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Volumn 7, Issue 6, 2006, Pages 494-502

Mapping candidate non-MHC susceptibility regions to multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CHROMOSOME 13Q; CHROMOSOME 15Q; CHROMOSOME 17P; CHROMOSOME 18Q; CHROMOSOME 1P; CHROMOSOME 20P; CHROMOSOME 2P; CHROMOSOME 2Q; CHROMOSOME 3P; CHROMOSOME 7Q; CHROMOSOME ANALYSIS; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE MAPPING; GENETIC SUSCEPTIBILITY; GENOME ANALYSIS; HUMAN; IRELAND; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MULTIPLE SCLEROSIS; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION;

EID: 33748308913     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/sj.gene.6364320     Document Type: Article
Times cited : (12)

References (50)
  • 1
    • 0015492877 scopus 로고
    • HLA antigens and multiple sclerosis
    • Jersild C, Svejgaard A, Fog T. HLA antigens and multiple sclerosis. Lancet 1972; 2: 1240-1241.
    • (1972) Lancet , vol.2 , pp. 1240-1241
    • Jersild, C.1    Svejgaard, A.2    Fog, T.3
  • 2
    • 0009573338 scopus 로고    scopus 로고
    • A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex
    • the Multiple Sclerosis Genetics Group
    • Haines J, Pericak-Vance M, Seboun E, Hauser S, the Multiple Sclerosis Genetics Group. A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. Nat Genet 1996; 13: 469-471.
    • (1996) Nat Genet , vol.13 , pp. 469-471
    • Haines, J.1    Pericak-Vance, M.2    Seboun, E.3    Hauser, S.4
  • 3
    • 8844236880 scopus 로고    scopus 로고
    • A second-generation genomic screen for multiple sclerosis
    • (American-French Multiple Sclerosis Genetics Group)
    • Kenealy SJ, Babron MC, Bradford Y, Schnetz-Boutaud N, Haines JL, Rimmler JB, et al. (American-French Multiple Sclerosis Genetics Group). A second-generation genomic screen for multiple sclerosis. Am J Hum Genet 2004; 75 (6): 1070-1078.
    • (2004) Am J Hum Genet , vol.75 , Issue.6 , pp. 1070-1078
    • Kenealy, S.J.1    Babron, M.C.2    Bradford, Y.3    Schnetz-Boutaud, N.4    Haines, J.L.5    Rimmler, J.B.6
  • 4
  • 5
    • 15844368830 scopus 로고    scopus 로고
    • A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22
    • Sawcer S, Jones HB, Feakes R, Gray J, Smaldon N, Chataway J et al. A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat Genet 1996;13: 464-468.
    • (1996) Nat Genet , vol.13 , pp. 464-468
    • Sawcer, S.1    Jones, H.B.2    Feakes, R.3    Gray, J.4    Smaldon, N.5    Chataway, J.6
  • 6
    • 0142155199 scopus 로고    scopus 로고
    • Updated results of the United Kingdom linkage-based genome screen in multiple sclerosis
    • Hensiek AE, Roxburgh R, Smilie B, Coraddu F, Akesson E, Holmans P et al. Updated results of the United Kingdom linkage-based genome screen in multiple sclerosis. J Neuroimmunol 2003; 143: 25-30.
    • (2003) J Neuroimmunol , vol.143 , pp. 25-30
    • Hensiek, A.E.1    Roxburgh, R.2    Smilie, B.3    Coraddu, F.4    Akesson, E.5    Holmans, P.6
  • 8
    • 2542547323 scopus 로고    scopus 로고
    • An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: A report from the Canadian Collaborative Study Group
    • (Canadian Collaborative Study Group)
    • Dyment DA, Sadovnick AD, Willer CJ, Armstrong H, Cader ZM, Wiltshire S, et al. (Canadian Collaborative Study Group). An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: A report from the Canadian Collaborative Study Group. Hum Mol Genet 2004; 13 (10): 1005-1015.
