Stem cells and their potential relevance to paediatric cardiology

Cardiology in the Young

Volumn 16, Issue 2, 2006, Pages 117-124

  Pillekamp, Frank ^a   Reppel, Michael ^a   Brockmeier, Konrad ^a   Hescheler, Jürgen ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Bioprosthesis; Cardiovascular diseases; Pluripotent stem cell; Therapy

Indexed keywords

AWARENESS; CELL CLONING; CELL DIFFERENTIATION; CELL FUSION; CELL GROWTH; CELL SURVIVAL; CELL TYPE; CHILD; CLINICAL STUDY; EMBRYO; EMBRYONIC STEM CELL; HEART ARRHYTHMIA; HEART DISEASE; HEART MUSCLE ISCHEMIA; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNE RESPONSE; MUSCLE REGENERATION; MYOBLAST; NONHUMAN; PEDIATRIC CARDIOLOGY; REGENERATIVE ABILITY; REVIEW; SOMATIC CELL; STEM CELL TRANSPLANTATION; TREATMENT INDICATION;

ADOLESCENT; BONE MARROW CELLS; CARDIOLOGY; CARDIOVASCULAR DISEASES; CHILD; CHILD, PRESCHOOL; HUMANS; INFANT; PEDIATRICS; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 33747707473     PISSN: 10479511     EISSN: 14671107     Source Type: Journal    
DOI: 10.1017/S1047951106000023     Document Type: Review

References (67)

