Chapter 10. Emerging Opportunities in the Treatment of Atherosclerosis

Annual Reports in Medicinal Chemistry

Volumn 32, Issue C, 1997, Pages 101-110

  Hayward, Cheryl M ^a   Bamberger, Mark J ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33747505815     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-7743(08)61468-2     Document Type: Article

References (83)

1. 1997 Heart and Stroke Statistical Update, American Heart Association: Dallas, TX (1997)
2. Scandinavian Simvastatin Survival Study Group. Lancet 344 (1994) 1383
3. Shepherd J., Cobbe S.M., Ford I., Isles C.G., Lorimer A.R., Macfarlane P.W., McKillop J.H., and Packard C.J. N. Eng. J. Med. 333 (1995) 1301
4. NCEP panel. Circulation 89 (1994) 1329
5. Bakker-Arkema R.G., Davidson M.H., Goldstein R.J., Davignon J., Isaacsohn J.L., Weiss S.R., Keilson L.M., Brown W.V., Miller V.T., Shurzinske L.J., and Black D.M. JAMA 275 (1996) 128
6. Davidson M.H., Stein E.A., Dujovne C.A., Hunninghake D.B., Weiss S.R., Knopp R.H., Illingworth D.R., Mitchel Y.B., Melino M.R., Zupkis R.V., Dobrinska M.R., Amin R.D., and Tobert J.A. Am. J. Cardiol. 79 (1997) 38
7. Chang G., and Ruggeri R.B. Exp. Opin. Ther. Patents 7 (1997) in press
8. Lee H.T., and Picard J.A. Exp. Opin. Ther. Patents 5 (1995) 397
9. Krause B.R., Sliskovic D.R., and Bocan T.M.A. Exp. Opin. Invest. Drugs 4 (1995) 353
10. Biller S.A., Neuenschwander K., Ponpipom M.M., and Poulter C.D. Current Pharmaceutical Design 2 (1996) 1
11. Halazy S., and Gotteland J.-P. Exp. Opin. Ther. Patents 6 (1996) 1165
12. Dickson Jr. J.K., Biller S.A., Magnin D.R., Petrillo Jr. E.W., Hillyer J.W., Hsieh D.C., Lan S.-J., Rinehart J.K., Gregg R.E., Harrity T.W., Jolibois K.G., Kalinowski S.S., Kunselman L.K., Mookhtiar K.A., and Ciosek Jr. C.P. J. Med. Chem. 39 (1996) 661
13. T. W. Harrity, R. J. George, C. P. Ciosek, Jr., S. A. Biller, Y. Chen, J. K. Dickson, Jr., O. M. Fryszman, K. J. Jolibois, L. K. Kunselman, R. M. Lawrence, J. V. H. Logan, D. R. Magnin, L. C. Rich, D. A. Slusarchyk, R. B. Sulsky and R. E. Gregg, Abstracts, XII International Symposium on Drugs Affecting Lipid Metabolism, Houston, TX, November 7-10: 54(1995)
14. J. D. Bergstrom, Abstracts, XII International Symposium on Drugs Affecting Lipid Metabolism, Houston, TX, November 7-10: 6(1995)
15. Bostedor R.G., Karkas J.D., Arison B.H., Bansal V.S., Vaidya S., Germershausen J.I., Kurtz M.M., and Bergstrom J.D. J. Biol. Chem. 272 (1997) 9197
16. McCarthy P.A., DeNinno M.P., Morehouse L.A., Chandler C.E., Bangerter F.W., Wilson T.C., Urban F.J., Walinsky S.W., Cosgrove P.G., Duplantier K., Etienne J.B., Fowler M.A., Lambert J.F., O'Donnell J.P., Pezzullo S.L., Watson Jr. H.A., Wilkins R.W., Zaccaro L.M., and Zawistoski M.P. J. Med. Chem. 39 (1996) 1935
