Expression profiles of elastase1 (NvElastaseI) and secretory leukocyte protease inhibitor (NvSLPI) during forelimb regeneration in adult Notophthalmus viridescens suggest a role in epithelial remodeling and delamination

Development Genes and Evolution

Volumn 216, Issue 9, 2006, Pages 499-509

  Vascotto, Sandy Gian ^a,b   Beug, Shawn ^a   Liversage, Richard A ^b   Tsilfidis, Catherine ^a  

^a UNIVERSITY OF OTTAWA EYE INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Elastase; Notophthalmus viridescens; Wound healing

Indexed keywords

PANCREATIC ELASTASE; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR;

AMPUTATION; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BLASTEMA; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM CELL; GENE EXPRESSION PROFILING; HUMAN; LIMB REGENERATION; NEWT; NONHUMAN; NUCLEOTIDE SEQUENCE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEQUENCE HOMOLOGY; SKIN EPITHELIUM; SKIN EXFOLIATION; TISSUE DIFFERENTIATION; UPREGULATION; WOUND HEALING;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; EPITHELIUM; FORELIMB; GENE EXPRESSION; IN SITU HYBRIDIZATION; MOLECULAR SEQUENCE DATA; NOTOPHTHALMUS VIRIDESCENS; PANCREATIC ELASTASE; REGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SECRETORY LEUKOCYTE PEPTIDASE INHIBITOR;

NOTOPHTHALMUS VIRIDESCENS; SALAMANDRIDAE;

EID: 33748093267     PISSN: 0949944X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00427-006-0061-z     Document Type: Article

References (63)

