Coenzyme Q10 production in recombinant Escherichia coli strains engineered with a heterologous decaprenyl diphosphate synthase gene and foreign mevalonate pathway

Metabolic Engineering

Volumn 8, Issue 5, 2006, Pages 406-416

  Zahiri, Hossein Shahbani ^a   Yoon, Sang Hwal ^a   Keasling, Jay D ^b   Lee, Si Hyoung ^c   Won Kim, Seon ^a   Yoon, Sung Chul ^a   Shin, Yong Chul ^a,c  

^a Gyeongsang National University   (South Korea)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Amicogen Inc   (South Korea)

Author keywords

Coenzyme Q10; ddsA gene; Escherichia coli; IPP; Metabolic engineering; Mevalonate pathway

Indexed keywords

BACTERIOLOGY; CELL CULTURE; ENZYME KINETICS; GENES; PH EFFECTS;

COENZYME Q10; DDSA GENE; METABOLIC ENGINEERING; MEVALONATE PATHWAY;

ESCHERICHIA COLI;

4 HYDROXYBENZOIC ACID; DECAPRENYL DIPHOSPHATE SYNTHASE; ENZYME; GLYCEROL; ISOPENTENYL DIPHOSPHATE; MEVALONIC ACID; SODIUM CHLORIDE; UBIDECARENONE; UNCLASSIFIED DRUG; DECAPRENYL PYROPHOSPHATE SYNTHETASE; DRUG DERIVATIVE; RECOMBINANT PROTEIN; TRANSFERASE; UBIQUINONE;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; METABOLIC ENGINEERING; NONHUMAN; PH; PLASMID; PRIORITY JOURNAL; PRODUCTIVITY; SACCHAROMYCES CEREVISIAE; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES; YEAST; GENETIC ENHANCEMENT; GENETICS; METABOLISM; METHODOLOGY; PHYSIOLOGY; PROTEIN ENGINEERING; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE;

AGROBACTERIUM TUMEFACIENS; BACTERIA (MICROORGANISMS); ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; SACCHAROMYCES CEREVISIAE; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES;

ALKYL AND ARYL TRANSFERASES; ESCHERICHIA COLI; GENETIC ENHANCEMENT; MEVALONIC ACID; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; UBIQUINONE;

EID: 33747754525     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2006.05.002     Document Type: Article

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