17. W. S. Harris, S. L. Windsor, F. A. Newton and R. A. Gelfand, Abstracts, XII International Symposium on Drugs Affecting Lipid Metabolism, Houston, TX, November 7-10: 135(1995)
18. M. P. DeNinno, P. A. McCarthy, J. B. Etienne, C. Eller, K. C. Duplantier, C. E. Chandler and L. A. Morehouse, Abstract Publication, 20th IUPAC Symposium on the Chemistry of Natural Products, Chicago, IL, September 15-20: BM-12(1996)
19. M. Bergman, H. Morales, L. Mellars, T. Kosoglou, R. Burrier, H. R. Davis, E. J. Sybertz and T. Pollare, Abstracts, XII International Symposium on Drugs Affecting Lipid Metabolism, Houston, TX, November 7-10: 5(1995)
20. Salisbury B.G., Davis H.R., Burrier R.E., Burnett D.A., Boykow G., Caplen M.A., Clemmons A.L., Compton D.S., Hoos L.M., McGregor D.G., Schnitzer-Polokoff R., Smith A.A., Weig B.C., Zilli D.L., Clader J.W., and Sybertz E.J. Atherosclerosis 115 (1995) 45
21. Dugar S., Yumibe N., Clader J.W., Vizziano M., Huie K., Van Heek M., Compton D.S., and Davis Jr. H.R. Biorg. Med. Chem. Lett. 6 (1996) 1271
22. Kirkup M.P., Rizvi R., Shankar B.B., Dugar S., Clader J.W., McCombie S.W., Lin S.-I., Yumibe N., Huie K., Van Heek M., Compton D.S., and Davis Jr. H.R. Biorg. Med. Chem. Lett. 6 (1996) 2069
23. S. B. Rosenblum, T. Huynh, H. Davis, N. Yumibe, J. Clader, A. Afonso and D. Burnett, Abstracts, XII International Symposium on Drugs Affecting Lipid Metabolism, Houston, TX, November 7-10: 61(1995)
24. Carr T.P., Parks J.S., and Rudel L.L. Arterioscler. Thromb. Vasc. Biol. 12 (1992) 1274
25. Sliskovic D.R., and Trivedi B.K. Current Medicinal Chemistry 1 (1994) 204
26. Matsunda K. Medicinal Research Reviews 14 (1994) 271
27. Lee H.T., Sliskovic D.R., Picard J.A., Roth B.D., Wierenga W., Hicks J.L., Bousley R.F., Hamelehle K.L., Homan R., Speyer C., Stanfield R.L., and Krause B.R. J. Med. Chem. 39 (1996) 5031
28. Benson G.M., and Hickey D.M.B. Exp. Opin. Invest. Drugs 3 (1994) 493
29. J. Billheimer, R. Fischer, S. Germain, G. Figuly, J. Jensen, S. Royce, M. Gorko, J. Hainer and P. Gillies, Abstracts, XII International Symposium on Drugs Affecting Lipid Metabolism, Houston, TX, November 7-10: 139(1995)
30. D. I. Goldberg, B. Sacchiero, D. Rosenbaum, M. Pitruzzello, C. Maloney, J. Ward, K. Miller, S. R. Holmes-Farley, B. Nicolosi and W. H. Mandeville, Abstracts, XII International Symposium on Drugs Affecting Lipid Metabolism, Houston, TX, November 7-10: 6(1995)
31. Y. Homma, T. Kobayashi, H. Ozawa, H. Yamaguchi and H. Sakane, Abstracts, XII International Symposium on Drugs Affecting Lipid Metabolism, Houston, TX, November 7-10: 59(1995)
32. Falcone M., Miyamoto T., Fierro-Renoy F., Macchia E., and DeGroot L.J. Endocrinology 131 (1992) 2419
33. Ness G.C., and Zhao Z. Arch. Biochem. Biophys. 315 (1994) 199
34. Polikar R., Burger A.G., Scherrer U., and Nicod P. Circulation 87 (1993) 1435
