monoderm prokaryotes related to gram-positive bacteria? A new proposal for the classification of prokaryotic organisms. Mol Microbiol 1998; 29: 695-707.
17. Ellingsen E, Morath S, Flo T, et al. Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid. Involvement of Toll-like receptors and CD14. Med Sci Monit 2002; 8: 149-156.
18. Lawrence C, Nauciel C. Production of interleukin-12 by murine macrophages in response to bacterial peptidoglycan. Infect Immun 1998; 66: 4947-4949.
19. Mattsson E, Verhage L, Rollof J, Fleer A, Verhoef J, van Dijk H. Peptidoglycan and teichoic acid from Staphylococcus epidermidis stimulate human monocytes to release tumour necrosis factor-alpha, interleukin-1 beta and interleukin-6. FEMS Immunol Med Microbiol 1993; 7: 281-287.
20. Wang JE, Jorgensen PF, Almlof M, et al. Peptidoglycan and lipoteichoic acid from Staphylococcus aureus induce tumor necrosis factor alpha, interleukin 6 (IL-6), and IL-10 production in both T cells and monocytes in a human whole blood model. Infect Immun 2000; 68: 3965-3970.
21. Duncan L, Yoshioka M, Chandad F, Grenier D. Loss of lipopolysaccharide receptor CD14 from the surface of human macrophage-like cells mediated by Porphyromonas gingivalis outer membrane vesicles. Microb Pathog 2004; 36: 319-325.
22. Sugawara S, Nemoto E, Tada H, Miyake K, Imamura T, Takada H. Proteolysis of human monocyte CD14 by cysteine proteinases (gingipains) from Porphyromonas gingivalis leading to lipopolysaccharide hyporesponsiveness. J Immunol 2000; 165: 411-418.
23. Akira S. Toll-like receptors and innate immunity. Adv Immunol 2001; 78: 1-56.
24. Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001; 1: 135-145.
25. Schröder NW, Morath S, Alexander C, et al. Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR) -2, lipopolysaccharidebinding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved. J Biol Chem 2003; 278: 15587-15594.
26. Brandenburg K. Fourier transform infrared spectroscopy characterization of the lamellar and nonlamellar structures of free lipid A and Re lipopolysaccharides from Salmonella minnesota and Escherichia coli. Biophys J 1993; 64: 1215-1231.
27. Lüderitz O, Tanamoto K, Galanos C, et al. Lipopolysaccharides: structural principles and biologic activities. Rev Infect Dis 1984; 6: 428-431.
28. Coats SR, Reife RA, Bainbridge BW, Pham TT, Darveau RP. Porphyromonas gingivalis lipopolysaccharide antagonizes Escherichia coli lipopolysaccharide at toll-like receptor 4 in human endothelial cells. Infect Immun 2003; 71: 6799-6807.
29. Darveau RP, Pham TT, Lemley K, et al. Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. Infect Immun 2004; 72: 5041-5051.
30. Ogawa T, Asai Y, Hashimoto M, et al. Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway. Int Immunol 2002; 14: 1325-1232.
31. Netea MG, van Deuren M, Kullberg BJ, Cavaillon JM, Van der Meer JW. Does the shape of lipid A determine the interaction of LPS with Toll-like receptors? Trends Immunol 2002; 23: 135-139.
32. Nonnenmacher C, Dalpke A, Zimmermann S, Flores-De-Jacoby L, Mutters R, Heeg K. DNA from periodontopathogenic bacteria is immunostimulatory for mouse and human immune cells. Infect Immun 2003; 71: 850-856.
33. Nau GJ, Schlesinger A, Richmond JF, Young RA. Cumulative Toll-like receptor activation in human macrophages treated with whole bacteria. J Immunol 2003; 170: 5203-5209.