    • (2004) Hum Mol Genet , vol.13 , Issue.10 , pp. 1005-1015
    • Dyment, D.A.1    Sadovnick, A.D.2    Willer, C.J.3    Armstrong, H.4    Cader, Z.M.5    Wiltshire, S.6
  • 13
    • 10744229264 scopus 로고    scopus 로고
    • A whole genome screen for linkage in Turkish multiple sclerosis
    • (Turkish Multiple Sclerosis Genetics Study Group)
    • Eraksoy M, Kurtuncu M, Akman-Demir G, Kilinc M, Gedizlioglu M, Mirza M, et al. (Turkish Multiple Sclerosis Genetics Study Group). A whole genome screen for linkage in Turkish multiple sclerosis. J Neuroimmunol 2003; 143: 17-24.
    • (2003) J Neuroimmunol , vol.143 , pp. 17-24
    • Eraksoy, M.1    Kurtuncu, M.2    Akman-Demir, G.3    Kilinc, M.4    Gedizlioglu, M.5    Mirza, M.6
  • 14
    • 23944499790 scopus 로고    scopus 로고
    • A high-density screen for linkage in multiple sclerosis
    • (for The International Multiple Sclerosis Genetics Consortium)
    • Sawcer S, Ban M, Maranian M, Yeo TW, Compston A, Kirby A, et al. (for The International Multiple Sclerosis Genetics Consortium). A high-density screen for linkage in multiple sclerosis. Am J Hum Genet 2005; 77: 454-467.
    • (2005) Am J Hum Genet , vol.77 , pp. 454-467
    • Sawcer, S.1    Ban, M.2    Maranian, M.3    Yeo, T.W.4    Compston, A.5    Kirby, A.6
  • 15
    • 0142155200 scopus 로고    scopus 로고
    • The Genetic Analysis of Multiple sclerosis in EuropeanS
    • GAMES
    • The Genetic Analysis of Multiple sclerosis in EuropeanS. GAMES. J Neuroimmunol 2003; 143: 1-140.
    • (2003) J Neuroimmunol , vol.143 , pp. 1-140
  • 16
    • 0142186253 scopus 로고    scopus 로고
    • A meta-analysis of whole genome linkage screens in multiple sclerosis
    • GAMES. Transatlantic Multiple Sclerosis Genetics Cooperative
    • GAMES. Transatlantic Multiple Sclerosis Genetics Cooperative. A meta-analysis of whole genome linkage screens in multiple sclerosis. J Neuroimmunol 2003; 143 (1-2): 39-46.
    • (2003) J Neuroimmunol , vol.143 , Issue.1-2 , pp. 39-46
  • 17
    • 24344436429 scopus 로고    scopus 로고
    • Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis
    • Fernald GH, Yeh RF, Hauser SL, Oksenberg JR, Baranzini SE. Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis. J Neuroimmunol 2005; 167 (1-2): 57-169.
    • (2005) J Neuroimmunol , vol.167 , Issue.1-2 , pp. 57-169
    • Fernald, G.H.1    Yeh, R.F.2    Hauser, S.L.3    Oksenberg, J.R.4    Baranzini, S.E.5
  • 18
    • 17044404608 scopus 로고    scopus 로고
    • SNP discovery in associating genetic variation with human disease phenotypes
    • Suh Y, Vijg J. SNP discovery in associating genetic variation with human disease phenotypes. Mutat Res 2005; 573 (1-2): 41-53.
    • (2005) Mutat Res , vol.573 , Issue.1-2 , pp. 41-53
    • Suh, Y.1    Vijg, J.2
  • 19
    • 17044419163 scopus 로고    scopus 로고
    • Genetic association studies of complex traits: Design and analysis issues
    • Newton-Cheh C, Hirschhorn JN. Genetic association studies of complex traits: Design and analysis issues. Mutat Res 2005; 573 (1-2): 54-69.