1. Alkemade JA, Molhuizen HO, Ponec M, Kempenaar JA, Zeeuwen PL, de Jongh GJ, van Vlijmen-Willems IM, van Erp PE, van de Kerkhof PC, Schalkwijk J (1994) SKALP/elafin is an inducible proteinase inhibitor in human epidermal keratinocytes. J Cell Sci 107(Pt 8):2335-2342
2. Ashcroft GS, Lei K, Jin W, Longenecker G, Kulkarni AB, Greenwell-Wild T, Hale-Donze H, McGrady G, Song XY, Wahl SM (2000) Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing. Nat Med 6:1147-1153
3. Bank U, Ansorge S (2001) More than destructive: Neutrophil-derived serine proteases in cytokine bioactivity control. J Leukoc Biol 69:197-206
4. Beer HD, Fassler R, Werner S (2000) Glucocorticoid-regulated gene expression during cutaneous wound repair. Vitam Horm 59:217-239
5. Bieth JG (1986) Elastases: Catalytic and biological properties. In: Mecham RP(ed) Biology of extracellular matrix: Regulation of matrix accumulation. Academic, New York, pp 217-320
6. Brockes JP (1997) Amphibian limb regeneration: Rebuilding a complex structure. Science 276:81-87
7. Brown T, Mackey K, Du T (2004) Analysis of RNA by Northern and slot blot hybridization. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (eds) Current protocols in molecular biology, Wiley, New York, NY, pp 4.9.1-4.9.16
8. Butler EG (1933) The effects of X-radiation on the regeneration of the forelimb of Amblystoma larvae. J Exp Zool 65:271-315
9. Cameron C, Beug S, Tsilfidis C (2004) Captive breeding of Notophthalmus viridescens through hormonal manipulation. Herpetol Rev 35:257-259
10. Chalkley DT (1954) A quantitative histological analysis of forelimb regeneration in Triturus viridescens. J Morph 94:21-70
11. Clarke BT (1997) The natural history of amphibian skin secretions, their normal functioning and potential medical applications. Biol Rev Camb Philos Soc 72:365-379
12. Echeverri K, Clarke JD, Tanaka EM (2001) In vivo imaging indicates muscle fiber dedifferentiation is a major contributor to the regenerating tail blastema. Dev Biol 236:151-164
13. Faisal Khan KM, Laurie GW, McCaffrey TA, Falcone DJ (2002) Exposure of cryptic domains in the alpha 1-chain of laminin-1 by elastase stimulates macrophages urokinase and matrix metalloproteinase-9 expression. J Biol Chem 277:13778-13786
14. Gardiner DM, Muneoka K, Bryant SV (1986) The migration of dermal cells during blastema formation in axolotls. Dev Biol 118:488-493
15. Gestin M, Le Huerou-Luron I, Wicker-Planquart C, Le Drean G, Chaix JC, Puigserver A, Guilloteau P (1997) Bovine pancreatic preproelastases I and II: Comparison of nucleotide and amino acid sequences and tissue specific expression. Comp Biochem Physiol Part B Biochem Mol Biol 118:181-187
16. Gibson TL, Cohen P (1999) Inflammation-related neutrophil proteases, cathepsin G and elastase, function as insulin-like growth factor binding protein proteases. Growth Horm IGF Res 9:241-253
17. Globus M, Vethamany-Globus S, Lee YC (1980) Effect of apical epidermal cap on mitotic cycle and cartilage differentiation in regeneration blastemata in the newt, Notophthalmus viridescens. Dev Biol 75:358-372
18. Hay ED (1959) Electron microscopic observations of muscle dedifferentiation in regenerating Amblystoma limbs. Dev Biol 1:555-585
19. Hayes TB, Gill TN (1995) Hormonal regulation of skin gland development in the toad (Bufo boreas): The role of the thyroid hormones and corticosterone. Gen Comp Endocrinol 99:161-168
20. Iten LE, Bryant SV (1973) Forelimb regeneration from different levels of amputation in the newt, Notophthalmus viridescens: Length, rate and stages. Wilhelm Roux - Archiv Dev Biol 173:263-282
21. Jorgensen CB (1988) Nature of moulting control in amphibians: Effects of cortisol implants in toads Bufo bufo. Gen Comp Endocrinol 71:29-35
22. Ju BG, Kim WS (2000) Cloning of a cDNA encoding cathepsin D from salamander, Hynobius leechii, and its expression in the limb regenerates. DNA Seq 11:21-28
23. Kato T, Miyazaki K, Shimizu-Nishikawa K, Koshiba K, Obara M, Mishima HK, Yoshizato K (2003) Unique expression patterns of matrix metalloproteinases in regenerating newt limbs. Dev Dyn 226:366-376
24. Kawamura K, Hayata D, Fujiwara S, Yubisui T (1998) Serine protease inhibitors expressed in the process of budding of tunicates as revealed by EST analysis. J Biochem (Tokyo) 124:1004-1012
25. Lapidot T, Petit I (2002) Current understanding of stem cell mobilization: The roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Exp Hematol 30:973-981
26. Leontovich AA, Zhang J, Shimokawa K, Nagase H, Sarras MP Jr (2000) A novel hydra matrix metalloproteinase (HMMP) functions in extracellular matrix degradation, morphogenesis and the maintenance of differentiated cells in the foot process. Development 127:907-920
27. Lheureux E, Carey F (1988) The irradiated epidermis inhibits newt limb regeneration by preventing blastema growth. A histological study. Biol Struct Morphog 1:49-57
28. Linden KG, Weinstein GD (1999) Psoriasis: Current perspectives with an emphasis on treatment. Am J Med 107:595-605
29. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-408
30. Mescher AL (1976) Effects on adult newt limb regeneration of partial and complete skin flaps over the amputation surface. J Exp Zool 195:117-128
31. Miyazaki K, Uchiyama K, Imokawa Y, Yoshizato K (1996) Cloning and characterization of cDNAs for matrix metalloproteinases of regenerating newt limbs. Proc Natl Acad Sci U S A 93:6819-6824
32. Morhenn VB (1997) Langerhans cells may trigger the psoriatic disease process via production of nitric oxide. Immunol Today 18:433-436
