RNAi technology: A revolutionary tool for the colorectal cancer therapeutics

World Journal of Gastroenterology

Volumn 12, Issue 29, 2006, Pages 4636-4639

  Lv, Wei ^a   Zhang, Chao ^a   Hao, Jia ^a  

^a SOUTHWEST HOSPITAL   (China)

Author keywords

Colorectal cancer; RNAi; Therapeutics

Indexed keywords

BETA CATENIN; BETA TUBULIN; DAUNORUBICIN; DNA METHYLTRANSFERASE 1; DOUBLE STRANDED RNA; DOXORUBICIN; ETOPOSIDE; K RAS PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; PROTEIN BCL 2; RETROVIRUS VECTOR; SMALL INTERFERING RNA; VASCULOTROPIN; VINBLASTINE; VINCRISTINE;

CANCER CHEMOTHERAPY; CANCER INCIDENCE; CANCER INHIBITION; CANCER MORTALITY; CANCER RADIOTHERAPY; CANCER STATISTICS; CANCER SURVIVAL; CARCINOGENICITY; CHINA; COLORECTAL CANCER; COLORECTAL SURGERY; DIETARY INTAKE; DIGESTIVE SYSTEM TUMOR; DNA VECTOR; DRUG MECHANISM; GENE DELIVERY SYSTEM; GENE FUNCTION; GENE TECHNOLOGY; GENETIC PROCEDURES; HUMAN; LIFESTYLE; MORBIDITY; MULTIMODALITY CANCER THERAPY; NONHUMAN; POSTTRANSCRIPTIONAL GENE SILENCING; REVIEW; RNA DEGRADATION; RNA INTERFERENCE; RNA SYNTHESIS; SEQUENCE HOMOLOGY; SEX RATIO; VIRUS INHIBITION; WESTERN HEMISPHERE;

EID: 33747646888     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v12.i29.4636     Document Type: Review

References (35)

1. Hammond SM, Caudy AA, Hannon GJ. Post-transcriptional gene silencing by double-stranded RNA. Nat Rev Genet 2001; 2: 110-119
2. Hutvagner G, Zamore PD. RNAi: nature abhors a double-strand. Curr Opin Genet Dev 2002; 12: 225-232
3. Bergstrom CT, Antia R. On RNA interference as template immunity. J Biosci 2005; 30: 295-297
4. Waterhouse PM, Wang MB, Lough T. Gene silencing as an adaptive defence against viruses. Nature 2001; 411: 834-842
5. Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811
6. Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 2001; 15: 188-200
7. Elbashir SM, Martinez J, Patkaniowska A, Lendeckel W, Tuschl T. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J 2001; 20: 6877-6888
8. Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 2001; 409: 363-366
9. Billy E, Brondani V, Zhang H, Muller U, Filipowicz W. Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines. Proc Natl Acad Sci USA 2001; 98: 14428-14433
10. Yin D, Stuart CA. Gene silencing using small interference RNA in mast cells. Methods Mol Biol 2006; 315: 333-339
11. Cerutti L, Mian N, Bateman A. Domains in gene silencing and cell differentiation proteins: the novel PAZ domain and redefinition of the Piwi domain. Trends Biochem Sci 2000; 25: 481-482
12. Hammond SM, Bernstein E, Beach D, Hannon GJ. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 2000; 404: 293-296
13. Williams RW, Rubin GM. ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos. Proc Natl Acad Sci USA 2002; 99: 6889-6894
14. Hammond SM, Boettcher S, Caudy AA, Kobayashi R, Hannon GJ. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 2001; 293: 1146-1150
15. Nykanen A, Haley B, Zamore PD. ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 2001; 107: 309-321
16. Boutla A, Delidakis C, Livadaras I, Tsagris M, Tabler M. Short 5′-phosphorylated double-stranded RNAs induce RNA interference in Drosophila. Curr Biol 2001; 11: 1776-1780
17. Sijen T, Fleenor J, Simmer F, Thijssen KL, Parrish S, Timmons L, Plasterk RE, Fire A. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 2001; 107: 465-476
18. Donze O, Picard D. RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res 2002; 30: e46
19. Paddison PJ, Caudy AA, Bernstein E, Hannon GJ, Conklin DS. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev 2002; 16: 948-958
20. Yu JY, DeRuiter SL, Turner DL. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 2002; 99: 6047-6052
21. Lee NS, Dohjima T, Bauer G, Li H, Li MJ, Ehsani A, Salvaterra P, Rossi J. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 2002; 20: 500-505
22. Miyagishi M, Taira K. U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat Biotechnol 2002; 20: 497-500
23. Paul CP, Good PD, Winer I, Engelke DR. Effective expression of small interfering RNA in human cells. Nat Biotechnol 2002; 20: 505-508
24. Sui G, Soohoo C, Affar el B, Gay F, Shi Y, Forrester WC, Shi Y. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 2002; 99: 5515-5520
25. Harper SQ, Davidson BL. Plasmid-based RNA interference: construction of small-hairpin RNA expression vectors. Methods Mol Biol 2005; 309: 219-235
26. Holash J, Davis S, Papadopoulos N, Croll SD, Ho L, Russell M, Boland P, Leidich R, Hylton D, Burova E, Ioffe E, Huang T, Radziejewski C, Bailey K, Fandl JP, Daly T, Wiegand SJ, Yancopoulos GD, Rudge JS. VEGF-Trap: a VEGF blocker with potent antitumor effects. Proc Natl Acad Sci USA 2002; 99: 11393-11398
27. Martinez LA, Naguibneva I, Lehrmann H, Vervisch A, Tchenio T, Lozano G, Harel-Bellan A. Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways. Proc Natl Acad Sci USA 2002; 99: 14849-14854
28. Lin SL, Chuong CM, Ying SY. A Novel mRNA-cDNA interference phenomenon for silencing bcl-2 expression in human LNCaF cells. Biochem Biophys Res Commun 2001; 281: 639-644
29. Nieth C, Priebsch A, Stege A, Lage H. Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi). FEBS Lett 2003; 545: 144-150
30. Kosciolek BA, Kalantidis K, Tabler M, Rowley PT. Inhibition of telomerase activity in human cancer cells by RNA interference. Mol Cancer Ther 2003; 2: 209-216
31. Lu X, Errington J, Curtin NJ, Lunec J, Newell DR. The impact of p53 status on cellular sensitivity to antifolate drugs. Clin Cancer Res 2001; 7: 2114-2123
32. Williams NS, Gaynor RB, Scoggin S, Verma U, Gokaslan T, Simmang C, Fleming J, Tavana D, Frenkel E, Becerra C. Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference. Clin Cancer Res 2003; 9: 931-946
33. De Marzo AM, Marchi VL, Yang ES, Veeraswamy R, Lin X, Nelson WG. Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis. Cancer Res 1999; 59: 3855-3860
34. Matsukura S, Jones PA, Takai D. Establishment of conditional vectors for hairpin siRNA knockdowns. Nucleic Acids Res 2003; 31: e77
35. Sakamoto KM. Knocking down human disease: potential uses of RNA interference in research and gene therapy. Pediatr Res 2004; 55: 912-913