    • (2005) Mutat Res , vol.573 , Issue.1-2 , pp. 54-69
    • Newton-Cheh, C.1    Hirschhorn, J.N.2
  • 21
    • 10744231697 scopus 로고    scopus 로고
    • Investigation of seven proposed regions of linkage in multiple sclerosis: An American and French collaborative study
    • Pericak-Vance MA, Rimmler JB, Haines JL, Garcia ME, Oksenberg JR, Barcellos LF et al. Investigation of seven proposed regions of linkage in multiple sclerosis: An American and French collaborative study. Neurogenetics 2004; 5 (1): 45-48.
    • (2004) Neurogenetics , vol.5 , Issue.1 , pp. 45-48
    • Pericak-Vance, M.A.1    Rimmler, J.B.2    Haines, J.L.3    Garcia, M.E.4    Oksenberg, J.R.5    Barcellos, L.F.6
  • 22
    • 33645140430 scopus 로고    scopus 로고
    • Examination of seven candidate regions for multiple sclerosis: Strong evidence of linkage to chromosome 1q44
    • Kenealy SJ, Herrel LA, Bradford Y, Schnetz-Boutaud N, Oksenberg JR, Hauser SL et al. Examination of seven candidate regions for multiple sclerosis: Strong evidence of linkage to chromosome 1q44. Genes Immun 2006; 7 (1): 73-76.
    • (2006) Genes Immun , vol.7 , Issue.1 , pp. 73-76
    • Kenealy, S.J.1    Herrel, L.A.2    Bradford, Y.3    Schnetz-Boutaud, N.4    Oksenberg, J.R.5    Hauser, S.L.6
  • 23
    • 17444436401 scopus 로고    scopus 로고
    • The genetics of multiple sclerosis: Principles, background and updated results of the United Kingdom systematic genome screen
    • Chataway J, Feakes R, Coraddu F, Gray J, Deans J, Fraser M et al. The genetics of multiple sclerosis: Principles, background and updated results of the United Kingdom systematic genome screen. Brain 1998; 121 (Part 10): 1869-1887.
    • (1998) Brain , vol.121 , Issue.PART 10 , pp. 1869-1887
    • Chataway, J.1    Feakes, R.2    Coraddu, F.3    Gray, J.4    Deans, J.5    Fraser, M.6
  • 24
    • 18044399829 scopus 로고    scopus 로고
    • Genetic susceptibility to MS: A second stage analysis in Canadian MS families
    • Dyment DA, Willer CJ, Scott B, Armstrong H, Ligers A, Hillert J et al. Genetic susceptibility to MS: A second stage analysis in Canadian MS families. Neurogenetics 2001; 3 (3): 145-151.
    • (2001) Neurogenetics , vol.3 , Issue.3 , pp. 145-151
    • Dyment, D.A.1    Willer, C.J.2    Scott, B.3    Armstrong, H.4    Ligers, A.5    Hillert, J.6
  • 25
    • 0032961268 scopus 로고    scopus 로고
    • Linkage analysis of multiple sclerosis with candidate region markers in Sardinian and Continental Italian families
    • D'Alfonso S, Nistico L, Zavattari P, Marrosu MG, Murru R, Lai M et al. Linkage analysis of multiple sclerosis with candidate region markers in Sardinian and Continental Italian families. Eur J Hum Genet 1999; 7 (3): 377-385.
    • (1999) Eur J Hum Genet , vol.7 , Issue.3 , pp. 377-385
    • D'Alfonso, S.1    Nistico, L.2    Zavattari, P.3    Marrosu, M.G.4    Murru, R.5    Lai, M.6
  • 26
    • 0036263896 scopus 로고    scopus 로고
    • A whole genome screen for linkage disequilibrium in multiple sclerosis confirms disease associations with regions previously linked to susceptibility
    • Sawcer S, Maranian M, Setakis E, Curwen V, Akesson E, Hensiek A et al. A whole genome screen for linkage disequilibrium in multiple sclerosis confirms disease associations with regions previously linked to susceptibility. Brain 2002; 125 (Part 6): 1337-1347.
