Focal adhesions and associated proteins in medullary thyroid carcinoma cells

Journal of Surgical Research

Volumn 111, Issue 2, 2003, Pages 177-184

  Kim, Lawrence T ^a,c   Fleming, Jason B ^b   Lopez Guzman, Christie ^b   Nwariaku, Fiemu ^b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

Author keywords

Cell adhesion; Focal adhesions; Integrins; Medullary thyroid cancer; Protein tyrosine kinases

Indexed keywords

ACTIN; BETA1 INTEGRIN; FOCAL ADHESION KINASE; MATRIGEL; PAXILLIN; PHALLOIDIN; PHOSPHOTYROSINE; PROTEIN P130; RHODAMINE;

ARTICLE; CELL INVASION; COMPARATIVE STUDY; CONTROLLED STUDY; FOCAL ADHESION; HELA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MICROFILAMENT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THYROID MEDULLARY CARCINOMA; WESTERN BLOTTING;

ACTINS; ANTIGENS, CD29; BLOTTING, WESTERN; CARCINOMA, MEDULLARY; CRK-ASSOCIATED SUBSTRATE PROTEIN; CYTOSKELETAL PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; FOCAL ADHESION PROTEIN-TYROSINE KINASES; FOCAL ADHESIONS; IMMUNOSORBENT TECHNIQUES; MICROFILAMENTS; PAXILLIN; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTEINS; RETINOBLASTOMA-LIKE PROTEIN P130; SIGNAL TRANSDUCTION; THYROID NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0038016865     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Hofstra R.M., Landsvater R.M., Ceccherini I., Stulp R.P., Stelwagen T., Luo Y., Pasini B., Hoppener J.W., van Amstel H.K., Romeo G.A. mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma. Nature. 367:1994;375. [see comments].
2. Mulligan L.M., Kwok J.B., Healey C.S., Elsdon M.J., Eng C., Gardner E., Love D.R., Mole S.E., Moore J.K., Papi L. Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. Nature. 363:1993;458.
3. Donis-Keller H., Dou S., Chi D., Carlson K.M., Toshima K., Lairmore T.C., Howe J.R., Moley J.F., Goodfellow P., Wells S.A. Jr. Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC. Hum Mol Genet. 2:1993;851.
4. Murakami H., Iwashita T., Asai N., Iwata Y., Narumiya S., Takahashi M. Rho-dependent and -independent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130(Cas) mediated by Ret kinase. Oncogene. 18:1999;1975.
5. Miyamoto S., Akiyama S.K., Yamada K.M. Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science. 267:1995;883.
6. Sieg D.J., Hauck C.R., Ilic D., Klingbeil C.K., Schaefer E., Damsky C.H., Schlaepfer D.D. FAK integrates growth-factor and integrin signals to promote cell migration. Nat Cell Biol. 2:2000;249.
7. Kim L.T., Wu J., Bier-Laning C., Dollar B.T., Turnage R.H. Focal adhesion kinase up-regulation and signaling in activated keratinocytes. J Surg Res. 91:2000;65.
8. Bonifacio J.S. Protein labeling and immunoprecipitation. Bonifacio J.S., Dasso M., Harford J.B., Lippincott-Schwartz J., Yamada K.M. Current Protocols in Cell Biology. 2000;7.2.1-7.2.14 John Wiley & Sons, New York.