Inhibitors of acyl-CoA:Cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: An acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets

Journal of Medicinal Chemistry

Volumn 39, Issue 26, 1996, Pages 5031-5034

  Lee, Helen T ^a   Sliskovic, Drago R ^a   Picard, Joseph A ^a   Roth, Bruce D ^a   Wierenga, Wendell ^b   Hicks, James L ^a   Bousley, Richard F ^a   Hamelehle, Katherine L ^a   Homan, Reynold ^a   Speyer, Cecilia ^a   Stanfield, Richard L ^a   Krause, Brian R ^a  

^a PFIZER INC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AVASIMIBE; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HYPERCHOLESTEROLEMIA; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT;

ACETATES; ANIMALS; ANTICHOLESTEREMIC AGENTS; DIET; ENZYME INHIBITORS; RABBITS; RATS; STEROL O-ACYLTRANSFERASE; SULFONIC ACIDS;

EID: 0030472785     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960674d     Document Type: Article

References (21)

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