EVE and beyond, retro and prospective insights

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 277, Issue 1 21-1, 1999, Pages

  Rabinovitch, Marlene ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Elastase; Endogenous vascular elastase; Extracellular matrix; Fibronectin; Pulmonary hypertension; Tenascin

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; ELASTASE; EPIDERMAL GROWTH FACTOR; FIBRONECTIN; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; TENASCIN;

ANIMAL TISSUE; CELL MIGRATION; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME REGULATION; EXTRACELLULAR MATRIX; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

EID: 0032765385     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1999.277.1.l5     Document Type: Conference Paper

References (34)

1. Boudreau, N., N. Clausell, J. Boyle, and M. Rabinovitch. Transforming growth factor-β regulates increased ductus arteriosus endothelial glycosaminoglycan synthesis and a post-transcriptional mechanism controls increased smooth muscle fibronectin, features associated with intimai proliferation. Lab. Invest. 67: 350-359, 1992.
2. Boudreau, N., and M. Rabinovitch. Developmentally regulated changes in extracellular matrix in endothelial and smooth muscle cells in the ductus arteriosus may be related to intimal proliferation. Lab. Invest. 64: 187-199, 1991.
3. Boudreau, N., E. Turley, and M. Rabinovitch. Fibronectin, hyaluronan and a hyaluronan binding protein contribute to increased ductus arteriosus smooth muscle cell migration. Dev. Biol. 143: 235-247, 1991.
4. Clausell, N., S. Molossi, S. Sett, and M. Rabinovitch. In vivo blockade of tumor necrosis factor-a in cholesterol-fed rabbits after cardiac transplant inhibits acute coronary artery neointimal formation. Circulation 89: 2768-2779, 1994.
5. Clausell, N., and M. Rabinovitch. Upregulation of fibronectin synthesis by interleukin-1β in coronary artery smooth muscle cells is associated with the development of the post-cardiac transplant arteriopathy in piglets. J. Clin. Invest. 92: 1850-1858, 1992.
6. Cowan, B., O. Baron, J. Crack, C. Coulber, G. J. Wilson, and M. Rabinovitch. Elafin, a serine elastase inhibitor, attenuates post-cardiac transplant coronary arteriopathy and reduces myo-cardial necrosis in rabbits following heterotopic cardiac transplantation. J. Clin. Invest. 97: 2452-2468, 1996.
7. Hinek, A., J. Boyle, and M. Rabinovitch. Vascular smooth muscle cell detachment from elastin and migration through elastic laminae is promoted by chondroitin sulfate-induced "shedding" of the 67-kDa cell surface elastin binding protein. Exp. Cell Res. 203: 344-353, 1992.
8. Hinek, A., R. P. Mecham, F. Keeley, and M. Rabinovitch. Impaired elastin fiber assembly related to reduced 67-kD elastin-binding protein in fetal lamb ductus arteriosus and cultured aortic smooth muscle cells treated with chondroitin sulfate. J. Clin. Invest. 88: 2083-2094, 1991.
9. Hinek, A., S. Molossi, and M. Rabinovitch. Functional inter-play between interleukin-1 receptor and elastin binding protein controls fibronectin synthesis in coronary artery smooth muscle cells. Exp. Cell Res. 225: 122-131, 1996.
10. Hornebeck, W., J. C. Derouette, and L. Robert. Isolation, purification, and properties of aortic elastase. FEBS Lett. 58: 66-70, 1975.
11. Jones, P. L., K. N. Cowan, and M. Rabinovitch. Tenascin-C, proliferation and subendothelial fibronectin in progressive pulmonary vascular disease. Am. J. Pathol. 150: 1349-1360, 1997.
12. vβ3 integrin to promote epidermal growth factor receptor phosphorylation and growth. J. Cell Biol. 139: 279-293, 1997.
13. Jones, P. L., and M. Rabinovitch. Tenascin-C is induced with progressive pulmonary vascular disease in rats and is functionally related to increased smooth muscle cell proliferation, Circ. Res. 79: 1131-1142, 1996.
14. Kobayashi, J., D. Wigle, T. Childs, L. Zhu, F. W. Keeley, and M. Rabinovitch. Serum-induced vascular smooth muscle cell elastolytic activity through tyrosine kinase intracellular signalling. J. Cell. Physiol. 160: 121-131, 1994.
15. Maruyama, K., C. Ye, M. Woo, H. Venkatacharya, L. D. Lines, M. M. Silver, and M. Rabinovitch. Chronic hypoxic pulmonary hypertension in rats and increased elastolytic activity. Am. J. Physiol. 261 (Heart Circ. Physiol. 30): H1716-H1726, 1991.
16. Mason, C. A. E., P. Chang, C. Fallery, and M. Rabinovitch. Nitric oxide mediates LC-3 dependent regulation of fibronectin synthesis in ductus arteriosus smooth muscle cells. FASEB J. In press.