    • (2002) Brain , vol.125 , Issue.PART 6 , pp. 1337-1347
    • Sawcer, S.1    Maranian, M.2    Setakis, E.3    Curwen, V.4    Akesson, E.5    Hensiek, A.6
  • 28
    • 0034955141 scopus 로고    scopus 로고
    • Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis
    • Mcdonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD et al. Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001; 50 (1): 121-127.
    • (2001) Ann Neurol , vol.50 , Issue.1 , pp. 121-127
    • Mcdonald, W.I.1    Compston, A.2    Edan, G.3    Goodkin, D.4    Hartung, H.P.5    Lublin, F.D.6
  • 29
    • 0028909113 scopus 로고
    • Monte Carlo tests for associations between disease and alleles at highly polymorphic loci
    • Sham PC, Curtis D. Monte Carlo tests for associations between disease and alleles at highly polymorphic loci. Ann Hum Genet 1995; 59: 97-105.
    • (1995) Ann Hum Genet , Issue.59 , pp. 97-105
    • Sham, P.C.1    Curtis, D.2
  • 30
    • 10744223834 scopus 로고    scopus 로고
    • A genome wide scan for association with multiple sclerosis in a N. Irish case control population
    • Heggarty S, Sawcer S, Hawkins S, McDonnell G, Droogan A, Vandenbroeck K et al. A genome wide scan for association with multiple sclerosis in a N. Irish case control population. J Neuroimmunol 2003; 143 (1-2): 93-96.
    • (2003) J Neuroimmunol , vol.143 , Issue.1-2 , pp. 93-96
    • Heggarty, S.1    Sawcer, S.2    Hawkins, S.3    McDonnell, G.4    Droogan, A.5    Vandenbroeck, K.6
  • 32
    • 0344585289 scopus 로고    scopus 로고
    • Role of evolutionary history on haplotype block structure in the human genome: Implications for disease mapping
    • Tishkoff SA, Verrelli BC. Role of evolutionary history on haplotype block structure in the human genome: Implications for disease mapping. Curr Opin Genet Dev 2003; 13 (6): 569-575.
    • (2003) Curr Opin Genet Dev , vol.13 , Issue.6 , pp. 569-575
    • Tishkoff, S.A.1    Verrelli, B.C.2
  • 33
    • 28444460187 scopus 로고    scopus 로고
    • Multiple sclerosis genetics: Leaving no stone unturned
    • Oksenberg JR, Barcellos LF. Multiple sclerosis genetics: Leaving no stone unturned. Genes Immun 2005; 6 (5): 375-387.
    • (2005) Genes Immun , vol.6 , Issue.5 , pp. 375-387
    • Oksenberg, J.R.1    Barcellos, L.F.2
  • 34
    • 26644447610 scopus 로고    scopus 로고
    • Population frequency of HLA haplotypes contributes to the prevalence difference of multiple sclerosis in Ireland
    • McGuigan C, Dunne C, Crowley J, Hagan R, Rooney G, Lawlor E et al. Population frequency of HLA haplotypes contributes to the prevalence difference of multiple sclerosis in Ireland. J Neurol 2005; 252 (10): 1245-1248.
    • (2005) J Neurol , vol.252 , Issue.10 , pp. 1245-1248
    • McGuigan, C.1    Dunne, C.2    Crowley, J.3    Hagan, R.4    Rooney, G.5    Lawlor, E.6
  • 35
    • 0142155200 scopus 로고    scopus 로고
    • Genetic analysis of multiple sclerosis in Europeans
    • Barcellos LF, Thomson G. Genetic analysis of multiple sclerosis in Europeans. J Neuroimmunol 2003; 143 (1-2): 1-6.