1. Roell W, Lu ZJ, Bloch W, et al. Cellular cardiomyoplasty improves survival after myocardial injury. Circulation 2002; 105: 2435-2441.
2. Anversa P, Nadal-Ginard B. Myocyte renewal and ventricular remodeling. Nature 2002; 415: 240-243.
3. Winkel GA, Pederson RA. Fate of the inner cell mass in mouse embryos as studied by microinjection of lineage tracers. Dev Biol 1988; 127: 143-156.
4. Kolossov E, Lu Z, Drobinskaya I, et al. Identification and characterization of embryonic stem cell-derived pacemaker and atrial cardiomyocytes. FASEB J 2005; 19: 577-579.
5. Xue T, Cho HC, Akar FG, et al. Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: Insights into the development of cell-based pacemakers. Circulation 2005; 111, 11-20.
6. Rosen MR, Brink PR, Cohen IS, Robinson RB. Genes, stem cells and biological pacemakers. Cardiovasc Res 2004; 64: 12-23.
7. Sutherland FW, Perry TE, Yu Y, et al. From stem cells to viable autologous semilunar heart valve. Circulation 2005; 111: 2783-2791.
8. Neuenschwander S, Hoerstrup SP. Heart valve tissue engineering. Transpl Immunol 2004; 12: 359-365.
9. Hoenig MR, Campbell GR, Rolfe BE, Campbell JH. Tissue-engineered blood vessels: Alternative to autologous grafts? Arterioscler Thromb Vasc Biol 2005; 25: 1128-1134.
10. Sales KM, Salacinski HJ, Alobaid N, Mikhail M, Balakrishnan V, Seifalian AM. Advancing vascular tissue engineering: The role of stem cell technology. Trends Biotechnol 2005; 23: 461-467.
11. Winitsky SO, Gopal TV, Hassanzadeh S, et al. Adult murine skeletal muscle contains cells that can differentiate into beating cardiomyocytes in vitro. PloS Biol 2005; 3: E87.
12. Lee N, Thorne T, Losordo DW, Yoon YS. Repair of ischaemic heart disease with novel bone marrow-derived multipotent stem cells. Cell Cycle 2005; 4: 861-864.
13. Nygren JM, Jovinge S, Breitbach M, et al. Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat Med 2004; 10: 494-501.
14. Balsam LB, Wagers AJ, Christensen JL, Kofidis T, Weissman IL, Robbins RC. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature 2004: 428: 668-673.
15. Murry CE, Soonpaa MH, Reinecke H, et al. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 2004; 428: 664-668.
16. Laugwitz, KL, Moretti A, Lam J, et al. Postnatal ils1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature 2005; 433: 647-653.
17. Menasché P. Skeletal myoblast for cell therapy. Coron Artery Dis 2005; 16: 105-110.
18. Abraham MR, Henrikson CA, Tung L, et al. Antiarrhythmic engineering of skeletal myoblasts for cardiac transplantation. Circ Res 2005; 22: 159-167.
19. Leobon B, Garcin I, Menasché P, Vilquin JT, Audinat E, Charpak S. Myoblasts transplanted into rat infarcted myocardium are functionally isolated from their host. Proc Natl Acad Sci USA 2003; 100: 7808-7811.
20. Quaini F, Urbanek K, Beltrami AP, et al. Chimerism of the transplanted heart. N Engl J Med 2002; 346: 5-15.
21. Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41-49.
22. Pittenger MF, Martin BJ. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res 2004; 95: 9-20.
23. Yoon YS, Lee N, Scadova H. Myocardial regeneration with bone-marrow derived stem cells. Biol Cell 2005; 97: 253-263.
24. Beltrami AP, Urbanek K, Kajstura J, et al. Evidence that human cardiac myocytes divide after myocardial infarction. N Engl J Med 2001: 344; 1750-1757.
25. Beltrami AP, Barlucchi L, Torella D, et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003; 114: 763-776.
26. Oh H, Bradfute SB, Gallardo TD, et al. Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction. Proc Natl Acad Sci USA 2003; 100: 12313-12318.
27. Messina E, De Angelis L, Frati G, et al. Isolation and expansion of adult cardiac stem cells from human and murine hearts. Circ Res 2004; 95: 911-921.
28. Urbanek K, Quaini F, Tasca G, et al. Intense myocytes formation from cardiac stem cells in human cardiac hypertrophy. Proc Natl Acad Sci USA 2003; 100: 10440-10445.
29. Orlic D, Krajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001; 410: 701-705.
30. Kajstura J, Rota M, Whang B, et al. Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion. Circ Res 2005; 96: 127-137.
31. Wagers AJ, Weissman IL. Plasticity of adult stem cells. Cell 2004; 116: 639-648.
32. Chen EH, Olson EN. Unveiling the mechanisms of cell-cell fusion. Science 2005; 308: 369-373
33. Carmago FD, Chambers SM, Goodell MA. Stem cell plasticity: From transdifferentiation to macrophage fusion. Cell Prolif 2004; 37: 55-65.
34. O'Malley K, Scott EW. Stem cell fusion confusion. Exp Hematol 2004; 32: 131.
35. Do JT, Scholer HR. Nuclei of embryonic stem cells reprogram somatic cells. Stem Cells 2004; 22: 941-949.
36. Wollert KC, Meyer GP, Lotz J, et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: The BOOST randomised controlled clinical trial. Lancet 2004; 364: 141-148.
37. Anversa P, Kajstura J. Ventricular myocytes are not terminally differentiated in the adult mammalian heart. Circ Res 1998; 183: 1-4.
38. Nadal-Ginard B, Kajstura J, Leria A, Anversa P. Myocyte death, growth, and regeneration in cardiac hypertrophy and failure. Circ Res 2003; 92: 139-150.
39. Spradling A, Drummond-Barbose D, Kai T. Stem cells find their niche. Nature 2001; 414: 98-104.
40. Cai CL, Liang X, Shi Y, et al. Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell 2003; 5: 877-889.
41. Parmacek MS, Epstein JA. Pursuing cardiac progenitors: Regeneration redux. Cell 2005; 120: 295-298.
42. Thomson JA, Iskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282: 1145-1157.
43. Xu RH, Peck RM, Li DS, Feng X, Ludwig T, Thomson JA. Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods 2005; 2: 185-190.
44. Itskovitz-Eldor J, Schuldiner M, Karsenti D, et al. Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Mol Med 2000; 6: 88-95.
45. Reppel M, Boettinger C, Hescheler J. Beta adrenergic and muscarinic modulation of human embryonic stem cell-derived cardiomyocytes. Cell Physiol Biochem 2004; 14: 187-196.
46. Kehat I, Khimovich L, Caspi O, et al. Electromechanical integration of cardiomyocytes derived from human embryonic stem cells. Nat Biotechnol 2004; 22: 1282-1289.
47. Agbulut O, Menot ML, Li Z, et al. Temporal patterns of bone marrow cell differentiation following transplantation in doxorubicin-induced cardiomyopathy. Cardiovasc Res 2003; 58: 451-459.
48. Wang JF, Yang Y, Wang G, et al. Embryonic stem cells attenuate viral myocarditis in murine model. Cell Transplant 2002; 11: 753-758.
49. Yoon YS, Park JS, Tkebuchava T, Luedeman C, Losordo DW. Unexpected severe calcification after transplantation of bone marrow cells in acute myocardial infarction. Circulation 2004; 109: 3154-3157.
50. Maltsev VA, Rohwedel J, Hescheler J, Wobus AM. Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types. Mech Dev 1993; 44: 41-50.
51. Gassanov N, Er F, Zgidullin N, Hoppe UC. Endothelin induces differentiation of ANP-EGFP expressing embryonic stem cells towards a pacemaker phenotype. FASEB J 2004; 18: 1710-1712.
52. Couzin J, Vogel G. Cell therapy. Renovating the heart. Science 2004; 304: 192-194.
53. Gutstein DE, Danik SB, Lewilton S, et al. Focal gap junction uncoupling and spontaneous ventricular ectopy. Am J Physiol Heart Circ Physiol 2005; 289: H1091-H1098.
54. Gutstein DE, Morley GE, Tamaddon H, et al. Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin 43. Circ Res 2001; 88: 333-339.
55. Li L, Xie T. Stem cell niche: Structure and function. Annu Rev Cell Dev Biol 2004; [Epub ahead of print)
56. Bradley JA, Bolton EM, Pedersen RA. Stem cell medicine encounters the immune system. Nat Rev Immunol 2002; 2: 859-871.
57. Xiao YF, Min JY, Morgan JP. Immunosuppression and xenotrans-plantation of cells for cardiac repair. Ann Thorac Surg 2004; 77: 737-744.
58. Drukker M, Benvenisty N. The immunogenicity of human embryonic stem-derived cells. Trends Biotechnol 2004; 22: 136-141.
59. Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005; 105: 1815-1822.
60. Kim JY, Kim D, Choi I, et al. MHC expression in a human adult stem cell line and its down-regulation by hCMV US gene transfection. Int J Biochem Cell Biol 2005; 37: 69-78.
61. Hochedlinger K, Jaenisch R. Nuclear transplantation, embryonic stem cells, and the potential for cell therapy. NEJM 2003; 349: 275-286.
62. Pomerantz J, Blau HM. Nuclear reprogramming: A key to stem cell function in regenerative medicine. Nat Cell Biol 2004; 6: 810-816.
63. Jaenisch R. Human cloning - the science and ethics of nuclear transplantation. N Engl J Med 2004; 351: 27.
64. McHugh PR. Zygote and "clonoate" - the ethical use of embryonic stem cells. N Engl J Med 2004; 351: 209-211.
65. Antoniou M. Embryonic stem cell research. The case against ... Nat Med 2001; 7: 396-397.
66. McLaren A. Ethical and social considerations of stem cell research. Nature 2001; 414: 129-131.
67. Winston R. Embryonic stem cell research. The case for ... Nat Med 2001; 7: 397-399.