17. Meiners, S., M. Marone, J. L. Rittenhouse, and H. M. Geller. Regulation of astrocytic tenascin by basic fibroblast growth factor. Dev. Biol. 160: 480-493, 1993.
18. Molossi, S., N. Clausell, and M. Rabinovitch. Reciprocal induction of tumor necrosis factor-α and interleukin-1β activity mediates fibronectin synthesis in coronary artery smooth muscle cells. J. Cell. Physiol. 163: 19-29, 1995.
19. Molossi, S., M. Elices, T. Arrhenius, R. Diaz, C. Coulber, and M. Rabinovitch. Blockade of very late antigen-4 integrin binding to fibronectin with connecting segment-1 peptide reduces accelerated coronary arteriopathy in rabbit cardiac allografts. J. Clin. Invest. 95: 2601-2610, 1995.
20. 1 integrins. J. Cell. Physiol. 164: 620-633, 1995.
21. Nara, K., K. Ito, T. Ito, Y. Suzuki, M. A. Ghoneim, S. Tachibana, and S. Hirose. Elastase inhibitor elafin is a new type of proteinase inhibitor which has a transglutaminase-mediated anchoring sequence termed "cementoin". J. Biochem. (Tokyo) 115: 441-448, 1994.
22. Nuchprayoon, I., S. Meyers, L. M. Scott, J. Suzow, S. W. Hiebert, and A. D. Friedman. PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2β CBF beta protooncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells. Mol. Cell. Biol. 14: 5558-5568, 1994.
23. Oho, S., and M. Rabinovitch. Post-cardiac transplant arteriopathy in piglets is associated with fragmentation of elastin and increased activity of a serine elastase. Am. J. Pathol. 145: 202-210, 1994.
24. Rabinovitch, M., T. Bothwell, B. N. Hayakawa, W. G. Williams, G. A. Truster, R. D. Rowe, P. M. Olley, and E. Cutz. Pulmonary artery endothelial abnormalities in patients with congenital heart defects and pulmonary hypertension: a correlation of light with scanning electron microscopy and transmission electron microscopy. Lab. Invest. 55: 632-653, 1986.
25. Sallenave, J.-M., A. Silva, M. E. Marsden, and A. P. Ryle. Secretion of mucous proteinase inhibitor and elafin by Clara cell and type II pneumocyte cell lines. Am. J. Respir. Cell Mol. Biol. 8: 126-133, 1993.
26. Schalkwijk, J., A. Chang, P. Janssen, G. J. de Jongh, and P. Mier. Skin-derived antileucoproteases (SKALPs): characterization of two new elastase inhibitors from psoriatic epidermis. Br. J. Dermatol. 122: 631-641, 1990.
27. Thompson, E., J. Kobayashi, T. Childs, D. Wigle, and M. Rabinovitch. Endothelial and serum factors which include apolipoprotein A1 tether elastin to smooth muscle cells inducing serine elastase activity via tyrosine kinase-mediated transcription and translation. J. Cell. Physiol. 174: 78-89, 1998.
28. Thompson, K., and M. Rabinovitch. Exogenous leukocyte and endogenous elastases can mediate mitogenic activity in pulmonary artery smooth muscle cells by release of extracellular matrix-bound basic fibroblast growth factor. J. Cell. Physiol. 166: 495-505, 1995.
29. Todorovich-Hunter, L., H. Dodo, C. Ye, L. McCready, F. W. Keeley, and M. Rabinovitch. Increased pulmonary artery elastolytic activity in adult rats with monocrotaline-induced progressive hypertensive pulmonary vascular disease compared with infant rats with nonprogressive disease. Am. Rev. Respir. Dis. 146: 213-223, 1992.
30. Wigle, D., K. Thompson, S. Yablonsky, P. L. Jones, S. Zaidi, C. Coulber, and M. Rabinovitch. AML1-like transcription factor induces serine elastase activity in ovine pulmonary artery smooth muscle cells. Circ. Res. 83: 252-263, 1998.
31. Ye, C., and M. Rabinovitch. Inhibition of elastolysis by SC-37698 reduces development and progression of monocrotaline pulmonary hypertension. Am. J. Physiol. 261 (Heart Circ. Physiol. 30): H1255-H1267, 1991.
32. Zhou, B., N. Boudreau, C. Coulber, J. Hammarback, and M. Rabinovitch. Microtubule-associated protein 1 light chain 3 is a fibronectin mRNA-binding protein linked to mRNA translation in lamb vascular smooth muscle cells. J. Clin. Invest. 100: 3070-3082, 1997.
33. Zhu, L., E. Dagher, D. J. Johnson, D. Bedell-Hogan, F. W. Keeley, H. M. Kagan, and M. Rabinovitch. A developmentally regulated program restricting insolubilization of elastin and formation of laminae in the fetal lamb ductus arteriosus. Lab. Invest. 68: 321-331, 1993.
34. Zhu, L., D. Wigle, A. Hinek, J. Kobayashi, C. Ye, M. Zuker, H. Dodo, F. W. Keeley, and M. Rabinovitch. The endogenous vascular elastase that governs development and progression of monocrotaline-induced pulmonary hypertension in rats is a novel enzyme related to the serine proteinase adipsin. J. Clin. Invest. 94: 1163-1171, 1994.