    • (2003) J Neuroimmunol , vol.143 , Issue.1-2 , pp. 1-6
    • Barcellos, L.F.1    Thomson, G.2
  • 36
    • 27144538977 scopus 로고    scopus 로고
    • A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis
    • Lincoln MR, Montpetit A, Cader MZ, Saarela J, Dyment DA, Tiislar M et al. A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis. Nat Genet 2005; 37: 1108-1112.
    • (2005) Nat Genet , vol.37 , pp. 1108-1112
    • Lincoln, M.R.1    Montpetit, A.2    Cader, M.Z.3    Saarela, J.4    Dyment, D.A.5    Tiislar, M.6
  • 37
    • 21544476476 scopus 로고    scopus 로고
    • Association of the HLA region with multiple sclerosis as confirmed by a genome screen using > 10,000 SNPs on DNA chips
    • Godde R, Rohde K, Becker C, Toliat MR, Entz P, Suk A et al. Association of the HLA region with multiple sclerosis as confirmed by a genome screen using > 10,000 SNPs on DNA chips. J Mol Med 2005; 83 (6): 486-494.
    • (2005) J Mol Med , vol.83 , Issue.6 , pp. 486-494
    • Godde, R.1    Rohde, K.2    Becker, C.3    Toliat, M.R.4    Entz, P.5    Suk, A.6
  • 38
    • 0034303287 scopus 로고    scopus 로고
    • Linkage analysis of a candidate region in Scandinavian sib pairs with multiple sclerosis reveals linkage to chromosome 17q
    • Larsen F, Oturai A, Ryder LP, Madsen HO, Hillert J, Fredrikson S et al. Linkage analysis of a candidate region in Scandinavian sib pairs with multiple sclerosis reveals linkage to chromosome 17q. Genes Immun 2000; 1 (7): 456-459.
    • (2000) Genes Immun , vol.1 , Issue.7 , pp. 456-459
    • Larsen, F.1    Oturai, A.2    Ryder, L.P.3    Madsen, H.O.4    Hillert, J.5    Fredrikson, S.6
  • 41
    • 31044438675 scopus 로고    scopus 로고
    • HLA, CTLA-4 and PTPN22: The shared genetic master-key to autoimmunity?
    • Brand O, Gough S, Heward J. HLA, CTLA-4 and PTPN22: The shared genetic master-key to autoimmunity? Expert Rev Mol Med 2005; 7 (23): 1-15.
    • (2005) Expert Rev Mol Med , vol.7 , Issue.23 , pp. 1-15
    • Brand, O.1    Gough, S.2    Heward, J.3
  • 42
    • 0032707492 scopus 로고    scopus 로고
    • Genetic association studies of tumour necrosis factor alpha and beta and tumour necrosis factor receptor 1 and 2 polymorphisms across the clinical spectrum of multiple sclerosis
    • McDonnell GV, Kirk CW, Middleton D, Droogan AG, Hawkins SA, Patterson CC et al. Genetic association studies of tumour necrosis factor alpha and beta and tumour necrosis factor receptor 1 and 2 polymorphisms across the clinical spectrum of multiple sclerosis. J Neurol 1999; 246 (11): 1051-1058.
    • (1999) J Neurol , vol.246 , Issue.11 , pp. 1051-1058
    • McDonnell, G.V.1    Kirk, C.W.2    Middleton, D.3    Droogan, A.G.4    Hawkins, S.A.5    Patterson, C.C.6
  • 43
    • 0034688281 scopus 로고    scopus 로고
    • Functional regeneration of sensory axons into the adult spinal cord
    • Ramer MS, Priestley JV, McMahon SB. Functional regeneration of sensory axons into the adult spinal cord. Nature 2000; 403: 312-316.
