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Camptothecins: From Bench Research to Hospital Wards
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Potmesil, M.1
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0004442932
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U.S. Patent 4,943,579,1990
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(a) Rao Vishnuvajjala, B.; Garzon-Aburbeh, A. Water Soluble Prodrugs of Camptothecin. U.S. Patent 4,943,579,1990.
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Water Soluble Prodrugs of Camptothecin
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Rao Vishnuvajjala, B.1
Garzon-Aburbeh, A.2
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3
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0027435043
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Plant Antitumor Agents. 30. Synthesis and Structure Activity of Novel Camptothecin Analogs
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(b) Wall, M. E.; Wani, M. C.; Nicholas, A. W.; Manikumar, G.; Tele, C.; Moore, L.; Truesdale, A.; Leitner, P. and Besterman, J. M. Plant Antitumor Agents. 30. Synthesis and Structure Activity of Novel Camptothecin Analogs. J. Med. Chem. 1993, 36, 2689-2700.
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Wall, M.E.1
Wani, M.C.2
Nicholas, A.W.3
Manikumar, G.4
Tele, C.5
Moore, L.6
Truesdale, A.7
Leitner, P.8
Besterman, J.M.9
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4
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85062138081
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note
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4,5 we prefer the use of transport form in this case as it describes the performance of the PEG-camptothecin conjugate more accurately.
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5
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0030071043
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Drug Delivery Systems: Water Soluble Taxol-2′-Poly(ethylene glycol) Ester Prodrugs-Design and in Vivo Effectiveness
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Greenwald, R. B.; Gilbert, C. W.; Pendri, A.; Conover, C. D.; Xia, J. and Martinez, A., Drug Delivery Systems: Water Soluble Taxol-2′-Poly(ethylene glycol) Ester Prodrugs-Design and In Vivo Effectiveness. J. Med. Chem. 1996, 39, 424-431.
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Greenwald, R.B.1
Gilbert, C.W.2
Pendri, A.3
Conover, C.D.4
Xia, J.5
Martinez, A.6
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6
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0342697127
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Edited by Davis, S. S.; Ilium, L.; Tomlinson, E. Plenum Press: New York
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Bundgaard, H. Bioreversible Derivatization of Peptides. Delivery Systems for Peptide Drugs, Edited by Davis, S. S.; Ilium, L.; Tomlinson, E. Plenum Press: New York, 1986; pp 49-68.
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Bundgaard, H.1
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7
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85062128167
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note
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4
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8
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85062121518
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note
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Cures are defined as survival for ≥ 40 days.
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9
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0028998076
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Synthesis and Antitumor Activity of Novel Water Soluble Derivatives of Camptothecin as Specific Inhibitors of Topoisomerase
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Luzzio, M. J.; Besterman, J. M.; Emerson, D. L.; Evans, M. G.; Lackey, K.; Leitner, P. L.; McIntyre, G.; Morton, B.; Myers, P. L.; Peel, M.; Sisco, J. M.; Sternbach, D. D.; Tong, W. Q.; Truesdale, A.; Uehling, D. E.; Vuong, A. and Yates, J. Synthesis and Antitumor Activity of Novel Water Soluble Derivatives of Camptothecin as Specific Inhibitors of Topoisomerase. J. Med. Chem. 1995, 38, 395-401.
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Luzzio, M.J.1
Besterman, J.M.2
Emerson, D.L.3
Evans, M.G.4
Lackey, K.5
Leitner, P.L.6
McIntyre, G.7
Morton, B.8
Myers, P.L.9
Peel, M.10
Sisco, J.M.11
Sternbach, D.D.12
Tong, W.Q.13
Truesdale, A.14
Uehling, D.E.15
Vuong, A.16
Yates, J.17
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10
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0028896166
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Camptothecin and Taxol: Discovery to Clinic-Thirteenth Bruce F. Cain Memorial Award Lecture
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(a) Wall, M. E.; Wani, M. C. Camptothecin and Taxol: Discovery to Clinic-Thirteenth Bruce F. Cain Memorial Award Lecture. Cancer Res. 1995, 55, 753-760.
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Wall, M.E.1
Wani, M.C.2
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11
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0024560495
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Structure Activity Study of the Actions of Camptothecin Derivatives on Mammalian Topoisomerase I: Evidence for a Specific Receptor Site and a Relation to Tumor Activity
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(b) Jaxel, C.; Kohn, K. W.; Wani, M. C.; Wall, M. E.; Pommier, Y. Structure Activity Study of the Actions of Camptothecin Derivatives on Mammalian Topoisomerase I: Evidence for a Specific Receptor Site and a Relation to Tumor Activity. Ibid. 1989, 49, 1465-1469.
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Jaxel, C.1
Kohn, K.W.2
Wani, M.C.3
Wall, M.E.4
Pommier, Y.5
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12
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0024537205
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Modification of the Hydroxy Lactone Ring of Camptothecin: Inhibition of Mammalian Topoisomerase I and Biological Activity
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(c) Hertzberg, R. P.; Caranfa, M.; Holden, K. G.; Jakas, D. R.; Gallagher, G.; Mattern, M. R.; Mong, S.-H.; Bartus, J. O.; Johnson, R. K.; Kingsbury, W. D. Modification of the Hydroxy Lactone Ring of Camptothecin: Inhibition of Mammalian Topoisomerase I and Biological Activity. J. Med. Chem. 1989, 32, 715-720.
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Hertzberg, R.P.1
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Gallagher, G.5
Mattern, M.R.6
Mong, S.-H.7
Bartus, J.O.8
Johnson, R.K.9
Kingsbury, W.D.10
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13
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0028012774
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The Structural Basis of Camptothecin Interactions with Serum Albumin: Impact on Drug Stability
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Burke, T. G.; Mi, Z. The Structural Basis of Camptothecin Interactions with Serum Albumin: Impact on Drug Stability. J. Med. Chem. 1994, 37, 40-46.
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Burke, T.G.1
Mi, Z.2
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14
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0027930186
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Differential Interactions of Camptothecin Lactone and Carboxylate Forms with Human Blood Components
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Mi, Z.; Burke, T. G. Differential Interactions of Camptothecin Lactone and Carboxylate Forms with Human Blood Components. Biochemistry 1994, 33, 10325-10336.
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Biochemistry
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Mi, Z.1
Burke, T.G.2
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15
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7144248725
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Plant Antitumor Agents. I. the Isolation and Structure of Camptothecin a Novel Alkaloidal Leukemia and Tumor Inhibitor from "Camptotheca acuminata
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Wall, M. E.; Wani, M. C.; Cook, C. E.; Palmer, K. H.; McPhail, A. T.; Sim, G. A. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin a Novel Alkaloidal Leukemia and Tumor Inhibitor from "Camptotheca acuminata. J. Am. Chem. Soc. 1966, 88, 3888-3890.
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Wall, M.E.1
Wani, M.C.2
Cook, C.E.3
Palmer, K.H.4
McPhail, A.T.5
Sim, G.A.6
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16
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0028150946
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Marked Interspecies Variations Concerning the Interactions of Camptothecin with Serum Albumins: A Frequency - Domain Fluorescence Spectroscopic Study
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1 is known to undergo lactone ring opening to a much greater extent in human plasma than in other species, and HSA has been suggested as the plasma component responsible for promoting this rapid and extensive hydrolysis (Mi, Z; Burke, T. G. Marked Interspecies Variations Concerning the Interactions of Camptothecin with Serum Albumins: A Frequency - Domain Fluorescence Spectroscopic Study. Biochemistry 1994, 33, 12540-12545).
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Biochemistry
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Mi, Z.1
Burke, T.G.2
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