35. Stephan Z.F., Yurachek E.C., Sharif R., Wasvary J.M., Leonards K.S., Hu C.-W., Hintze T.H., and Steele R.E. Atherosclerosis 126 (1996) 53
36. Sharp D., Blinderman L., Combs K.A., Kienzle B., Ricci B., Wager-Smith K., Gil C.M., Turck C.W., Bouma M.-E., Rader D.J., Aggerbeck L.P., Gregg R.E., Gordon D.A., and Wetterau J.R. Nature 365 (1993) 65
37. Jamil H., Gordon D.A., Eustice D.C., Brooks C.M., Dickson Jr. J.K., Chen Y., Ricci B., Chu C.-H., Harrity T.W., Ciosek Jr. C.P., Biller S.A., Gregg R.E., and Wetterau J.R. Proc. Natl. Acad. Sci. USA 93 (1996) 11991
38. Harrity T.W., Connolly F.J., Kunselman L.K., Dickson Jr. J.K., Jolibois K.G., Magnin D.R., Gordon D.A., Tino J.A., Jamil J., Logan J.J., and Yan M. Circulation 94 8 Suppl (1996) 1632
39. U. Mueller, R. Connell, S. Goldmann, R. Gruetzmann, M. Beuck and H. Bischoff, EP 0705831(1996)
40. J. Heeres, L. J. J. Backx, P. A. C. Luyts and D. R. G. De Chaffoy De Courcelles, WO 9633193(1996)
41. Johnson W.J., Mahlberg F.H., Rothblat G.H., and Phillips M.C. Biochim. Biophys. Acta 1085 (1991) 273
42. Oram J.F., and Yokoyama S. J.Lipid Res. 37 (1996) 2473
43. Fielding C.J., and Fielding P.E. J.Lipid Res. 36 (1995) 211
44. Tato F., Vega G.L., and Grundy S.M. Arterioscler. Thromb. Vasc. Biol. 17 (1997) 56
45. Stone N.J. Am. J. Med. 101 suppl 4A (1996) 40S
46. Tall A. Ann. Rev. Biochem. 64 (1995) 235
47. Inazu A., Brown M.L., Hesler C.B., Agellon L.B., Koizumi J., Takata K., Maruhama Y., Mabuchi H., and Tall A.R. N. Engl. J. Med. 323 (1990) 1234
48. Marotti K.R., Castle C.K., Boyle T.P., Lin A.H., Murray R.W., and Melchior G.W. Nature 364 (1993) 73
49. McPherson R., Mann C.J., Tall A.R., Hogue M., Martin L., Milne R.W., and Marcel Y.L. Arterioscler. Thromb. Vasc. Biol. 11 (1991) 797
50. Hayek T., Masucci-Magoulas L., Jiang X., Walsh A., Rubin E., Breslow J.L., and Tall A.R. J. Clin. Invest. 96 (1995) 2071
51. Zhong S., Sharp D.S., Grove J.S., Bruce C., Yano K., Curb J.D., and Tall A.R. J. Clin. Invest. 97 (1996) 2917
52. Bisgaier C.L., Essenburg A.D., Minton L.L., Homan R., Blankley C.J., and White A. Lipids 29 (1994) 811
53. Kothari H.V., Poirier K.J., Lee W.H., and Satoh Y. Atherosclerosis 128 (1997) 59
54. Xia Y., Mirzai B., Chackalamannil S., Czamiecki M., Wang S., Clemmons A., Ahn H.-S., and Boykow G.C. Biorg. Med. Chem. Lett. 6 (1996) 919
55. Chackalamannil S., Xia Y., Wang Y., Tsai H., Czamiecki M., Wang S., Clemmons A., Ahn H.-S., and Boykow G. Biorg. Med. Chem. Lett. 5 (1995) 2005
56. Peitzonka T., Damon R., Russell M., and Wattanasin S. Biorg. Med. Chem. Lett. 6 (1996) 1951
57. Goldberg I.J. J.Lipid Res. 37 (1996) 693
58. Miesenböck G., Hölzl B., Föger B., Brandstätter E., Paulweber B., Sandhofer F., and Patsch J.R. J. Clin. Invest. 91 (1993) 448