    • (2000) Nature , vol.403 , pp. 312-316
    • Ramer, M.S.1    Priestley, J.V.2    McMahon, S.B.3
  • 44
    • 20144387851 scopus 로고    scopus 로고
    • Analysis of families in the Multiple Autoimmune Disease Genetics Consortium (MADGC) collection: The PTPN22 620W allele associates with multiple autoimmune phenotypes
    • Criswell LA, Pfeiffer K A, Lum RF, Gonzales B, Novitzke J, Kern M et al. Analysis of families in the Multiple Autoimmune Disease Genetics Consortium (MADGC) collection: The PTPN22 620W allele associates with multiple autoimmune phenotypes. Am J Hum Genet 2005; 76: 561-571.
    • (2005) Am J Hum Genet , vol.76 , pp. 561-571
    • Criswell, L.A.1    Pfeiffer, K.A.2    Lum, R.F.3    Gonzales, B.4    Novitzke, J.5    Kern, M.6
  • 45
    • 0036814534 scopus 로고    scopus 로고
    • F3/contactin. A neuronal cell adhesion molecule implicated in axogenesis and myelination
    • Falk J, Bonnon C, Girault JA, Faivre-Sarrailh C. F3/contactin. A neuronal cell adhesion molecule implicated in axogenesis and myelination. Biol Cell 2002; 94 (6): 327-334.
    • (2002) Biol Cell , vol.94 , Issue.6 , pp. 327-334
    • Falk, J.1    Bonnon, C.2    Girault, J.A.3    Faivre-Sarrailh, C.4
  • 46
    • 0037461768 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor alpha-7 subunit is an essential regulator of inflammation
    • Wang H, Yu M, Ochani M, Amella CA, Tanovic M, Susaria S et al. Nicotinic acetylcholine receptor alpha-7 subunit is an essential regulator of inflammation. Nature 2003; 421: 384-388.
    • (2003) Nature , vol.421 , pp. 384-388
    • Wang, H.1    Yu, M.2    Ochani, M.3    Amella, C.A.4    Tanovic, M.5    Susaria, S.6
  • 47
    • 7044260519 scopus 로고    scopus 로고
    • Activation of FAK and Src are receptor-proximal events required for netrin signaling
    • Li W, Lee J, Vikis HG, Lee SH, Liu G, Aurandt J et al. Activation of FAK and Src are receptor-proximal events required for netrin signaling. Nat Neurosci 2004; 7: 1213-1221.
    • (2004) Nat Neurosci , vol.7 , pp. 1213-1221
    • Li, W.1    Lee, J.2    Vikis, H.G.3    Lee, S.H.4    Liu, G.5    Aurandt, J.6
  • 48
    • 0034011003 scopus 로고    scopus 로고
    • The neural cell adhesion molecule in synaptic plasticity and ageing
    • Ronn LC, Berezin V, Bock E. The neural cell adhesion molecule in synaptic plasticity and ageing. Int J Dev Neurosci 2000; 18 (2-3): 193-199.
    • (2000) Int J Dev Neurosci , vol.18 , Issue.2-3 , pp. 193-199
    • Ronn, L.C.1    Berezin, V.2    Bock, E.3
  • 49
    • 0037456564 scopus 로고    scopus 로고
    • Metalloproteases: Carving out a role in axon guidance
    • McFarlane S. Metalloproteases: Carving out a role in axon guidance. Neuron 2003; 37 (4): 559-562.
    • (2003) Neuron , vol.37 , Issue.4 , pp. 559-562
    • McFarlane, S.1
  • 50
    • 0346788854 scopus 로고    scopus 로고
    • LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex
    • Carim-Todd L, Escarceller M, Estivill X, Sumoy L. LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex. Eur J Neurosci 2003; 18 (12): 3167-3182.
    • (2003) Eur J Neurosci , vol.18 , Issue.12 , pp. 3167-3182
    • Carim-Todd, L.1    Escarceller, M.2    Estivill, X.3    Sumoy, L.4


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