33. Muneoka K, Fox WF, Bryant SV (1986) Cellular contribution from dermis and cartilage to the regenerating limb blastema in axolotls. Dev Biol 116:256-260
34. Myat A, Henrique D, Ish-Horowicz D, Lewis J (1996) A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis. Dev Biol 174:233-247
35. Nace JD, Tassava RA (1995) Examination of fibronectin distribution and its sources in the regenerating newt limb by immunocytochemistry and in situ hybridization. Dev Dyn 202:153-164
36. Neufeld DA (1989) Epidermis, basement membrane, and connective-tissue healing after amputation of mouse digits: Implications for mammalian appendage regeneration. Anat Rec 223:425-432
37. Neufeld DA, Day FA, Settles HE (1996) Stabilizing role of the basement membrane and dermal fibers during newt limb regeneration. Anat Rec 245:122-127
38. Panyutich A, Shi J, Boutz PL, Zhao C, Ganz T (1997) Porcine polymorphonuclear leukocytes generate extracellular microbicidal activity by elastase-mediated activation of secreted proprotegrins. Infect Immun 65:978-985
39. Quinones JL, Rosa R, Ruiz DL, Garcia-Arraras JE (2002) Extracellular matrix remodeling and metalloproteinase involvement during intestine regeneration in the sea cucumber Holothuria glaberrima. Dev Biol 250:181-197
40. Rabinovitch M (1999) EVE and beyond, retro and prospective insights. Am J Physiol 277:L5-12
41. Ramaha A, Patston PA (2002) Release and degradation of angiotensin I and angiotensin II from angiotensinogen by neutrophil serine proteinases. Arch Biochem Biophys 397:77-83
42. Rocha-Pereira P, Santos-Silva A, Rebelo I, Figueiredo A, Quintanilha A, Teixeira F (2004) The inflammatory response in mild and in severe psoriasis. Br J Dermatol 150:917-928
43. Rogalski C, Meyer-Hoffert U, Proksch E, Wiedow O (2002) Human leukocyte elastase induces keratinocyte proliferation in vitro and in vivo. J Invest Dermatol 118:49-54
44. Simon A, Brockes JP (2002) Thrombin activation of S-phase reentry by cultured pigmented epithelial cells of adult newt iris. Exp Cell Res 281:101-106
45. Steen TP (1968) Stability of chondrocyte differentiation and contribution of muscle to cartilage during limb regeneration in the axolotl (Siredon mexicanum). J Exp Zool 167:49-78
46. Stocum DL (1985) Role of the skin in urodele limb regeneration. In: Sicard RE (ed) Regulation of vertebrate limb regeneration. Oxford University Press, New York, pp 32-53
47. Suomela S, Kariniemi AL, Snellman E, Saarialho-Kere U (2001) Metalloelastase (MMP-12) and 92-kDa gelatinase (MMP-9) as well as their inhibitors, TIMP-1 and -3, are expressed in psoriatic lesions. Exp Dermatol 10:175-183
48. Talas U, Dunlop J, Khalaf S, Leigh IM, Kelsell DP (2000) Human elastase 1: Evidence for expression in the skin and the identification of a frequent frameshift polymorphism. J Invest Dermatol 114:165-170
49. Tanaka EM, Brockes JP (1998) A target of thrombin activation promotes cell cycle re-entry by urodele muscle cells. Wound Repair Regen 6:371-381
50. Thompson RC, Ohlsson K (1986) Isolation, properties, and complete amino acid sequence of human secretory leukocyte protease inhibitor, a potent inhibitor of leukocyte elastase. Proc Natl Acad Sci U S A 83:6692-6696
51. Tsunemi M, Matsuura Y, Sakakibara S, Katsube Y (1996) Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution. Biochemistry 35:11570-11576
52. Vaday GG, Lider O (2000) Extracellular matrix moieties, cytokines, and enzymes: Dynamic effects on immune cell behavior and inflammation. J Leukoc Biol 67:149-159
53. Varani J, Burmeister B, Sitrin RG, Shollenberger SB, Inman DR, Fligiel SE, Gibbs DF, Johnson K (1994) Expression of serine proteinases and metalloproteinases in organ-cultured human skin. Altered levels in the presence of retinoic acid and possible relationship to retinoid-induced loss of epidermal cohesion. Am J Pathol 145:561-573
54. Vascotto SG, Beug S, Liversage RA, Tsilfidis C (2005) Identification of cDNAs associated with late dedifferentiation in adult newt forelimb regeneration. Dev Dyn 233:347-355
55. Vignali R, Nardi I (1996) Unusual features of the urodele genome: Do they have a role in evolution and development? Int J Dev Biol 40:637-643
56. Vinarsky V, Atkinson DL, Stevenson TJ, Keating MT, Odelberg SJ (2005) Normal newt limb regeneration requires matrix metalloproteinase function. Dev Biol 279:86-98
57. Wallace H (1981) Vertebrate limb regeneration. Wiley, Toronto
58. Wiedow O, Harder J, Bartels J, Streit V, Christophers E (1998) Antileukoprotease in human skin: An antibiotic peptide constitutively produced by keratinocytes. Biochem Biophys Res Commun 248:904-909
59. Wigle DA, Thompson KE, Yablonsky S, Zaidi SH, Coulber C, Jones PL, Rabinovitch M (1998) AML1-like transcription factor induces serine elastase activity in ovine pulmonary artery smooth muscle cells. Circ Res 83:52-263
60. Wingens M, van Bergen BH, Hiemstra PS, Meis JF, van Vlijmen-Willems IM, Zeeuwen PL, Mulder J, Kramps HA, van Ruissen F, Schalkwijk J (1998) Induction of SLPI (ALP/HUSI-I) in epidermal keratinocytes. J Invest Dermatol 111:996-1002
61. Yamada T (1977) Control mechanisms in cell-type conversion in newt lens regeneration. Monogr Dev Biol 13:1-126
62. Yang EV, Gardiner DM, Carlson MR, Nugas CA, Bryant SV (1999) Expression of Mmp-9 and related matrix metalloproteinase genes during axolotl limb regeneration. Dev Dyn 216:2-9
63. Zaidi SH, You XM, Ciura S, O'Blenes S, Husain M, Rabinovitch M (2000) Suppressed smooth muscle proliferation and inflammatory cell invasion after arterial injury in elafin-overexpressing mice. J Clin Invest 105:1687-1695