59. Shimada M., Ishibashi S., Inaba T., Yagyu H., Harada K., Osuga J.-I., Ohashi K., Yazaki Y., and Yamada N. Proc. Natl. Acad. Sci USA 93 (1996) 7242
60. Chappell D.A., Fry G.L., Waknitz M.A., Muhonen L.E., Pladet M.W., Iverius P.H., and Strickland D.K. J. Biol. Chem. 268 (1993) 14168
61. Tsutsumi K., Inoue Y., Shima A., Iwasaki K., Kawamura M., and Murase T. J. Clin. Invest. 92 (1993) 411
62. Kurogi Y., Inoue Y., Tsutsumi K., Nakamura S., Nagao K., Yoshitsugu H., and Tsuda Y. J. Med. Chem. 39 (1996) 1433
63. Acton S., Rigotti A., Landschulz K.T., Xu S., Hobbs H.H., and Krieger M. Science 271 (1996) 518
64. Wang N., Weng W., Breslow J., and Tall A.R. J. Biol. Chem. 271 (1996) 21001
65. Rubin E.M., Kraus R.M., Spangler E.A., Verstuyft J.G., and Clift S.M. Nature 353 (1991) 265
66. Miyazaki A., Sakuma S., Morikawa W., Takiue T., Miake F., Terano T., Sakai M., Hakamata H., Sakamoto Y., Naito M., Ruan Y., Takahashi K., Ohta T., and Horiuchi S. Arterioscler. Thromb. Vasc. Biol. 15 (1995) 1882
67. Widom R.L., Ladias J.A.A., Kouidou S., and Karathanasis S.K. Mol. Cell. Biol. 11 (1991) 677
68. Haghpassand M., and Moberly J.B. Atherosclerosis 117 (1995) 199
69. Auwerx J., Schoonjans K., Fruchart J.-C., and Staels B. Atherosclerosis 124 suppl. (1996) S29
70. Raines E.W., and Ross R. BioEssays 18 (1996) 271
71. Libby P., Geng U.J., Aikawa M., Schoenbeck U., Mach F., Clinton S.K., Sukhova G.K., and Lee R.T. Curr. Opin. Lipidol. 7 (1996) 330
72. Williams K.J., and Tabas I. Arterioscler. Thromb. Vasc. Biol. 15 (1995) 551
73. Steinberg D., Parthasarathy S., Carew T.E., Khoo J.C., and Witztum J.L. N. Engl. J. Med. 320 (1989) 915
74. Berliner J.A., and Heinecke J.W. Free Radical Biol. Med. 20 (1996) 707
75. Stephens N.G., Parsons A., Schofield P.M., Kelly F., Cheeseman K., and Mitchinson M.J. Lancet 347 (1996) 781
76. Regnström J., Walldius G., Nilsson S., Schäfer L., Elinder, Johansson J., Mölgaard J., Holme I., Olsson A.G., and Nilsson J. Atherosclerosis 125 (1996) 217
77. Hennekens C.H. Eur. Heart J. 18 (1997) 177
78. Parker R.A., Bamhart R.L., Chen K.S., Edwards M.L., Matt Jr. J.E., Rhinehart B.L., Robinson K.M., Vaal M.J., and Yates M.T. Biorg. Med. Chem. Lett. 6 (1996) 1559
79. Gotteland J.-P., Delhon A., Junquéro D., Oms P., and Halazy S. Biorg. Med. Chem. Lett. 6 (1996) 533
80. Kühn H., Heydeck D., Hugou I., and Gniwotta C. J. Clin. Invest. 99 (1997) 888
81. Shen J., Herderick E., Cornhill J.F., Zsigmond E., Kim H.-S., Kühn H., Guevara N.V., and Chan L. J. Clin. Invest. 98 (1996) 2201
82. D. Harats, H. Kurihara, H. Levkovitz and E. Sigal, Abstracts, Keystone Symposia on Molecular and Cellular Biology, Inflammation, Growth-Regulatroy Molecules and Atherosclerosis, Keystone, CO, January 20-26: 29(1997)
83. Mackness M.I., and Durrington P.N. Atherosclerosis 115 (1995) 243